63 research outputs found

    The Finite Groups With the Same Degree and the Prime Number of Non-linear Irreducible Characters

    Get PDF
    对于具有素数个非线性不可约特征标且它们的维数相等的有限群,我们给出一个分类.In this paper,we classify all the finite groups which have prime number of non-linear irreducible characters and whose degrees for these non-linear irreducible characters are equal.supportedbyNaturalScienceFoundationandGZ310ofSino-GermanyAcademicCenter

    养老机构老年人生活满意度影响因素的主成分logistic回归研究

    Get PDF
    目的分析养老机构内老年人生活满意度情况及其影响因素。方法采用整群随机抽样方法,在厦门市13家养老机构抽取230名老年人进行调查,了解养老机构老年人生活满意度状况,并利用主成分logistic回归分析其影响因素。结果获得有效问卷204份。调查显示厦门市养老机构内老年人生活满意度普遍较高。女性、年龄小、文化程度高、日常生活能力和健康自评效果好、与亲人相见频数高、对机构支持信任度高的老年人生活满意度相对较高。结论为提高养老机构老年人生活满意度,积极应对老龄化,老人应理性对待自身健康状况,积极面对生活;亲属应多去看望,给予老人更大的关爱和心理慰藉;养老机构也应大力提高其服务质量,丰富服务内容,给予老年人充分的物质、精神支持。国家自然科学基金(71403229,81573257

    基于Andersen模型的“医养结合“型机构养老需求的影响因素研究

    Get PDF
    目的了解老年人对\"医养结合\"型机构养老需求的现状及其影响因素,为构建多层级、持续性\"医养结合\"长期照护服务体系提供循证依据。方法采用多阶段抽样方法,抽取厦门市6个区,16个街道/镇,44个社区,3260名60周岁及以上老年人进行面对面问卷调查。基于Andersen理论模型,采用卡方检验分析人群分布差异,采用二元logistic回归分析方法从倾向性因素、使能因素、需要因素等方面分析老年人对\"医养结合\"型机构养老需求的影响因素。结果大多数老年人选择传统的居家养老(82.01%),仅有12.89%的老年人表示希望入住\"医养结合\"型养老机构。倾向性因素中,年龄越大、文化水平越高、居住在农村的老年人更倾向于选择医养结合养老模式,OR值均大于1(P<0.05);使能因素中,在婚、主要由配偶照护、经济状况越好的老年人倾向于医养结合式养老,OR值均大于1(P<0.01);需要因素中,老年人自理情况越差越倾向于入住\"医养结合\"型养老机构(P<0.01)。使能因素对模型的贡献度最大,对医养结合养老需求的影响最大。结论厦门市老年人对于\"医养结合\"机构养老模式的需求高于一般的机构养老需求。\"...国家自然科学基金项目(81573257);;\n福建省自然科学基金(2017J01133

    Preparation and evaluation of insulin thiolated hyaluronic acid nanoparticles in vitro

    Get PDF
    目的制备胰岛素巯基化透明质酸纳米粒(InSulIn THIOlATEd HyAlurOnIC ACId nAnOPArTIClES,InS-HA-CyS-nPS),考察纳米粒的理化性质。方法以合成的具有生物黏附性质的巯基化透明质酸作为载体,采用超声乳化法制备纳米粒,考察其外观、粒径、zETA电位、包封率、载药量,并进行其冻干制剂的冻干保护剂筛选。结果制备的InS-HA-CyS-nPS粒径均一,外观圆整;平均粒径为(178.5±0.8)nM,PdI为(0.214±0.013),zETA电位为-(38.47±0.46)MV,超滤离心法测定载药纳米粒的包封率为(48.85±0.66)%,载药量为(4.79±0.13)%;选择10%的甘露醇为冻干保护剂,复溶后得到具有蓝色乳光的粒径均一的纳米粒混悬液。结论巯基化透明质酸纳米粒是蛋白多肽类药物口服给药的潜在载体,为下一步研究胰岛素纳米粒在大鼠体内药效、药动学研究提供前提和基础。Objective To prepare insulin thiolated hyaluronic acid nanoparticles( Ins-HA-Cys-NPs) and study its physicochemical properties.Methods The Ins-HA-Cys-NPs was prepared by ultrasonic emulsifying method,and the properties of nanoparticles including morphology,mean diameter,Zeta potential,entrapment efficiency and drug loading efficiency were studied,as well as the cryoprotectant selection.Results The prepared nanoparticles was round in appearance and the mean diameter was( 178.5 ± 0.8) nm,the polydispersity index was( 0.214 ± 0.013) and the Zeta potential was-( 38.47 ± 0.46) mV,while the entrapment efficiency was( 48.85 ± 0.66) %,drug loading efficiency was( 4.79 ± 0.13) %; 10%mannitol as cryoprotectant provided uniform and well dispersed suspension of nanoparticles with blue opalescence after redispersion.Conclusion The thiolated hyaluronic acid nanoparticles may be used as the carrier for oral drug delivery system of insulin,and it provides a basis for studies on rats in vivo.福建省自然科学基金(2012J05159

