1,367 research outputs found

    Rapid learning of visual ensembles

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    open3siWe recently demonstrated that observers are capable of encoding not only summary statistics, such as mean and variance of stimulus ensembles, but also the shape of the ensembles. Here, for the first time, we show the learning dynamics of this process, investigate the possible priors for the distribution shape, and demonstrate that observers are able to learn more complex distributions, such as bimodal ones. We used speeding and slowing of response times between trials (intertrial priming) in visual search for an oddly oriented line to assess internal models of distractor distributions. Experiment 1 demonstrates that two repetitions are sufficient for enabling learning of the shape of uniform distractor distributions. In Experiment 2, we compared Gaussian and uniform distractor distributions, finding that following only two repetitions Gaussian distributions are represented differently than uniform ones. Experiment 3 further showed that when distractor distributions are bimodal (with a 30° distance between two uniform intervals), observers initially treat them as uniform, and only with further repetitions do they begin to treat the distributions as bimodal. In sum, observers do not have strong initial priors for distribution shapes and quickly learn simple ones but have the ability to adjust their representations to more complex feature distributions as information accumulates with further repetitions of the same distractor distribution.openChetverikov, Andrey; Campana, Gianluca; Kristjánsson, ÁrniChetverikov, Andrey; Campana, Gianluca; Kristjánsson, Árn

    Genome-Wide Association Study in Mexican Holstein Cattle Reveals Novel Quantitative Trait Loci Regions and Confirms Mapped Loci for Resistance to Bovine Tuberculosis

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    Bovine tuberculosis (bTB) is a disease of cattle that represents a risk to public health and causes severe economic losses to the livestock industry. Recently, genetic studies, like genome-wide association studies (GWAS) have greatly improved the investigation of complex diseases identifying thousands of disease-associated genomic variants. Here, we present evidence of genetic variants associated with resistance to TB in Mexican dairy cattle using a case-control approach with a selective DNA pooling experimental design. A total of 154 QTLRs (quantitative trait loci regions) at 10% PFP (proportion of false positives), 42 at 5% PFP and 5 at 1% PFP have been identified, which harbored 172 annotated genes. On BTA13, five new QTLRs were identified in the MACROD2 and KIF16B genes, supporting their involvement in resistance to bTB. Six QTLRs harbor seven annotated genes that have been previously reported as involved in immune response against Mycobacterium spp: BTA (Bos taurus autosome) 1 (CD80), BTA3 (CTSS), BTA 3 (FCGR1A), BTA 23 (HFE), BTA 25 (IL21R), and BTA 29 (ANO9 and SIGIRR). We identified novel QTLRs harboring genes involved in Mycobacterium spp. immune response. This is a first screening for resistance to TB infection on Mexican dairy cattle based on a dense SNP (Single Nucleotide Polymorphism) chip

    Evolutionary Computation Applied to Urban Traffic Optimization

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    At the present time, many sings seem to indicate that we live a global energy and environmental crisis. The scientific community argues that the global warming process is, at least in some degree, a consequence of modern societies unsustainable development. A key area in that situation is the citizens mobility. World economies seem to require fast and efficient transportation infrastructures for a significant fraction of the population. The non-stopping overload process that traffic networks are suffering calls for new solutions. In the vast majority of cases it is not viable to extend that infrastructures due to costs, lack of available space, and environmental impacts. Thus, traffic departments all around the world are very interested in optimizing the existing infrastructures to obtain the very best service they can provide. In the last decade many initiatives have been developed to give the traffic network new management facilities for its better exploitation. They are grouped in the so called Intelligent Transportation Systems. Examples of these approaches are the Advanced Traveler Information Systems (ATIS) and Advanced Traffic Management Systems (ATMS). Most of them provide drivers or traffic engineers the current traffic real/simulated situation or traffic forecasts. They may even suggest actions to improve the traffic flow. To do so, researchers have done a lot of work improving traffic simulations, specially through the development of accurate microscopic simulators. In the last decades the application of that family of simulators was restricted to small test cases due to its high computing requirements. Currently, the availability of cheap faster computers has changed this situation. Some famous microsimulators are MITSIM(Yang, Q., 1997), INTEGRATION (Rakha, H., et al., 1998), AIMSUN2 (Barcelo, J., et al., 1996), TRANSIMS (Nagel, K. & Barrett, C., 1997), etc. They will be briefly explained in the following section. Although traffic research is mainly targeted at obtaining accurate simulations there are few groups focused at the optimization or improvement of traffic in an automatic manner â not dependent on traffic engineers experience and âartâ. O pe n A cc es s D at ab as e w w w .ite ch on lin e. co
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