GEOGRAPHICAL INFORMATION SYSTEM FOR TOWNPLANNING LANDMARKS TOURISTIC USING AND PRESERVING

The center of the city usually forms its image and uniqueness among the other cities of a country, and possibly among the cities of the whole world. Every city has its own landmarks; in Ukraine big part of them are of Soviet heritage. For example, in Kharkiv there is the Ordzhonykydzevskij region that was formed in the years 20-30s of ?? century. The most interesting thing is that there are several central districts between the side-street called “Peace” and boulevard of Frunze. The districts started to be built in 1930 as a so-called socialistic small town-satellite “New Kharkiv”. This socialistic town should have been a place for workers of recently built Kharkiv tractor factory to live in. According to the project all the houses in the districts should have been connected by transitions, which were planned to be built from the reinforced concrete and glass at the level of the second floor (it was not realized because of lack of money). Apartments in the “socialistic paradise” should not have had the specially equipped kitchens: all the inhabitants of “New Kharkiv” (planned number of about 50 thousand people) were to be fully served by establishments of public food consumption - so called “factory-kitchens”.Geographical Information System; Landmark; Town-planning; City.

The Content of Heavy Metals, Arsenic, and Aluminum in Mint Leaves and Products

Mint is a medicinal herbal drug; and its leaves are also widely used in the food and cosmetic industries. Medical literature states that mint is naturally resistant to toxic elements and capable of accumulating them in significant amounts. The aim of the study was to compare heavy metals, arsenic, and aluminum contents in mint leaves and products. Materials and methods: the study covered peppermint leaves, tinctures, and oils, as well as teas and dietary supplements made of different varieties of mint. Elemental analysis was performed according to the procedure of inductively coupled plasma mass spectrometry (ICP-MS) developed by the authors. Results: the authors studied the compliance of the experimentally established contents of heavy metals, arsenic, and aluminum in peppermint leaves and products to the requirements of Russian and foreign regulatory documentation. Nonparametric Spearman correlation coefficients were calculated to characterise the interaction between chemical elements. Conclusions: arsenic contents in mint leaves may exceed the limit given in the State Pharmacopoeia of the Russian Federation, 14th ed. It is supposed that the increased contents are not a result of the anthropogenic factor, but a specific characteristic of this plant. The study demonstrated synergistic absorption of aluminum, iron, and vanadium, as well as copper and zinc by mint. It was established that manganese had an antagonistic effect on the absorption of nickel, lead, and cobalt by mint

Determination of Heavy Metals, Arsenic, and Aluminum Content in Pumpkin Seed Herbal Substance and Native Products, by Inductively Coupled Plasma Mass Spectrometry

Pumpkin seeds belong to the so-called native products. Their characteristic feature is that they can be consumed directly, without prior extraction of the starting material. All elemental toxicants contained in pumpkin seeds are transferred in full to the native product. Therefore, it is important to study specific aspects of elemental toxicant accumulation by pumpkin seeds.The aim of the study was to determine the content of heavy metals, As, and Al in pumpkin seed herbal substance and native products, and to assess the degree of accumulation of these elements, depending on the vegetation area.Materials and methods: the study evaluated pumpkin seed native products by Russian manufacturers as well as pumpkin seeds harvested in areas with different anthropogenic load. The sample preparation was performed by microwave digestion, and the determination of the elemental toxicants was perfomed by inductively coupled plasma mass spectrometry.Results: the pumpkin seeds were shown to contain essential, probably essential, potentially toxic, and toxic elements. The authors performed comparative analysis of the elemental composition of pumpkin seeds as well as seeds, grains, and beans of various oil-bearing, grain, and leguminous crops.Conclusions: the content of the specified elemental toxicants (As, Cd, Hg, Pb) in the tested samples of pumpkin seed herbal substance and herbal medicinal products did not exceed the limits established by the Russian Pharmacopoeia. The unspecified toxic elements were either absent in pumpkin seeds (Tl) or found in trace amounts (Al). The content of a number of essential elements (Zn, Fe, Mn, Cu, Mo, Cr) in pumpkin seeds was higher than in the seeds of many oil-bearing crops. The vegetation area had no significant influence on the content of the tested elements in the pumpkin seeds. Pumpkin seeds are capable of accumulating abnormally high amounts of Cd, Co, and Ni in areas with high environmental pollution

