LTE230-Based Power Wireless Private Network Applications and Implementation on Changdao

针对山东长岛特有的复杂海岛环境、交通不便、通信网络分散等问题,提出了建设LTE230系统的发展方案。通过对LTE230系统的优势特点进行分析,着重介绍了多个智能化的应用,该系统在智能电网中发挥了不可替代的作用,其良好的覆盖效果和通信能力可满足当地的应用需求。In Shandong province, targeting Changdao's unique complex island environment, traffi c inconvenience, and the dispersion issues of communication network, the paper proposed the construction LTE230 system development program. Through the analysis of the advantages of LTE230 system characteristics, the paper emphatically introduced multiple intelligent applications. The system played an irreplaceable role in smart grid, its good coverage and communication ability met the local application demand.烟台科技项目(5206051400K9

甲壳素类液晶高分子研究——低分子量壳聚糖溶致液晶性及分子量对液晶临界浓度的影响

研究了两种用酶降解法得到的低分子量壳聚糖样品(CS1和CS2)的溶致液晶性.用GPC并辅以质谱法确定了两样品的数均相对分子质量为622和2311 g/mol.在相对分子质量低至622的低分子量壳聚糖(相当于四糖)水溶液中仍发现了溶致液晶现象,并确定出相对分子质量为622和2311的低分子量壳聚糖液晶临界浓度为73%和36%(W/W%),这些结果与已报道的中、高分子量壳聚糖液晶临界浓度随分子量升高而降低的基本规律是一致的.实验结果与经典的KS理论预测值不符,因为低分子量壳聚糖的相对分子质量超过了KS理论对高分子临界浓度的预测范围

Study on the free radical scavenging activity of polyphenolic compounds by on-line high-flux screening method

目的:构建植物化学物在线清除自由基活性高通量筛选技术,创建植物化学物抗氧化活性研究新方法。方法:以附带2个检测器的高效液相色谱(HPlC)装置和流动注射技术为手段,引入二苯基三硝基苯肼(dPPH)有机自由基分别与经HPlC分离的植物化学物发生在线清除反应,优化流速、反应管尺寸等条件,比较反应前后dPPH吸收信号的变化。结果:确定和验证了两类植物多酚化学物茶多酚和丹酚酸在线清除自由基活性HPlC-dPPH表征方法。反应环聚醚醚酮(PEEk)盘管规格为长10M、内径0.254MM,dPPH·浓度为1.0x10-5MOl/l,流速为0.7~0.8Ml/MIn。结论:HPlC-dPPH流动注射在线表征技术能够实现对多组分植物化学物抗氧化能力的高通量筛选。Objective:To construct a high-flux screening procedure by on-line free radical scavenging activity method of phyto- chemicals, and create a new evaluation system of antioxidant activity of natural plant materials.Methods:A HPLC system with two detectors and flow injection techniques was employed.An organic free radicals DPPH was induced on-line HPLC-DPPH and reaction with the single phytochemical components isolated by HPLC.To optimize reactive conditions including flow rate and the size of reaction coil, and detect the DPPH signals before and after reaction.Results:A new on-line HPLC-DPPH method was established for a high-flux screening of several free radical scavenging components exampled as Tea polyphenols and Salvianolic acids.The reaction coil of PEEK was 10 m length and inner diameter 0.254 mm, the concentration and flow velocity of DPPH was 1.0 × 10-5mol/L and 0.7～0.8 ml/ min, respectively.Conclusion:The PHLC-DPPH flow injection hyphenated technique could realize high-flux screening analysis for antioxidant of phytochemicals.江苏省高校自然科学研究计划资助项目(05KJB330083

Effect of geniposide on the lipid metabolism and inflammatory injury of nonalcoholic fatty liver disease in the hamster

