厦门市某医院体检人群中有机氯农药暴露与胆石症发病的关联性研究

目的探讨厦门市第二医院体检人群中有机氯农药暴露与胆结石发生的关联及其发病危险因素。方法收集2015年2月-8月在医院健康体检人群中经B超确诊的新发胆囊结石患者100例,以同期参加体检的非胆囊结石者为对照,进行1∶2配比的病例对照研究。进行流行病学调查,采用气相色谱联用电子捕获器检测研究对象外周血中有机氯农药水平。应用多因素条件Logistic回归模型分析有机氯农药与胆囊结石发病的关系。结果病例组血清中α-HCH残留水平高于对照组,差异有统计学意义;Logistic回归分析非酒精性脂肪肝、2型糖尿病、血清α-HCH含量增高可能增加胆结石的患病危险,OR值及95%CI分别为5.134(1.952~13.502)、4.754(1.849~12.220)和1.357(1.094~1.854)。结论环境有机氯农药暴露可能是胆囊结石病发生的危险因素。厦门市科技计划项目(3502Z20163006)；厦门市集美区科技计划项目(20142C01)；厦门大学校长基金(20720152012)

GaAs/GaAlAs量子阱激子能量调谐的新方法

用分子束外延技术(MBE)在GaAs量子阱中嵌入InAs亚单层，可以有效地改变量子阱的激子能量，从而达到波长调谐的目的。激子能量的调谐范围取决于量子阱宽度，并和InAs层厚度有关。利用有效质量近似，计算给出了能量调谐曲线，结果与实验符合较好。该文给出的结果提供了一种改变量子阱发光器件波长的新方法

半导体纳米柱阵列结构的制作方法

一种半导体纳米柱阵列结构的制作方法，包括如下步骤：步骤1：在一半导体衬底上生长铝层；步骤2：对铝层进行阳极氧化，形成孔洞由表面直达半导体衬底，形成多孔氧化铝膜；步骤3：在多孔氧化铝膜的表面淀积金属，在多孔氧化铝膜的孔洞内形成金属点；步骤4：将多孔氧化铝膜湿法腐蚀掉，从而在半导体衬底上形成金属点阵列；步骤5：以金属点阵列为掩膜对半导体衬底进行刻蚀，去掉金属点阵列，在半导体衬底上形成半导体纳米柱阵列

Concentrations and distributions of Cu,Pb,Zn,Cd in surface sediments from Xiamen Jinmen sea area

1995年 1 0月调查研究了厦门 金门海域表层沉积物中重金属Cu、Pb、Zn、Cd的含量 ,Cu、Pb、Zn、Cd的平均浓度分别为 1 6 .6、5 2 .6、1 0 4、0 .2 0 5 (× 1 0 -6m/m ,干重 )。根据底质标准 ,Pb、Zn明显超标。从平面分布看 ,厦门岛南部海区(XJ1～XJ4号站 )的重金属含量高于北部海区 (XJ5～XJ7号站 ) ,北部海区又高于东部海区 (XJ9、R1、R2号站 ) ,尤其是南部海区的XJ1、XJ2、XJ3号站其含量明显较高。这一分布特征表明除了九龙江河流对该海域的贡献外 ,西海域的输入也是一个重要的因素。位于东部海区的XJ9、R1、R2号站 ,从XJ9至较靠近金门的R1、R2号站 ,重金属Cu、Pb、Zn、Cd的含量略有回升 ,其来源有待于进一步分析探讨。The concentrations of heavy metal Cu, Pb, Zn, Cd in surface sediments of Xiamen Jinmen sea area were investigated in Oct., 1995,whose mean concentrations were 16.6, 52.6, 104, 0.205 (×10 -6 m/m dry wt.) respectively. And those of Zn and Pb exceeded over the value of assessment criteria. For the plane distributions, the concentrations of Cu, Pb, Zn, Cd in the southern sea area (XJ1～XJ4 stations) were the highest, and those in the northern sea area (XJ5～XJ7 stations) were the second and those in the eastern sea area (XJ9, R1, R2 stations)were the lowest in Xiamen Jinmen sea area. Especially,the concentrations of Cu, Pb, Zn, Cd in the southern sea area (XJ1～XJ3stations) obviously higher than those of other stations, suggesting that input from the western Xiamen sea area was an important factor except the contribution from Jiulongjiang River to the sea area. From station XJ9 to R1 , R2, the concentrations of Cu, Pb, Zn, Cd had a slight increasing trend, and the sources of Cu,Pb,Zn,Cd in the eastern area would remain to be further probed.厦门市科委资助的两岸合作项

生物质多元醇选择性催化氢解制小分子二元醇研究进展

乙二醇、1,2-/1,3-丙二醇等小分子二元醇在精细和有机化工、生物医药等领域应用广泛。与石化路径相比,以可再生的生物质多元醇(丙三醇、山梨醇/木糖醇)为原料选择性催化氢解制取上述小分子二元醇具有过程简单、绿色高效等显著优势,已成为生物质催化转化的研究热点。本文综述了典型生物质多元醇山梨醇/木糖醇和丙三醇选择性催化氢解为乙二醇、1,2-/1,3-丙二醇等小分子二元醇,重点阐述了丙三醇选择性氢解制1,2-丙二醇、1,3-丙二醇和山梨醇/木糖醇选择性氢解制小分子二元醇的催化剂体系和反应机理,并对该领域的发展前景作了展望,提出开发高效稳定的催化剂体系和工艺是未来的研究重点

