Fractal tools in terrorist and financial crime prevention

Information society imposes globalization and universality of values. In these circumstances, terrorism, institutional political violence which targets trying to achieve the morbid fear of provoking a spectacular way, inappropriately given conditions, becomes a real threat not only to the nations but also to politics on the global level. In 1996, the International Monetary Fund estimated that 2–5% of the worldwide global economy involved laundered money. Today, intelligence activities in preventing and combating terrorism include financial investigations and money laundering for the purpose of financing terrorism, resulting in broadening of the scope of data to the level which makes it impossible for human logical evaluation. Technologies development that enables increasing capacity of speed and the amount of data processing has enabled defining, analyzing and exploring more and more models. This led to the idea of computer experiments and simulations trying to get to more complex planning and forecasting for the purpose of countering terrorism and “dirty” money transaction, as highly dangerous, complex and variable phenomena. This presentation aims at quotation the wide spectrum of mathematically founded fractal concepts suited to generate computer models of anti-terrorist activities. In this sense, the logistic behind the items connected with detecting and recognizing degree of terroristic threat by comparing fractal structure of people’s faces, fast search through the databases of faces and fingerprints. The speed of searching processes is of vital importance which promotes the crucial importance of compression and data reduction with preservation of regularity. Especially important are analytic forecasting of missing visual data and forms, to supplement the empirical evidences and records. All these operations are possible with higher degree of knowledge utilization and adaptation of virtual reality in the fight against terrorism and different forms of money laundering. The results indicate that the achievements implementation of the concept of fractals depends on substantial prior knowledge, environmental influences, subsystem integration, decentralization and synchronization, and allows us to come up with similar high information technology models, but not necessarily to enable identification of the authentic features of the various anomalies that result in objectively a social consequences. In this sense, we conclude that the application of information technology in the fight against terrorism, based on the concept of fractals has its place in the arsenal of anti-terroristic prevention

Laboratorijske analize krvnog seruma i urina pasa sa akutnom renalnom insuficijencijom izazvanom gentamicinom

The use of aminoglucoside antibiotics can be a potential risk for renal parenchyma damage and consequently acute renal failure (ARF). ARF is a syndrome that develops from progressive nephron damage resulting in the loss of renal function. Numerous experimental models have been used to study acute renal failure mainly describing histo-pathological changes in the structure of this organ. Our investigations were conducted in order to evaluate the functional capacity of kidneys in dogs with ARF induced by application of gentamicin in high doses of 80 mg/kg/24 , during 7 days. For that purpose, physico-chemical properties of the urine, concentrations of relevant parameters in the sera and urine and endogenous creatinine clearance were estimated. Our results indicate that gentamicin, in doses 20 times higher than therapeutic ones, causes progressive ARF starting from the 3 day of application.Pod određenim uslovima upotreba aminoglukozidnih antibiotika može predstavljati potencijalni rizik za nastanak oštećenja u parenhimu bubrega i posledične akutne renalne insuficijencije (ARI). ARI je sindrom koji nastaje usled progresivnog propadanja nefrona, što dovodi do gubitka sposobnosti bubrega da obavljaju svoju funkciju. Za proučavanje akutne renalne insuficijencije korišćen je veći broj različitih eksperimentainih modela pri čemu su uglavnom opisivane histopatološke promene u ovom organu. Naša ispitivanja su imala za cilj da se utvrdi funkcionalna sposobnost bubrega pasa u toku akutne renalne insuficijencije, izazvane visokim dozama gentamicina (80 mg/kg/24h), aplikovanim tokom 7 dana. U tom cilju su određivane fizičko-hemijske karakteristike mokraće, koncentracija relevantnih sastojaka u serumu i urinu kao i klirens endogenog kreatininina. Dobijeni rezultati ukazuju da se dozama gentamicina, dvadeset puta većim od terapijskih, već posle tri dana aplikacije izaziva ARI koja ima progresivan tok do kraja ogleda

