Design and Implementation of Community Policing Work Management System of Wenzhou Based on .NET

随着现代警务机制与科学技术的发展，结合公安部对基层警务信息化的发展要求，科技强警成为提升公安工作效能的一条必经之路。社区警务工作是基层公安工作的重要一环，在夯实基础、强化管控、强化打击、优化服务等方面都有着重要意义，因此实现社区内警务管理智能化，是提升现代公安工作水平的重要一环。本系统结合实际的警务工作，对社区内流动人口和常住人口进行信息化管理，以及对特殊场所的监视管理。系统结合警务工作人员的工作习惯，对系统的操作进行优化，尽量让警务工作人员操作方便。同时，该系统会将后台的数据显示在地图上，可以让人更直观的了解社区内的人、房的信息，通过海量信息的调用及分析研判，服务社区民警开展人、房等基础信息...With the development of modern policing mechanism and science and technology, combined with the development requirements of the Ministry of Basic Police information technology, public security work to enhance the effectiveness of police training and technology to become one pass. Community policing is a grass-roots public security work an important part of the solid foundation, strengthen the mana...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323177

股权分置的路径依赖分析

以国有股减持和非流通股全流通为目的的股权分置改革作为上市公司股权制度的制度变迁,存在着路径依赖问题。通过对股权分置的历史沿革和现阶段股权分置改革中出现的问题的分析,提出国家要克服自身的有限理性,降低对减持国有股的收益预期,确立对价参照标准,以明确投资者心理预期,减少制度变迁成本,有利于中国资本市场的长期稳定发展。国家社科基金(04BJC026);; 教育部文科研究基地重大项目(05JJD790026);; 福建省社科基金(2003003E

电子商务与展览业联手──新世纪的完美组合

随着网络经济的发展，电子商务在新经济舞台上扮演着越来越重要的角色，它必将对我国的朝阳产业——展览业产生重大影响。电子商务就是信息流的数字化、电子化，它最拿手的就是对信息和数据的快速传递、交换和处理，促进交流，增加信息透明度，降低交易成本，而展览在其本质意义上说首要功能是传播信息。因此，电子商务与展览业一拍即合，展览业成为电子商务可大显身手的舞台，从而加速我国展览业与国际接轨

Degradation performance of the digital coralline hydroxyapatite artificial bone scaffold in vitro

背景:前期实验成功制备了数字化珊瑚羟基磷灰石人工骨支架材料,并已证实其具有良好的理化性能和生物相容性。目的:评价数字化珊瑚羟基磷灰石人工骨的体外降解性能。方法:将珊瑚羟基磷灰石与左旋-聚乳酸分别以3∶1和4∶1的质量比混合,制备数字化珊瑚羟基磷灰石人工骨支架材料试件。将两种数字化人工骨支架材料、珊瑚羟基磷灰石及左旋-聚乳酸分别置于初始p H值为7.4的50 m L模拟体液中,在37℃恒温箱中降解16周,动态观察溶液p H值、钙及磷离子浓度,以及材料降解率、抗压强度及微观结构变化。结果与结论:降解16周时,两种数字化人工骨组的p H值维持在7.34-7.36,高于左旋-聚乳酸组(P3∶1数字化人工骨组>左旋-聚乳酸组>4∶1数字化人工骨组;两种数字化人工骨微孔结构增多,孔隙率升高,孔径增大,说明数字化珊瑚羟基磷灰石人工骨支架具有良好的降解性能。BACKGROUND: We have successfully prepared the digital coralline hydroxyapatite artificial bone scaffold in previous experiments, and it has good physicochemical properties and biocompatibility. OBJECTIVE: To evaluate the in vitro degradation performance of the digital coralline hydroxyapatite artificial bone. METHODS: We used the mixtures of coralline hydroxyapatite and L-polylactic acid at the mass ratio of 3:1 and 4:1 as raw materials to prepare the digital coralline hydroxyapatite artificial bone scafflold specimens, and then they were immersed in the 50 m L stimulated body fluid with the initial p H value of 7.4 in an incubator at 37 ℃ for degradation. After 16 weeks of degradation, the p H value, calcium and phosphate ion concentration, degradation rate, compressive strength and changes of microstructure were dynamically observed. RESULTS AND CONCLUSION: At the 16 th weeks of degradation, the p H values in the two kinds of digital artificial bone groups maintained at 7.34-7.36, which were higher than that in the L-polylactic acid group(P 3:1 digital artificial bone group > L-polylactic acid group > 4:1 digital artificial bone group. The cellular structure, porosity and pore size in the two kinds of digital artificial bone groups were all increased. These results show that the prepared digital coralline hydroxyapatite artificial bone scaffold has good degradation propertyies.福建省教育厅科技项目(JA12416);; 福建省自然科学基金青年创新项目(2013D013);; 漳州职业技术学院院级科研项目(ZZY1204)~

