The Relationship Between Self-concept,Achievement Goal and Mental Healthof Vocational School Students

目的:探察职高生自我概念、成就目标及与心理健康之间的相互关系。方法:采用自我概念问卷、成就目标问卷和SCL-90对450名职高生进行问卷调查。结果:人口学变量中除年级因素外(P0.05); 越倾向成绩目标者,心理问题越多(P<0.05); 越倾向于学习目标者,心理问题越少(P<0.001),但此作用受到自我概念的中介,拥有更高自我概念者,心理问题越少(P<0.001)。结论:在关注职高生的心理健康状况时,可以从自我概念和成就目标两个方面入手进行干预

Distribution Characteristics of Polycyclic Aromatic Hydrocarbons in Seawater from the South Yellow Sea

2007年9月进行了2007南黄海海洋环境调查,并采集各个调查站位的表层、中层、底层海水及表层沉积物。利用液-液萃取法对采集到的样品进行前处理,并用气相色谱-质谱法检测海水中的多环芳烃。结果显示,监测站位中表层海水中总多环芳烃的含量范围是15.76--233.39ng/l,南黄海中部海水中多环芳烃的组成以2环的萘为优势组分;各种多环芳烃的含量与国际生物学组织或国家制定的评价水生生物暴露于水体的安全食用标准相比虽未超标,但个别组分如荧蒽的含量已达到生态毒理评价标准。Marine surface sediments and sea water samples from the surface, middle and bottom layers were collected from the South Yellow Sea of China.The samples were pretreated by liquid-liquid extraction and the 16 polycyclic aromatic hydrocarbons (PAHs) in the samples were determined by gas chromatography-mass spectrometry (GC-MS).The results show that the range of total PAHs is 15.76～233.39 ng/L in surface water and PAHs in the water samples from central South Yellow Sea are dominated by naphthalene (2 rings).Content of PAHs compounds don′t exceed the safety guidelines proposed by International Biology Organization or governments, but the individual compound, such as fluoranthene content has reached eco-toxicological evaluation criteria.国家海洋局节能减排专项资助;中国海监技术支撑项目资助;海洋公益性项目资助(200705011

Comparison of Recoveries of PAHs Obtained by Ultrasound-assisted Extraction from Wet and Freeze-dried Marine Sediment

以美国环保局(EPA)优先控制的16种多环芳烃(polycyclic aromatic hydrocarbons,PAHs)为研究对象,建立了湿法超声波辅助萃取技术提取沉积物中痕量PAHs的可靠方法,对萃取剂、萃取功率、萃取次数和萃取时间进行了优化。并与传统干法超声辅助萃取进行了比较,湿法超声波辅助萃取的PAHs回收率为57%～125%,而干法超声波辅助萃取PAHs的回收率为48%～113%,对相对分子质量小的PAHs如萘～芴的回收率,湿法明显高于干法。该文建立的湿法超声辅助萃取适用于沉积物和泥土中痕量PAHs的快速测定。An ultrasound-assisted extraction method for the extraction of 16 trace PAHs(USEPA priority pollutant) from wet(i.e.untreated) marine sediment was developed.The effects of solvent type,power of ultrasound,and extraction time were studied and optimized.The developed method was compared with the traditional ultrasound-assisted extraction for freeze-dried sediment.The results showed that recoveries of sixteen PAHs extracted from the wet marine sediment ranged from 57% to 125%,whereas those extracted from the freeze-dried marine sediment ranged from 48% to 113%.The results also indicated that the recoveries of PAHs with smaller relative molecular mass(e.g.naphthalene and fluorine) extracted from the wet sediment were higher than those from the freeze-dried sediment.Thus the developed method was appropriate for rapid determination of trace PAHs in marine sediment and soil.海洋公益性行业科研专项(200705011);; 中国海监技术支撑体系项目;; 2008年海洋环境保护及节能减排专

Concentration and distribution of polycyclic aromatic hydrocarbons in surface sediments collected in the Southern Yellow Sea

采用气相色谱与质谱联用(gC/MS)技术,在一个航次内对南黄海表层沉积物中16种优先监控的PAHS的污染状况进行了调查,采用菲/蒽、荧蒽/芘、荧蒽/(荧蒽+芘)、吲哚芘/(吲哚芘+苯并(g,H,I)苝)等特定比值对PAHS来源进行了分析.结果表明,南黄海表层沉积物中检出PAHS的总含量为90.4~732.65ng·g-1,各站点均以4~6环为主;与其它站位相比,倾废区的H01站位受到PAHS污染较为明显,无论是16种PAHS总量还是高分子量组分最高值都出现在该站点,虽然该海区沉积物中PAHS的含量没有超出生物影响低值,但苯并(b)荧蒽、吲哚芘和苯并(g,H,I)芘等一些没有最低安全标准的PAHS也有不同程度的检出,对海洋生物具有潜在的毒副作用.PAHS可能来源于原油、生物和煤燃烧造成的污染.The concentrations of sixteen representative Polycyclic Aromatic Hydrocarbons(PAHs) in surface sediment samples collected from the Southern Yellow Sea were determined by GC-MS.The distribution and potential sources of PAH contamination in the region were investigated.The types of PAHs found in the surface sediments were mainly 4～6 ring PAHs,and they are unevenly distributed among the different sampling sites covering an area of 139 km2.The area is known for continuous waste dumping activities in recent years,and indeed sites adjacent to such activities were found to have high levels of PAHs.Some high molecular weight PAH compounds such as benzo$$b$$fluoranthene,dibenzo$$a,h$$anthracene and benzo$$g,h,i$$perylene were detected in some samples.The health implication of these contaminants needs careful assessment since toxicity guidelines are not available for these species.The potential sources of PAHs are discussed using various source-specific PAH indexes such as Phenathrene/Anthracene、Fluoranthene/Pyrene、Fluoranthene/(Fluoranthene+Pyrene) and Indeno [1,2,3-cd] pyrene/(Indeno[1,2,3-cd] pyrene+Benzo [g,h,i] perylene).The composition of the observed PAHs reflects that they originate from both petroleum utilization and incomplete combustion.海洋公益性行业科研专项(No.200705011);中国海监技术支撑体系项目;2008年海洋环境保护及节能减排专项---

