Technology Research of The Chemical Vapor Deposition Thick Tungsten Coating

传统的制备钨涂层方法包括：等离子喷涂、热喷涂、熔盐电镀、物理气相沉积、化学气相沉积等。其中，化学气相沉积以钨涂层纯度和致密度高的优点格外引人关注。近年来在国际热核聚变堆中将钨用于面向等离子体第一壁涂层材料已引起了世界范围内的关注和重视，其厚度要求大于1mm，且需要承受高能粒子及高热量冲击，对纯度和致密度的要求很高，化学气相沉积无疑是最具有潜力的方法。根据可掌握的资料，对化学气相沉积厚钨涂层的原料制备、涂层制备、涂层抗热负荷性能检测等系统性研究还开展得较少。 本文研究了六氟化钨的制备方法，并以自制高纯六氟化钨为原料，采用化学气相沉积方法成功得到了厚钨涂层。研究了沉积工艺对涂层的沉积速率、微观组...The traditional methods of preparing tungsten coatings comprise plasma spraying, thermal spraying, molten salt electroplating, physical vapor deposition, chemical vapor deposition, etc. Among them, chemical vapor deposition of tungsten coating is particularly concerned with the advantages of its high purity and high density. In recent years,using tungsten as plasma facing first wall coating materi...学位：工程硕士院系专业：材料学院材料科学与工程系_材料工程学号：X200719300

Temperature Rise Experiment and Control of Machine Tool Spindle

在静压轴承主轴的实验平台上开展了主轴温升试验,通过对主轴转速与温升试验数据的分析,得出了影响主轴温升的主要因素,并提出了控制主轴温升的一些措施。Temperature rise experiment is carried out on a machine tool spindle.The main factors influencing the spindle temperature rise are pointed out by analyzing the experiment data of spindle speed and temperature rise.Some useful measures of controlling temperature rise are then proposed in the paper.国家科技重大专项项目(编号:2010ZX04001-162

Thermal Deformation Control Strategies for a 5-axis CNC Tool Grinder

对五轴数控工具磨床进行热变形的控制是提高其加工精度的关键,在指出五轴数控工具磨床的主要热源后,分析了机床热变形对其加工精度的影响,综合误差防止与误差补偿两种方法提出了五轴数控工具磨床热变形控制的策略。Control of thermal deformation of 5-axis CNC tool grinder is imperative to improve its machining accuracy.The main heat sources are pointed out in this paper.The influences of grinder thermal deformation on machining accuracy are analyzed.Finally, some thermal deformation control strategies of 5-axis CNC tool grinder are proposed.国家“高档数控机床与基础制造装备”科技重大专项资助(2010ZX04001-162

磨床主轴热特性分析及热变形补偿策略

针对五轴数控可转位刀片周边工具磨床建立了砂轮-主轴-轴承-主轴箱的主轴部件有限元模型,分析了主轴部件的热源及其发热量的计算公式,通过有限元仿真计算得到磨床主轴的热稳态温度场和热变形量,进行了主轴热特性分析。在不增加温度、位移传感器的基础上提出了有效的主轴热变形补偿策略,实现刀片加工精度达到5μM的精度要求。国家科技重大专项(2010ZX04001-162

Spindle Vibration Test and Influence of Temperature Rise to the Vibration

在液体静压轴承主轴的实验平台上,采用激光位移传感器测量主轴在不同转速下的振动值。根据实验条件设计主轴温升试验方案,并测量主轴在指定转速运转15 MIn的温升情况以及振动量,研究温升对主轴振动的影响。On the experiment platform of hydrostatic bearing spindle,the spindle vibration value under different rotational speed measurement is obtained by the laser displacement sensor.The spindle temperature rise test solution is designed in accordance with experimental conditions,the temperature rise and vibration is measured at the specified speed running 15 minutes.Then the influence of the temperature rise on the spindle vibration is researched.国家科技重大专项项目(2010ZX04001-162

电诱导牙釉质表面羟基磷灰石涂层形成的研究

以含Ca(NO3)2、NH4H2PO4和NaNO3组成的溶液作为电解液,在人牙釉质表面电诱导制备了羟基磷灰石(HA)涂层。应用X射线衍射(XRD)﹑扫描电镜(SEM)和能谱分析(EDS)对形成涂层后的牙釉质样品进行分析和表征,研究了电解液初始pH值﹑电流密度和温度的变化对涂层的组成﹑结构和形貌的影响。研究结果表明这些因素对涂层的组分(HA)没有显著影响,而对涂层中HA晶体c轴的择优取向度的影响则较显著。当控制电解液的初始pH值为6﹑电流密度为0.5mA·cm-2﹑温度为55℃的时候,涂层中HA晶体沿c轴方向择优取向生长,且择优取向度和牙釉柱的HA较为接近

Application of Raman Spectroscopy for Analysis in Radiosensitivity of Total Protein of Nasopharygeal Carcinoma Cells

