On the Protection of Property of Real Buyer In a Dual Buying-and-selling By Means of Deceptive Mortgage Loan

我国的不动产物权的变动主要以债权合意并进行登记方发生法律效力，买受人自签订商品房买卖合同到取得所有权登记存在一定的时间差。而房地产业在我国是一项新兴行业，相关法律法规的制定滞后于房地产业的迅猛发展，再加上经济社会中经济人的逐利本质，房地产开发商不顾信用而一房两卖、甚至一房数卖，损害买受人权利的现象曾时有发生。在实践中，商品房二重买卖的情形多种多样，情况各有不同。其中一种特殊的商品房二重买卖，也就是通常所称的“假按揭”现象较为普遍。所谓“假按揭”现象，即开发商以“一房两卖”的形式与特定关系人串通签订商品房买卖合同，并办理按揭贷款以套取银行借款，该买受人并不真正以取得房屋所有权为目的。此后，开发商...In our country, the changes of in rem of real estate is not legally effective unless having reached an consensus on creditor’s right and the r finished the registration. There is time lapse between the buyer having signed the commodity housing buying-selling contract and the registration of the ownership of the commodity housing. The real estate sector is a fresh sector in China, relevant laws ar...学位：法律硕士院系专业：法学院法律系_法律硕士(JM)学号：X200512011

Exploration and Application of Method to Pre-Process Filed Flight Plan Message

当前民航系统使用的AFTN（AeronauticalFixedTelecommunicationNetwork： 航空固定电信网）报文存在格式、内容、数据不规范的问题，致使FDP系统（Flight DataProcessingSystem：飞行数据处理系统）报文识别率不高，加重了ATC（Air TrafficControl：空中交通管制）管制员的工作负荷。本文针对FPL报（FiledFlight PlanMessage：领航计划报）进行预处理，首先接收报文并对报文编组做规范性 判断，对于非规范性FPL报文，采用直接查询调用历史报文数据替代、数据字典 数据替代、根据规范直接纠正等方法...The current aviation system uses the AFTN messages’ exist format, content, data irregularities, result in low telegram recognition rate of FDP Systems, and increased the ATC controller’ workload. The paper here aimed at pre-processing the FPL Message according to FPL message standard, at first, system judged validity of FPL after receiving, for nonstandard message, directed to querying histori...学位：工程硕士院系专业：信息科学与技术学院计算机科学系_计算机技术学号：X200622102

TGF-β1 induces activation of HSC-T6 cells and epithelial-mesenchymal transition in rats

目的探讨转化生长因子-β1（TGF-β1）在大鼠肝星状细胞系（HSC-T6）活化及上皮间质转换（EMT）中的作用。方法体外培养HSC-T6，用MTT法筛选TGF-β1对HSC-T6作用的最佳浓度；用10μg／L TGF-β1处理HSC-T624h，相差倒置显微镜下观察细胞形态改变，免疫荧光染色法检测细胞骨架结构F-actin蛋白的表达，RT-qPCR法检测肌动蛋白α-SMA及代表上皮间质转换的神经黏附素（N-cadherin）、波形蛋白（vimentin）和上皮黏附素（E-cadherin）基因表达；用不同浓度（0、5和10μg/L）的TGF-β1处理HSC-T624h，Western blot检测α-SMA、N-cadherin、vimentin和E-cadherin蛋白表达。结果10μg/L TGF-β1干预HSC-T624h有最好的细胞存活率；TGF-β1刺激HSC-T6后，细胞拉伸，伪足增多呈星形，细胞间连接疏松，呈显著活化状态；F-actin聚集形成应力纤维丝，沿细胞长轴分布；实验组α-SMA mRNA及vimentin mRNA的表达量明显高于对照组（P〈0．05），而E-cadherin mRNA的表达量明显降低（P〈0．05）；在不同浓度的TGF-β1呈剂量依赖性致α-SMA及N-cadherin和vimentin的蛋白表达量增多，而E-cadherin的蛋白表达量减少。结论TGF-β1可诱导HSC-T6活化及上皮间质转换。Objective To observe the effect of TGF-β1 on activation and epithelial mesenchymal transition （EMT） in rat hepatic stellate cell-T6. Methods Adopt the MTT method to screen the optimum concentration of TGF-β1 in vitro HSC-T6 cultured. After the HSC-T6 stimulation by TGF-β1 of 10 μg/L for 24 hours, the morphology of the cells was observed under inverted phase contrast microscope, the expression of F-actin which on behalf of cotoskeletal structure was detected by immunofluorescence staining; the expression of α-SMA and N-cadherin, vimentin, E-eadherin was measured by RT-qPCR ; The changes of α-SMA, N-cadherin, vimentin and E-eadherin were assessed by Western blot after different concentrations （0,5 and 10 μg/L） of TGF-β1 interventing HSC-T6 for 24 h. Results The optimal cell survival rate was recorded when 10 μg/L TGF-β1 dealt with cells for 24 h. After HSC-T6 were treated with TGF-β1 ,cells stretched, pseudopodia increased and turn into stellate, ceils connections were looser, so that represented a significantly activated state. F-actin filaments gathered to form stress and distributed along the long axis of the cells ; The expression of α-SMA mRNA and vimentin mRNA in experimental group was significantly higher while E-cadherin mRNA was obviously lower than the control group （P〈 0. 05）. TGF-β1 made the protein expression of α-SMA and N-cadherin, vimentin in dose-dependent increased while E-cadherin was decreased.Conclusions TGF-β1 may induce activation and epithelial-mesenchymal transition of HSC-T6.福建省科技计划（2015Y01010224）;福州市科技计划（2014-S-137-1

