Regretting fatherhood in Spain

Objective: In this first study of its kind in Spain, we analyse the scope of and reasons underlying paternal regret. Background: Research on parental regret, a subject only recently broached by analysts, tends to focus on motherhood. Regretting fatherhood has been only scantly researched. In this study we test the effects of intensive fathering, the use of different care resources, economic and employment conditions, and satisfaction with respondents’ partnership on their regret for having children. Method: The analysis is based on an online survey of parents of children under 7 years old (QUIDAN Survey) A total of 3100 parents were interviewed, with the sample evenly distributed by sex and youngest child’s age, and proportional by parents’ highest level of schooling and place of residence. The weighted subsample used in this article included 1374 fathers. The hypotheses are tested with logistic regression. Results: The social factors associated with a greater likelihood of regret include circumstances that challenge men’s role as primary breadwinner, a negative impact of fatherhood on job career, a high dependence on grandparents for balancing working and private lives and partnership dissatisfaction. A relationship between intensive fathering and regret could not be observed. Conclusion: The findings show the extent of paternal regret to be fairly limited, similar to the proportion reported for maternal regret. Paternal regret is mainly associated with family and working circumstancesThe research was funded by the Spanish Research Agency under the project ‘Childcare practices among Spanish families with children less than seven years old: Agents, practices and satisfaction’, grant number CSO2017-84634-

Policemen on Leave Alone in Spain. A Rift in Hegemonic Masculinity?

Caring fatherhood in very traditional and masculinized environments has been under-researched. This study analyzed the experience of Spanish policemen who used parental leave to care for their babies alone while their partners returned to paid work. The aim was to ascertain whether use of parental leaves under those circumstances favors the development of caring masculinity. The qualitative methodology deployed consisted in semi-structured interviews conducted in 2014 with a sample of 15 policemen who took parental leave alone for at least 4 weeks while their partners returned to paid work. More specifically, the analysis addressed the respondents’ discourse on the justification of their decision to engage in this type of childcare, the workplace reaction to the decision, and their experience when fathering alone. The findings suggest that, even though hegemonic masculinity persisted in part of these fathers’ discourse and experience, engagement in such innovative practice tended to narrow the divide between traditional and caring masculinity. The conclusion drawn is that encouraging fathers to take leave to care for their children alone is a useful tool for furthering caring masculinity in highly masculinized environmentsThis paper is been done in the framework of two competitive research projects: CSO2013-44097-R Fathers on Parental Leave Alone and CSO2017-84634-R Childcare practices among families in Spain: Agents, practices and satisfactio

Grandparents' role in Spanish families' work/life balance strategies

In recent years, grandparental childcare has been instrumental to Spanish parents’ ability to engage in paid work. At the same time, the use of formal childcare services, paid domestic assistance and parental leave-taking have also intensified. The objectives of this study are: (1) to estimate the scope of the support received from grandparents in caring for children; and (2) to assess the impact of the diversification of childcare resources on highly frequent grandparental childcare in two-parent families. The sample covered the 2304 parents with at least one child under 13 interviewed on the occasion of the Survey on the Use of Parental Leave in Spain, 2012. Three types of factors were analysed: (1) use of external childcare resources; (2) time devoted by parents to childcare and paid work; and (3) control factors measuring grandparents’ availability, childcare needs and income. The findings suggested that international comparative studies based on the Survey of Health, Ageing and Retirement in Europe (SHARE) underestimate the scope of grandparental childcare. Two-parent families with higher incomes resorted less frequently to grandparental childcare. In addition, formal childcare services, paid domestic work and parental leaves are associated with less frequent grandparental involvement. Overall, the findings suggest that more diversified deployment of the available resources may contribute to reducing grandparental childcar

Is Spanish parental leave 'traditionalising' the gender distribution of childcare and housework?

Objective: The question addressed in this study is the possible effect of mothers' use of parental leave on the share of childcare and housework assumed by each parent. Background: Whilst the length of parental leave is greater in Spain than in other European countries, as it is unpaid, take-up rates are low. Such leaves are taken more frequently and for longer periods by women than men. Method: To determine the answer, two multivariate regression models were applied to National Statistics Institute 2018 Fertility Survey data. The main independent variables were fathers' and mothers' use of parental leave. The models also controlled for the effects of family and socio-economic variables on the share of childcare and housework assumed by each parent. Results: The findings showed that mothers' use of unpaid full-time parental leave traditionalises the distribution of domestic chores only when the leave extends beyond one year, whereas part-time leave-taking has no effect whatsoever. That such reversion to tradition can be neutralised when fathers take leaves attests to the advisability of encouraging paternal use. The effects apply to childcare only, however, for other household chores are still distributed along very traditional lines. Conclusion: Unpaid parental leave use by mothers "traditionalizes" the allocation of childcare within the couple, but only when it takes longer than a yearThis study was funded by the Agencia Estatal de Investigación under Grant CSO2017-84634-

The Impact of Paternity Leave Compared to Unemployment on Child Care and Housework Distribution in Spain

Paternity leave has been introduced in many countries as a way to foster father´s co-responsibility in family obligations. This study aims \to analyse, for the Spanish case, if (1) the positive effects of the paternity leave are not only limited to the short term, but are maintained at medium and long term; (2) if a similar effect applies in the case of unemployment periods. Based on a subsample of 3388 cases derived from the Spanish Fertility Survey 2018, we perform OLS regression analysis of father´s involvement in childcare and housework. Our analysis shows that longer leaves are related to a greater involvement in care and housework activities, although only in the former, the effect is maintained in the long term. Regarding unemployed fathers, these individuals show more involvement in childcare during the first year, but the effect vanishes later and there is no significant relationship with housewor

