Asymmetric Total Synthesis of Verrupyrroloindoline and the Exploration of Efficient Synthesis of Loline Alkaloid

天然产物全合成是有机化学中最为活跃、最具原动力的研究方向之一。发展高效、高选择性合成方法以减少合成步骤、降低成本和提高合成效率是当前有机合成的主要目标之一。 酰胺作为稳定的合成中间体被广泛应用于有机合成和药物化学。因此，发展通用、化学选择性的酰胺直接转化的方法十分重要。同时，课题组发展了DMDO引发的吲哚氧化、环氧开环环化、酰胺化一锅串联反应构建喹唑啉酮，该方法具有步骤经济性、原子经济性和无保护基合成的优点。 本论文结合两种高效的合成方法完成了verrupyrroloindoline的不对称全合成研究及发展了铱催化硅烷还原α-酯基叔酰胺叔酰胺为重要合成中间体烯胺酯方法；另外，基于环状烯醇硅...The total synthesis of natural products is a principal driving force for new chemical and biological discovery. Total synthesis projects often require a variety of reactions and intermittent tedious purifications, thus, which push the synthetic chemist to develop and perform highly efficient and selective synthetic methods aiming at designing and executing an efficient synthesis. Amides are stabl...学位：理学硕士院系专业：化学化工学院_有机化学学号：2052014115155

国外科技基础设施科技政策特点和制定流程分析

为探索如何最大限度地发挥战略规划的效用,通过分析国外科技基础设施战略规划在编制目的、范围和过程方面所表现出的特点与不足之处,对我国重大科技基础设施战略规划的制定提出思考和建议。</p

Preliminary studies on the scale insect pest of Pseudaulacaspis cockerelli in mangrove

首次发现陆生考氏白盾蚧严重为害潮间带红树植物秋茄。通过野外定位调查和室内饲养观察,研究其危害特征、种群分布、生殖力和自然死亡率。结果表明,考氏白盾蚧主要分布在秋茄叶片主脉两侧,叶背虫口数显著多于叶面(P<0.01),单叶虫口数多为1-50头,平均25.65头,最高418头;秋茄植株不同垂直空间层次的虫口密度无显著差异,但聚集度随垂直空间下降而增大;种群平均产卵量每雌52.22粒,自然死亡率69.35%,寄生蜂寄生是最主要的死亡因子,寄生率达34.23%;与几种陆生寄主植物相比,红树林考氏白盾蚧的种群密度、生殖力、叶最高虫口数均较高,该虫对潮间带生境及寄主秋茄具有适应性。The scale insect,Pseudaulacaspis cockerelli is an important pest for many kinds of plants for a long time in the land.In 2006,it was found firstly attacking the mangrove plant of Kandelia obovata in the tideland in Xiamen City,and had led to badly damages.Based on the field surveys and lab feeding,this paper dealed with its damage characteristic,population distribution,fecundity and natural mortality etc.The results showed that the scale insect mainly distributed on both sides of the midvien of K.obovata leaves,but the individual on the abaxial surface was significantly more than those on the adaxial surface(P<0.01).The individual number of one leaf mostly fluctuated from 1 to 50,and the average and tiptop numbers were 25.65 and 418,respectively.The pest population density had no remarkable discrepancies among different vertical spatial layer of K.obovata,however,its aggregating degree increased with falling of the layer.The population had an avarage fecundity of 52.22 each female and a high natural mortality of 69.53%.The main natural death factor were two species of parasites(Hymenoptera: Chalcididae),and their total parasitical ratio reached 34.23%.In the mass,the pest population density,fecundity and tiptop individual number of a leaf in the mongrove were all more than those in serval other host plants on land,which implied that this scale insect had a high adaptability to the habitat of tideland and the plant of K.obovata

Non-cyanide copper plating on steel substrate in alkaline citrate bath

以柠檬酸盐为配位剂,结合胺化合物为辅助配位剂,研究了钢铁基体上无氰镀铜工艺。探索了搅拌方式、温度、PH、铜离子质量浓度和添加剂质量浓度对镀层质量的影响以及该工艺抗fE2+、fE3+、zn2+、Sn4+等杂质的能力。试验结果表明,电流效率在90%左右,并随电流密度、温度和PH的提高而增大;镀液深镀能力达100%。通过极化曲线,解释了配位剂和添加剂的作用。The process of alkaline non-cyanide copper electroplating on steel substrate was studied using citrate as complexing agent and amine compound as assistant complexing agent.The effects of agitation mode, temperature, pH, copper ions concentration and additive content on deposit quality were discussed.The ability of bath to resist impurities such as Fe2+, Fe3+, Zn2+ and Sn4+ was revealed.The test results showed that the current efficiency is about 90% and is increased with increasing current density, temperature and pH.The throwing power of the bath is 100%.The action mechanisms of the complexing agents and additive were explained based on polarization curves.广东省教育部产学研结合专项资金项目(2006D90404019);福建省科技计划重点项目(2008H0086);国家自然科学基金项目(20873114