138 research outputs found

    An Investigation on Learning Climate at Sport High Schools

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    Sport High Schools that activate in Turkey and where students who are skilled at sports have their secondary education are found to be suitable place to study on. In this study, it is aimed to study perception of teachers working and students studying in these institutions regarding learning climate. 342 teachers and 557 students that participated in the study voluntarily are considered to be the best universe taking part in the study in daily basis. In terms of data collection tool, Camur’s “Learning Climate Scale” with its Turkish adaptation in the year 2006 is used by considering its sub-dimensions. The participants are reached through sharing prepared research form in on-line social media sport high school groups. In order to find out learning climate perception of both teachers and students, determining statistics is used where, t-test and one-way variance analysis is used for comparing independent samples based on demographic features, and in order to find the relationships in the study, Pearson r relationship analysis is applied. In the end of the analyses made, it is found out that physical education and sports teachers have negative impression about learning climate in sport high schools (n=120, mean=3,304). Teachers of other fields working at sport high schools displayed highly negative impression (n=222, mean=2,828). Students studying at these institutions on the other hand displayed lesser levels of negative impression when compared to teachers (n=557, mean=3,637). As a result, when sport high schools are investigated based on learning climate, it is concluded that; both teachers and students do not meet at an appropriate education environment due to current status in those schools

    Interaction of anions with a newly characterized alpha carbonic anhydrase from Halomonas sp

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    The inhibition and characterization of the α-class carbonic anhydrase (CA, EC 4.2.1.1) from the Halomonas sp. are reported for the first time. The enzyme was purified 91-fold with a yield of 39%, and a specific activity of 600 U/mg proteins was obtained. It has an optimum pH at 7.5, an optimum ionic strength at 20 mM and an optimum temperature at 20 °C. The following anions, SCN(-), Br(-), Cl(-), I(-), [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text] and [Formula: see text] showed inhibitory effects on the hydratase activity of the enzyme. Sulfate, sulfide, azide, nitrate, nitrite and iodide exhibited the strongest inhibitory activity, in the micromolar range (KI-s of 5.5-15.5 µM). SCN(-), Br(-), Cl(-), [Formula: see text] were moderate inhibitors, whereas other anions showed only weak activities. Our findings indicate that these anions inhibit the Halomonas sp. CA (HmCA) enzyme in a similar manner to other α-CAs from mammals investigated earlier, but the susceptibility to various anions differs significantly between the Halomonas sp. and other organism CAs

    Simple methanesulfonates are hydrolyzed by the sulfatase carbonic anhydrase activity.

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    This study was financed by Turkish Republic Prime Ministry State Planning Organization (DPT), (Project no: 2010K120440) for (MS). Work from Supuran lab was financed by an FP 7 EU grant (Metoxia project)

    Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors

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    Deanship of Scientific Research at King Saud University [RGP-VPP-163

    Aortic distensibility and coronary artery bypass graft patency

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    <p>Abstract</p> <p>Background</p> <p>Aortic distensibility is an elasticity index of the aorta, and reflects aortic stiffness. Coronary artery disease has been found to be substantially associated with increased aortic stiffness. In this study we aimed to retrospectively analyze the association of angiographically determined aortic distensibility with the patency rates of coronary bypass grafts</p> <p>Methods</p> <p>The study was conducted in the Cardiology department of the Applied Research Centre for Health of Uludağ University. The coronary angiograms of 53 consecutive coronary bypass patients were analysed retrospectively. Aortic distensibility was calculated using the formula: 2 × (change in aortic diameter)/(diastolic aortic diameter) × (change in aortic pressure). The number of stenosed and patent bypass grafts and the patient characteristics like age, risk factors were noted.</p> <p>Results</p> <p>There were 44 male (83%) and 9 female (17%) cases. Eighteen cases had only one saphenous vein grafting. The number of cases with two, three and four saphenous grafting were 18, 11 and 1; respectively. In the control angiograms the number of cases with one, two, three and four saphenous vein graft obstruction were 15 (31.3%), 7 (14.6%), 1 (2.1%) and 1 (2.1%) respectively. The aortic distensibility did not differ in cases with and without saphenous graft occlusion (p > 0.05). Also left internal mammary artery (LIMA) graft patency was not related to the distensibility of the aorta (p > 0.05). We also evaluated the data for cut-off values of 50 and 70 mmHg of pulse pressure and did not see any significant difference between the groups in terms of saphenous or LIMA grafts.</p> <p>Conclusion</p> <p>In this study we failed to show association of angiographically determined aortic distensibility with coronary bypass graft patency in consecutive 53 patients with coronary artery bypass graft surgery (CABG).</p

    Postresectional lung injury in thoracic surgery pre and intraoperative risk factors: a retrospective clinical study of a hundred forty-three cases

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    <p>Abstract</p> <p>Introduction</p> <p>Acute respiratory dysfunction syndrome (ARDS), defined as acute hypoxemia accompanied by radiographic pulmonary infiltrates without a clearly identifiable cause, is a major cause of morbidity and mortality after pulmonary resection. The aim of the study was to determine the pre and intraoperative factors associated with ARDS after pulmonary resection retrospectively.</p> <p>Methods</p> <p>Patients undergoing elective pulmonary resection at Adnan Menderes University Medical Faculty Thoracic Surgery Department from January 2005 to February 2010 were included in this retrospective study. The authors collected data on demographics, relevant co-morbidities, the American Society of Anesthesiologists (ASA) Physical Status classification score, pulmonary function tests, type of operation, duration of surgery and intraoperative fluid administration (fluid therapy and blood products). The primary outcome measure was postoperative ARDS, defined as the need for continuation of mechanical ventilation for greater than 48-hours postoperatively or the need for reinstitution of mechanical ventilation after extubation. Statistical analysis was performed with Fisher exact test for categorical variables and logistic regression analysis for continuous variables.</p> <p>Results</p> <p>Of one hundred forty-three pulmonary resection patients, 11 (7.5%) developed postoperative ARDS. Alcohol abuse (p = 0.01, OR = 39.6), ASA score (p = 0.001, OR: 1257.3), resection type (p = 0.032, OR = 28.6) and fresh frozen plasma (FFP)(p = 0.027, OR = 1.4) were the factors found to be statistically significant.</p> <p>Conclusion</p> <p>In the light of the current study, lung injury after lung resection has a high mortality. Preoperative and postoperative risk factor were significant predictors of postoperative lung injury.</p

    VERITAS: Status and Highlights

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    The VERITAS telescope array has been operating smoothly since 2007, and has detected gamma-ray emission above 100 GeV from 40 astrophysical sources. These include blazars, pulsar wind nebulae, supernova remnants, gamma-ray binary systems, a starburst galaxy, a radio galaxy, the Crab pulsar, and gamma-ray sources whose origin remains unidentified. In 2009, the array was reconfigured, greatly improving the sensitivity. We summarize the current status of the observatory, describe some of the scientific highlights since 2009, and outline plans for the future.Comment: Presented at the 32nd ICRC, Beijing, 201
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