人造油體抗原展現系統

本發明係關於一種人造油體抗原展現系統,其特徵在於利用載體蛋白攜帶抗原物質,並鑲嵌於脂溶性顆粒中,而將抗原物質展現於脂溶性顆粒表面,提供作為抗體製備之外來抗原。本發明亦包含該人造油體抗原展現系統之製備方法,以及其用於疫苗製備之用途

Residue levels of persistent organochlorine pesticides and polychlorinated biphenyls in shellfish samples from eastern Xiamen Island and Minjiang Estuary

1 995～ 1 996年间 ,在厦门岛东部和闽江口沿岸养殖区的 7个站点采集了贝类样品 .样品先去壳匀浆 ,再经冷冻干燥、萃取浓缩和净化分离后 ,用GC法分析测定其六六六 (HCHs)、滴滴涕 (DDTs)和多氯联苯 (PCBs)的含量 .厦门岛东部HCHs、DDTs和PCBs的含量范围分别为 0 .1 8～ 34 5,75.2～ 2 1 43,ND 2 34ng/g干重 ;闽江口分别为ND - 5.0 7,2 1 .5～ 2 396 ,ND - 6 .78ng/g干重 .结果表明 ,贝类样品的有机氯污染物含量因不同采样地点、不同生物种类及不同采样时间而异 ,但总体上高于沉积物 ,牡蛎对DDT的富集尤为显著 .本文除了对调研区经济贝类的HCHs、DDTs和PCBs含量与组成分布进行分析评价 ,还就海区有机氯污染生物监测的可行性、经济贝类的食用卫生水平等问题作了探讨 .Shellfish samples were collected from 7 stations set in the coastal cultivating areas of eastern Xiamen Island and Minjing Estuary during 1995～1996. The samples were shelled and blended to paste, then freeze dried, extracted, concentrated, cleaned up and fractionated successively, afterward were analyzed for HCHs, DDTs and PCBs by GC. Concentration ranges of HCHs, DDTs and PCBs in the survey area of eastern Xiamen Island were 0.18-345, 75.2-2143 and ND-234 ng/g dry wt., respectively; those for Minjiang Estuary were ND-5.07, 21.5 -2 396 ND-6.78 ng/g dry wt., respectively. The results showed that the concentrations of organocholorine pollutants in shellfish samples varied with the sampling locations, time of collection and organism species, but were generally higher than those in sediments, especially for oyster. The concentrations and compositions of HCHs, DDTs and PCBs in the economic shellfish collected from the coastal cultivating areas of east Xiamen Island and Minjiang Estuary were analyzed and evaluated, besides, the feasibility of monitoring organochlorine pollutants using marine organisms, the hygienic level of the edible economic shellfish and so on were discussed

Advances in Polyols Production by Catalytic Hydrogenolysis of Cellulose

Due to climate and environment problems posed by use of fossil resources, developing advanced technologies for sustainable production of value added chemicals from renewable biomass is of scientific and practical importance. Among those, polyols producti

Concentrations and Distributions of Cu,Pb,Zn,Cd in Surface Sediments of Waters and Bivalves of Aquatic Areain Minjiang Estuary and Mazu

１９９５ 年１０ 月和１９９６ 年４ 月调查研究了闽江口－马祖海域表层沉积物中重金属Ｃｕ，Ｐｂ，Ｚｎ，Ｃｄ 的含量．结果表明：９５ 年１０ 月所采集的表层沉积物样品重金属Ｃｕ，Ｐｂ，Ｚｎ，Ｃｄ 的平均浓度分别为２６．６，３６．７，９８．７，０．１４４ ｍ ｇ／ｋｇ；而９６ 年４ 月Ｃｕ，Ｐｂ，Ｚｎ，Ｃｄ 的平均浓度则分别为２７．９，４３．７，１００．３，０．１６５ ｍ ｇ／ｋｇ，两航次的测定结果比较相近，根据底质评价标准，Ｐｂ，Ｚｎ 明显超标．两航次Ｃｕ，Ｐｂ，Ｚｎ，Ｃｄ 含量的峰值出现在闽江口的ＭＪ６ 测站，从ＭＪ６ 测站往外海方向的ＭＪ５、ＭＪ８ 测站呈明显下降趋势，但至较靠近马祖的ＭＪＲ１、ＭＪＲ２ 测站又有所回升，说明ＭＪＲ１、ＭＪＲ２ 这两个测站的重金属可能来自闽江口与马祖两方．还对沿岸养殖区获得的生物样中重金属Ｃｕ，Ｐｂ，Ｚｎ，Ｃｄ 的含量及其与沉积物的对比进行了分析讨论，并就生物种类及其生长周期等问题作了初步探讨．The concentrations of Cu,Pb,Zn,Cd in surface sediments of Minjiang Mazu Waters were investigated during Oct., 1995 and Apr., 1996. The mean concentrations of Cu,Pb,Zn,Cd were 26.6, 36.7, 98.7, 0.144 mg/kg, respectively in Oct., 1995 and those in Apr., 1996 were 27.9, 43.7, 100.3, 0.165 mg/kg, respectively; the concentrations of Zn and Pb exceeded the value of assessment criteria. For the surface distributions, the highest of Cu,Pb,Zn,Cd were found at station MJ6 in Minjiang River estuary during two cruises. From station MJ6 to stations MJ5 and MJ8 near the open sea, the concentrations had a decreasing trend and elevated at stations MJR2 and MJR1 which are close to the Mazu area, suggesting that Cu,Pb,Zn,Cd at stations MJR1 and MJR2 may come from both the Minjiang river and Mazu area. The concentrations of Cu,Pb,Zn,Cd in bivalves of aquatic area in Minjiang Estuary were investigated and compared with the surface sediments. The kinds and periods grown of bivalves are preliminarily discussed.福建省科委资助!两岸合作项目（无编号