Analysis of Status and Influence Factors of Anticoagulant Therapy for Inpatients with Nonvalvuiar Atrial Fibrillation

目的探讨非瓣膜病心房颤动住院患者抗凝治疗情况,并分析其临床影响因素。方法方便选取该院2010年9月—2013年10月期间收治的230例非瓣膜病心房颤动住院患者,依据2006年ACC/AHA/ESC房颤抗凝管理指南分为低危组、中危组以及高危组,分析其抗凝应用情况。结果房颤患者共221例,未根据指南抗凝的患者有174例,根据指南抗凝的患者有47例。结论当前该院基层医院住院的非瓣膜病心房颤动住院患者中,多数未接受指南推荐的抗凝剂治疗,尤其对于房颤脑卒中高危患者,更需要临床指南推荐。Objective To discuss the status of anticoagulant therapy for inpatients with nonvalvuiar atrial fibrillation and analyze its clinical influence factors. Methods 230 cases of inpatients with nonvalvuiar atrial fibrillation admitted and treated in our hospital from September 2010 to October 2013 were selected and divided into the low-risk group, average-risk group and high-risk group according to the ACC/AHA/ESC atrial fibrillation anticoagulation manage guide in 2006, and the application conditions were analyzed. Results In the 221 cases of patients with atrial fibrillation, 174 cases of patients were not according to the guide for anticoagulation and 47 cases were according to the guide for anticoagulation. Conclusion At present, most of the patients with nonvalvuiar atrial fibrillation hospitalized in the primary hospital have not accepted the anticoagulant therapy recommended by guide, and especially for the?high-risk atrial fibrillation stroke patients, the clinical guide recommendation is more needed

大学生体育锻炼与亚健康状态的相关性研究

目的探讨体育锻炼与亚健康的相关性。方法采用随机整群抽样的方法调查某大学515个学生,调查内容包括一般情况、体育活动参与情况和亚健康状态等。结果 (1)体育锻炼的运动量与亚健康状态各维度的得分之间呈负相关,运动量越大,亚健康各维度得分越低,且亚健康状态的发生率越低。(2)体育锻炼的各因素均与亚健康状态各维度的得分呈负相关;但运动的频率对亚健康状态各维度得分的影响最大。结论体育锻炼能够有效预防和健康亚健康状态的发生,且运动频率的作用最大

Research on construction and application of medical decision support system

目的:针对医院决策手段不丰富的现状,构建一套智能辅助决策系统为医院管理决策提供支持。方法:基于医院现有医疗数据,利用数据仓库、数据挖掘、联机分析处理等技术进行数据分析,构建智能知识库,将数据转化为用于辅助的知识决策,形成一体化的智能决策平台。结果:该决策支持系统能够帮助医院决策者更有效作出决策,提高了决策者的工作效率。结论:该决策系统具有较好的应用前景,适合在各医院推广应用。Objective To develop an intelligent decision support system for hospital decision-making.Methods Based on the existing medical data in the hospital, such technologies as data warehouse, data mining and online analytical processing were used for analyzing data and constructing intelligent knowledge base and integrated intelligent decision-making platform.Results The system might help the hospital administrator in decision making.Conclusion The decision support system is worthy popularizing in the hospital.南京军区重点项目(11Z023); 漳州市自然科学基金项目(Z2011009

Data-driven Health Status Prediction of the Hydraulic Turbine Governing System

水轮机调速系统是水轮发电机组的关键控制系统。运用故障树与专家系统相结合的方法对调速系统可能发生的故障进行诊断,并基于历史数据,挖掘与故障相关的可能因素,对专家系统无法解决的故障进行分析,构建了基于数据驱动的水轮机调速系统健康状态预测系统。The hydraulic turbine governing system is the key control system of the hydro-turbine generator unit. In this paper,the fault tree method and the expert system are combined to predict the potential faults of the governing system.Based on the historical data,a data-driven health status prediction system is developed for the hydraulic turbine governing system to detect the possible factors of the faults and analyze the unsolved faults

福建省高校高级知识分子亚健康状况调查分析与对策

目的通过了解福建省高校高级知识分子亚健康相关状况,进一步揭示影响他们身心健康的原因和需求,探讨改善该人群健康状况的策略。方法采用整群抽样的方法对我省15所本科院校在职的高级知识分子及科研人员2 454名教师进行问卷调查,并进行统计学分析。结果亚健康者935人,检出率38.10%,其中副高职称者健康状况比正高职称者差。结论我省高校高级知识分子的健康状况较差,应引起各高校的重视。福建省教育厅基金资助项目(JA08065S

