Preparation and study of an antioxidant phycocyanin/collagen composite hydrogel

The type I collagen extracted from Tilapia skin was mixed with Phycocyanin of different concentrations, and the composite hydrogel was prepared by self-assembly properties of collagen. The permeability, microscopic morphology, infrared spectrum, swelling rate and antioxidant of the composite hydrogel were investigated. Results show that permeability, microscopic pores and swelling rates of composite hydrogel increased significantly with increase of phycocyanin content. Infrared spectra showed that characteristic absorption peaks of these two proteins did not be destroyed by the preparation method. In the antioxidant experiment, composite hydrogel with excellent antioxidant capacity showed scavenging capacity of DPPH free radicals, hydroxyl radical

Advances and prospects in the research of aquatic collagen for medical applications

Collagen possesses superior properties,including low immunogenicity,good biocompatibility,biodegradability,hemostasis,and promotion of cell growth.Aquatic collagen has been widely investigated because of its increased safety.This paper explores the progress in the research of aquatic collagen for medical applications and provides a basis for future research work.</p

Research advances in the preventative and therapeutic effects of phycocyanin on oxidative stress-related diseases

Oxidative stress,which has attracted extensive research attention for over forty years,plays a crucial role in the occurrence and deterioration of various diseases.The oxidative stress resulting from harmful stimulation is related to many diseases,e.g.,atherosclerosis,hepatitis,pneumonia,Alzheimer's disease,and cataracts.In this study,oxidative stress alleviation is presented in a new form to realize the prophylaxis and therapy of the above diseases.Phycocyanin,a natural product extracted from algae,is often used in health products and food additives.Research has found that phycocyanin has a beneficial effect in preventive treatments in different ways,such as the elimination of free radicals and reduction of oxidative stress.Here,we review the important role of phycocyanin in the prevention and cure of oxidative stress-related diseases and discuss the prospects for its application,which provide a reference for phycocyanin use in the future

Protective effect of phycocyanin against oxidative damage induced by radiation

[Background] Phycocyanin (PC) is a pigment protein present in cyanobacteria, cryptophyta, etc. [Purpose] This study aims at the protective effect of phycocyanin on oxidative damage induced by irradiation by establishing injury mouse model by X-ray irradiation. [Methods] 72 C57 BL/6 male mice were randomly divided into normal control group, irradiation model group, PC pretreatment group and positive control group. The mice were continuously fed for 7 d. On the 8th day of intragastric administration, except for the normal control group, the rest of the mice were subjected to total body irradiation to a dose of 6 Gy for the preparation of radiation damage model. The plasma and tissues were collected at 1 d, 3 d and 7 d after irradiation, and the activities of antioxidant enzymes in plasma and liver were measured. The content of reactive oxygen species (ROS) in liver tissue was detected by dihydroethidium (DHE) staining. [Results] Phycocyanin increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) in the plasma of mice after irradiation, and increased the activity of SOD (p<0.05), decreased malondialdehyde (MDA) content (p<0.05), and reduced liver tissue ROS content (p<0.05). [Conclusion] The results show that phycocyanin can improve the antioxidant capacity of mice, reduce oxidative damage to the body caused by irradiation, and provide a better protective effect on irradiation injury of mice

荒漠地区公路建设环境保护与生态恢复技术

《荒漠地区公路建设环境保护与生态恢复技术》项目组通过资料收集、理论分析、室内外试验和工程实践,系统开展了荒漠地区公路建设与自然环境相互影响、荒漠地区公路建设的生态环境敏感性、荒漠地区公路建设环境保护与生态恢复技术集成以及典型区域公路建设环保与生态建设示范四方面研究,取得了如下主要创新性成果： 1．分析揭示了荒漠地区公路与环境的相互影响关系,建立了公路建设环境保护与生态恢复的基础平台。 2. 提出了荒漠地区公路路域生态功能重要性、环境敏感性和景观类型区划的原则与方法,建立了相应的区划体系。 3．构建了荒漠地区公路路域生态修复技术评价指标体系和评价数学模型。 4．提出了荒漠..

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel