Design and Implementation of Personnel Management System for an Enterprise

随着互联网时代的到来，互联网技术逐渐成熟，网络办公自动化的兴起，为企业及个体的管理带来极大的方便，网络化办公作为新时代工作模式的一个发展方向的代表，其成为了现代管理模式不可或缺的一部分。在人事管理方面，传统采用手工方式存在诸多问题，特别是数据的缺漏和误报等问题，给企业带来了巨大损失。如何有效地结合企业人事管理具体现状，研发一套人事管理信息化系统就显得尤为重要。 本文论述某企业人力资源管理系统的设计与实现，该系统采用java语言，基于B/S三层结构模式，以MySQL.作为数据库开发。该系统从三个不同的权限角色出发，具体包括人事管理员功能子系统、员工功能子系统、系统管理员功能子系统。论文主要内容...With the advent of the era of Internet, the Internet technology mature gradually, the rise of the network office automation, management bring great convenience for enterprise and individual, network office work mode as a new era of representatives of a development direction for an integral part of modern management mode. The shortcoming of traditional personnel manual management has become increas...学位：工学硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323115

Ritual Performing and Memory Practicing——a Case Study of the Ritual of Song-ning in a Bouyei Village

铜鼓是布依族的神器礼器。布依族送、迎铜鼓的"送宁"仪式,在具体实践展演过程中,产生重大的社会—文化作用:一方面使民族文化在实践记忆中得以唤醒重现和传播继承,另一方面增强了族群的社会记忆和自我认同。实践记忆的情境性和在场性特点,在民族文化的保存再现和传承播布等方面都具有重要的文化意义。Brass drums are the Bouyei people's instruments of deity worshipping.The ritual of song-ning, or the presenting and receiving of brass drums,has cultural significance in performance.On the one hand,it reminds the Bouyei people of their own culture and contributes to its inheritance.On the other hand,ethnic memory and identification is strengthened.The situational and on-the-site practice of invoking memory is conducive to the retention and dissemination of ethnic cultures

Kinetics of propylene polymerization catalyzed with CS-1 catalyst

采用聚合实验并结合理论模拟技术对CS-1型高效聚丙烯催化剂的聚合动力学进行了研究。对通过聚合实验所获取的聚丙烯凝胶渗透色谱(gPC)进行解析,得到CS-1型聚丙烯催化剂的最可几活性中心数目。以此为基础,通过理论模型耦合实验结果确定了各活性中心的聚合动力学方程及各自动力学参数取值。此外,采用扩充的实验结果对模型进行了考核。结果表明,文中所建立的多活性中心动力学方程可以用来表征CS-1型聚丙烯催化剂的聚合动力学行为。Based on the experiment and simulation technology,the kinetics of propylene polymerization catalyzed with CS-1 catalyst was studied.The gel permeation chromatography(GPC) data of polypropylene obtained by polymerization experiment were analyzed and the number of the most probable active sites was obtained.In addition,the corresponding propylene polymerization kinetic model was established and its parameters were also obtained.Furthermore,the kinetic model was testified by the polymerization experiment.The results show that the model established can be used to characterize the kinetics of propylene polymerization catalyzed with CS-1 catalyst.2008年度甘肃省教育厅科研项目(0814B-01

Study advances in modeling for polyolefin particle growth

在聚烯烃生产过程中,聚烯烃颗粒粒径(大小及其分布)影响聚合速率、气力输送、后处理工序生产成本和最终的聚烯烃物性。为预测甚至调控生产过程中聚烯烃颗粒粒径,近期出现了许多烯烃聚合颗粒增长的模型化研究报道。本文简要介绍并比较了迄今所出现的主要聚合物颗粒增长模型,并指出如何用模型来描述聚合物颗粒增长情况。In the polyolefin preparation process,polymerization rate,fluid transport,and the cost of post-treatment after polymeric process and polymer properties may be affected by the polymer particle size and its distribution.In order to predict and control the polyolefin particle,many literatures report the models for polyolefin particle growth.In this paper,the main models on the particle growth are introduced and compared each other,while describing the mechanism of the polymer particle growth via model.中国石油化工股份有限公司福建炼油化工有限公司资助项目(G7808-06-ZS-1006