高致病性禽流感病毒血凝素蛋白广谱中和表位模拟肽的筛选与鉴定

以H5N1型禽流感病毒HA蛋白广谱中和单抗8H5为基础,利用噬菌体展示肽库技术及类病毒颗粒融合表达技术研究HA模拟表位。ELISA检测结果显示:筛选获得模拟HA表位的模拟肽123,进行类病毒颗粒融合蛋白表达后,仍具有与8H5单抗特异结合的能力。免疫荧光检测结果说明,类病毒颗粒免疫小鼠后产生了能与HA交叉反应的抗体。禽流感病毒HA模拟表位的研究与性质的分析及类病毒颗粒融合蛋白的表达与活性分析、免疫原性分析,都为研制禽流感通用表位疫苗奠定了基础

养正消积胶囊辅助GP方案治疗晚期非小细胞肺癌临床研究

目的观察养正消积胶囊辅助GP方案治疗晚期非小细胞肺癌(NSCLC)的临床疗效。方法采用随机数字表法将89例晚期NSCLC患者分为对照组44例及观察组45例。2组均采用GP方案;观察组并予养正消积胶囊,每次4粒,每日3次,口服。2组均21d为1个周期,连续治疗2个周期,随访1年。观察2组治疗前后Ki67、Bax、Bcl-2蛋白表达及肿瘤标志物[血管内皮生长因子(VEGF)、骨桥蛋白(OPN)、癌胚抗原(CEA)、糖类抗原199(CA199)]、中医症状评分、生活质量评分,比较2组客观缓解率(ORR)、疾病控制率(DCR)、无进展生存时间(PFS),监测不良反应。结果观察组ORR、DCR明显优于对照组(P<0.05)。与本组治疗前比较,观察组治疗后、随访1年VEGF、OPN、CEA、CA199水平明显降低(P<0.05);对照组治疗后上述指标明显降低(P<0.05),随访1年CEA水平明显降低(P<0.05)。与本组治疗前比较,2组治疗后Ki67、Bcl-2蛋白表达明显降低,Bax蛋白表达明显升高(P<0.05);2组治疗后比较,观察组Ki67、Bcl-2蛋白表达低于对照组(P<0.05),Bax蛋白表达高于对照组(P<0.05)。与本组治疗前比较,2组治疗后中医症状评分(神疲乏力、胃纳少馨、腰膝无力、夜尿频多、头晕目眩)、生活质量评分(躯体功能、认知功能、社会功能、情绪功能)明显改善(P<0.05);2组治疗后比较,观察组上述评分改善明显优于对照组(P<0.05)。观察组PFS明显长于对照组(P<0.05),不良反应明显低于对照组(P<0.05)。结论养正消积胶囊辅助GP方案治疗晚期NSCLC可有效降低患者肿瘤标志物水平,改善生存质量,减少吉西他滨和顺铂的不良反应,提高疗效。福建省卫生厅中医药科研专项课题(wst201210

The Relationship Between Self-concept, Achievement Goal and Mental Health of Vocational School Students

目的：探察职高生自我概念、成就目标及与心理健康之间的相互关系。方法：采用自我概念问卷、成就目标问卷和SCL-90对450名职高生进行问卷调查。结果：人口学变量中除年级因素外（P〈0.05）,是否独生子女、性别和年龄等因素对心理健康的预测作用不显著（P〉0.05）;越倾向成绩目标者,心理问题越多（P〈0.05）;越倾向于学习目标者,心理问题越少（P〈0.001）,但此作用受到自我概念的中介,拥有更高自我概念者,心理问题越少（P〈0.001）。结论：在关注职高生的心理健康状况时,可以从自我概念和成就目标两个方面入手进行干预

基于双时隙多幅值的映射复用技术的研究

为了有效提高光通信系统的频带利用率,提出了一种新型复用技术——映射复用（MM）,即采用双时隙多幅值信号对多路复用信号的单值映射来实现对多路信号的复用。分析了MM技术的复用和解复用原理,以4路用户信号复用为例,利用Matlab软件设计了MM复用器和解复用器。采用Optisystem和Matlab联合仿真,设计了一种基于MM技术的4路用户信号复用的光纤传输系统。仿真实验得到的眼图清晰,验证了方法的可行性;与同速率的非归零和归零信号相比,MM信号的谱宽分别是它们的一半和1/3。MM技术可有效地提高系统的频带利用率,增加色散容忍度,在光纤通信系统中具有广泛的应用前景

431名北京职高生心理健康状况的调查

本研究采用症状自评量表（SCL-90）考察北京职高生的心理健康，为职高校开展心理健康教育提供参考

431名北京职高生心理健康状况的调查

本研究采用症状自评量表（SCL-90）考察北京职高生的心理健康，为职高校开展心理健康教育提供参考