Estudio y parametrización de pruebas de evaluación para su implementación en docencia virtual

[SPA]Esta comunicación describe los trabajos que se están realizando en el seno de un proyecto de innovación docente (PID) desarrollado por profesores de la Universidad de Jaén (UJA). Este PID lleva a cabo un estudio y parametrización de pruebas de evaluación tipo para su incorporación a la plataforma de docencia virtual ILIAS a través de objetos multimedia interactivos. Se ha realizado un estudio y documentación de las herramientas de evaluación que presenta ILIAS, concretamente de los tests y de todos los tipos de preguntas de tests que presenta la plataforma con el fin de dar a conocerlos y fomentar su uso. Una vez conocidas las herramientas de evaluación, se solicitará al profesorado que informe de las deficiencias y carencias que hayan detectado con el fin de poder proponer nuevos tipos y modelos de pruebas de evaluación. El objetivo final del proyecto es elaborar o adaptar un lenguaje de especificación que pueda describir todos los tipos de pruebas de evaluación existentes y demandadas por el profesorado, así como crear una base de datos con todas las aportaciones que se reciban. Para ello se debe obtener una parametrización genérica de todos los tipos de pregunta de evaluación. [ENG]This paper describes the work being carried out based on a teaching innovation project (TIP), it is being developed by professors at the University of Jaén (UJA). This TIP makes a study and parameterization of evaluation test types for its inclusion into the ILIAS LMS through interactive multimedia objects. In order to disseminate and promote the use of assessment tools offered by ILIAS, the tests and all types of questions on the platform have been studied and documented. Once assessment tools are known, teachers will be asked to report the deficiencies and shortcomings that have been identified with the aim of proposing new types and models of tests. The ultimate aim is to develop a specification model that can describe existing and requested test types so that a database may be created with all the contributions received from the professors. This requires obtaining a generic parameterization of all test question types.Campus Mare Nostrum, Universidad Politécnica de Cartagena, Universidad de Murcia, Región de Murci

Deletion of chromosomal region 8p21 confers resistance to Bortezomib and is associated with upregulated Decoy trail receptor expression in patients with multiple myeloma

Loss of the chromosomal region 8p21 negatively effects survival in patients with multiple myeloma (MM) that undergo autologous stem cell transplantation (ASCT). In this study, we aimed to identify the immunological and molecular consequences of del(8)(p21) with regards to treatment response and bortezomib resistance. In patients receiving bortezomib as a single first line agent without any high-dose therapy, we have observed that patients with del(8)(p21) responded poorly to bortezomib with 50% showing no response while patients without the deletion had a response rate of 90%. In vitro analysis revealed a higher resistance to bortezomib possibly due to an altered gene expression profile caused by del(8)(p21) including genes such as TRAIL-R4, CCDC25, RHOBTB2, PTK2B, SCARA3, MYC, BCL2 and TP53. Furthermore, while bortezomib sensitized MM cells without del(8)(p21) to TRAIL/APO2L mediated apoptosis, in cells with del(8)(p21) bortezomib failed to upregulate the pro-apoptotic death receptors TRAIL-R1 and TRAIL-R2 which are located on the 8p21 region. Also expressing higher levels of the decoy death receptor TRAIL-R4, these cells were largely resistant to TRAIL/APO2L mediated apoptosis. Corroborating the clinical outcome of the patients, our data provides a potential explanation regarding the poor response of MM patients with del(8)(p21) to bortezomib treatment. Furthermore, our clinical analysis suggests that including immunomodulatory agents such as Lenalidomide in the treatment regimen may help to overcome this negative effect, providing an alternative consideration in treatment planning of MM patients with del(8)(p21)

Molecular signatures for CCN1, p21 and p27 in progressive mantle cell lymphoma

Mantle cell lymphoma (MCL) is a comparatively rare non-Hodgkin’s lymphoma characterised by overexpression of cyclin D1.Many patients present with or progress to advanced stage disease within 3 years. MCL is considered an incurable disease withmedian survival between 3 and 4 years. We have investigated the role(s) of CCN1 (CYR61) and cell cycle regulators inprogressive MCL. We have used the human MCL cell lines REC1 G519 > JVM2 cells by RQ-PCR, depicting a decrease in CCN1expression with disease progression. Investigation of CCN1 isoform expression by western blotting showed that whilst expres-sion of full-length CCN1 was barely altered in the cell lines, expression of truncated forms (18–20 and 28–30 kDa) decreasedwith disease progression. We have then demonstrated that cyclin D1 and cyclin dependent kinase inhibitors (p21CIP1and p27KIP1)are also involved in disease progression. Cyclin D1 was highly expressed in REC1 cells (OD: 1.0), reduced to one fifth in G519cells (OD: 0.2) and not detected by western blotting in JVM2 cells. p27KIP1followed a similar profile of expression as cyclin D1.Conversely, p21CIP1was absent in the REC1 cells and showed increasing expression in G519 and JVM2 cells. Subcellularlocalization detected p21CIP1/p27KIP1primarily within the cytoplasm and absent from the nucleus, consistent with altered roles in treatment resistance. Dysregulation of the CCN1 truncated forms are associated with MCL progression. In conjunction withreduced expression of cyclin D1 and increased expression of p21, this molecular signature may depict aggressive disease andtreatment resistance