Nocturia as an Unrecognized Symptom of Uncontrolled Hypertension in Black Men Aged 35 to 49 Years.

Background Hypertension is assumed to be asymptomatic. Yet, clinically significant nocturia (≥2 nightly voids) constitutes a putative symptom of uncontrolled hypertension. Black men with hypertension may be prone to nocturia because of blunted nocturnal blood pressure ( BP ) dipping, diuretic drug use for hypertension, and comorbidity that predisposes to nocturia. Here, we test the hypothesis that nocturia is a common and potentially reversible symptom of uncontrolled hypertension in black men. Methods and Results We determined the strength of association between nocturia (≥2 nightly voids) and high BP (≥135/85 mm Hg) by conducting in-person health interviews and measuring BP with an automated monitor in a large community-based sample of black men in their barbershops. Because nocturia is prevalent and steeply age-dependent after age 50 years, we studied men aged 35 to 49 years. Among 1673 black men (mean age, 43±4 years [ SD ]), those with hypertension were 56% more likely than men with normotension to have nocturia after adjustment for diabetes mellitus and sleep apnea (adjusted odds ratio, 1.56; 95% CI , 1.25-1.94 [ P<0.0001]). Nocturia prevalence varied by hypertension status, ranging from 24% in men with normotension to 49% in men whose hypertension was medically treated but uncontrolled. Men with untreated hypertension were 39% more likely than men with normotension to report nocturia ( P=0.02), whereas men whose hypertension was treated and controlled were no more likely than men with normotension to report nocturia ( P=0.69). Conclusions Uncontrolled hypertension was an independent determinant of clinically important nocturia in a large cross-sectional community-based study of non-Hispanic black men aged 35 to 49 years. Clinical Trial Registration URL : http://www.clinicaltrials.gov . Unqiue identifier: NCT 02321618

Alimentos funcionais: a saúde que vem do 'prato'.

bitstream/item/58951/1/alimentos-funcionais-ReciclandoIdeias10.pd

Ética na Embrapa.

bitstream/item/62074/1/ReciclandoIdeias13-Etica.pd

The steady state quantum statistics of a non-Markovian atom laser

We present a fully quantum mechanical treatment of a single-mode atomic cavity with a pumping mechanism and an output coupling to a continuum of external modes. This system is a schematic description of an atom laser. In the dilute limit where atom-atom interactions are negligible, we have been able to solve this model without making the Born and Markov approximations. When coupling into free space, it is shown that for reasonable parameters there is a bound state which does not disperse, which means that there is no steady state. This bound state does not exist when gravity is included, and in that case the system reaches a steady state. We develop equations of motion for the two-time correlation in the presence of pumping and gravity in the output modes. We then calculate the steady-state output energy flux from the laser.Comment: 14 pages (twocloumn), 6 figure

Electrostatics of ions inside the nanopores and trans-membrane channels

A model of a finite cylindrical ion channel through a phospholipid membrane of width $L$ separating two electrolyte reservoirs is studied. Analytical solution of the Poisson equation is obtained for an arbitrary distribution of ions inside the trans-membrane pore. The solution is asymptotically exact in the limit of large ionic strength of electrolyte on the two sides of membrane. However, even for physiological concentrations of electrolyte, the electrostatic barrier sizes found using the theory are in excellent agreement with the numerical solution of the Poisson equation. The analytical solution is used to calculate the electrostatic potential energy profiles for pores containing charged protein residues. Availability of a semi-exact interionic potential should greatly facilitate the study of ionic transport through nanopores and ion channels

Irreducible characters of GSp(4, q) and dimensions of spaces of fixed vectors

In this paper, we compute the conjugacy classes and the list of irreducible characters of GSp(4,q), where q is odd. We also determine precisely which irreducible characters are non-cuspidal and which are generic. These characters are then used to compute dimensions of certain subspaces of fixed vectors of smooth admissible non-supercuspidal representations of GSp(4,F), where F is a non-archimedean local field of characteristic zero with residue field of order q.Comment: 48 pages, 21 tables. Corrected an error in Table 16 for type V* representations (theta_11 and theta_12 were switched

Measuring decision quality: psychometric evaluation of a new instrument for breast cancer chemotherapy

