Comprehensive research on character of collapse and fracture of thick and large overburden rock in cave mining

大红山铁矿采用无底柱分段崩落法开采,形成了规模巨大的采动区域,上覆岩层厚度达627~750 m。为了掌握上覆岩层中崩落、开裂与高应力集中区的范围及发展趋势,防止突发性的大规模动力地压灾害的发生,矿山采取多通道微震监测技术、巷道观测和钻孔探测相结合的方法,对上覆岩层进行全面监测和研究。通过多通道微震监测技术对上覆岩体中高应力集中区破裂源进行高精度定位,确定高应力集中区及其变化过程,并据此推断开裂带的外边界;同时基于双力偶点源理论,分析得到震源破裂类型为以体积增加的张拉型为主、压剪切破坏与混合破坏为辅。在专门的巷道中,通过人工直接观察,确定崩落边界、开裂带的内、外边界;地表深钻孔探测作为辅助性手段,用来确定(验证)开裂带的外边界。将这3种技术手段结合起来对2011~2013年间上覆岩层不同时期的崩落带、开裂带与高应力集中区进行综合监测,得到不同时期高应力区、开裂带和崩落带的发展过程。研究表明,上覆岩层中崩落与开裂发展过程是一个缓慢渐进的过程,不会产生大规模的突变型崩塌冲击地压灾害。本文研究成果对矿山的安全生产具有重要的指导作用。A bulky mining-out area was formed at Dahongshan iron mine with sublevel caving method. The thickness of overburden is 627 to 750 meter. In order to understand the development of collapse area,fractured zone and high stress concentration zone in overburden so as to prevent the sudden large-scale and dynamic ground pressure disasters,micro-seismic monitoring,tunnel observation and borehole detection methods were used to carry out the comprehensive monitoring and research. Base on the precise location of fracture source with multi-channel micro-seismic monitoring technology,high-stress concentration zone and its developing trend were determined,and then the outer boundary was deduced. At same time,the analysis on fracture types of fracture source with double couples model showed that the tension fracture with volume-increasing accounted for majority of all sources,while the shear failure and mixed failure accounted for minority. The boundary of collapse area,external and internal boundaries of fractured area were determined directly through the artificial observation in special tunnels. The borehole detection as the auxiliary method was used to determine and validate the external boundary of fractured zone. A comprehensive monitoring and analysis were carried out to obtain the caving zone,cracking zone and high stress concentration area in overburden in different periods from 2011 to 2013. The development of high stress zone,cracking zone and caving zone in different periods were also obtained. The studies showed that the caving and cracking processes in overburden were slow and gradual. The sudden and dynamic large-scale collapse disaster would not occur. The conclusion of this paper played an important role in guiding the safe production of the mine.国家科技支撑计划项目(2013BAB02B06);; 国家科技部科研院所技术开发研究专项资金项目(2013EG21024)~

固氮酶底物络合活化模式的量子化学计算

用改进的ＥＨＭＯ方法对分子氮和乙炔作为固氮酶底物时的络合活化模式进行了总能量及电荷分布的量化近似计算。结果表明固氮酶底物活性中心（ＦｅＭｏ－ｃｏ）对于分子氮和其它底物在络合活化时是区别对待的

Research on T Lymphocyte Subsets and NK Cells Activity in Peripheral Blood of Hypopharyngeal Squamous Cell Carcinoma

