有機相／水相界面における新規な相転移および臨界現象についての研究

プロジェクト番号 : A12-93一般研究 : 基礎研究textapplication/pdfresearch repor

Influence of Mass Media on the Issues of a Multi-Cultural Society: Analysis on the Experimental Classes Discussing Interdisciplinary Topics

text紀要論文 / Departmental Bulletin Paperdepartmental bulletin pape

Measurement of inclusive production of neutral pions from Υ(4S) decays

journal articl

Is there a place for human fetal-derived stem cells for cell replacement therapy in Huntington's disease?

Huntington's disease (HD) is a neurodegenerative disease that offers an excellent paradigm for cell replacement therapy because of the associated relatively focal cell loss in the striatum. The predominant cells lost in this condition are striatal medium spiny neurons (MSNs). Transplantation of developing MSNs taken from the fetal brain has provided proof of concept that donor MSNs can survive, integrate and bring about a degree of functional recovery in both pre-clinical studies and in a limited number of clinical trials. The scarcity of human fetal tissue, and the logistics of coordinating collection and dissection of tissue with neurosurgical procedures makes the use of fetal tissue for this purpose both complex and limiting. Alternative donor cell sources which are expandable in culture prior to transplantation are currently being sought. Two potential donor cell sources which have received most attention recently are embryonic stem (ES) cells and adult induced pluripotent stem (iPS) cells, both of which can be directed to MSN-like fates, although achieving a genuine MSN fate has proven to be difficult. All potential donor sources have challenges in terms of their clinical application for regenerative medicine, and thus it is important to continue exploring a wide variety of expandable cells. In this review we discuss two less well-reported potential donor cell sources; embryonic germ (EG) cells and fetal neural precursors (FNPs), both are which are fetal-derived and have some properties that could make them useful for regenerative medicine applications.</p

上・下流境界条件の変化による直線砂礫流路の側岸侵食を伴う河床低下に関する研究

堰の撤去や河川改修といった境界条件の変化によって河床は大きく変化する。本研究では、側岸侵食と河床低下が同時に生じる場合の直線砂礫河道の変化過程を、水理実験と平面2次元の河床変動解析を用いて検討したものである。水理実験の結果、河床低下が流路拡幅に大きく影響されることがわかった。またこのような河床低下過程は、流路拡幅の効果を取り込むことにより、従来から用いられている拡散型の河床変動として近似的に取り扱えることを明らかにした。さらに、これらの状況をより詳しく考察するため、側岸の侵食や崩落に伴う砂礫河岸拡幅過程を再現できる平面に２次元河床変動解析モデルを構築した。このモデルによる計算結果と実験結果との適合性は良好であった。In this research, horizontal bed-topography due to dam-construction or large-scale river improvement was studied as simplified processes of bed degradation with side-bank erosion, through flume experiments and numerical analysis. Firstly, we investigated the interaction between widening of gravel channel and degradation of channel bed with hydraulic model experiment. As a result, it was understood that the conventional diffusion model of the degradation with a modified diffusion coefficient could be applied even if the channel widening accompanies. Secondary, we constructed the 2-D numerical simulation model taking account of the widening process with bank erosion in a gravel channel, and examined the application of the numerical model by using the experimental data. The numerical analysis could explain the flume experiments well.journal articl

Study on Shape Judgment of Vegetables and Fruits of Long Size By Using Neural Network

departmental bulletin pape