СВЯЗЬ МЕЖДУ ОДНОСОЛИТОННЫМИ СОСТАВЛЯЮЩИМИ ДВУХСОЛИТОННОГО РЕШЕНИЯ УРАВНЕНИЯ КОРТЕВЕГА-ДЕ ФРИЗА

The system of third-order nonlinear differential equations for components of two-soliton solution of the Korteweg-de Vries equation at t → ± ∞ is constructed. The equation describing the relation between these components is derived, and a general solution of this equation is obtained for one special case.Построена система нелинейных обыкновенных дифференциальных уравнений третьего порядка, описывающая поведение составляющих двухсолитонного решения уравнения Кортевега-де Фриза при t → ± ∞. Получено нелинейное уравнение связи между этими составляющими и для одного частного случая найдено его общее решение

Filovirus refseq entries: Evaluation and selection of filovirus type variants, Type sequences, And names

Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists. Sequencing duration and costs are rapidly decreasing, sequencing hardware is under modification for use by non-experts, and software is constantly being improved to simplify sequence data management and analysis. Thus, analysis of virus disease outbreaks on the molecular level is now feasible, including characterization of the evolution of individual virus populations in single patients over time. The increasing accumulation of sequencing data creates a management problem for the curators of commonly used sequence databases and an entry retrieval problem for end users. Therefore, utilizing the data to their fullest potential will require setting nomenclature and annotation standards for virus isolates and associated genomic sequences. The National Center for Biotechnology Information's (NCBI's) RefSeq is a non-redundant, curated database for reference (or type) nucleotide sequence records that supplies source data to numerous other databases. Building on recently proposed templates for filovirus variant naming [<virus name> (<strain>)/<isolation host-suffix>/<country of sampling>/<year of sampling>/<genetic variant designation>-<isolate designation>], we report consensus decisions from a majority of past and currently active filovirus experts on the eight filovirus type variants and isolates to be represented in RefSeq, their final designations, and their associated sequences.Other co-authors: Ralf G. Dietzgen, Norman A. Doggett, Olga Dolnik, John M. Dye, Sven Enterlein, Paul W. Fenimore, Pierre Formenty, Alexander N. Freiberg, Robert F. Garry, Nicole L. Garza, Stephen K. Gire, Jean-Paul Gonzalez, Anthony Griffiths, Christian T. Happi, Lisa E. Hensley, Andrew S. Herbert, Michael C. Hevey, Thomas Hoenen, Anna N. Honko, Georgy M. Ignatyev, Peter B. Jahrling, Joshua C. Johnson, Karl M. Johnson, Jason Kindrachuk, Hans-Dieter Klenk, Gary Kobinger, Tadeusz J. Kochel, Matthew G. Lackemeyer, Daniel F. Lackner, Eric M. Leroy, Mark S. Lever, Elke Mühlberger, Sergey V. Netesov, Gene G. Olinger, Sunday A. Omilabu, Gustavo Palacios, Rekha G. Panchal, Daniel J. Park, Jean L. Patterson, Janusz T. Paweska, Clarence J. Peters, James Pettitt, Louise Pitt, Sheli R. Radoshitzky, Elena I. Ryabchikova, Erica Ollmann Saphire, Pardis C. Sabeti, Rachel Sealfon, Aleksandr M. Shestopalov, Sophie J. Smither, Nancy J. Sullivan, Robert Swanepoel, Ayato Takada, Jonathan S. Towner, Guido van der Groen, Viktor E. Volchkov, Valentina A. Volchkova, Victoria Wahl-Jensen, Travis K. Warren, Kelly L. Warfield, and Stuart T. Nichol Output Type: Lette

Содержание тяжелых металлов, мышьяка и алюминия в листьях мяты и продуктах на их основе

