Design and Implementation of Pharmaceutical Inventory Management System for Community Hospital

药品管理关系患者及时治疗、医院的正常运转，是医院的重要管理工作之一。实际中，社区医院由于规模较小，缺乏相应的管理系统，传统的手工药品管理模式已经跟不上医院的发展与患者的需求。以幸福社区医院为例，通过与医院的工作人员交流得知，幸福社区医院每到月底均开展例行药品库存审查和绩效查询工作，需要绘制处理大量的相关信息表格。由于缺乏相应的存管理系统，实际情况中库存数据常常难以精确统计且容易出现很多错误，返工率极高，亟需要通过信息化手段实现药品库存管理，满足患者的各种需求，提高社区医院药品管理的工作效率及水平。 基于幸福社区医院的实际情况，本文设计并实现社区医院中医药库存管理系统，实现基本库存管理功能信息...The normal operation of drug inventory, related to patients’ treatment, is one of the most significant management work of the hospital. In practical situations, community hospital, small scale, without appropriateinformation system, have behind the patient's needs in traditional manual drug management mode. Taking X community hospital as example, it carried out routine drug inventory review and pe...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201223079

The basic research progress of catalytic chemistry in China in 2008 based on the published papers

依据我国催化领域的学者在一些重要国际学术刊物上发表的论文,从能源和化工催化、环境催化、绿色催化、手性催化、有机合成中的多相催化、光催化、催化新材料和催化剂新合成方法、催化活性中心和催化反应机理表征等方面,简要介绍2008年我国催化学科在基础研究方面所取得的一些进展.This review highlights fundamental research progress in catalysis discipline in China in 2008 based on the scientific papers published in some prestigious international journals related to catalysis.The present review mainly includes the following aspects:catalysis for energy and chemical processes,environmental catalysis,green catalysis,chiral catalysis,heterogeneous catalysis for organic synthesis,photocatalysis,novel catalytic materials and catalyst synthetic methods,characterizations of active sites and reaction mechanisms

Antitumor effects of a novel chloroquinoline derivative as EGFR inhibitor on human esophageal carcinoma

目的:评价Egfr抑制剂4-取代-7氯喹啉衍生物(TW9183)的体内外抗肿瘤生物活性。方法:采用分子对接技术探讨其与Egfr之间的相互作用模式,蛋白免疫印迹法评价在蛋白水平的直接作用,体外细胞生物学及体内裸鼠移植瘤模型探讨TW9183的活性。结果:Egfr受体的氨基酸残基MET769,PrO770,lyS721可与TW9183间形成氢键,蛋白印免疫迹法表明化合物抑制Egfr的磷酸化;体外细胞实验显示TW9183有明显抑制食管癌细胞增殖、周期阻滞于g2/M期及促进凋亡的效果;裸鼠食管癌移植瘤模型验证其在体内同样具有抑制肿瘤生长促进凋亡的作用。结论:TW9183在体内外实验中显示具有潜在的抗食管癌作用。Objective: To explore the underlying mechanism of 4-substituent-7-chloroquinoline derivative(TW9183),which has a selective anti-tumor effect in vitro and in vivo.Methods: Docking simulation was performed to position compounds into the EGFR structure active site to determine a possible binding model.We also used Western blot assay to directly evaluate the interaction.Cell cultures and tumor xenografts were utilized to test the effect of TW9183.Results: TW9183 was nice bound to the EGFR with the amino hydrogens of MET769, PRO770 and LYS721,forming optimal H-bonds interaction.Western blot assay showed that the compound inhibited EGFR phosphorylation.TW9183 treatment increased typical apoptosis and the number of cells in the G2/ M phase in ECA-109 cells.In ECA-109 xenograft model in nude mice,TW9183 inhibited tumor growth and promoted apoptosis.Conclusion: TW9183 has potential antitumor activity in vitro and in vivo.泉州市科技计划重点项目(2013Z35

Design of Teaching Activities in Universities based on Network Platform and Information Technology

