16,814 research outputs found

    CineAfriq@BU presents: La Pirogue (movie poster)

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    This movie poster is designed to let the BU community know about a CineAfriq@BU screening of the Moussa Touré film "La Pirogue.

    Reforma en el mundo ĂĄrabe

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    Texto de la conferencia pronunciada por Amre Moussa, Secretario General de la Liga Árabe, el 10 de noviembre de 2004 en el Casino de Madrid, organizada por el Real Instituto Elcano

    The Effect of DNA Methylation on TP73 Expression in Tumorgenesis

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    Abstract: The Effect of DNA Methylation on TP73 Expression in Tumorgenesis Nujuma Moussa, Zhixing Yao, Zaki A. Sherif Department of Biochemistry & Molecular Biology, Howard University College of Medicine TP73 is a member of the TP53 family of proteins that acts as a transcription factor to help regulate cellular distress. This tumor protein may play a dual role as a tumor suppressor and tumor promoter. The TP73 gene is mapped to chromosome 1p36, a frequently deleted region in neuroblastoma and other types of tumors. While mutations in the TP53 gene are commonly known to cause noxious cancers, 30% of cancers result from the overexpression of TP73. In our lab, we examined the role of TP73 in the formation of neuroblastoma, a type of cancer that begins in the nerve tissue atop the adrenal gland of kidneys in children. Normal fibroblast cell lines (HS27) and tumor kidney cells (IMR32 and SK-N-SH) were grown in their respective growth media. DNA and RNA of both cell types were extracted using standard procedures. RNA expression was analyzed by RT-PCR and DNA methylation was analyzed by bisulfite sequencing. The expressions of TP73 gene and its protein were analyzed by gel electrophoresis and immunohistochemistry respectively. We found that the TP73 gene was expressed in all of the neuroblastoma cells, but there was no evidence of its expression in the normal cell lines. Subsequent methylation studies revealed that TP73 was expressed in neuroblastoma cells but not in non-cancerous cells due to silencing by DNA methylation. In conclusion, the absence of TP73 in normal cells is in part due to DNA methylation implying that TP73 plays a role in the promotion and/or progression of carcinogenesis.https://scholarscompass.vcu.edu/uresposters/1288/thumbnail.jp

    Moussa v. Atty Gen USA

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    Agenc

    How the rising cost of essentials has tightened the squeeze on family incomes

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    New research suggests that benefit cuts, harsher benefit rules and the rising costs of essentials are all hitting poor families in the UK at the same time. This can only serve to reinforce the urgency of making sure people on low incomes are protected, writes Moussa Haddad

    Geological And Geotechnical Characterization Of The Beni Moussa Perimeter In The Tadla Plain(Morocco)

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    The Beni Moussa perimeter in the plain of Tadla is located in the Beni Mellal - Khenifra region characterized by the diversity of its relief where the mountain meets the plain through the foothills. Bibliographic studies raise the dominance of limestone formations in the Atlas ranges of this region, and the piedmont accumulates alluvium deposited by rivers, while the plain is filled with mio-plio-quaternary deposits. A series of seven drill holes of various depths, supplemented by pressuremeter measurements every 1.50m of depth using the Menard pressuremeter, was carried out on sites scattered around the perimeter of the Beni Moussa in the plain of Tadla, to validate at first the bibliographic geological models, then to appreciate the bearing capacity of the lithologies revealed. The lithological sections thus revealed an alternation of alluvial deposits, clays and clay loams, deposited on calcareous formations, resulting from the dolomitic and calcareous mountainous debris mobilized following the seasonal temperature’s variation of the region. Moreover, the measured pressurometric ranges characterize a generally high bearing capacity, and reflect the generalized overconsolidation of the facies and soils encountered in the Beni Moussa area, except for the Middle Pleistocene formations, which are mainly characterized by channeled conglomeratic deposits.This study’s datathus reflect a good bearing capacity of the ground formations, capable of supporting the superstructures founded in this perimeter

    Title To Certain Lands

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    Mem. of C. Moussa. 14 Aug. SMD 14, 53-1. v1, 4p. [3145] On title to land in Minnesota; set apart for half-breed Sioux or Dakotas under the treaty of 15 July 1830

    Guinea vor den PrĂ€sidentschaftswahlen am 27. Juni 2010 : Ein BĂŒrgerkrieg abgewendet?

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    Nach dem MilitÀrputsch vom 23. Dezember 2008 eskalierte in Guinea die Gewalt. Trauriger Höhepunkt was das Massaker vom 28. September 2009, als MilitÀrs Proteste der zivilen und politischen Opposition in Conakry blutig niederschlugen. Und das Attentat auf den MilitÀrmachthaber, Hauptmann Moussa Dadis Camara, der am 3. Dezember 2009 schwer verletzt wurde, reiht sich in die Gewaltspirale ein
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