90 research outputs found

    A Study about the Business Model of WeBank ——Based on the Model and Experience of Internet Finance in America

    Get PDF
    互联网金融出现于20世纪90年代互联网热潮下的美国,当时由于互联网技术的迅速普及和发展,使其快速向传统商业和金融业领域扩散,并随之出现了多种互联网金融模式和知名公司,包括美国第一家网络经纪商E-trade、第一家网络银行美国安全第一网络银行(SecurityFirstNetworkBank)以及与支付宝类似的互联网支付公司Paypal等,后续随着逐步的摸索发展,此类公司兴衰更迭,使得美国互联网金融模式逐步完善,并成为互联网金融发展的先驱,带给我们深刻的借鉴和启迪。 随着我国国内政策以及相关监管部门对互联网金融逐步放开,近年来互联网金融这一话题在国内越来越火热并受到普遍关注,尤其是腾讯微众银行...The Internet Financial first appeared at 20 century in America owing to the development of the Internet. With the rapidly development and application of the internet, it is widely used in the traditional business as well as the financial area. Some famous companies like the E-trade, Security First Network Bank as well as the Paypal established during that time. As time goes on, some of the compani...学位:工商管理硕士院系专业:管理学院_工商管理硕士(高级管理人员工商管理硕士)学号:X200815605

    Research on practice of government's purchasing social work services from Public Administration Perspective —— with XM city as an example

    Get PDF
    2006年,我国真正开启了社会工作职业化进程。经过近十年的努力,社会工作发展的体制机制更加健全、人才队伍越来越壮大。在这个过程中,全国各地积极推进政府购买社会工作服务,实践经验逐步丰富,政策制度不断完善,购买资金量不断上升。XM市自2007年以来,也不断加大力度推进社会工作专业人才队伍建设,并于2010年开始了政府购买社会工作服务的探索,至今取得不少成就。近两三年,国内学者对政府购买社会工作服务进行了许多研究,但对XM市这方面工作的研究较少,而XM市的政府购买社会工作服务实践在国内二三线城市是有一定代表性的。鉴于此,笔者期望,以公共管理为视角,以新公共管理理论的企业家政府模式为指导,立足XM市...In 2006, the process of China’s social work’s professionalism has been truly launched. After nearly 10 years of efforts, with the development of the social work system and mechanism, the growth of professional procession, the whole country actively promote the government’s purchasing social work services, which leads to the increasing of practice experience, the perfection of the policy system and...学位:社会工作硕士院系专业:公共事务学院_社会工作硕士学号:1402014115052

    Research on the Brand Management of Newspaper’s Network:A Case Study of Xiamen

    Get PDF
    关于报纸网站建设或者报网互动的理论与实践研究,自互联网出现后就是热点话题。中国报纸的网站处于品牌建设起步阶段,虽然报人已经有了塑造频道品牌的意识,但是在运营过程当中,由于对于品牌管理的要素缺乏系统的认识,无法实现全面系统的管理,使得塑造的品牌形象模糊。因此,很有必要就报纸网站的品牌化管理加以系统研究。《法制日报》是中央政法委机关报。为进一步扩大《法制日报》在全国的影响和发行量,《法制日报》在全国各地设立了工作站,2009年法制日报网开通了厦门频道,作为厦门市政法系统面向全国的一个重要互联网宣传窗口。法制日报厦门频道面临如何迅速提升网站知名度,提升网站品牌形象,扩大影响力的任务。本文以法制日报厦...Since the advent of internet, researches on how to construct newspaper on the web or how to realize the interaction between newspaper and internet are still a hot topic at home and abroad in spite of theory and practice.It is essential to make efforts to study brand mamagment of newspaper on the web systematicaly because it is a beginning for China to construct newspaper on the web which must put ...学位:工商管理硕士院系专业:管理学院工商管理教育中心(MBA中心)_工商管理硕士(MBA)学号:1552005130153

    中美公司环境信息披露比较

    Get PDF
    通过对中美上市公司环境信息披露的比较,可借鉴美国环境信息披露制度及其成功的实践经验,有效提高中国上市公司环境信息披露水平在法律法规、社会舆论和经营业绩对于产生环境污染的企业特别是重污染企业的影响下,企业的社会责任意识正在逐步增强。而这种环保意识的增强体现在企业战略战术、日常经营以及对环境污染的治理方案中。潜在的信息使用者需要通过企

    “茶禅一味”——论中国禅宗思想对日本茶道的影响

    Get PDF
    禅宗思想和茶道文化均源自于中国,当两者传入日本之后,对日本文化产生了重要影响。日本茶道是日本文化的一部分,无论是其建立还是发展,都在某种程度上体现了在禅宗思想上的继承。而日本茶道中倡导的"和敬清寂"又将禅宗思想发扬光大,使之升华为日本民族的生命哲学