目的:分析下咽鳞状细胞癌患者外周血T淋巴细胞亚群和NK细胞活性情况,旨在为相关研究工作提供参考资料。方法:择取2011年6月-2016年5月本院收治的95例下咽鳞状细胞癌病患为病例组,另取此期间内来本院接受健康检查的72例志愿者为正常组。使用流式细胞仪对病患开展相关检查,分析病例组与正常组的淋巴细胞亚群、NK活性情况以及不同临床分期的下咽癌病患外周血T淋巴细胞亚群以及NK细胞活性之间的关系。结果:与正常组相比,病例组的NK细胞、总B淋巴细胞、总T淋巴细胞、辅助/抑制T细胞、辅助T细胞偏低(P0.05)。Ⅰ~Ⅱ期病患辅助T淋巴细胞比Ⅲ~Ⅳ期者略高(P>0.05)。Ⅰ~Ⅱ期病患抑制T淋巴细胞值比Ⅲ~Ⅳ期者低(P0.05)。Ⅰ~Ⅱ期病患外周血NK细胞数比Ⅲ~Ⅳ期者略高(P>0.05)。结论:下咽鳞状细胞癌病患的免疫功能异常,且随着疾病的进展,细胞免疫和体液免疫均有所降低,证实免疫功能紊乱在疾病进展中发挥了一定作用。经流式细胞设备对外周静脉血淋巴细胞亚群以及NK细胞活性情况检测,可实现动态化检测癌症病患某阶段细胞免疫功能变化详情,此法方便简单,在指导治疗方案制定以及监测疾病预后方面,均体现出了一定效果,值得进一步推广

Sarcomatoid Carcinoma of Hypopharynx： A Report of 5 Cases

目的探讨下咽肉瘤样癌的临床及病理学特点,为下咽肉瘤样癌的诊治提供参考依据,提高对肉瘤样癌的诊断、治疗及其预后的认识。方法分析2010年1月—2014年9月我院治疗的5例下咽肉瘤样癌患者的临床资料,包括诊疗过程、病理特征等。结果 5例患者均经过不同的手术方式,其中咽后壁扩大切除1例,梨状窝扩大切除2例,全后、全下咽、全食管切除2例;肉瘤样癌肉瘤样成分与癌成分共存,且之间有一定的移行,CK、vimentin均表达阳性,P63阳性4例。5例患者均定期随访。结论下咽肉瘤样癌有其特殊的生物学行为及病理学特点,是一种不同于其他类型的恶性肿瘤,具有自身病理特征,预后情况各不相同,外科手术仍是首选治疗方法,术后辅助放化疗。Objective To explore the biological behavior and clinical features of the sarcomatoid carcinoma（SC） of hypopharynx for improving the diagnosis,treatment and judgment of prognosis of the tumor.Methods Clinical data,including treatment process and pathology features of the 5 cases of SC underwent operation in our department from January 2010 to September 2014 was analyzed retrospectively.Results All the five patients underwent different surgical procedures and all survived,one case received pharyngeal extended resection,tow cases received pyriform extended resection and tow cases received total throat、swallow、esophagectomy resection.The biological of sarcomatoid carcinoma of head and neck performed components and cancer components coexisted,and has a certain shift between them,CK and vimentin expressed was positive in all cases,P63 was positive in 4 cases.All patients were followed up regularly.Conclusion Sarcomatoid carcinoma of hypopharynx has its special biological behavior and pathology characteristics,it is different from other types of malignant tumors,and has its own pathological features,surgeryis is still the preferred method,postoperative assistance chemotherapy is needed

柿竹园多通道微震监测系统的建立及其应用

在柿竹园多金属矿床,由于大量集中采空区群的存在,采矿生产过程中地压现象显现严重,安全生产受到严重威胁。为此,公司与长沙矿山研究院合作,在优化采矿工艺的基础上,先后建立了多种常规地压监测系统,并从加拿大ESG公司引进地压监测设备,于2008年11月建立了国内矿山最大通道的全数字型微震监测系统。详细介绍了微震监测系统的建立、优化及其现场应用情况,论述了多通道微震监测技术在矿山地压灾害防治方面所展示的优势和效果

Observation on Aggregation and Resting on Spider Web Behavior of Crane Fly Limonia(Euglochina) sp.from Nanjing Subtropical Rainforest of China