随着计算机、手机和平板电脑的迅速发展,网络平台的运用和涉及的范围越来越广泛,信息技术应用于现代教学中是-种必然的趋势.文章讨论网络平台和信息技术在现代教学中的运用,以“慕课”和课堂教学混合模式为例,展开讨论网络平台和信息技术在国内高校课堂教育中发挥的作用,对比慕课在线课程和传统课堂优劣,探究如何有效运用慕课在线学习平台和信息技术进行教学活动设计,开展混合教学,提高课堂教学质量.With the rapid development of computer, mobile phone and tablet PCs, the use and the cov-erage scope of network platform are becoming more and more widely. It becomes an inevitable trend to apply the computer information technology into the modem teaching. This paper discusses the application of network platform and information technology in teaching and takes the blended mode of MOOC （Massive Open Online Course） and traditional teaching as an example to discuss the role of the network platform and information technology played in the classroom education of domestic universities. Comparing the advantages and disadvan-tages of MOOC online courses and traditional classroom teaching, we explore how to use the MOOC online learning platform and information technology effectively to design teaching activities and carry out blended teaching to improve the quality of classroom teaching.厦门大学示范性网络课程建设项目“生物化工、微生物学实验、食品安全与健康饮食、出国留学指导”

生物工程专业英语教学改革的实践与思考

生物工程专业英语作为专业课程与大学英语教学的一个重要组成部分,为培养既具生物工程学科专业知识,又具备听、说、读、写等全面发展的复合型人才起着重要的作用。文章结合笔者在教学改革实践过程中得到的一些体会,针对当前高校生物工程专业英语的教学现状,阐述了生物工程专业英语教学难点与重点,指出当今专业英语教学所存在的问题,并对其解决方案——\"翻转课堂\"\"任务式\"与\"参与式\"教学等进行了深入思考。厦门大学示范性网络课程建设项目“生物化工、微生物学实验、食品安全与健康饮食、出国留学指导

高超声速飞行器多约束再入轨迹快速优化

针对高超声速飞行器再入过程中面临测控区和绕飞区的再入轨迹设计问题,提出了一种基于Gauss伪谱法(GPM)的分段轨迹优化策略。将轨迹优化的一般最优控制问题转换为多段最优控制问题,进而将各段轨迹按Gauss伪谱方法进行离散化,将连续多段最优控制问题转换为非线性规划问题(NLP)进行求解。所得再入轨迹能够使得飞行器在满足各种约束条件的情况下成功进入测控区并且有效规避绕飞区,最终到达指定点。此外,本文综合考虑飞行器再入飞行的快速性和工程实用性,并提出了再入时间、弹道倾角以及航向角相关指标的加权性能指标,同时保证了轨迹规划快速、再入轨迹平滑以及控制量变化平缓等实际需求,提高了计算效率。仿真结果表明,本文所提出的分段优化方案能够快速规划出适应不同飞行任务的再入轨迹

Study on species diversity of macrobenthos in Daya Bay,South China Sea

利用2004年3月、5月、9月和12月的大型底栖动物定量采样数据,对大亚湾大型底栖动物的物种多样性进行研究。结果表明,因人类活动影响的加剧,目前大型底栖动物多样性明显低于历史水平。2004年大亚湾海域内共出现79种(类)大型底栖动物,全海域均匀度(J)、丰富度(D)和Shannon-Wiener指数(H′)均值分别为1.17、0.74和2.06。各多样性指数的季节变化较小,不存在显著差异(P>0.05)。多样性水平以冬季0.05).The level of species diversity showed the trend of winter < spring < summer < autumn.It has been found that the distinct change of dry and wet season,the species diversity in wet season was higher than those in dry season.The species diversity of macrobenthos in outer Bay was the highest among other areas.The dominant species of Veremolpa micra and Timoclea scabra were so abundant that the species diversity of macrobenthos in center Bay and inner Bay were low.The seasonal change of the species diversity of macrobenthos in center Bay and inner Bay was caused by the change of the abundance of V.micra and T.scabra.Then the abundance of V.micra and T.scabra fluctuated with the water temperature directly.科技部社会公益研究专项资金项目(2005DIB3J020);; 广东省重大科技兴海项目(A200099E01);; 中央级公益性科研院所基本科研业务费专项资金(中国水产科学研究院南海水产研究所)资助项目(2007ZD08);; 农业部海洋与河口渔业重点开放实验室基金项目(开-2-04-15);; 农业部渔业生态环境重点开放实验室开放基金项目(2004-22005-2