目的:观察栀子苷对高脂饮食诱导的金黄地鼠非酒精性脂肪性肝病模型脂质代谢、肝组织病理变化及炎症损伤的影响,并与栀子进行比较,以明确栀子抗脂肪肝作用的效应成分。方法:24只雄性金黄地鼠按随机数字表法分为正常组、模型组、栀子组和栀子苷组。实验后观察肝组织病理学变化,并检测肝组织Tg含量、血清Tg、CHO含量及AlT、AST活性。结果:与模型组比较,栀子组、栀子苷组肝Tg含量、血清Tg、CHO含量及AlT、AST活性均显著降低,且栀子苷对AlT、AST活性的降低作用优于栀子。结论:栀子苷与栀子对高脂饮食诱导的地鼠脂肪肝均有显著干预作用,且栀子苷抗炎症损伤作用优于栀子。Objective: To observe geniposide's effect on lipid metabolism,hepatic tissue pathological change and inflammatory injury of golden hamsters with nonalcoholic fatty liver disease( NAFLD),caused by high fat diet.Compare the geniposide's effect with gardenia to make clear the effective components in Gardenia that can resist fatty liver.Methods: 24 male golden hamsters were averagely divided into control group,model group,gardenia group and geniposide group.The experiment was based on building the model,and then observe hamsters 'general condition and pathological change of hepatic tissue,examine the content of hepatic tissue TG,serum TG,CHO and the activity of ALT,AST.Results: In gardenia group and gardenoside group,The content of hepatic tissue TG,serum TG,CHO and the activity of ALT,AST are significantly lower than the model group.Besides,gardenoside can lower the activity of ALT,AST better than gardenia.Conclusion: Both gardenoside and gardenia have notable intervention effects on hamsters' NAFLD caused by HFD and gardenoside have better effects on resisting inflammatory injury than gardenia,which suggested that gardenoside was the primary effective component in resisting NAFLD.国家自然科学基金面上项目(81274155); 厦门市重大科技计划项目(3502Z20100006

壳聚糖接枝尼龙64及其增容性

通过马来酸酐酰化改性制取水溶性壳聚糖,利用沉淀缩聚方法将尼龙接枝于该水溶性壳聚糖上。通过改变原料的配比得到不同接枝率和溶解性的产物,较合适的原料投料比为n(马来酰化壳聚糖(MACS))∶n(己二胺)∶n(丁二酰氯)=1∶10∶7.5。采用FTIR和1H NMR测试技术表征了壳聚糖接枝尼龙的结构。初步研究表明,壳聚糖接枝尼龙在尼龙和壳聚糖的共混中能起到一定的增容作用

十一种壳聚糖衍生物的紫外吸收特性

通过对O-氰乙基壳聚糖、N-苄基壳聚糖等11种壳聚糖衍生物的紫外吸收特性的研究发现,在稀溶液体系中,这些衍生物的紫外吸收光谱都可以覆盖整个UV-B区(280~320 nm),其中N-羟基苄基壳聚糖、N-苯基乙烯基甲基壳聚糖甚至可以覆盖至UV-A区(>320 nm);大部分衍生物吸收强度可达中等以上,N-苯甲醛西佛碱壳聚糖、N-羟基苄基壳聚糖、N-苯基乙烯基甲基壳聚糖、辛基氨基甲酸酯基壳聚糖、萘基氨基甲酸酯基壳聚糖达到强吸收。而在浓溶液体系中,虽然由于浓度过高不能得到完整的谱图,但是可以通过其出峰位置的移动来说明其聚集态的变化。液晶临界浓度附近,峰的位置移动较大,而将液晶态冻结下来的N-苄基壳聚糖薄膜的紫外光谱已经可以覆盖大部分的UV-A区

Jiangzhi and Hepatoprotective effect of salidroside on nonalcoholic fatty liver disease

目的:探讨中药红景天的主要成分红景天苷对高脂饮食诱导的金黄地鼠非酒精性脂肪性肝炎(nASH)的干预作用。方法:18只雄性金黄地鼠随机分成正常组、模型组和红景天苷组,除正常组外,其余两组均给予高脂饮食喂养6周以复制nASH模型;造模第3周起,红景天苷组给予红景天苷药液灌胃4周。6周后处死地鼠,收集标本,检测肝组织甘油三酯(Tg)含量,血清天门冬氨酸氨基转移酶(AST)活性,对肝组织进行HE染色。结果:红景天苷能明显降低肝组织Tg含量及血清AST活性,改善肝组织脂肪变性的病理状态。结论:红景天苷具有显著的抗nASH病理损伤的药理效应。Objective:To explore the intervening effect of the main components of the rhodiola on the nonalcoholic fatty liver disease(NAFLD) for male golden hamsters induced by high-fat diets.Methods:Total 18 male golden hamsters were divided into control group,model group and salidroside group randomly.Male golden hamsters in the model group and salidroside group were fed with high fat diet for 6 weeks to reproduce NAFLD model.After the second week of feeding,male golden hamsters in the salidroside group were given a gavage of salidroside.All male golden hamsters were put to death at the 6 weeks and samples were collected.Hepatic tissue TG contents were detected.Serum AST activities were determined.Hepatic tissues were detected by HE staining.Results:Salidroside decreased hepatic tissue TG contents,serum AST activities and reduced the fatty degeneration in hepatocytes significantly.Conclusion:Salidroside has conspicuous pharmacological effect on the nonalcoholic fatty liver disease in male golden hamsters.国家自然科学基金(No.81274155); 厦门市重大科技计划项目(No.3502Z20100006); 横向课题(No.XDHT2011366A)~

