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Kinosternon integrum
Number of Pages: 6Integrative BiologyGeological Science
Guadalupe pluton–Mariposa Formation age relationships in the southern Sierran Foothills: Onset of Mesozoic subduction in northern California?
We report a new 153 ± 2 Ma SIMS U-Pb date for zircons from the hypabyssal Guadalupe pluton which crosscuts and contact metamorphoses upper crustal Mariposa slates in the southern Sierra. A ~950 m thick section of dark metashales lies below sandstones from which clastic zircons were analyzed at 152 ± 2 Ma. Assuming a compacted depositional rate of ~120 m/Myr, accumulation of Mariposa volcanogenic sediments, which overlie previously stranded Middle Jurassic and older ophiolite + chert-argillite belts in the Sierran Foothills, began no later than ~160 Ma. Correlative Oxfordian-Kimmeridgian strata of the Galice Formation occupy a similar position in the Klamath Mountains. We speculate that the Late Jurassic was a time of transition from (1) a mid-Paleozoic–Middle Jurassic interval of mainly but not exclusively strike-slip and episodic docking of oceanic terranes; (2) to transpressive plate underflow, producing calcalkaline igneous arc rocks ± outboard blueschists at ~170–150 Ma, whose erosion promoted accumulation of the Mariposa-Galice overlap strata; (3) continued transpressive underflow attending ~200 km left-lateral displacement of the Klamath salient relative to the Sierran arc at ~150–140 Ma and development of the apparent polar wander path cusps for North and South America; and (4) then nearly orthogonal mid and Late Cretaceous convergence commencing at ~125–120 Ma, during reversal in tangential motion of the Pacific plate. After ~120 Ma, nearly head-on subduction involving minor dextral transpression gave rise to voluminous continent-building juvenile and recycled magmas of the Sierran arc, providing the erosional debris to the Great Valley fore arc and Franciscan trench
Bootstrap-Based Improvements for Inference with Clustered Errors
Microeconometrics researchers have increasingly realized the essential need to account for any within-group dependence in estimating standard errors of regression parameter estimates. The typical preferred solution is to calculate cluster-robust or sandwich standard errors that permit quite general heteroskedasticity and within-cluster error correlation, but presume that the number of clusters is large. In applications with few (5-30) clusters, standard asymptotic tests can over-reject considerably. We investigate more accurate inference using cluster bootstrap-t procedures that provide asymptotic refinement. These procedures are evaluated using Monte Carlos, including the much-cited differences-in-differences example of Bertrand, Mullainathan and Duflo (2004). In situations where standard methods lead to rejection rates in excess of ten percent (or
more) for tests of nominal size 0.05, our methods can reduce this to five percent. In principle a pairs cluster bootstrap should work well, but in practice a Wild cluster bootstrap performs better.clustered errors; random effects; cluster robust; sandwich; bootstrap; bootstrap-t; clustered bootstrap; pairs bootstrap; wild bootstrap.
On the Snow Line in Dusty Protoplanetary Disks
The snow line, in Hayashi's (1981) model, is where the temperature of a black
body that absorbed direct sunlight and re-radiated as much as it absorbed,
would be 170~K. It is usually assumed that the cores of the giant planets,
e.g., Jupiter, form beyond the snow line. Since Hayashi, there have been a
series of more detailed models of the absorption by dust of the stellar
radiation, and of accretional heating, which alter the location of the snow
line. We have attempted a "self-consistent" model of a T Tauri disk in the
sense that we used dust properties and calculated surface temperatures that
matched observed disks. We then calculated the midplane temperature for those
disks, with no accretional heating or with small (<10^-8) accretion rates. Our
models bring the snow line in to the neighbourhood of 1 AU; not far enough to
explain the close planetary companions to other stars, but much closer than in
recent starting lines for orbit migration scenarios.Comment: 9 pages, 1 figure, to appear in ApJ,528,200
Bootstrap-Based Improvements for Inference with Clustered Errors
Researchers have increasingly realized the need to account for within-group dependence in estimating standard errors of regression parameter estimates. The usual solution is to calculate cluster-robust standard errors that permit heteroskedasticity and within-cluster error correlation, but presume that the number of clusters is large. Standard asymptotic tests can over-reject, however, with few (5-30) clusters. We investigate inference using cluster bootstrap-t procedures that provide asymptotic refinement. These procedures are evaluated using Monte Carlos, including the example of Bertrand, Duflo and Mullainathan (2004). Rejection rates of ten percent using standard methods can be reduced to the nominal size of five percent using our methods.
Robust Inference with Multi-way Clustering
In this paper we propose a new variance estimator for OLS as well as for nonlinear estimators such as logit, probit and GMM, that provcides cluster-robust inference when there is two-way or multi-way clustering that is non-nested. The variance estimator extends the standard cluster-robust variance estimator or sandwich estimator for one-way clustering (e.g. Liang and Zeger (1986), Arellano (1987)) and relies on similar relatively weak distributional assumptions. Our method is easily implemented in statistical packages, such as Stata and SAS, that already offer cluster-robust standard errors when there is one-way clustering. The method is demonstrated by a Monte Carlo analysis for a two-way random effects model; a Monte Carlo analysis of a placebo law that extends the state-year effects example of Bertrand et al. (2004) to two dimensions; and by application to two studies in the empirical public/labor literature where two-way clustering is present.