    Functional groups of benthic macrofauna in the 14th Yong intertidal zone of Nansha,Guangzhou

    Get PDF
    大型底栖动物根据食性可分为浮游生物食者(planktophagous,Pl)、植食者(phytophagous,Ph)、肉食者(carnivorous,C)、杂食者(omnivorous,O)和碎屑食者(detritivorous,D)五个功能群。本文根据2007–2008年度和2013–2014年度在茳芏(Cyperus malaccensis)、海桑(Sonneratia caseolaris)2种生境调查获得的各4个季度的大型底栖动物数据,分析了广州南沙十四涌潮间带大型底栖动物功能群的生境差异、季节变化和年际变化。2007–2008年度采集到26种大型底栖动物,低于2013–2014年度的36种。无论是2007–2008年度还是2013–2014年度,茳芏、海桑生境的大型底栖动物均以植食者的栖息密度和生物量最高,碎屑食者的栖息密度和生物量最低。生境比较得出,茳芏生境大型底栖动物浮游生物食者(Pl)的丰富度指数(d)、均匀度指数(J)和多样性指数(H')均高于海桑生境。年度比较得出,在茳芏和海桑生境,2013–2014年度浮游生物食者的丰富度指数、均匀度指数和多样性指数均高于2007–2008年度,这是因为2013–2014年度采集到红树蚬(Gelonia coaxans)和彩虹明樱蛤(Morerlla iridescens)等,而2007–2008年度没有采集到。Benthic macrofauna were classified into 5 functional groups,i.e.planktophagous(Pl),phytophagous(Ph),carnivorous(C),omnivorous(O) and detritivorous(D).The biotope difference,seasonal and annual variations of functional group of benthic macrofauna in the intertidal zone of the 14 th Yong of Nansha,Guangzhou were analyzed in this study according to the four seasonal data of benthic macrofauna collected in two biotopes(Cyperus malaccensis and Sonneratia caseolaris) in 2007–2008 and 2013–2014.A total of 26 species were recorded in 2007–2008,which was lower than 36 species in 2013–2014.Both in 2007–2008 and 2013–2014,phytophagous group showed the highest value while detritivorous group shared the lowest one in density and biomass.Habitat comparison showed that the abundance index(d),evenness index(J) and diversity index(H') of planktophagous group in Cyperus malaccensis habitat were all higher than those in Sonneratia caseolaris habitat.Annual comparison showed that the abundance index,evenness index and diversity index of planktophagous group in 2013–2014 were all higher than those in 2007 –2008 both in Cyperus malaccensis and Sonneratia caseolaris habitats because the planktophagous such as Gelonia coaxans and Morerlla iridescens and so on were collected in 2013–2014 but they were not found in 2007–2008.国家自然科学基金(41176089和41376113

    Development of New Coatings for Solid Phase Microextraction

    Get PDF
    作为一种样品前处理方法的固相微萃取(SOlId PHASE MICrOEXTrACTIOn,SPME)技术,具有操作方便、快速、灵敏和无需大量有机溶剂的优点,因此在分离分析方面得到了广泛的应用。涂层是SPME技术的核心部分,其性能决定了SPME的性能和应用范围,因此发展新型涂层一直是SPME研究和应用工作的重点。近年来随着涂层材料制备技术的发展,出现了一些新型涂层。这些新型涂层的出现进一步拓宽了SPME技术的应用范围。本文综述了近三年来SPME涂层的研究进展,并着重介绍新型涂层的制备方法和性质。As a kind of sampling preparation method,solid phase microextraction (SPME) has many advantages such as simplicity,versatility,sensitivity and solvent free.It has gained widespread acceptance in separation and analysis.As the key factor of the SPME technique,coatings on SPME fiber determine the performance and application of SPME technique.Consequently,developing new coatings is the most important work for SPME.With the development of preparation methods of SPME coatings,many new coatings have appeared in recent years,and these new coatings expand the application fields of SPME technique.This review summaries the development of new SPME coatings in the past three years,and mainly focuses on the preparation methods and properties of new SPME coatings.福建省科技重点项目(No.2007Y0032)资

    Experimental effects study of total flavonoids of Ajuga on nuclear transcriptional factor of kappa B in mesangial proliferative glomerulonephritis rats