Mint is a medicinal herbal drug; and its leaves are also widely used in the food and cosmetic industries. Medical literature states that mint is naturally resistant to toxic elements and capable of accumulating them in significant amounts. The aim of the study was to compare heavy metals, arsenic, and aluminum contents in mint leaves and products. Materials and methods: the study covered peppermint leaves, tinctures, and oils, as well as teas and dietary supplements made of different varieties of mint. Elemental analysis was performed according to the procedure of inductively coupled plasma mass spectrometry (ICP-MS) developed by the authors. Results: the authors studied the compliance of the experimentally established contents of heavy metals, arsenic, and aluminum in peppermint leaves and products to the requirements of Russian and foreign regulatory documentation. Nonparametric Spearman correlation coefficients were calculated to characterise the interaction between chemical elements. Conclusions: arsenic contents in mint leaves may exceed the limit given in the State Pharmacopoeia of the Russian Federation, 14th ed. It is supposed that the increased contents are not a result of the anthropogenic factor, but a specific characteristic of this plant. The study demonstrated synergistic absorption of aluminum, iron, and vanadium, as well as copper and zinc by mint. It was established that manganese had an antagonistic effect on the absorption of nickel, lead, and cobalt by mint.Листья мяты являются лекарственным растительным сырьем, а также используются в пищевой и косметической промышленности. В литературе высказано предположение, что мята характеризуется природной устойчивостью к элементам-токсикантам и способна накапливать их в заметных количествах. Цель работы: проведение сравнительного анализа содержания тяжелых металлов, мышьяка и алюминия в листьях мяты и продуктах их переработки. Материалы и методы. В качестве объектов исследования использовали листья мяты перечной, настойки и масла на их основе, а также сухие чаи и БАД из различных видов мяты. Элементный анализ проводили методом масс-спектрометрии с индуктивно-связанной плазмой по разработанной авторами данного исследования методике. Результаты. Изучено соответствие экспериментально установленного содержания тяжелых металлов, мышьяка, алюминия в листьях мяты и продуктах их переработки требованиям отечественной и зарубежной нормативной документации. Для характеристики взаимодействия между химическими элементами рассчитаны непараметрические коэффициенты корреляции Спирмена. Выводы. Уровень содержания мышьяка в листьях мяты в ряде случаев превышает норму, приведенную в Государственной фармакопее Российской Федерации XIV изд. Предположительно такое превышение не связано с действием антропогенного фактора, а является специфической характеристикой данного растения. Установлен синергизм поглощения мятой алюминия, железа и ванадия, а также меди и цинка. Показано, что марганец оказывает антагонистическое действие на поглощение мятой никеля, свинца и кобальта

Определение методом масс-спектрометрии с индуктивно связанной плазмой содержания тяжелых металлов, мышьяка и алюминия в лекарственном растительном сырье «Тыквы семена» и нативных продуктах на его основе

Pumpkin seeds belong to the so-called native products. Their characteristic feature is that they can be consumed directly, without prior extraction of the starting material. All elemental toxicants contained in pumpkin seeds are transferred in full to the native product. Therefore, it is important to study specific aspects of elemental toxicant accumulation by pumpkin seeds.The aim of the study was to determine the content of heavy metals, As, and Al in pumpkin seed herbal substance and native products, and to assess the degree of accumulation of these elements, depending on the vegetation area.Materials and methods: the study evaluated pumpkin seed native products by Russian manufacturers as well as pumpkin seeds harvested in areas with different anthropogenic load. The sample preparation was performed by microwave digestion, and the determination of the elemental toxicants was perfomed by inductively coupled plasma mass spectrometry.Results: the pumpkin seeds were shown to contain essential, probably essential, potentially toxic, and toxic elements. The authors performed comparative analysis of the elemental composition of pumpkin seeds as well as seeds, grains, and beans of various oil-bearing, grain, and leguminous crops.Conclusions: the content of the specified elemental toxicants (As, Cd, Hg, Pb) in the tested samples of pumpkin seed herbal substance and herbal medicinal products did not exceed the limits established by the Russian Pharmacopoeia. The unspecified toxic elements were either absent in pumpkin seeds (Tl) or found in trace amounts (Al). The content of a number of essential elements (Zn, Fe, Mn, Cu, Mo, Cr) in pumpkin seeds was higher than in the seeds of many oil-bearing crops. The vegetation area had no significant influence on the content of the tested elements in the pumpkin seeds. Pumpkin seeds are capable of accumulating abnormally high amounts of Cd, Co, and Ni in areas with high environmental pollution.Семена тыквы относятся к нативным продуктам. Их характерная особенность заключается в том, что они могут потребляться напрямую, без предварительной экстракции исходного сырья. Количество элементных токсикантов в исходном лекарственном сырье полностью соответствует таковому в нативном продукте. В связи с этим изучение особенностей накопления элементных токсикантов семенами тыквы является актуальным.Цель работы — определение содержания тяжелых металлов, As и Al в лекарственном растительном сырье и нативных продуктах «Семена тыквы» и оценка степени накопления этих элементов в зависимости от места произрастания.Материалы и методы: в качестве объектов исследования использовали нативные продукты «Семена тыквы» отечественных производителей, а также семена тыквы, собранные в местах с различной антропогенной нагрузкой. Пробоподготовку проводили методом микроволнового разложения, анализ содержания элементов — методом масс-спектрометрии с индуктивно связанной плазмой.Результаты: экспериментально установлено содержание эссенциальных, условно эссенциальных, потенциально токсичных и токсичных элементов в семенах тыквы. Проведен сравнительный анализ элементного состава семян тыквы и семян, зерен и бобов различных масличных, зерновых и зернобобовых сельскохозяйственных культур.Выводы: содержание нормируемых элементных токсикантов (As, Cd, Hg, Pb) в  исследованных образцах лекарственного растительного сырья и лекарственных растительных препаратов «Тыквы семена» не превышает норм, установленных отечественной фармакопеей. Ненормируемые токсичные элементы либо не присутствуют в семенах тыквы (Tl), либо присутствуют в незначительных количествах (Al). Содержание ряда эссенциальных элементов (Zn, Fe, Mn, Cu, Mo, Cr) в семенах тыквы выше, чем в семенах многих масличных культур. Место произрастания тыквы не оказывает существенного влияния на содержание исследованных элементов в семенах тыквы. В условиях сильного загрязнения окружающей среды семена тыквы способны накапливать аномально высокие количества Cd, Co и Ni