    Fiber Bragg Grating AC Current Measurement Based on Twin-Core Fiber Filter

    Get PDF
    中文摘要:利用光纤光栅( Fiber Bragg grating ,简称 FBG) 、 超磁致伸缩材料( Giant magnetost riction material ,简称 GMM)和基于双芯光纤滤波器的解调系统实现了交流电流的测量。在介绍超磁致伸缩材料的磁致伸缩效应、 光纤光栅检测电流原理以及双芯光纤滤波器解调原理的基础上 ,借助超磁致伸缩材料和光纤光栅等构建了电流测量单元。利用设计的电流测量单元 ,在施加 0~4. 5 A (50 Hz)范围的交流激励电流时 ,经基于双芯光纤滤波器的解调系统解调 ,验证了采用该方案检测电流的可行性。 英文摘要:基金项目:国家自然科学基金项目资助(60472025

    Research Progress on Hybrid Solar-Geothermal Power Generation

    Get PDF
    Developing and using combined new energy sources is an important direction of development for new energy in future. The first Hybrid Solar-Geothermal Power station has been built, and related research on this field has been carried out vigorously. Accord

    芳樟树叶乙醇提取物的抗癌作用

    Get PDF
    探讨了芳樟树叶乙醇提取物各部分的抗癌作用。采用系统溶剂法从芳樟树叶得到一系列提取物,运用MTT和集落形成实验法考察各提取物对体外培养的人肺癌95-D细胞、人口腔表皮样癌KB细胞和肝癌HepG2细胞增殖的影响。结果发现石油醚部分A1、氯仿部分A2和乙酸乙酯部分A3对3种肿瘤细胞的增殖和集落形成均有不同程度的抑制作用,且给药量与细胞抑制和集落形成明显的正相关关系。因此,芳樟树叶乙醇提取物在体外有明显的抗肿瘤作用,且抗癌有效组分很可能在它的石油醚部分、氯仿部分以及乙酸乙酯部分

    Elemene reversed the multidurg resistance of A549 /DDP lung cancer cells via mitochondrial apoptosis pathway

    Get PDF
    目的:探讨榄香烯乳(ElEMEnE,ElE)逆转人肺腺癌耐顺铂(CISPlATIn,ddP)细胞A549/ddP的耐药性及作用机制。方法:采用MTT法检测榄香烯乳单用的细胞毒作用及与ddP合用时耐药逆转作用。荧光探针JC-1结合激光共聚焦显微镜检测线粒体膜电位的变化。dCfH-dA荧光探针结合流式细胞仪检测细胞内活性氧(rEACTIVE OXygEn SPECIES,rOS)水平。用谷胱甘肽试剂盒结合分光光度法检测计算gSH/(gSSg+gSH)比值。蛋白质印迹法检测胞质中CyTO C、PrO-CASPASE-3、CASPASE-3和bCl-2家族蛋白表达情况。结果:不同浓度榄香烯乳抑制A549/ddP细胞株生长,呈时间-剂量依赖性效应,联合顺铂能提高A549/ddP细胞株对顺铂的敏感性而逆转耐药。不同浓度榄香烯乳联合顺铂使A549/ddP细胞株线粒体膜电位下降,rOS浓度增加,gSH/(gSSg+gSH)比值降低,上调胞质中CyTO C、CASPASE-3、bAd蛋白表达,下调PrO-CASPASE-3、bCl-2蛋白表达。结论:榄香烯乳逆转A549/ddP细胞株耐药性可能与其损伤线粒体膜,活化胞内氧化还原体系,诱导线粒体凋亡路径有关。Objective: To explore the mechanism that elemene( ELE) reversed the multidurg resistance( MDR)of A549 /DDP lung adenocarcinoma cell.Methods: MTT assay was used to determine the growth inhibition of human lung adenocarcinoma A549 /DDP cells in vitro.Mitochondrial membrane potential( MMP) was monitored by JC- 1fluorescence probe with laser confocal scanning microscopy,the intercellular reactive oxygen species( ROS) level was measured by 2',7'- dichlorfluorescein- diacetate( DCFH- DA) staining and flow cytometry and the ratio of GSH /( GSSG +GSH) was calculated according to detection results of GSH kit.The expression of Cytochrome C,Caspase-3 and the Bcl- 2 family proteins and in the case of cyclosporine A and DEVD- CHO,the expression of Caspase- 3expression were measured by Western blot.Results: MTT results showed that different concentrations ELE could inhibit the proliferation of A549 /DDP cells in a time- and dose- dependent manner.Intriguingly,ELE plus cisplatin enhanced the sensitivity of A549 /DDP cells to cisplatin and reversed A549 /DDP cells dury resistance.Different concentrations ELE decreased mitochondrial membrane potential,increased intracellular ROS concentration and decreased GSH /( GSSG + GSH) ratio of A549 /DDP cells in a time- and dose- dependent manner.Furthermore,the combination with both ELE and cisplatin also enhanced the protein expression of Cytoplasmic C,Caspase- 3 and Bad,and reduced the protein levels of Bcl- 2 and Pro- caspase- 3 in the cisplatin- resistant A549 /DDP cancer cells.Conclusion: ELE reversed the MDR of A549 /DDP cell line may demage mitochondrial membrane,active intracellular redox system and induce the mitochondrial apopotosis pathway.福建省自然科学基金面上项目(编号:2010D014