Synthesis of Compact ZSM-5 Zeolite Membrane by Adding the Promoter NaCl

[中文文摘]报道了一种添加氯化钠低温条件下合成出具有纳米尺寸的ZSM 5分子筛 ,并以其为晶种预吸附在多孔氧化铝载体上 ,再通过添加成膜促进剂氯化钠二次水热合成制备出高度致密ZSM 5分子筛膜的新方法 .通过考察添加的钠离子浓度对成膜的影响 ,认为在一定浓度范围内钠离子能够促进成膜 .SEM结果也验证了这一结论 ,分子筛膜主要是由孪生聚晶分子筛组成 .渗透结果显示 ,当添加量为x =10 0 (Al2 O3 ∶84SiO2 ∶10Na2 O∶xNaCl∶15TPABr∶3 5 0 0H2 O)时 ,在室温和 0 .1MPa的条件下 ,H2 /C3 H8的理想选择性最大值 2 3 .7,温度提高到 2 0 0℃时的选择性下降为 9.4,但仍然高于努森扩散值 (4 .69) ,表明该膜具有高度的完整性。[英文文摘]The compact ZSM-5 membranes was synthesized on porous alumina substrates by pre-coating nanosized ZSM-5 seeds and then employing the twice hydrothermal synthesis with adding the promoter NaCl. Effect of Na + concentration on the formation of membrane was investigated in this work, indicating that adding a certain mount of NaCl can boost the growth of zeolite crystals on the substrates, thus forming the compact membrane consisted of highly intergrown crystals. The separating performance of zeolite membranes indicated that using a mixture with a composition of Al2O3∶84SiO2 ∶10Na2O∶100NaCl ∶15TPABr∶3500H2O as synthesis gel , the ideal selectivity of H2/ C3H8 could reach a maximum value of 23. 7 at room temperature and pressure difference of 0. 1 MPa , and the permselectivity decreased to 9. 4 at testing temperature of 200 ℃, which is still higher than the corresponding Knudsen diffusion value (4. 69) , suggesting that the membrane synthesized by this method was defect-free.国家重点研究发展规划基金 (No.G1999022401 ); 国家自然科学基金(No.K16161 )资助项目

Relationship between BMI,WHR and brachial arterial vasodilation function of middle-aged patients with impaired glucose tolerance

探讨体重指数(bMI)、腰臀比(WHr)与中年糖耐量减低(IgT)者血管内皮功能的关系。行标准75g口服葡萄糖耐量试验(75gOgTT),诊断为IgT者101例,年龄在45-59岁。对研究对象检测bMI、WHr、肱动脉血流介导的内皮依赖性血管舒张功能(以△dIA-P%表示)、硝酸甘油介导的非内皮依赖性血管舒张功能(以△dIA-n%表示)、C-型利钠肽(CnP)、内皮素-1(ET-1)、OgTT2H血糖、空腹血糖及胰岛素,计算胰岛素抵抗指数(HOMA-Ir),并进行统计学分析。bMI、WHr与空腹血糖、Og-TT2H血糖、空腹胰岛素、HOMA-Ir、ET-1、CnP、△dIA-P%具有相关性,而且bMI与△dIA-n%具有相关性。bMI正常、超重与肥胖三组比较,正常组与肥胖组之间ET-1、CnP、△dIA-P%、△dIA-n%、空腹血糖、OgTT2H血糖、空腹胰岛素和HOMA-Ir均具有显著性差异,而超重组与肥胖组之间ET-1、空腹血糖、OgTT2H血糖、空腹胰岛素、HOMA-Ir具有显著性差异。WHr正常与异常二组比较,空腹血糖、OgTT2H血糖、空腹胰岛素、HOMA-Ir、ET-1、CnP、△dIA-P%具有显著性差异。中年IgT者血管内皮功能、糖代谢及胰岛素敏感性受体脂含量、体脂分布的影响,bMI、WHr与血管内皮功能障碍、胰岛素抵抗、糖代谢异常之间存在相关性,而且二者与胰岛素抵抗、糖代谢异常的相关性较血管内皮功能障碍的相关性大,腹型肥胖是胰岛素抵抗的重要相关因素。The purpose of this study was to discuss the relationship between MI,WHR and vascular endothelium function of middle-aged patients with impaired glucose tolerance.101 persons diagnose4d as IGT,aged between 45-59 were detected on BMI,WHR,△Dia-P%,△Dia-N%,CNP,ET-1,OGTT2h glucose,fasting blood glucose and insulin after taking 75gOGTT.HOMA-IR was caculated and statistics was analyzed.The result showed that BMI and WHR had relationship with BMI,WHR,△Dia-P%,ET-1,OGTT2h glucose,fasting blood glucose,fasting insulin,CNP and HOMA-IR,and BMI had relationship whith △Dia-N%.Compared with those of the overweight group and obesity group,ET-1,CNP,△Dia-P%,△Dia-N%,fasting blood glucose,OGTT2h glucose,fasting insulin and HOMA-IR were different between the normal group and the obesity group.ET-1,fasting blood glucose,OGTT2h glucose,fasting insulin and HOMA-IR were significantly different between overweight group and obesity group.The comparison of fasting blood glucose,OGTT2h glucose,fasing insulin,HOMA-IR,ET-1,CNP and △Dia-P% were different between normal WHR and abnormal WHR.It was concluded that the percentage of body fat and distribution of body fat influenced vascular endothelium function,glucose metabolism and insulin sensitivity of middle-aged patients with impaired glucose tolerance.BMI and WHR were related to vascular endothelium dysfunction,insulin resistance,abnormal glucose metabolism.福建省自然科学基金资助项目(X0850028/2008J0272