Effects of Jiangu Granules on the proliferation of osteoblasts through G_1/S phase cell-cycle regulated proteins

目的观察健骨颗粒对成骨细胞G_1/S期调控的影响,探讨健骨颗粒促进成骨细胞增殖的作用机制。方法制备健骨颗粒血清组、模型血清组和雌二醇血清组。采用酶消化法培养SD大鼠成骨细胞,健骨颗粒含药血清干预,以模型血清和雌二醇血清为对照。运用流式细胞术检测成骨细胞增殖周期,荧光定量PCR法检测成骨细胞G_1/S期调控蛋白Cyclin E、CDK2、p21和转录因子E2F-1 m RNA的表达。结果 15%的雌二醇血清与健骨颗粒血清干预48 h,成骨细胞增殖速度均明显快于模型血清组(P<0.01);G_0/G_1期成骨细胞比例明显降低(P<0.01),S期、G_2/M期细胞比例及增殖指数则明显高于模型血清组(P<0.01);与模型血清组比较,雌二醇血清组与健骨颗粒血清组能提高成骨细胞Cyclin E、CDK2及转录因子E2F-1 m RNA的表达(P<0.01),而降低p21的表达(P<0.01)。结论健骨颗粒通过调节成骨细胞G_1/S期调控机制,推进成骨细胞顺利通过G_1/S检测点,促进成骨细胞增殖。Objective To observe the effects of Jiangu Granules on the G_1/S phase cell-cycle regulated proteins of osteoblasts, so as to reveal the mechanism of Jiangu Granules in promoting osteoblasts proliferation. Methods The Jiangu Granules-serum group, model-serum group and estradiol-serum group were prepared. Osteoblasts of SD rats were cultivated by enzymatic digestion and intervened with Jiangu Granules-serum, model-serum and estradiol-serum(as control) respectively. The cell cycles were analyzed by flow cytometry, while the fluorescence quantitative PCR was applied to measure cyclin E, CDK2, p21 and E2F-1 m RNA. Results The cell proliferation rates of osteoblasts intervened with estradiol serum and Jiangu Granules-serum for 48 hours were faster than that with the same concentration model-serum(P < 0.01). Compared with the model-serum group, the proportion of osteoblasts in the G_0/G_1 phase were significantly reduced after intervention with 15% of estradiol serum and Jiangu Granules-serum for 48 hours(P < 0.01),while the proportion of cells in S phase, G_2/M phase and proliferation index was much higher(P < 0.01). The expression of cycling E, CDK 2 and transcription factor E2F-1 m RNA of osteoblasts in the Jiangu Granules-serum group and the estradiol-serum group was higher than that of model-serum group(P < 0.01), while the expression of p21 m RNA was lower than the model-serum group(P < 0.01). Conclusion Jiangu Granules-serum can adjust the G_1/S phase cellcycle regulated mechanism in osteoblast, so as to push the cells passing G_1/S checkpoint and accelerate the proliferation of osteoblast.国家自然科学基金资助项目(81473706

