The Relationship Between Authentic Leadership and Entrepreneurship Orientation Perceptions in Exporting Companies with Different Export Performances

This study aims to examine the relationship between authentic leadership and entrepreneurship orientation perceptions in exporting companies with increasing and decreasing export performances. Subjective Scales were used in this study along with the Objective Scales. An Authentic Leadership and Entrepreneurial Orientation Subjective Scales were used, the scales were previously validated and reliability analyzes were carried out in Turkey. The convenience sampling of total 438 white-collar employees from 21 companies participated in the survey. Export Sales and Export Intensity Objective Scales, the most common financial measures of export performance indicators were used to identify the categories with increasing and decreasing export performances. The data collected and compiled from the Turkish Exporters Assembly (TIM).

Manufacturing and morphology of poly(-caprolactone) based microfibre webs for biomedical applications through airbrush technique

The objective of this study is to fabricate poly(-caprolactone) (PCL)-based micro/nano fibrous structures by using different types of solvents and nozzle sizes and to investigate the morphology of fabricated airbrushed structures for future biomedical applications. It is observed from the morphology and diameter of micro/nanofibres structures based on nozzle size, concentration of PCL and solvents, that these airbrushed biocompatible and biodegradable webs offer a potential in the medical field requiring direct, rapid and conformable applications

The frequency of Duchenne muscular dystrophy/Becker muscular dystrophy and Pompe disease in children with isolated transaminase elevation: results from the observational VICTORIA study

IntroductionElevated transaminases and/or creatine phosphokinase can indicate underlying muscle disease. Therefore, this study aims to determine the frequency of Duchenne muscular dystrophy/Becker muscular dystrophy (DMD/BMD) in male children and Pompe disease (PD) in male and female children with isolated hypertransaminasemia.MethodsThis multi-center, prospective study enrolled patients aged 3–216 months with serum alanine transaminase (ALT) and/or aspartate transaminase (AST) levels >2× the upper limit of normal (ULN) for ≥3 months. Patients with a known history of liver or muscle disease or physical examination findings suggestive of liver disease were excluded. Patients were screened for creatinine phosphokinase (CPK) levels, and molecular genetic tests for DMD/BMD in male patients and enzyme analysis for PD in male and female patients with elevated CPK levels were performed. Genetic analyses confirmed PD. Demographic, clinical, and laboratory characteristics of the patients were analyzed.ResultsOverall, 589 patients [66.8% male, mean age of 63.4 months (standard deviation: 60.5)] were included. In total, 251 patients (188 male and 63 female) had CPK levels above the ULN. Of the patients assessed, 47% (85/182) of male patients were diagnosed with DMD/BMD and 1% (3/228) of male and female patients were diagnosed with PD. The median ALT, AST, and CPK levels were statistically significantly higher, and the questioned neurological symptoms and previously unnoticed examination findings were more common in DMD/BMD patients than those without DMD/BMD or PD (p < 0.001).DiscussionQuestioning neurological symptoms, conducting a complete physical examination, and testing for CPK levels in patients with isolated hypertransaminasemia will prevent costly and time-consuming investigations for liver diseases and will lead to the diagnosis of occult neuromuscular diseases. Trial RegistrationClinicaltrials.gov NCT04120168

Bazı Bitki Büyüme Düzenleyicileri Uygulamalarının Vakkas Üzüm Çeşidine Ait ÇeliklerinKöklendirilmesi ve Fidan Randımanına Etkisi

Bu çalışma; 2021 yılında, Muş ili için önemli üretim ve gelir kaynağı olan Vakkas üzüm çeşidi çeliklerininköklenme performansı ve fidan randımanını belirlemek amacıyla yürütülmüştür. Çalışmada kullanılan çeliklereKontrol grubunun yanı sıra İndol-3-Bütirik Asit (IBA) ve İndol-3-Asetik Asit (IAA) bitki büyümedüzenleyicilerinden üç farklı uygulama dozları (1000 ppm, 2000 ppm ve 3000 ppm) olmak üzere toplam 7uygulama gerçekleştirilmiştir. Denemeye alınan bitki materyallerinde, sürgün sayısı (adet), sürgün uzunluğu(cm), yaprak sayısı (adet), kök sayısı (adet), kök uzunluğu (cm), kök yaş ağırlığı (gr), kök gelişim seviyesi (1-4skalası), sürmüş/sürmemiş çelikler ve fidan randımanı (%) bakımından değerlendirilmiştir. Çalışma sonucundaelde edilen fidanlarda ortalama sürgün sayısı (2 adet), kök sayısı (46.67 adet), kök uzunluğu (17.63 cm), kök yaşağırlığı (9.30 gr), kök gelişim seviyesi (3.67), ve fidan randımanında (%92) en iyi başarı 1000 ppm IBAuygulamasından elde edilmiştir. Ortalama sürgün uzunluğu (23.33 cm) ve yaprak sayısında (18.33 adet) enbaşarılı uygulama 2000 ppm IBA uygulaması olarak tespit edilmiştir. Sonuç olarak, IBA dozlarının uygulandığıçeliklerde kontrol grubu ve IAA dozlarının uygulandığı çeliklere kıyasla daha olumlu sonuçlar alındığı tespitedilmiştir