    The efect of elemene reversing the multidurg resistance of A549/DDP lung cancer cells

    Get PDF
    目的 :探讨榄香烯乳(ElEMEnE)逆转人肺腺癌耐顺铂(CISPlATIn,ddP)细胞A549/ddP的耐药性及可能的作用机制。方法 :采用MTT法检测榄香烯乳单药作用时的细胞毒作用及与ddP联合作用对A549/ddP细胞耐药的逆转作用;HOECHST 33342法进行细胞核染色,荧光显微镜下观察细胞形态的改变;fCM检测细胞凋亡率;蛋白质印迹法检测细胞质中细胞色素C(CyTOCHrOME C,CyT C)、PrO-CASPASE-3、CASPASE-3和抗凋亡因子b细胞淋巴瘤-2(b CEll lyMPHOMA-2,bCl-2)家族蛋白表达的情况。结果 :不同浓度榄香烯乳对A549/ddP细胞均有一定的抑制作用,呈时间-剂量依赖性效应,联合ddP能提高耐药细胞株A549/ddP对ddP的敏感性而逆转其耐药性。HOECHST 33342法和fCM法检测结果显示,榄香烯乳联合ddP能更大程度上诱导A549/ddP细胞的凋亡,提高耐药细胞的凋亡率,同时还上调A549/ddP细胞质中CyT C、CASPASE-3和bAd蛋白的表达,而下调PrO-CASPASE-3和bCl-2蛋白的表达。结论 :榄香烯乳能逆转A549/ddP细胞耐药性可能与其损伤线粒体膜,使线粒体释放CyT C到细胞质、同时活化CASPASE-3、上调促凋亡蛋白bAd和下调抗凋亡蛋白bCl-2表达以启动凋亡路径有关。Objective: To investigate the effect of elemene on the drug resistance of cisplatin(DDP)- resistant human lung adenocarcinoma A549/DDP cells, and its possible mechanism.Methods: The growth inhibition of A549/DDP cells treated with elemene alone or combined with different concentrations of DDP was detected by MTT assay.The morphological changes of apoptosis of A549/DDP cells treated with different concentrations of elemene(20 and 40 μg/mL) for 24 h were observed by Hoechst 33342 staing under fluorescence a microscope.The apoptosis rate of A549/DDP cells treated with different concentrations of elemene(20 and 40 μg/mL) after 24 h were detected by FCM(flow cytometry).The expressions of cytochrome C, pro-caspase-3, caspase-3 and the Bcl-2 family proteins were measured by Western blotting analysis.Results: MTT result showed that different concentrations elemene could inhibit the proliferation of A549/DDP cells in a time- and dose- dependent manner.Intriguingly, elemene plus DDP enhanced the sensitivity of A549/ DDP cells to DDP and reversed the resistance of A549/DDP cells.Elemene was also a strong inducer of apoptosis in this model system, and a synergistic effect on induction of cell death was observed when the tumor cells were treated with both agents.The result showed that elemene could enhance A549/DDP cell apoptosis.Furthermore, the combination of elemene and DDP also enhanced the protein expressions of cytochrome C, caspase-3 and Bad, and reduced the protein levels of Bcl-2 and pro-caspase-3 in the A549/DDP cells.Conclusion: The reversal of the multi-drug resistance of A549/DDP cell line by elemene may result from its effect on induction of apoptosis.Elemene treatment can impaire mitochondrial membrane, release cytochrome C into cytoplasm, activate caspase-3,up-regulate pro-apoptotic protein Bad and down-regulate anti-apoptotic protein Bcl-2, and finally caused apoptosis.福建省自然科学基金面上项目(编号:2010D014
    corecore