WASP-1: A lithium- and metal-rich star with an oversized planet
In this paper we present our results of a comprehensive spectroscopicanalysis
of WASP-1, the host star to the exoplanet WASP-1b. We derive T_eff = 6110 +/-
45 K, log g = 4.28 +/- 0.15, and [M/H] = 0.23 +/- 0.08, and also a high
abundance of lithium, log n(Li) = 2.91 +/- 0.05. These parameters suggests an
age for the system of 1-3 Gyr and a stellar mass of 1.25-1.35 M_sun. This means
that WASP-1 has properties very similar to those of HD 149026, the host star
for the highest density planet yet detected. Moreover, their planets orbit at
comparable distances and receive comparable irradiating fluxes from their host
stars. However, despite the similarity of WASP-1 with HD 149026, their planets
have strongly different densities. This suggests that gas-giant planet density
is not a simple function of host-star metallicity or of radiation environment
at ages of ~2 Gyr.Comment: Accepted for publication in MNRAS. 6 pages, 4 figure
Warm dust in the terrestrial planet zone of a sun-like Pleiad: collisions between planetary embryos?
Only a few solar-type main sequence stars are known to be orbited by warm
dust particles; the most extreme is the G0 field star BD+20 307 that emits ~4%
of its energy at mid-infrared wavelengths. We report the identification of a
similarly dusty star HD 23514, an F6-type member of the Pleiades cluster. A
strong mid-IR silicate emission feature indicates the presence of small warm
dust particles, but with the primary flux density peak at the non-standard
wavelength of ~9 micron. The existence of so much dust within an AU or so of
these stars is not easily accounted for given the very brief lifetime in orbit
of small particles. The apparent absence of very hot (>~1000 K) dust at both
stars suggests the possible presence of a planet closer to the stars than the
dust. The observed frequency of the BD+20 307/HD 23514 phenomenon indicates
that the mass equivalent of Earth's Moon must be converted, via collisions of
massive bodies, to tiny dust particles that find their way to the terrestrial
planet zone during the first few hundred million years of the life of many
(most?) sun-like stars. Identification of these two dusty systems among
youthful nearby solar-type stars suggests that terrestrial planet formation is
common.Comment: ApJ in press, 19 pages including 3 figures and 2 tables, minor
changes to the tables and figure
Surface differential rotation and prominences of the Lupus post T Tauri star RX J1508.6-4423
We present in this paper a spectroscopic monitoring of the Lupus post T Tauri star RX J1508.6-4423 carried out at two closely separated epochs (1998 May 06 and 10) with the UCL Echelle Spectrograph on the 3.9-m Anglo-Australian Telescope. Applying least-squares convolution and maximum entropy image reconstruction techniques to our sets of spectra, we demonstrate that this star features on its surface a large cool polar cap with several appendages extending to lower latitudes, as well as one spot close to the equator. The images reconstructed at both epochs are in good overall agreement, except for a photospheric shear that we interpret in terms of latitudinal differential rotation. Given the spot distribution at the epoch of our observations, differential rotation could only be investigated between latitudes 15° and 60°. We find in particular that the observed differential rotation is compatible with a solar-like law (i.e., with rotation rate decreasing towards high latitudes proportionally to sin 2l, where l denotes the latitude) in this particular latitude range. Assuming that such a law can be extrapolated to all latitudes, we find that the equator of RX J1508.6-4423 does one more rotational cycle than the pole every 50 ±10 d, implying a photospheric shear 2 to 3 times stronger than that of the Sun. We also discover that the Hα emission profile of RX J1508.6-4423 is most of the time double-peaked and strongly modulated with the rotation period of the star. We interpret this rotationally modulated emission as being caused by a dense and complex prominence system, the circumstellar distribution of which is obtained through maximum entropy Doppler tomography. These maps show in particular that prominences form a complete and inhomogeneous ring around the star, precisely at the corotation radius. We use the total Hα and Hβ emission flux to estimate that the mass of the whole prominence system is about 10 20g. From our observation that the whole cloud system surrounding the star is regenerated in less than 4 d, we conclude that the braking time-scale of RX J1508.6-4423 is shorter than 1 Gyr, and that prominence expulsion is thus likely to contribute significantly to the rotational spindown of young low-mass stars
Picoliter-volume inkjet printing into planar microdevice reservoirs for low-waste, high-capacity drug loading.
Oral delivery of therapeutics is the preferred route for systemic drug administration due to ease of access and improved patient compliance. However, many therapeutics suffer from low oral bioavailability due to low pH and enzymatic conditions, poor cellular permeability, and low residence time. Microfabrication techniques have been used to create planar, asymmetric microdevices for oral drug delivery to address these limitations. The geometry of these microdevices facilitates prolonged drug exposure with unidirectional release of drug toward gastrointestinal epithelium. While these devices have significantly enhanced drug permeability in vitro and in vivo, loading drug into the micron-scale reservoirs of the devices in a low-waste, high-capacity manner remains challenging. Here, we use picoliter-volume inkjet printing to load topotecan and insulin into planar microdevices efficiently. Following a simple surface functionalization step, drug solution can be spotted into the microdevice reservoir. We show that relatively high capacities of both topotecan and insulin can be loaded into microdevices in a rapid, automated process with little to no drug waste
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