Manufacturing and morphology of poly(ε-caprolactone) based microfibre webs for biomedical applications through airbrush technique

38-42The objective of this study is to fabricate poly(ε-caprolactone) (PCL)-based micro/nano fibrous structures by using different types of solvents and nozzle sizes and to investigate the morphology of fabricated airbrushed structures for future biomedical applications. It is observed from the morphology and diameter of micro/nanofibres structures based on nozzle size, concentration of PCL and solvents, that these airbrushed biocompatible and biodegradable webs offer a potential in the medical field requiring direct, rapid and conformable applications

Association of rs62063857 Variant of the Saitohin Gene with Parkinson's Disease

Saitohin gene found within the tau gene is thought to play a role in the pathogenesis of neurodegenerative diseases. The rs62063857 polymorphism originally found in the saitohin gene seems to be the responsible SNP in this event. This polymorphism is studied mostly in patients with Alzheimer's disease. Data on Parkinson's disease are scarce. Therefore, we examined the rs62063857 polymorphism in 583 Parkinson's disease patients (347 male and 236 female) and 396 healthy controls (238 male and 158 female) by a polymerase chain reaction and restriction fragment length polymorphism method to see whether it was associated with Parkinson's disease from the City of Istanbul, Turkey. The G allele frequency was 22 % in overall controls and 16 % in Parkinson's disease patients. In this study, the saitohin rs62063857 polymorphism was associated with Parkinson's disease (chi 2 = 16.765; P = 0.000). Individuals with the AA genotype showed 1.7-fold increased risk for Parkinson's disease (chi 2 = 16.680; P = 0.000), whereas individuals with the AG genotype revealed protection against Parkinson's disease (chi 2 = 14.554; P = 0.000). After the stratification analysis according to gender, both male and female PD patients showed association with the alleles and genotypes of the rs62063857 polymorphism of the saitohin gene (chi 2 = 9.476, P = 0.009; chi 2 = 7.593, P = 0.022, respectively). When the Parkinson's patients were divided into two groups with regard to onset of the disease, both groups showed association with the disease. The Parkinson's patients with disease onset below 65 years of age showed 1.8-fold increased risk for the disease. The Parkinson's patients with disease onset over 65 showed more robust association with a 2.051-fold increased risk for the disease. Consequently, the rs62063857 polymorphism of the saitohin gene is a genetic risk factor for Parkinson's disease. Hence, this polymorphism may play a role in the etiology of Parkinson's disease

Spatial clustering and hot spot analysis of the COVID-19 pandemic in Malatya province

It was revealed that what caused the disease that emerged with respiratory symptoms (fever, cough, shortness of breath) towards the end of 2019 in Wuhan city of China's Hubei province, and later named as COVID-19 by WHO was SARS-CoV-2 virus. The COVID-19 epidemic affected Turkey very quickly as it did the entire world, and the first official case in Turkey was detected in March 2020. In this study, how the COVID-19 cases are clustered in the districts of Malatya and the structure of this clustering as well as whether the cluster has changed over time was revealed by using the spatial exploratory analysis approach. For this purpose, Global and Local Moran I statistics that measure spatial interaction were used. For the hot spot analysis, Getis-Ord’s Gi* statistic was used. Moran I, which measures the spread of COVID-19 among districts, is statistically significant, and the spread effect is close to medium, although not very strong. It has been determined that Yazıhan and Akçadağ districts are the riskiest districts on average as of the period under consideration according to Lokal Moran I statistics. According to the Getis-Ord’s Gi* statistics, Yazıhan district is the one that is most suitable for the spread of the epidemic for Malatya, again being a hot spot location. It has been observed that Yazıhan district is frequently in the hot spot according to the monthly analysis of the Gi*statistics. In this context, it is important for Yazıhan district to increase the necessary measures in the coming periods and to make efforts to raise awareness of the citizens