基于栈自编码器的图像分类器

图像分类问题包含两个重要的部分:特征提取器和分类器.多年来研究人员一直将精力投入到特征表示中,对于分类器却仅进行局部调参.基于一个性能优异的分类器与特征表示对图像分类系统同等重要的思想,提出了基于卷积特征的栈自编码器(stacked autoencoder on convolutional feature maps,SACF)的分类系统,并在数据集CUB-200和VGGflower上进行了实验,对比了SACF与基于卷积特征和多层感知机的卷积神经网络(CNN)分类系统的分类效果,实验结果表明SACF具有更优的分类效果.国家自然科学基金(61572409,61571188,61202143);;福建省自然科学基金(2013J05100);;中国乌龙茶产业福建省2011协同创新中心项目(闽教科[2015]75号);;福建省教育厅A类科技项目(JA13317

智能化门诊药房存在的问题及其改进措施

门诊药房是医院与病人交流的窗口,处方调剂是病人在医院就诊的最后环节,发药速度快慢对病人及其家属的就医满意度产生直接影响[1]。为创造良好的工作环境、提高药房管理水平[2]、确保病人用药安全[3],解放军第一七五医院于2015年8月底启用了智能化门诊药房。该药房的引进给药师带来很多便利,同时也对药房工作模式的改进提出了要求。作者从自身工作出发,结合医院现状及智能化门诊药

端面泵浦Nd∶YAG连续输出1052nm波长激光器

设计了一个简单紧凑的1052nm波长激光器。首次利用激光二极管(LD)端面泵浦Nd∶YAG晶体,使用镀有高度选择性介质膜的反射镜产生该波段的激光。激光阈值为0.3W,当808nm波长泵浦光功率达到18W时产生了3.5W的1052nm波长激光输出。光-光转换效率为20%,输出激光功率波动不超过3%

福建外来船舶压舱水中浮游植物种类组成与丰度及其影响因素的初步研究

2006~2008年间对进入福建沿海4个主要港口的12艘国际航船所携带的压舱水进行浮游植物种类组成和丰度分布的调查.此调查共检测出浮游植物7个门86属239种(含变种和变型),77μm孔径网滤样和20μm孔径网滤样的平均藻类丰度分别为1.2×102cells/dm3(变动在0~9.1×102cells/dm3间)和3.4×103cells/dm3(变动在0~3.0×104cells/dm3间).同时对其中6艘船舶的压舱水样品用f/2培养基培养,共有13种硅藻和1种甲藻被成功培养.文中还分析了压舱水中浮游植物丰度与盐度、水龄的关系,并结合历史资料讨论了压舱水里各类浮游植物的分布

中国东南沿海港口外轮压舱水生物的调查

随机选取东南沿海港口的17艘外来船舶(含8条集装箱船和9条散货船)作为监测对象,进行压舱水浮游植物及动物的物种鉴定和丰度测定,并对监测数据进行统计学分析。检出分属于7个浮游植物门类和5个动物门类的309种外来压舱水生物(包括60种赤潮生物)。外轮压舱水生物的分布及生存状态与水样的水龄和盐度相关。船舶压舱水排放是大家熟知的外来水生生物入侵的主要媒介。本调查结果表明,中国东南沿海外来散货船的压舱水排放所具的潜在生物入侵风险比集装箱船更应受关注

Efficacy, Safety, and Immunogenicity of an Escherichia coliProduced Bivalent Human Papillomavirus Vaccine: An Interim Analysis of a Randomized Clinical Trial