    Get PDF
    目的探讨筋骨草总黄酮(TfA)治疗系膜增生性肾小球肾炎(MSPgn)大鼠后核转录因子-κb(nf-κb)及下游转化生长因子-β1(Tgf-β1)的变化。方法采用改良慢性血清病MSPgn大鼠模型,于造模第5周末检测尿蛋白,将尿蛋白阳性者随机分为模型组、雷公藤多甙(TWP)组、不同剂量TfA组。于造模第6周开始给药,6周后,测定各组大鼠的24 H尿蛋白定量、血生化和肾组织病理变化,MAXVISIOnTM即用型快速免疫组化一步法检测大鼠肾组织中nf-κb P65的表达,双抗体夹心法检测血清中Tgf-β1的变化。结果 TfA可显著降低尿蛋白,明显减小系膜区面积占毛细血管丛面积的百分比(P0.05)。模型对照组大鼠肾组织nf-κb P65、血清Tgf-β1的表达明显高于正常对照组[nf-κb P65:28.93±4.45 VS.4.51±0.96,P0.05).The renal tissue NF-κB(Integral optical density, IOD) and serum TGF-β1(pg/ml) in model control was significantly higher than that in normal control group, NF-κB p65 28.93±4.45 vs.4.51±0.96, P<0.01; TGF-β1:(247.63±51.55)pg/ml vs.(127.52±27.84)pg/ml, P<0.01; With the intervention trerapy of high-dosage TFA, middle-dosage TFA and TWP, the expression of NF-κB in renal tissue and TGF-β1 in serum was significantly decreased compared with model control group, NF-κB p65: 10.35±2.81, 15.21±4.71,11.70±3.97, P<0.01; TGF-β1:(181.96±52.93)pg/ml,(204.33±38.30)pg/ml,(188.07±42.92)pg/ml, P<0.05.Conclusion Reducing the expression of NF-κB and successive TGF-β1 may be one of the mechanisms of total flavonoids of Ajuga treatment on MsPGN rats.福建省卫生厅中医药科研重点课题(wzzsb0906); 陈可冀中西医结合发展基金·福建省中西医结合老年性疾病重点实验室开放课题资助项目(CKJ2008088); 福建中医药大学校管课题(X2009069

    试论上市公司高管薪酬的粘性——基于我国金融业上市公司的研究视角

    Get PDF
    本文以中国股票市场中金融业上市公司为样本,对高层管理人员薪酬粘性问题展开研究。研究发现,高管薪酬存在粘性,即在公司绩效上升时高管薪酬增加幅度显著高于公司绩效下降时的减少幅度。进一步研究还发现,公司规模、股权安排、负债比例等一系列特征对高管薪酬粘性具有显著的影响关系。本文研究不仅揭示我国上市公司高管薪酬变动特征,同时也为学术界进一步研究高管薪酬粘性问题提供理论基础与数据支持

    Development of aquantitative ELISA detection method for Varicella Zoster Virus(VZV) antigen

    Get PDF
    目的:建立水痘-带状疱疹病毒(VzV)抗原的双抗体夹心ElISA定量检测方法,用于质控VzV灭活疫苗研发和生产中抗原含量。方法:以VzV中和单抗5f6C8为包被抗体、8H5d1为酶标抗体,构建定量检测VzV抗原的双抗体夹心ElISA方法,并对本方法的特异性、灵敏度、准确性、线性和稳定性等性能进行分析。结果:建立的双抗体夹心定量检测VzV抗原的ElISA方法,线性范围为0.4μg~13μg/Ml,相关系数为r2=0.994,定量限度为0.4μg/Ml;变异系数CV80%。与VzV以外的相关病毒样本没有交叉反应。结论:构建的VzV抗原ElISA定量检测方法的各项性能符合定量检测需要,可用于VzV灭活疫苗的研发和生产过程的抗原含量检测。Objective:To develop a quantitative enzyme linked immunosorbent assay(Q-ELISA) to determine the concentration of Varicella Zoster Virus(VZV) antigen.This method was used to determine VZV antigen content at each stage of VZV inactived vaccine developing and manufacturing process.Methods: A double antibody sandwich Q-ELISA was developed to determine concentration of VZV antigen,which was based on the the high-affinity neutralizing monoclonal antibodies 5F6C8 as capture antibodies,and 8H5D1 as HRP-labeled antibody.The performance of reagent were evaluated.Results: The Q-ELISA for VZV antigen content was successfully developed.The reagent had good performance.The quantitation scope was 0.4 μg~13 μg/ml,The coefficient correlation was 0.994,the limit of detection was 0.4 μg /ml,the recovery was between 87.5% and 111.6%.The stability was up to 80% after reagent was heated for 6 days at 37℃.The variation coefficient was lower than 15%,and the reagent was no reaction with other sample except VZV antigen.Conclusion: The Q-ELISA for VZV antigen was developed with good specificity,accuracy and stability.The method can be used to determine VZV antigen content during development and production of VZV inactived vaccine

    Development of New Coatings for Solid Phase Microextraction

    Get PDF
    As a kind of sampling preparation method, solid phase microextraction (SPME) has many advantages such as simplicity, versatility, sensitivity and solvent free. It has gained widespread acceptance in separation and analysis. As the key factor of the SPME technique, coatings on SPME fiber determine the performance and application of SPME technique. Consequently, developing new coatings is the most important work for SPME. With the development of preparation methods of SPME coatings, many new coatings have appeared in recent years, and these new coatings expand the application fields of SPME technique. This review summaries the development of new SPME coatings in the past three years, and mainly focuses on the preparation methods and properties of new SPME coatings
    corecore