电烤盘温度场的有限元分析

【中文文摘】本文介绍了运用有限元法,对电烤盘的热传导进行仿真分析。运用MSC.MARC非线性有限元软件,模拟了电烤盘加热过程和温度场分布,为产品结构的优化改进提供依据

Advance of stir bar sorptive extraction

作为一种新型的环境友好型样品前处理技术,搅拌棒固相萃取(SbSE)集萃取、净化和富集为一体,已经在环境监测、食品安全和生物分析等领域进行了广泛应用。本文结合作者所在研究小组的研究工作,对近几年来SbSE技术的发展进行综述,重点阐述了各种新涂层的研究和应用,同时就SbSE发展方向提出了展望。Stir bar sorptive extraction(SBSE) is an environmentally-friendly technology of sample preparation which combines extraction,cleanup and enrichment together,and it has been developed rapidly and widely applied to the trace enrichment of various target analytes in environmental,food and biological samples.Based on our research,the advance of SBSE,especially,the development of new coatings,are review ed.At the same time,the possible development orientations of SBSE are discussed.国家自然科学基金项目(21077085);福建省自然科学基金项目(2010J01047

纳米酶在疾病治疗中的最新进展

纳米酶是具有酶催化活性的纳米材料,对比天然酶,纳米酶具有价格便宜、制备工艺简单、稳定性好、循环利用率高等优势.早期的纳米酶研究主要集中在检测方面,包括检测离子、小分子、核酸、蛋白质、癌细胞等,随着对纳米酶的深入了解,研究人员发现纳米酶在疾病治疗领域也具有巨大的应用前景.本论文将介绍纳米酶在细菌感染、炎症、癌症、神经退行性疾病等治疗领域的最新研究进展

双压电驱动高频喷射点胶阀的设计与实验

为了满足电子封装产业对胶体高速、微量分配的需求,设计了一种基于圆弧柔性铰链放大机构的双压电陶瓷驱动喷射点胶阀。首先,利用有限元分析软件对放大机构输出位移和模态进行了计算与分析。针对其高频需求,讨论了结构参数对其影响因素。基于微元法并结合喷嘴内胶体动力学分析,建立了喷嘴内胶体喷射的流体力学模型。结合阀杆与阀座配合的仿真模型,利用FLOW-3D的流固耦合仿真,揭示了喷射点胶时胶点的成型过程。在此基础上探究了胶体喷射时喷嘴处压力的变化与流速的关系,为点胶阀参数的控制和优化奠定了基础。最后,搭建了喷射系统实验平台,选用黏度为180cps的胶体进行点胶性能测试,得出了供料压力和驱动方波频率对胶点尺寸的影响规律。实验结果显示,在供料压力为6bar,驱动方波幅值频率360Hz等参数下,获得胶点最小直径为525μm。同时,在380～400Hz的频率区间内进行高频喷射实验,能够获得均匀微小的圆形胶点。实验结果验证了该圆弧柔性铰链放大机构的双压电驱动点胶阀的高频、微量喷射性能,为压电高频喷射点胶的应用和研究提供了参考。深圳市科技计划资助项目(No.JCYJ20170818141912229);;\n航空科学基金资助项目(No.20160868004

猪胰铁蛋白释放铁和磷酸盐的动力学特性

猪胰铁蛋白(p ig pancreas ferritin,PPF)铁核由179 phosphate/PPF和1698 Fe3+/PPF组成,平均磷铁比值为1∶9.5.PFF铁核表层由较高的磷铁比组成.选用电子光谱技术研究PPF释放铁和磷酸盐全过程,发现PPF以两种不同速率途径释放铁与磷酸盐.在弱酸条件下,PPF释放铁的速率明显高于在弱碱条件下的速率,证实PPF蛋白壳的柔性调节能力强弱是控制释放铁和磷酸盐速率的重要因素之一