HPV是一种常见的生殖道感染病毒，高危型HPV持续性感染能够导致几乎所有的宫颈癌，其中HPV 16型和18型危害最大，可导致约70%的宫颈癌。预防性HPV疫苗有望减少甚至最终消灭由疫苗型别导致的宫颈癌，降低HPV相关的疾病负担。该研究是在全国4个中心5个现场的18-45岁健康女性中进行的多中心、随机、双盲、对照（戊肝疫苗）的三期临床试验，该研究结果证实我校自主研发的双价人乳头瘤病毒疫苗（大肠杆菌）具有良好的安全性、免疫原性和免疫持久性，可有效地预防HPV 16型和/或18型相关的宫颈高度癌前病变及持续性感染。 该论文报告了我校和厦门万泰沧海生物技术有限公司自主研发的双价人乳头瘤病毒疫苗（大肠杆菌）三期临床试验的期中分析结果。这是第一个进入临床试验并提交药品注册申请的国产人乳头瘤病毒疫苗（HPV疫苗），有望成为世界上第四个上市的HPV疫苗，受到世界卫生组织和盖茨基金会等国际组织的高度关注。 中国医学科学院肿瘤医院乔友林教授、我校吴婷教授、广西壮族自治区疾病预防控制中心李荣成主任医师、江苏省疾病预防控制中心胡月梅主任医师、北京大学人民医院魏丽惠教授、中国食品药品检定研究院李长贵研究员、中国医学科学院肿瘤医院陈汶教授为该论文的共同第一作者，我校张军教授、夏宁邵教授和中国医学科学院肿瘤医院乔友林教授为该论文的共同通讯作者。【Abstract】Background The high cost and insufficient supply of human papillomavirus (HPV) vaccines have slowed the pace of controlling cervical cancer. A phase 3 clinical trial was conducted to evaluate the efficacy, safety and immunogenicity of a novel Escherichia coli-produced bivalent HPV-16/18 vaccine. Methods A multi-centre, randomized, double-blind trial started on November 22, 2012, in China. In total, 7372 eligible women aged 18-45 years were age-stratified and randomly assigned to receiving 3 doses of the test or control (hepatitis E) vaccine at months 0, 1 and 6. Co-primary endpoints included high-grade genital lesions and persistent infection (over 6 months) associated with HPV-16/18. The primary analysis was performed on a per-protocol susceptible population of individuals who were negative for relevant HPV type-specific neutralizing antibodies (at day 0) and DNA (at day 0 through month 7) and who received 3 doses of the vaccine. This report presents data from a pre-specified interim analysis used for regulatory submission. Results In the per-protocol cohort, the efficacies against high-grade genital lesions and persistent infection were 100.0% (95% confidence interval [CI] = 55.6% to 100.0%, 0/3306 in the vaccine group vs. 10/3296 in the control group) and 97.8% (95% CI = 87.1% to 99.9%, 1/3240 vs. 45/3246), respectively. The side effects were mild. No vaccine-related serious adverse events were noted. Robust antibody responses for both types were induced and persisted for at least 42 months. Conclusions The Escherichia coli-produced HPV-16/18 vaccine is well tolerated and highly efficacious against HPV-16/18 associated high-grade genital lesions and persistent infection in women.This work was supported by grants from the Chinese National High-tech R&D Program (863 program, 2012AA02A408), the Chinese National Major Scientific and Technological Special Project for “Significant New Drug Development” (2018ZX09308010 and 2012ZX09101316), the National Natural Science Foundation of China (81673240 and U1705283), the Fujian Provincial Major Scientific and Technological Project (2015YZ0002), the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (CIFMS, 2017-I2M-B&R-03, and 2016-I2M-1-019) and Xiamen Innovax. 该研究获得了国家高技术研究发展计划（863计划）、新药创制国家科技重大专项、国家自然科学基金、福建省科技重大专项、中国医学科学院医学与健康科技创新工程基金以及厦门万泰沧海生物技术有限公司的资助

会话中的演绎与角色扮演 ：从会话分析的角度探究其运作模式 = Enactment and role-playing in conversation : a study of the operations through conversation analysis

本文将探讨的是一个在日常会话中常用的会话模式。这个模式在本文的研究里将暂以“演绎”为名。在这样的过程中，一个谈话者会开始扮演谈话参与者们共同拟定的场景中的一个角色。当他完成自己的话轮之后，听话人便会在其话轮或之前的话轮里没有进一步阐述所拟定的场景的情况下，使用与第一个说话人相同的方式，扮演场景中相同或不同角色的方式来进行自己的话轮，以回应第一个说话人并延续他所开始叙述的场景或情节。谈话参与者们准确地揣摩和延续演绎的场景，说明他们即使没有互相告知演绎场景的内容，却仍可以对其有充分的理解。本文从会话分析的角度，着重于对演绎过程中的行为和运作模式给予描述，也会探讨三种不同的预设演绎场景的方式。这是因为场景的预设是演绎得以进行的先决因素。本文也会尝试分析谈话参与者在会话中采用演绎，而选择不将其所呈现的主题和观点直言的目的。这同时也是作为演绎的功能所在。This article examines a commonly used practice in daily conversation, tentatively termed “enactment” for this study. This practice is observable when a speaker acts out the role of a character in a specific and constructed scenario intended to be mentioned in his turn of speech. The other participants of the conversation will follow suit subsequently as a response to as well as continuation of the enactment started by playing the role of either the same or another character of that scenario the first speaker had during his turn. The point worth mentioning is that all participants of the conversation do not verbally communicate information of the scenario that is being constructed, yet they are able to display understanding of the unsaid through accurate interpretation and continuation of the scenario which the first speaker has started. Using conversation analysis, this article focuses on describing the actions and operations involved during an enactment. The various ways of presetting the scenario to be used by the participants as a prerequisite for the enactment will also be discussed. This article will then attempt to provide an account for participants to adopt this practice instead of telling the literal meaning of the theme and idea behind the enactment, which simultaneously serves as the function of the enactment.Bachelor of Art