通讯作者: [email protected][中文文摘]在南靖和溪亚热带雨林中分布有数种大蚊,美刺亮大蚊(Lim onia(Euglochina)sp.)是雨林中唯一观察到在圆蛛科蜘蛛网上栖息的大蚊.因此我们对美刺亮大蚊和圆蛛科蜘蛛在蜘蛛网上的同现行为进行了观察研究.借助扫描电镜技术,在比较了其他大蚊、蜘蛛等节肢动物前跗节超微结构的基础上,对美刺亮大蚊栖息于蜘蛛网行为学的形态学机制进行了初步解析.文中也对美刺亮大蚊的聚集行为与雨林温湿度的关系进行了记录.[英文文摘]There are several species of crane flies in Nanjing subtropical rainforest,whereas,the Limonia(Euglochina) sp.is the only one we observed resting on the spider web(primary thread favor).So,observation on co-occurrence behavior of Limonia(Euglochina) sp.with the Araneidae spiders in the same orb-web was conducted.Ultrastructure of the pretarsus of several species of crane flies and one spider species of Araneidae were scanned by SEM technology,in addition,the mechanism of hanging on the orb-web thread by Limonia (Euglochina )sp.was discu ssed in this paper by comparing the tarsal externalmorpho logy of Limonia (Euglochina )sp.with the others. We also recorded the aggregation regulation of Limonia (Euglochina )sp.in the working field in the rainforest.国家基础科学人才培养基金(J0630649);厦门大学第一届大学生创新实验项目资

知识产权被许可人诉权研究

在我国知识产权法律制度中,知识产权被许可人的诉权地位存在明显的依附性,造成了知识产权被许可人的维权困境。传统的知识产权理论体系中对知识产权许可产生的实施权的属性有多种解读模式,无论是纯粹的债权理论、债权的物权化理论亦或诉权约定理论均并不能从根本上解决被许可人的诉权问题,其根本原因在于对知识产权许可权的属性的定位偏离。在"二元知识产权"理论框架下,知识产权实施权被合理地赋予"用益权"属性,无论是独占许可、排他许可还是普通许可的被许可人都成为用益权人,均能获得相对独立的诉权,从而实现从实体法到诉讼法的无缝对接,保障知识产权被许可人的合法权益。广西民族大学中国-东盟研究中心(广西科学实验中心)开放课题项目:中国-东盟技术转移中的知识产权保护法律问题研究(KT201301

THE NEW ALGORITHM 0F GROUP SyMMETRIC LOCALIZED MELECULAR ORBITALS

本文提出了最佳群对称定域分子轨道（OSlMOS）的概念，报道了OSlMOS的生成方法。OSlMOS满足分子对称、等价与正交；同时最佳逅近经典的非正交价键型轨道，并可作为MCSCf与CI方法中的单电子轨道。The concept and its generating method of optimum group spometric localized molecutarorbitals(OSLMOs)are proposed.OSLMOs have the same symrnetry and maximumoverlapping with corresponding V B orbitals,Moveover, they are con,completely orthogonal,thereFore the caiculations in MCSCF and Cl of large molecules could be siFnpllFied greatly byusing OSLMOs CGOs

Character Wave Functions in ConFiguration Interactions

提出了完全活性空间组态相互作用方法中对称化算符、本征基、特征矩阵、特征波函数等概念和将多电子波函救按空间与自旋对称分类的统一方法。按此法对称化算符并作用在特征波函数上，再按等价权空间求和即得全组态波函数。因对称性使组态函数中物理因子与几何因子完全分离，可消除了变分求解中多余的变量。特征基化学概念明确，直接对应给定的价键结构。The multi-electron conFigurational Functions in complete active space (CAS) are classiFied and characterized by weight vectors (occupation numbers of orbitals).Each conFiguration has a given weight vector.ConFiguration space invariant under molecular point group is called equivalent weight space.The Slater determinants are basis Functions in each equivalent weight space.The new concepts of symmetrization operators,character Slater bases, character matrices and character conFiguration Functions, and general generation methods of symmetrization Function (eigenFunction of S2 and irreducible representation of molecular point group) are proposed.According to this scheme,the Full conFigurational Functions are a sum of these Functions obtained by operating the symmetrization operator to character conFiguration Functions, thereFore, the physical Factors and geometric Factors in Full conFiguration Functions are completely separated and redundant variance parameters are removed due to symmetry adaptation.The character Slater bases are one-one correspondence with equivalent VB structure and have a deFine chemical signiFicance.This method might play an important role in the CI theory and calculations.国家自然科学基