饲草甜高粱分子育种与产业化

甜高粱(Sorghum dochna)是一种高产耐逆的C4植物.因其茎秆富含糖分、生物产量高、适口性好等特点,近年来又被发展为优质饲草作物.甜高粱主要生物学特性直接或间接地影响饲草的产量和品质,进而影响其作为饲草作物的发展潜能.本文综述了甜高粱种质资源筛选与重要性状遗传基础研究的最新进展,分析了甜高粱饲草产业发展案例,旨在积极推动甜高粱饲草产业的研究和应用

Construction of a Neotype Controllability Magnetic Targeting Restructuring Truncated Tissue Factor

目的:构建新型的具有可控性且能诱发动物血栓的栓塞剂磁靶向凝血蛋白,从而为动物血栓模型的建立提供新工具。方法:使用化学共沉淀法合成磁流体(; magnetic nanoparticles, MNPs),通过透析对其纯化后用超导量子干涉磁强针(; SQUID)测定其磁性能;利用基因工程方法表达截短组织因子( truncated tissue factor,tTF); (又称为凝血蛋白)并纯化与鉴定;采用戊二醛交联法构建磁靶向凝血蛋白(; MNPs-tTF),体外分析其磁控靶向性及凝血效力。结果:成功构建了磁靶向凝血蛋白MNPs-tTF,体外实验证实其保留有磁流体MNPs的磁控靶向; 性,以及凝血蛋白tTF的凝血效力。结论:成功构建了磁靶向凝血蛋白MNPs-tTF,为血栓模型动物的建立提供一种新工具。Objective: To establish a neotype controllability magnetic targeting; restructuring truncated tissue factor s for establish animal models of; thrombosis. Methods: Magnetic nanoparticles ( MNPs) were prepared by; chemical coprecipitation,and employed the superconducting quantum; interference device to characterized the MNPs magnetization. The; truncated tissue factor ( tTF) were expressed efficiently in E. coli and; purification by gene engineering technology. MNPs conjugated the tTF by; glutaraldehyde to compose MNPs-tTF. In vitro analysis the effects of; magnetic targeting and blood coagulation of MNPs-tTF. Result: The; magnetic targeting restructuring truncated tissue factor composites were; build successfully. They are reserve efficient coagulation effect and; magnetic targeted ability in vitro. Conclusion: We have successfully; prepared magnetic targeting thrombin system MNPs-tTF have been; successfully prepared,which maybe provide a basis for developing the; establish animal models of thrombosis.福建省科技计划重点项目; 福建省属公益类项

能源植物高粱基因组研究进展

回顾了高粱基因组学研究的发展进程,概述了初期组学数据的积累、参考基因组的破译及新一代测序技术和数据分析方法引领下的组学研究进展;介绍了高粱基因组的结构,从比较基因组学的角度,分析了高粱基因组的进化及其特性;探讨了高粱功能基因组的研究方法和研究进展,总结了已经发掘的高粱关键基因和遗传位点,对高粱组学数据资源进行了归纳。对高粱基因组学的发展方向进行了展望

Pigment extracted from fish skin and preparation process thereof

本发明涉及一种由鱼皮提取的天然色素及其制备方法，其特征是将鱼皮加入酸性溶液中进行浸提萃取，将萃取液过滤，大孔吸附处理，用酸性溶液清洗除去杂质及盐分，并在60℃～80℃的温度下用乙醇解析得到含色素解析液，将解析液在50℃～80℃的温度下减压浓缩得到液体色素。本发明的提取工艺科学合理，简单易行，得到的色素性能稳定，安全可靠，并对光、热均较稳定，除了含有人体必需的多种氨基酸、多种微量元素及矿物质外，对人体还具有一定的营养和保健作用，因此可以应用于食品、饮料和化妆品中

Methodology of China＇s national study on the evaluation, early recognition, and treatment of psychological problems in the elderly： the China Longitudinal Aging Study （CLAS）

认知和抑郁障是中国老年人常见的心理障碍,已成为严重的公共卫生问题,主要原因是快速的老龄化。为解决这一问题,中国政府资助了一项重大研究,以建立老年人常见心理障碍的早期识别、评估和非药物治疗标准。本文介绍了此研究的总体方法学。来自于8个省市的15个研究中心将从60岁以上老年人群中招募有代表性的研究样本,收集详细的病史资料,完成躯体和神经系统检查,进行全套神经心理测验和临床评定量表评估,采用DSM-IV定式临床访谈作出诊断。初始评估结束后第1年和第3年,将对研究对象进行随访评估。轻度认知损害(mild cognitive impairment,MCI)和亚临床抑郁者会被纳入随机对照研究,接受认知训练(MCI者)或团体认知行为治疗(亚临床抑郁者)。研究结果将用于估计老年入的认知和情感障碍的患病率,制定标准的筛查程序在全国推广应用,并促进采用针对性的干预措施来预防MCI发展为痴呆及老年亚临床抑郁进展为抑郁症。Summary： Cognitive and depressive disorders are common in elderly Chinese and are becoming an increasingly important public health problem, partly because of the rapid aging of the population. To help address this issue China＇s national government has funded a major study to establish national standards for the early identifica- tion, evaluation and treatment of common psychological disorders in the elderly. The present paper describes the overall methodology of this study. Fifteen centers in eight provinces will recruit representative samples of subjects aged 60 and over, collect a detailed history, conduct a physical and neurological examination, ad- minister a comprehensive battery of psychological tests, and carry out a diagnostic exam using the Structured Clinical Interview for DSM-IV （SCID）. These subjects will participate in follow-up evaluations one year and three years after the initial evaluation. Subsamples of subjects with mild cognitive impairment （MCI） and subclinical depression wilt be enrolled in randomized controlled trials of a cognitive training program （for MCI） or group cognitive behavioral therapy （for subclinical depression）. The results of the study will be used to estimate the prevalence of cognitive and affective disorders in the elderly, to develop a standard screening procedure for these conditions that can be promulgated nationally, and to promote the use of specific interventions that can prevent the development of dementia in persons with MCI and the development of depressive episodes in elderly individuals with subclinical depression