Macrobenthic community structure in Daya Bay,South China Sea

利用2004年3月、5月、9月和12月的大型底栖动物定量采样数据,对大亚湾大型底栖动物的群落结构进行研究。结果表明,大亚湾大型底栖动物大致可分为3个群落,分别分布于湾顶及湾中大部分海域、湾中部和湾口海域,湾中部海域群落的变化较为显著。大型底栖动物整体群落结构的季节变化总体较小,但雨季对大型底栖动物群落的影响较大,存在较明显的干湿季差异。大亚湾海域生态环境受到明显的扰动,处于扰动状态中的大型底栖动物群落稳定性较差;湾顶和湾中大部分海域内的群落Ⅰ,为大亚湾的主体群落,以软体动物为主,种类组成单一、季节变化小,以小鳞帘蛤VErEMOlPA MICrA和粗帝汶蛤TIMOClEASCAbrA为特征种。该群落的稳定性最差,处于较强烈的扰动之中;稳定分布于湾口的群落Ⅲ稳定性最好,未受到扰动,以多毛类为主,种类组成较为复杂、变化较大;湾中部海域大型底栖动物群落结构变化较为复杂,主要变化区域为马鞭州附近海域。该群落系经强烈的人为扰动后,经次生演替而形成的新群落,其种类组成的季节变化非常显著,各季的种类几乎完全不同,群落的独立性和抗干扰能力均较弱;与1980'S相比,大亚湾大部分区域内大型底栖动物基本保持了原有的群落,但群落稳定性大幅下降,群落的分布范围和种类组成发生较大程度的改变,主体群落组成呈明显的简单化趋势。在人类活动影响下,湾内同一区域内群落完全演替、湾中部海域出现新的群落。Based on macrobenthos samples collected from 4 survey cruises at 40 research stations in March,May,Sept.and Dec.2004 in Daya Bay,South China Sea,the community structure of macrobenthos was studied.The result showed that macrobenthos community in Daya Bay can be divided into three groups from the inner bay to the main area of the central bay,the central bay and outer bay.The effect of changes between wet and dry seasons on the macrobenthos community structure in Daya Bay was relatively stronger,although seasonal effect on the overall community structure was small.Daya Bay was shown to be ecologically disturbed and the stability of macrobenthic community was weak.Specifically,the inner bay and main area of the central bay was strongly disturbed and was dominated by Group I community that was characterized as simple low stability and dominated by molluscs.Dominant species were Veremolpa micra and Timoclea scabra.The outer bay received little disturbance and the community was most stable.The community belongs to Group Ⅲ that was dominated by polychaete and characterized as complicated and variable.The community change in the central bay was more complicated,concentrated mainly around Maiban Zhou.Its community structure was strongly affected by human disturbance and largely different from other community groups.Species composition of the group was variable which differed largely between seasons.The stability and resilience of the community is low.The current macrobenthic community in Daya Bay is different from the 1980s' state with largely different species composition,reduced community stability and complexity.Overall,under human disturbance,the macrobenthos community in Daya Bay,and particularly in the central bay,changed to a totally different structure.中央级公益性科研院所专项基金资助项目(2007ZD08;2007ST08);国家科技部公益资助项目(2005DIB3J020);广东省重大科技兴海资助项目(A200099E01);国家农业部海洋与河口渔业重点开放实验室基金资助项目(开-2-04-15);国家农业部渔业生态环境重点开放实验室开放基金资助项目(2004-2、2005-2