不同剂量氯吡格雷对急性脑梗死患者神经功能及预后不良事件的影响

目的探讨不同剂量氯吡格雷治疗急性脑梗死(CI)患者的效果及安全性。方法选取86例急性CI住院患者,采用简单随机分组法分为大剂量组(n=43)与小剂量组(n=43)。在常规对症治疗基础上,大剂量组给予氯吡格雷150 mg,小剂量组给予氯吡格雷常规剂量75 mg,均持续治疗3个月。比较2组治疗前后血小板计数、血小板聚集率、美国国立卫生研究院卒中量表(NIHSS)评分、预后不良事件发生情况。结果大剂量组治疗后血小板计数、血小板聚集率、NIHSS评分均较治疗前显著下降(P 0.05)。大剂量组神经功能恶化率4.65%,低于小剂量组18.60%,差异有统计学意义(P <0.05)。结论与标准剂量75 mg氯吡格雷比较,大剂量150 mg氯吡格雷的抗血小板聚集效果更加显著,能有效促进CI患者神经功能恢复

医院感染多重耐药菌分布及耐药性分析

目的了解医院感染多重耐药菌分布及耐药性分析,为临床诊疗提供依据。方法 25 618例临床感染标本分离株培养鉴定后,监测常见分离菌的多重耐药菌株(MdrO)。结果 1 087株分离菌以革兰阴性菌925株为主,革兰阳性菌162株。革兰阴性菌中分离率前5位分别是肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌、鲍曼不动杆菌、阴沟肠杆菌。革兰阳性菌中分离率前5位分别是金黄色葡萄球菌、凝固酶阴性葡萄球菌、肺炎链球菌、屎肠球菌、粪肠球菌。大肠埃希菌、肺炎克雷伯菌产超广谱β-内酰胺酶(ESblS)株的检出率分别为75.53%、37.14%;金黄色葡萄球菌中耐甲氧西林的金黄色葡萄球菌(MrSA)的检出率为78.20%,凝固酶阴性葡萄球菌中耐甲氧西林的凝固酶阴性葡萄球菌(MrCnS)的检出率为84.60%。13株屎肠球菌中发现3株万古霉素耐药株(VrE)。结论医院感染多重耐药菌分布主要以革兰氏阴性杆菌为主,其次是革兰氏阳性球菌。MdrO的增多是医院面临的重要问题,在临床上应改进治疗手段,合理使用抗菌药物,减少MdrO的产生和播散

The progress in the study of Arctic pack ice ecology

The sea ice community plays an important role in the Arctic marine ecosystem. Because of the predicted environmental changes in the Arctic environment and specifically related to sea ice, the Arctic pack ice biota has received more attention in recent years using modern ice-breaking research vessels. Studies show that the Arctic pack ice contains a diverse biota and besides ice algae, the bacterial and protozoan biomasses can be high. Surprisingly high primary production values were observed in the pack ice..

南极海冰区冰藻类群及兴衰过程

本文总结了国际上对南极冰藻类群及其生理生态特性的多年研究成果 ,结合我国科学家在南极长城站以及在戴维斯和中山站的越冬研究 ,阐述了南极海冰区的冰藻类群及其形成机理 ,对冰藻的形成、存活、旺发和消亡过程进行讨论 ,并对大洋浮冰区和近岸固定冰区冰藻类群的生态特性进行对比 ,提出了今后有待进一步深入研究的领域 【英文摘要】 Combining with the research results obtained from the Great Wall and Zhongshan Stations of China, the thesis reviews the different ice algal assemblages occurring in the Antarctic sea ice and their formation, survival, growth and disappearance, compares the difference between the pack and fast sea ice zones and brings forward some scientific questions which are needed for further research. There are surface, interior, bottom and sub ice assemblages within ice, and each composes of some types. Because of ...国家自然科学基金项目 ( 30 2 70 112 ;4 0 0 0 6 0 10 )资

Water quality assessment on Tongan Bay, Xiamen

根据 1 995～ 1 999年同安湾海域的水质监测资料 ,对海域的水质状况进行了评价和营养分级。结果表明 ,海域水质处于高N低P状态。pH、DO、CODMn、和BOD5 符合GB 30 97 1 997第二类海水水质标准 ,但DIN、石油类和DRP超第二类海水水质标准。DIN和石油类的超标率和超标倍数有逐年增强之势。该海域目前处于P中等限制潜在性富营养水平阶段。Based on the survey data in Tongan Bay of Xiamen from 1995 to 1999, the assessments and classification for water quality and the nutrient levels were respectively done. The results shown: (1) The survey area has the typical characteristics of rich nitrogen and low phosphorus. (2) The contents of pH, DO, COD Mn and BOD 5 are coincide with the sea water quality standard of GB 3097 1997, and the contents of DIN, DRP and Oil are beyond the standard. (3) Tongan Bay was at the stage of middle phosphorus limited potential eutrophication