Background: Women diagnosed with early stage (I or II) breast cancer face a highly challenging decision – whether or not to undergo adjuvant chemotherapy. We developed a decision quality instrument for chemotherapy for early stage breast cancer and sought to evaluate its performance. Methods: Cross-sectional, mailed survey of recent breast cancer survivors, providers, and healthy controls and a retest survey of survivors. The decision quality instrument includes questions on knowledge and personal goals. It results in a knowledge score and concordance score, which reflects the percentage of patients who received treatments that match their goals. Hypotheses related to acceptability, feasibility, validity, and reliability of the survey instrument were examined. Results: Responses were received from 352 patients, 89 providers and 35 healthy controls. The decision quality instrument was feasible to implement with few missing data. The knowledge scores had good retest reliability (intraclass correlation coefficient (ICC) =0.75). Knowledge scores discriminated between providers and patients (mean difference 31.1%, 95% CI 26.9, 35.3) and between patients and healthy controls (mean difference 11.2, 95% CI 5.4, 17.1). Most providers reported that the knowledge items covered essential content. Two of the five goal items had a ceiling effect, and one goal had low content validity. The goal items had moderate retest reliability (ICC’s 0.57 to 0.78). In the multivariable model of treatment, none of the patient goals was associated with receipt of chemotherapy. Age and hormone receptor status were the only variables independently associated with chemotherapy. Most patients (77.6%) had treatment concordant with that predicted by the model. Patients who had concordant treatment had similar levels of confidence and regret as those who did not. Conclusions: The Decision Quality Instrument is a reliable and valid measure of patient knowledge about chemotherapy, but its ability to measure concordance with patient goals is limited. In this sample, patient goals were not associated with treatment, and most patients reported they were not asked their preference, suggesting that goals were not adequately considered in decision making

Atypical knemidokoptosis in two Dunnocks (Prunella modularis) in southern England

Avian knemidokoptosis, caused by knemidokoptid mites (Knemidokoptinae: Epidermoptidae), has been reported in wild and domestic birds globally. We report two cases of severe knemidokoptosis in Dunnocks (Prunella modularis) from separate sites in Great Britain, where the disease has previously been reported predominantly in finches and, less frequently, in corvids

Output of a pulsed atom laser

We study the output properties of a pulsed atom laser consisting of an interacting Bose-Einstein condensate (BEC) in a magnetic trap and an additional rf field transferring atoms to an untrapped Zeeman sublevel. For weak output coupling we calculate the dynamics of the decaying condensate population, of its chemical potential and the velocity of the output atoms analytically.Comment: 4 pages, RevTeX. Full ps file available on http://mpqibmr1.mpq.mpg.de:5000/~man

ESO Imaging Survey: infrared observations of CDF-S and HDF-S

This paper presents infrared data obtained from observations carried out at the ESO 3.5m New Technology Telescope (NTT) of the Hubble Deep Field South (HDF-S) and the Chandra Deep Field South (CDF-S). These data were taken as part of the ESO Imaging Survey (EIS) program, a public survey conducted by ESO to promote follow-up observations with the VLT. In the HDF-S field the infrared observations cover an area of ~53 square arcmin, encompassing the HST WFPC2 and STIS fields, in the JHKs passbands. The seeing measured in the final stacked images ranges from 0.79" to 1.22" and the median limiting magnitudes (AB system, 2" aperture, 5sigma detection limit) are J_AB~23.0, H_AB~22.8 and K_AB~23.0 mag. Less complete data are also available in JKs for the adjacent HST NICMOS field. For CDF-S, the infrared observations cover a total area of \~100 square arcmin, reaching median limiting magnitudes (as defined above) of J_AB~23.6 and K_AB~22.7 mag. For one CDF-S field H-band data are also available. This paper describes the observations and presents the results of new reductions carried out entirely through the un-supervised, high-throughput EIS Data Reduction System and its associated EIS/MVM C++-based image processing library developed, over the past 5 years, by the EIS project and now publicly available. The paper also presents source catalogs extracted from the final co-added images which are used to evaluate the scientific quality of the survey products, and hence the performance of the software. This is done comparing the results obtained in the present work with those obtained by other authors from independent data and/or reductions carried out with different software packages and techniques. The final science-grade catalogs and co-added images are available at CDS.Comment: Accepted for publication in A&A, 13 pages, 12 figures; a full resolution version of the paper is available from http://www.astro.ku.dk/~lisbeth/eisdata/papers/4528.pdf ; related catalogs and images are available through http://www.astro.ku.dk/~lisbeth/eisdata