MONTE CARLO SIMULATION of SINGLE-/MULTI-ACTIVE SITE CATALYSTS FOR PROPYLENE POLYMERIZATION

采用MOnTE CArlO模拟技术研究了在不考虑聚合物颗粒内物料与热量传递效应及不存在氢气作用下的单、多活性种类催化剂催化的丙烯聚合动力学。探讨了聚合产率、催化剂活性中心分率以及多分散指数随时间的变化规律,并对单、多活性中心种类催化的反应体系分别作了比较。基于MOnTE CArlO方法的模型得出的聚合动力学结果与文献相一致。此外,由MOnTE CArlO模拟也得到,催化剂多活性中心种类的性质对聚合产物的分布性质有很大影响;以多分散指数而言,多活性中心种类催化剂催化得到的聚丙烯多分散指数要比单活性中心种类催化剂催化得到的产物多分散指数宽。A Monte Carlo model was established to describe the propylene polymerization kinetics catalyzed by single-or multi-active site catalyst,ignoring the effects of intraparticle mass and heat transfer and the effect of hydrogen.Corresponding propylene polymerization kinetic data,including polymerization yield,concentration transformation of catalyst active sites,polydispersity etc.,were obtained via the model.Comparisons of the kinetic results between the polymerization catalyzed by the single-active site catalyst and the multi-active site type catalyst were conducted via the model.The simulated kinetic results are found to be in agreement with the reference ones obtained experimentally.The studied results showed that nature of multi-active site type could have a significant influence on polymer distribution properties.As of the polydispersity(PDI),polypropylene catalyzed by multi-active site type catalyst has a broader PDI than the one catalyzed by the single-site catalyst,under the same reaction circumstance.中国石油兰州石油化工研究中心课题(2007019);固体表面物理化学国家重点实验室(厦门大学)课题(200505)项目资

STEADY-STATE MODELING of COMMERCIAL LIQUID PHASE BULK PROPYLENE POLYMERIZATION

采用POlyMErS PluS软件对HyPOl聚丙烯工艺进行了模拟。建立了与现场流程及POlyMErS PluS软件均相匹配的模拟流程;采用PC-SAfT状态方程,并根据zIEglEr-nATTA催化体系的丙烯聚合机理,确定了丙烯聚合动力学。此外,通过文献提供的现场数据分析并确定了丙烯聚合动力学参数。最终建立了完整的HyPOl工艺流程模型。以采集的工业数据对模型进行验证,并采用模型考察了工业稳态操作下的主要工艺条件对丙烯聚合过程的影响。结果表明,模拟结果与工业现场采集数据比较吻合。随着H2进料量增加,聚合产品的熔融指数(MI)增大,数均相对分子质量(Mn)及其多分散分布指数(PdI)下降;催化剂及丙烯进料量的增加都将使各反应釜的聚合物产量增加。The HYPOL technology of polypropylene was simulated by Polymers Plus.First,a flowsheet which incorporates the actual technology into Polymers Plus was obtained.In addition,based on the perturbed-chain statistical associating fluid theory(PC-SAFT) and the propylene polymerization mechanism catalyzed by Ziegler-Natta catalyst,the propylene polymerization kinetics was obtained.Simultaneously,the polymerization kinetic parameters were obtained through the industrial dada provided via literature.Accordingly,the whole process model of the HYPOL technology was developed.The comparison between the simulated and plant data showed that they were in good agreement with each other.The model was also used to investigate the effects of the main operation parameters on the propylene polymerization under steady-state condition.The results indicated that the polymer melt index(MI) increased and the number average relative molecular mass(Mn) of the polymer and its polydispersity index(PDI) both decreased with the increase of the H2 flow rate.The polymer yield increased with the increase of the feed flow rate of catalyst and propylene.中国石油天然气股份有限公司兰州石油化工研究中心资助项