本文以鼻咽癌细胞株CnE2为放射敏感性的研究对象,经不同剂量X射线照射及不同时间培养后分别提取总蛋白,用共聚焦显微拉曼光谱仪检测其拉曼光谱。统计分析表明:被测样品的拉曼光谱中观察到一些可以归属于蛋白质物质的较为明显的基团频率振动峰;不同剂量的X射线照射后,总蛋白质的平均拉曼光谱与对照组谱形基本一致,但与对照组间的光谱存在着对应峰信号强度的不同。实验提示:照射后谱峰强度的增大或减小,提示着相关物质含量有所改变。分析照射后癌细胞总蛋白拉曼光谱的变化情况,结合数学统计方法,以探寻放射敏感性的特征拉曼标志,可以作为研究肿瘤放射敏感性的手段之一。To study the effects of total protein of nasopharyngeal carcinoma cell line CNE2 treated by different doses of X-ray irradiation.The total protein is extracted from the cell line and detected by confocal micro-Raman spectroscopy.Both t test and support vector machine are employed via SPSS and LIBSVM software packages for statistical analysis of Raman spectrum.The results show that several Raman bands assigned to total protein can be detected; and the X-ray irradiation have various effects on different components in total protein,and related to the radiation dose.It was indicated that in spite of no significant diversification on structures of protein,the content may be varied during irradiation.国家自然科学基金项目(11104030); 福建省自然科学基金项目(2011J01153

生物质基2,5-二甲基呋喃制备对二甲苯的研究进展?

对二甲苯(p-Xylene,pX)是一种十分重要的化工原料,其主要用途是生产对苯二甲酸(terephthalic acid,TA)和对苯二甲酸酯等聚合物单体产品。pX目前主要从石油化工路径制备得到。为了利用生物质资源绿色可持续地生产pX,从生物质基2,5-二甲基呋喃(2,5-Dimethylfuran,DMF)经Diels-Alder和脱水反应制备pX近年来逐渐成为研究热点。研究综述了近年来以生物质基DMF制备pX的研究进展,分析了该技术路线中催化体系和溶剂体系等方面的现状,并对生物质pX合成路径的发展趋势和前景进行展望

Development of Electrochemical Biosensor for Detection of PML/RARα Fusion Gene in Acute Promyelocytic Leukemia

针对急性早幼粒细胞白血病(APl)中PMl/rArα融合基因的碱基序列,设计了锁核酸(lnA)修饰的发夹结构捕获探针,结合信号探针构建新型的“三明治“电化学传感模式。信号探针末端修饰的生物素可与酶上的亲和素结合,通过检测酶催化H2O2氧化底物3,3',5,5'-四甲基联苯胺(TMb)产生的电化学信号,实现对靶序列的检测。该传感器可识别和定量检测PbS缓冲液中人工合成的PMl/rArα融合基因序列。结果表明,该传感器能很好地区分互补序列、单碱基及多碱基错配序列,杂交电流值与目标链浓度在1.0x10-11~1.6x10-10 MOl/l范围内呈较好的线性关系,检出限为1.0x10-13 MOl/l。同时,该新型传感器成功地用于无稀释人血清中PMl/rArα融合基因的检测,具有特异性强、灵敏度高和重复性好的优点,有望用于临床实际样品的检测,进而实现临床上急性早幼粒细胞白血病的早期诊断及预后判断。A novel DNA electrochemical probe(locked nucleic acid,LNA) was designed and involved in constructing an electrochemical DNA biosensor for the detection of PML/RARα fusion gene in acute promyelocytic leukemia(APL).This biosensor was based on a "sandwich" detection strategy,which involved a pair of LNA probes,e.g.hairpin capture probe and reporter probe.Streptavidin-HRP was bound to biotin labeled at the end of reporter probe via streptavidin-biotin affinity binding.In the presence of hydrogen peroxide(H2O2),HRP catalyzed the oxidation of the substrate 3,3′,5,5′-tetramethylbenzidene(TMB) to offer an enzymatically amplified electrochemical current signal for the detection of target DNA.This sensor was applied in the direct quantitative detection of synthetic PML/RARα fusion gene in PBS buffer.The results indicated that the biosensor showed an excellent specificity to distinguish the complementary sequence and different mismatch sequences.A linear relationship between the amperometric signal and the target concentration was obtained in the range of 1.0×10-11-1.6×10-10 mol/L with a detection limit of 1.0×10-13 mol/L.In addition,the biosensor was used for the determination of PML/RARα fusion gene in human serum samples without dilution with high sensitivity,selectivity and good repeatability.This method would be expected to use in real sample for further solving the actural problems of early diagnosis and prognosis monitoring of APL.863计划资助项目(2008AA02Z433);福建省高校产学研科技重点项目(2010Y4003);国家自然科学基金资助项目(20805006;20975021);福建省自然科学基金资助项目(2010J05019

Twinning in Nanocrystalline Ni by Severe Plastic Deformation

Deformation twinning is confirmed upon large plastic deformation in nanocrystalline (nc) Ni by transmission electron microscopy examinations. New and compelling evidence has been obtained for several twinning mechanisms that operate in nc grains, with the grain boundary emission of partial dislocations determined as the most proficient. Twinning in nc Ni may be interpreted in terms of molecular dynamics simulation based on generalized planar fault energy curves