N-烷基壳聚糖玻璃化转变温度的研究

采用差示扫描量热(DSC)法和热释电流(TSC)法研究了N-烷基壳聚糖的玻璃化转变行为.DSC法中采用二次扫描以消除溶剂和热历史的影响,并利用物理老化方法来增强N-烷基壳聚糖在DSC曲线上的玻璃化转变区域的热焓吸热峰,以克服DSC法的不灵敏性.两种研究方法的结果一致表明,三种N-烷基壳聚糖的玻璃化转变均发生在110～150℃温区内;取代的柔性烷基越大,玻璃化转变温度(Tg)越低;但N-甲基壳聚糖例外,其Tg略高于壳聚糖,空间阻碍在这里起决定的作用

甲壳素类液晶高分子的研究——用CD谱研究N-邻苯二甲酰化壳聚糖溶致胆甾相的形成临界浓度

N邻苯二甲酰化壳聚糖在多种常见有机溶剂中能形成胆甾液晶相.用圆偏光二向色性谱(CD)研究了N邻苯二甲酰化壳聚糖的DMF、DMSO、DMAC和吡啶4种溶剂体系,在形成溶致胆甾液晶相前后的手性变化信息.CD谱图上观测到两类吸收,即在400nm附近较宽的吸收和330nm附近较尖锐的吸收.前者归属于胆甾相层片的超分子螺旋构象,而后者可以归属于分子链的螺旋构象.圆偏光二向色性可以作为测量胆甾液晶临界浓度的一种手段,它能捕捉到胆甾螺旋层片出现那一瞬间的浓度,以CD谱上在波长400nm左右刚出现肩峰的浓度为临界浓度,其值均比偏光显微镜法低1%,说明其灵敏度比偏光显微镜法高,且避免了偏光显微镜法的某种主观性.分别用两种方法旋转玻片进行CD测试,结果证明线性二向色性分量和双折射分量对胆甾层片螺旋的CD信号强度没有大的影响

1978～2008年中国湿地类型变化

分别基于美国陆地卫星(Landsat MSS/TM/ETM+)和中巴资源卫星(CBERS-02B)影像数据,以人工目视解译为主,完成了中国1978～2008年4期(基准年分别为1978,1990,2000和2008年)湿地遥感制图,并进行了大量的室内外验证.在此基础上,对我国湿地现状及近30年来湿地变化进行了初步分析,得到以下主要结论:(ⅰ)截止2008年,中国湿地面积约为324097km2,其中以内陆沼泽(35%)和湖泊湿地(26%)为主.(ⅱ)1978～2008年,中国湿地面积减少了约33%,而人工湿地增加了约122%.过去30年里湿地减少的速度大幅降低,由最初5523km2/a(1978～1990年)降为831km2/a(2000～2008年).(ⅲ)减少的自然湿地(包括滨海湿地和内陆湿地),其类型变化由湿地向非湿地转化的比例逐渐降低.初期(1978～1990年)几乎全部(98%)转换为非湿地;在1990～2000年间减少的自然湿地约有86%转化为非湿地,而在2000～2008年,这一比例下降为77%.(ⅳ)气候变化和农业活动是中国湿地变化的主要驱动因素,湿地变化在中国分为三大不同特征区域,即西部三省/自治区(西藏、新疆和青海)、北部两省/自治区(黑龙江和内蒙古)和其他省市区.其中西部区域尤其是青藏高原,湿地变化的驱动因子以气候增温为主;新疆湿地由于气候增温和农业活动共同作用造成变化不大.北部省/自治区的湿地变化则主要由农业活动引起;而其他省市区的湿地变化几乎完全受控于人类的农业经济活动