Intraparticle Mass and Heat Transport Model of Polypropylene in a Loop Reactor

针对环管反应器中zIEglEr-nATTA催化剂催化的聚丙烯颗粒增长过程,采用多层模型建立了聚丙烯颗粒内部的质量与热量传递预测模型。通过模型模拟得到聚丙烯颗粒内部的丙烯单体浓度梯度和温度梯度。此外,通过模型分析了聚丙烯颗粒的增长规律。结果表明,环管反应器中的聚丙烯颗粒内部的单体浓度梯度明显,该浓度梯度值随扩散系数的增大而减小,随催化剂初始粒径减小而减小;相比于浓度梯度而言,聚丙烯颗粒内部的温度梯度并不明显,温度值随聚合进行而增加,温度梯度则随催化剂初始粒径的增加而增加;不同大小的催化剂颗粒增长得到的聚丙烯颗粒的增长倍数不同。In the present study,the multilayer model(MLM)was used to describe the intraparticle mass and heat transport phenomena of polypropylene produced by propylene polymerization with the Ziegler-Natta catalyst in a loop reactor.Accordingly,the monomer concentration gradient and temperature gradient in the polymer particles and the rule of polymer particle growth were obtained based on the MLM.The results show that the intraparticle monomer concentration gradient is obvious,while the intraparticle temperature gradient is not so evident.Moreover,the simulated intraparticle monomer concentration gradient decreases with the increase of the value of the diffusion coefficient and decreases with the decrease of the original catalyst particle size.In addition,the intraparticle temperature increases with the increase of the polymerization time and the intraparticle temperature gradient increases with the increase of the catalyst original particle size.The results also show that the growth multiple of the polypropylene particle changes with the change of the original particle diameter of the catalyst.中国石油化工股份有限公司资助项目(x505029

ANALYSIS ON INFLUENCING FACTORS OF PARTICLE SIZE DISTRIBUTION IN PROPYLENE POLYMERIZATION LOOP REACTOR BASED ON PARTICLE POPULATION

在液相本体法环管反应器聚丙烯生产过程中,聚丙烯颗粒粒径分布影响聚合速率、气力输送、后处理工序生产成本和最终的聚丙烯物性,特别是对后续工序有流化床烯烃共聚的工艺有重要影响。为预测环管反应器中聚丙烯的粒径分布,考察各操作变量和动力学参数对聚丙烯粒径分布的影响,运用了粒群衡算方法。在综合分析环管反应器中物料流型、聚丙烯颗粒动力学和聚丙烯颗粒生长的基础上,建立了稳态操作时聚丙烯颗粒粒径分布预测模型。模型计算结果表明,当单一粒径催化剂进料时,随着催化剂粒径或是预聚合与主聚合反应温度的增加,聚丙烯粒径分布向大粒径方向偏移,且分布变宽;相比于反应温度,催化剂粒径作用更为显著。同时发现,丙烯进料流速对聚丙烯粒径分布的影响很小。在催化剂粒径有分布的情况下,不同粒径催化剂的质量比不但影响聚丙烯的平均粒径,而且也影响其粒径分布曲线,并在一定的质量比下会出现双峰颗粒粒径分布曲线。In a propylene polymerization loop reactor,polymerization rate,fluid transport,and cost of post-treatment after polymeric process and polymer properties may be affected by polymer particle size distribution,especially when a co-polymerization technology including olefin polymerization fluidized-bed reactor is followed.In order to investigate the effects of operation parameters and kinetics parameters on the polypropylene particle size distribution in the loop reactor,a steady-state particle size distribution model was developed,in which the flow type in the loop reactor,polypropylene particle dynamics and the particle growth were taken synthetically into account based on the mass balance and solid population balance.The result showed that for uniform size catalyst feed,by increasing either initial catalyst size or the reaction temperature of the main polymeric reactor,the polypropylene particle size distribution in loop reactors became boarder and shifted to larger size,in comparison with the reaction temperature,the effect of catalyst particle size was obvious.The effect of propylene feed rate on polypropylene particle size distribution was much smaller.It's also shown that the ratio of catalyst masses with different sizes in the case of multi-size catalyst feed strongly affected not only the average polypropylene particle size,but also the particle size distribution in the loop reactor.Bimodal polypropylene particle size distribution can be obtained by using a catalyst feed with a distinct particle size distribution.国家自然科学基金(20406016);; 中国石油化工股份有限公司福建炼油化工有限公司项目(G7808-06-ZS-1006)资