Preliminary Analysis of the Dynamic Structure of Near-Earth Space and Orbital Debris Location with the Aim of Finding the Possible Utilization Orbit of Artificial Earth Satellites

В работе представлены результаты исследования динамической структуры околоземного пространства, расположенного в диапазоне больших полуосей от 8 000 до 45 000 км, методом численного моделирования. Выявлены зоны подверженные наибольшему влиянию вековых резонансов. Показано расположение реальных объектов из каталога NORAD и влияние на них резонансов различных типов. Выделены области наиболее подходящие для утилизации отработавших ИСЗ.The paper presents the results of a study of the dynamic structure of the near-Earth orbital space located in the semi-major axes range from 8 000 to 45 000 km using the numerical simulation method. The zones subject to the greatest influence of secular resonances are revealed. The location of real objects from the NORAD catalog and the influence of different types of resonances on them is shown. The most suitable areas for the disposal of defunct satellites are identified.Исследование выполнено за счет гранта Российского научного фонда № 19-72-10022, https://rscf.ru/project/19-72-10022/

Genomic Characterization and High Prevalence of Bocaviruses in Swine

Using random PCR amplification followed by plasmid subcloning and DNA sequencing, we detected bocavirus related sequences in 9 out of 17 porcine stool samples. Using primer walking, we sequenced the nearly complete genomes of two highly divergent bocaviruses we provisionally named porcine bocavirus 1 isolate H18 (PBoV1-H18) and porcine bocavirus 2 isolate A6 (PBoV2-A6) which differed by 51.8% in their NS1 protein. Phylogenetic analysis indicated that PBoV1-H18 was very closely related to a ∼2 Kb central region of a porcine bocavirus-like virus (PBo-LikeV) from Sweden described in 2009. PBoV2-A6 was very closely related to the porcine bocavirus genomes PBoV-1 and PBoV2 from China described in 2010. Among 340 fecal samples collected from different age, asymptomatic swine in five Chinese provinces, the prevalence of PBoV1-H18 and PBoV2-A6 related viruses were 45–75% and 55–70% respectively, with 30–47% of pigs co-infected. PBoV1-A6 related strains were highly conserved, while PBoV2-H18 related strains were more diverse, grouping into two genotypes corresponding to the previously described PBoV1 and PBoV2. Together with the recently described partial bocavirus genomes labeled V6 and V7, a total of three major porcine bocavirus clades have therefore been described to date. Further studies will be required to elucidate the possible pathogenic impact of these diverse bocaviruses either alone or in combination with other porcine viruses