In situ Time-resolved FTIR and Raman Characterizations of the Partial Oxidation of Methane to Synthesis Gas over Ir/SiO_2 Catalyst

[中文文摘]采用原位时间分辨红外光谱和原位显微Raman光谱技术对Ir/SiO2 上甲烷部分氧化 (POM)制合成气反应的初级产物和反应条件下催化剂表面物种进行了跟踪考察 ,实验结果表明 ,在H2 预还原的新鲜Ir/SiO2 表面 ,CO是V(CH4)∶V(O2 )∶V(Ar) =2∶1∶45混合气反应的初级产物 ,因而甲烷的直接氧化过程是CO生成的主要途径 ;而在稳态反应条件下 ,CO生成的途径可能主要来自CO2 和H2 O与催化剂表面积碳物种 (CHx)和 /或CH4的反应 .催化剂上生成的积碳可能是导致稳态条件下Ir/SiO2 上POM反应机理不同于H2 预还原的新鲜催化剂的主要原因。[英文文摘]In situ time-resolved FTIR and in situ microprobe Raman spectroscopies were used to follow the primary products as well as the surface and gas phase species formed during the reaction of partial oxidation of methane (POM) to synthesis gas over Ir/SiO 2 catalyst. The results suggested that direct oxidation of CH 4 to CO is the dominant pathway of POM reaction over the freshly reduced Ir/SiO 2 catalyst, while the dominant schemes of CO formation over the catalyst under the steady state reaction condition are probably via the reactions of CO2 and H2O with the deposited carbon species (CHx) and/ or CH4 . The mechanistic difference between the POMto synthesis gas over freshly reduced Ir/ SiO2 catalyst and the catalyst under the steady state reaction may have resulted from the formation of significant amount of deposited carbon species in the latter system.国家重点基础研究发展规划 (No.G1999022408); 国家自然科学基金(No.20021002)资助项目

Synthesis of compact ZSM-5 zeolite membrane by adding the promoter NaCl

The compact ZSM-5 membranes was synthesized on porous alumina substrates by pre-coating narrosized ZSM-5 seeds and then employing the twice hydrothermal synthesis with adding the promoter NaCl. Effect of Na+ concentration on the formation of membrane was investigated in this work, indicating that adding a certain mount of NaCl can boost the growth of zeolite crystals on the substrates, thus forming the compact membrane consisted of highly intergrown crystals. The separating performance of zeolite membranes indicated that using a mixture with a composition of Al2O3: 84SiO(2): 10Na(2)O: 100NaCl: 15TPABr: 3500H(2)O as synthesis gel, the ideal selectivity of H-2/C3H8 could reach a maximum value of 23.7 at room temperature and pressure difference of 0.1 MPa, and the permselectivity decreased to 9.4 at testing temperature of 200 degreesC, which is still higher than the corresponding Knudsen diffusion value (4.69), suggesting that the membrane synthesized by this method was defect-free