(RGD)_3-tTF融合蛋白选择性结合结肠癌裸鼠模型肿瘤血管的实验研究

背景与目的:肿瘤血管作为肿瘤分子靶向治疗的靶点受到广泛的关注,近年来有报道称利用抗体(Ab@作为组织因子(TF@胞外区截短组织因子(truncated tissue factor,tTF@的载体,表达的抗体--截短组织因子(Ab-tTF@融合蛋白能够选择性结合肿瘤血管,诱发实体肿瘤组织血管栓塞,导致肿瘤衰退,但是该方法存在一些弊端。本实验旨在研究以精氨酸-甘氨酸-天冬氨酸(GRGDSP,RGD@多肽作为tTF载体所表达的(RGD@3-tTF融合蛋白选择性结合结肠癌裸鼠模型肿瘤血管的能力。方法:用3个串联的RGD多肽与tTF合成融合基因(RGD@3-tTF,表达于大肠埃希菌(Escherichia coli,E.coli@BL21(DE3@,用镍柱纯化融合蛋白。用RGD-tTF融合蛋白作对照,通过凝血实验和凝血因子Ⅹ(FⅩ@活化实验检测(RGD@3-tTF融合蛋白的凝血活性,运用间接酶联免疫吸附试验(ELISA@方法分析其特异性结合肿瘤血管标志物整合素αvβ3的能力。结肠癌裸鼠模型分为3组(每组1只@,肿瘤组织分别用异硫氰酸荧光素(FITC@标记的(RGD@3-tTF、RGD-tTF融合蛋白、tTF进行荧光染色,免疫荧光实验分析融合蛋白在结肠癌裸鼠模型组织的定位。结果:(RGD@3-tTF融合蛋白保留了组织因子的凝血活性,在Ca2+存在时随着融合蛋白浓度的增加,凝血时间相应缩短,浓度为6μmol/L时,凝血时间为(9.96±0.56@min(与对照组比较,P0.05@。同浓度(RGD@3-tTF融合蛋白与整合素αvβ3的结合能力强于RGD-tTF(F=164.81,P<0.01@,当融合蛋白浓度为0.24μmol/L时,(RGD@3-tTF融合蛋白和RGD-tTF融合蛋白的A405nm分别为1.25和0.95。免疫荧光实验显示,(RGD@3-tTF融合蛋白富集于结肠癌裸鼠模型的肿瘤血管。结论:(RGD@3-tTF融合蛋白在保留组织因子凝血活性的同时通过高效、特异地结合肿瘤血管标志物整合素αvβ3,选择性地定位在结肠癌裸鼠模型的肿瘤血管上,为发展tTF作为效应因子的结肠癌分子靶向治疗奠定了基础

靶向血栓蛋白(RGD)_3-tTF与肿瘤血管标志物α_vβ_3特异性结合能力的研究

背景与目的:研究靶向血栓蛋白(RGD)3-tTF融合蛋白结合肿瘤血管标志物整合素αvβ3的能力,旨在探讨融合蛋白的RGD多肽数量和化学结构与其结合整合素αvβ3能力的关系及其意义。材料与方法:用3个串联的RGD多肽与截短组织因子(truncated tissue factor,tTF)合成融合基因(RGD)3-tTF,表达于大肠杆菌(E.coli)BL21(DE3),用镍柱纯化融合蛋白。通过凝血实验检测融合蛋白tTF组分的活性,运用间接酶联免疫吸附试验(ELISA)分析其特异性结合整合素αvβ3的能力,并与RGD-tTF融合蛋白的活性进行比较。结果:(RGD)3-tTF与RGD-tTF融合蛋白凝血活性相似(F=0.019,P>0.05),但(RGD)3-tTF融合蛋白特异性结合整合素αvβ3的能力明显升高(F=140.17,P<0.01)。当融合蛋白浓度为0.24μmol/L时,(RGD)3-tTF融合蛋白的OD405nm值是RGD-tTF融合蛋白的1.32倍(1.25/0.95)。结论:(RGD)3-tTF融合蛋白带有两个二硫键和3个RGD多肽,保留了组织因子凝血活性的同时,提高了与整合素αvβ3特异性结合的能力,为开展选择性肿瘤血管血栓靶向治疗的动物实验奠定了基础