The abundance and diversity of nanoplankton in Arcitic Ocean

近年来随着全球气候变化对北冰洋生态环境的影响日益显现,北极微型浮游生物生态学研究得到了广泛的重视和实质性的进展。对北冰洋微型浮游生物的主要类群:异养细菌、古菌、光合异养原核生物和微型真核生物的分布及其多样性研究进展做了概述,并在此基础上展望了未来北冰洋微型浮游生物学研究。Asthe most abundant and the most taxonomically and genetically diverse organisms in the marine ceosystem,nanoplankton predominate in the marine system concerning their bioactivity,biomass,and production.They play an important role in the carbon fixation process in the Arctic Ocean,and are an important component to regulate the biosphere.Furtherly,nanoplankton can be an important indicator of the changing environment,since the changes in the community,structure and biomass of nanoplankton reflect the changes in the pathways of nutrient and energy transferring in the food web and the changes in the biogeochemical cycle.Recently,ecology study of the Arctic nanoplankton has been paid more attention due to the increasing impacts of climate change on the Arctic marine ecosystems.Substantial progress has been achieved.The Arctic heterotrophic bacteria were reported to resemble those in the seas of lower altitudes in their high abundance and biomass with seasonal successions.Particle-associated bacteria often show a higher specific metabolic activity than the free-living communities.So far,there are few reports on the proteorhodopsin(PR)-containing bacteria.High diversity has been reported for this group in the Chukchi Sea,which can be attribute to yariable bacteria communities.A large number of aerobic anoxygenic phototrophic(AAP) bacteria have been found in the Chukchi Sea with a distinctly seasonal succession.The photosynthetic group in the Arctic Ocean was found to be mostly composed with the nanoplankton(≤20μm),described as a polar ecotype of the small prasinophyte Micromonas.The high correlation between the abundance of coccoid cynaobacteria and temperature results their low abundance at the high latitudes There are only a few studies of Synechococcus in the coastal Arctic Ocean.The Micromonas is proved to be ubiquitous throughout the Arctic Ocean,especially at the chlorophyll-maximum layer,and may be a major contributor to the primary production in the Arctic Ocean.Until now little is known about the distribution of heterotrophic nanoflagellates in the Arctic Ocean,compared with phytoplankton and prokaryotes.Many scientific questions,which deserve special attention,remain unsolved due to lack of continuous sampling and the complexity of the nanoplankton characteristics.Some of them have been highlighted here in the Arctic nanoplankton ecology.(1) More attention should be paid to the effect of the climate change on the nanoplankton community in the Arctic Ocean,considering its major and often dominant contribution to the total ecosystem.(2)Most of the investigations of nanoplankton community are focused on the Atlantic Arctic Ocean of the Arctic Ocean.It is necessary to investigate the community structure of the nanoplankton in the entire Arctic Ocean.(3) As a photoheterotrophic microbe,AAP bacteria may play a special role in the ecology in the Arctic Ocean.However,little is known about the distribution,abundance,and diversity of the AAP bacteria in Arctic Ocean.(4)Archaea seems to be of special significance in the Arctic waters with large population existing in the surface water.More work need to be done on their diversity and their functions in the energy flow.国家自然科学基金(40576002;41076130);国家海洋局青年基金项目(2010116

天葵秋海棠根部的化学成分

天葵秋海棠（ＢｅｇｏｎｉａｆｉｍｂｒｉｓｔｉｐｕｌａｔａＨａｎｃｅ）是秋海棠科秋海棠属植物，别名紫背天葵，分布于江浙、福建、两广、四川和云南等地，以块茎和全草入药，称为散血子，具清热凉血、止咳化痰、散瘀消肿功效，可治中暑发烧、咳嗽咯血、淋巴结核、血瘀..

基于联合分离原子模型的电离理论

采用微扰静态(PSS)模型近似处理极化和结合能效应,并引入了相对论效应、能量损失效应和库仑偏转效应修正的ECPSSR理论是描述直接库仑电离过程最成功的理论,但对于低能离子入射时,其结果明显低于实验值.采用联合分离原子(USA)模型替代ECPSSR中的PSS模型,考虑分子轨道效应得到了基于USA模型的电离理论——MECUSAR理论.对部分碰撞系统进行了计算,得到的碰撞截面与实验结果基本符合.结合OBKN(Oppenheimer-Brinkman-Kramers formulas of Nikolaev)电子俘获模型,对MECUSAR理论进行了进一步修正,使其能对不同电荷态的入射离子进行计算

三峡地区河岸带植物群落的特征及其分类与排序研究(英文)

本文以长江三峡干流河岸植物群落为研究对象,对群落的物种组成、物种多样性进行了分析,并利用TWINSPAN和DCA对植物群落进行等级式划分。结果表明:河岸植物区系组成较为复杂,以温带成分为主,有着较高比率的世界分布成分。灌、草丛群落之间的物种多样性差异不显著,但部分草丛的不同层次间存在较大差异。TWINSPAN 和DCA分析显示,河岸植物群落呈现沿湿度梯度方向的分布格局。图2表3参8

神农架地区珍稀植物沿河岸带的分布格局及其保护意义

在神农架香溪河流域从源头到河口的不同海拔高度沿河岸带共设置 4 0个与河流方向平行的10 0m&times; 10m的样带 ,进行了植物群落学调查研究 .结果表明 ,沿河岸带分布有珍稀植物 14种 ,占神农架地区珍稀植物总数的 4 2 .4 % .这些珍稀物种主要分布在海拔 12 0 0～ 180 0m山地常绿阔叶落叶阔叶混交林带 ,珍稀植物种类的物种丰富度在中等海拔高度上最大 .珍稀植物的种类可划分为低海拔、中等海拔和高海拔 3组 .针对珍稀植物的分布特点 ,明确指出应重视河岸带在生物多样性、尤其是珍稀物种保护方