中国大型国有企業の再編と経営システム改革 : 中国石油天然ガス集団の事例を中心として

departmental bulletin pape

小学校高学年を対象とした体育授業におけるハードリング変容<教育科学>

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Observation of B→K*ℓ+ℓ-

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日中における自動車産業の国際協力

2009-032000年以来、中国における自動車産業がすさまじいスピードで発展してきた。その背景では、中国経済の高度成長に従って国民生活水準も高くなり富裕層と中間層が急速に増え、乗用車に対する需要も増加させた。さらに中国政府は自動車産業を柱産業として発展させる方針もありこれからさらなる発展を見せるだろう。このような発展スピードではあと40年ないし50年、中国には自動車保有台数5、6億台になるのではないか。そうなると、もたらしてくるエネルギー問題と環境問題は想像し切れないほど深刻だろう。最悪な局面を回避するためには日中両国の協力が最適な選択なのではないかと考えられる。departmental bulletin pape

Forskolin enhances PMA-dependent CD86 expression while inhibiting CD11b up-regulation and CaMKKα nuclear localization.

<p>(A and B) U937 cells were pretreated with or without 30 µM forskolin for 1 h prior to activation with 100 nM PMA for 48 h, as indicated. Surface expression of CD11b and CD86 was quantified by flow cytometry using FITC-conjugated CD11b and PE-conjugated CD86 antibodies. Results significantly different from PMA at α = 0.05 are indicated by (*). Results represent an average of three independent experiments±SEM. (C) Cells were treated as in panel A and CaMKKα was quantified by Western analysis of nuclear lysates. Results are representative of three independent experiments. (D) U937 cells were treated as in panel A and ERK1/2 phosphorylation (ERK-p) and mass (ERK) were measured by Western analysis in whole cell lysates. Results are representative of three independent experiments.</p

大山山麓の鹹味ある鉱物について

departmental bulletin pape

Phagocytosis and fluid-phase endocytosis are not increased in PerMΦs from <i>db/db</i> mice.

<p><i>A</i>, <i>Db</i>/+and <i>db/db</i> mice were IP administered 0.21 or 2.6 µm latex microspheres (beads) at 5×10⁹ or 5×10⁷ beads/ml, respectively. Following a 4 h <i>in vivo</i> incubation period, PerMΦs were collected and microsphere uptake was measured by flow cytometry. <i>B, Db</i>/+and <i>db/db</i> mice were IP administered 0.25 mg/ml FITC-dextran. Following a 4 h <i>in vivo</i> incubation period, PerMΦs were collected and dextran uptake was measured by flow cytometry. Results for <i>A</i> and <i>B</i> represent the average of three independent experiments±SEM.</p

Inhibition of CaMKKα by siRNA enhances PMA-dependent up-regulation of CD86 but decreases CD11b expression.

<p>(A and B) Cells were treated with 0.25 µg of either CaMKKα siRNA or scramble siRNA control prior to stimulation with 100 nM PMA for 48 h. Surface expression of CD11b and CD86 was quantified by flow cytometry. Results significantly different from PMA at α = 0.05 are indicated by (*). Results represent an average of three independent experiments±SEM. (C) Cells were treated as in A and CaMKKα protein expression was quantified by intracellular flow. Results significantly different from control at α = 0.05 are indicated by (*). Results represent an average of three independent experiments±SEM.</p

<i>Db/db</i> mice have elevated blood glucose and serum insulin levels.

<p>Fasting blood glucose (FBG), random blood glucose (RBG), fasting serum insulin (FSI), and random serum insulin (RSI). Results represent the average of n = 5 mice±SEM. *: p<0.05.</p

The PKC inhibitor Bisindolylmaleimide inhibits PMA-dependent upregulation of CD86/CD11b expression.

<p>(A & B) U937 cells were pretreated with or without 1 µM bisindolylmaleimide for 15 min prior to activation with 100 nM PMA for 48 h, as indicated. Surface expression of CD11b and CD86 was quantified by flow cytometry using FITC-conjugated CD11b and PE-conjugated CD86 antibodies. Results significantly different from PMA at α = 0.05 are indicated by (*). Results represent an average of three independent experiments±SEM.</p