Biohemijske promene u krvnom serumu pasa tretiranih fenobarbitonom

Despite being described as the safest antiepileptic drug of first choice the presented literature data are much varied as far as dog blood serum biochemical parameters are considered. The aim of this study was to investigate the effect of phenobarbitone at different per os doses on the values of selected blood serum biochemical parameters in dogs during both short and long term application. The study was conducted on 30 dogs of different races, both sexes, ranging from 2 to 8 years of age. A total of 15 healthy and 15 dogs suffering from idiophatic epilepsy were observed. During the short term per os application of phenobarbitone (given at 3 week intervals) to the healthy population in varied doses a statistically significant increase in ALT and AP was recorded. Application of 16 mg/kg/day of phenobarbitone to the healthy population during 14 days resulted in a significant increase of ALT and AP. This increase was dependant on the duration of the treatment. During chronic application of phenobarbitone to dogs suffering from idiopathic epilepsy a significant increase in values of AP and ALT depending on the given dose was recorded. In two of the studied epileptic dogs treated with high therapeutic doses of phenobarbitone clinical signs of hepatotoxicity were recorded. Hepatotoxicity resulted in decreased albumin and total protein concentrations, as well as increased blood serum total bilirubin, AST, ALP and AP. The obtained results indicate that a long term application of phenobarbitone at high therapeutic doses can cause hepatotoxicity. However, there was no relationship between phenobarbitone dosage and duration of therapy and blood glucose, urea, creatinine, total proteins, albumins, total bilirubin, triglycerides and cholesterol.Iako označen kao antiepileptik prvog izbora i veoma bezbedan lek, u literaturi su prezentovani različiti podaci o uticaju fenobarbitona na vrednosti biohemijskih parametara krvnog seruma kod pasa. S obzirom na to, cilj ovog istraživanja bio je da se ispita uticaj fenobarbitona pri različitim per os dozama na vrednosti biohemijskih parametara krvnog seruma kod pasa, tokom kratkotrajne i dugotrajne aplikacije. Istraživanje je sprovedeno na 30 pasa različitih rasa, oba pola, starosne kategorije od dve do osam godina, od kojih su 15 bili zdravi psi a 15 psi oboleli od idiopatske epilepsije. Tokom kratkotrajne per os aplikacije fenobarbitona (intervali od po tri nedelje) zdravoj populaciji pasa pri različitim per os dozama, u krvnom serumu je registrovano značajno povećanje aktivnosti ALT i vrlo značajno povećanje aktivnosti AP u zavisnosti od doze leka. Aplikacija fenobarbitona u dozi od 16 mg/kg/dnevno tokom 14 nedelja zdravoj populaciji pasa ukazala je, na vrlo značajno povećanje aktivnosti ALT i AP u zavisnosti od dužine trajanja aplikacije. Tokom hronične aplikacije fenobarbitona psima obolelim od idiopatske epilepsije, ustanovljeno je statistički vrlo značajno povećanje aktivnosti AP i ALT u krvnom serumu u zavisnosti od doze leka. Kod dve jedinke u bolesnoj grupi pasa pri visokim terapeutskim dozama fenobarbitona registrovana je hepatotoksičnost, što je dovelo do statistički značajnog smanjenja koncentracije albumina i ukupnih proteina, statistički značajnog povećanja koncentracije ukupnog bilirubina, statistički značajnog povećanja aktivnosti AST i statistički vrlo značajnog povećanja aktivnosti ALT i AP u krvnom serumu Dobijeni rezultati ukazuju da dugotrajna aplikacija fenobarbitona, pri visokim terapeutskim dozama može izazvati hepatotoksičnost. Nije ustanovljeno postojanje veze između koncentracije glukoze, uree, kreatinina, ukupnih proteina, albumina, ukupnog bilirubina, triglicerida i holesterola u krvnom serumu pasa sa per os dozom fenobarbitona, niti sa dužinom trajanja terapije

Information and learning in processing adjective inflection

​We investigated the processing of inflected Serbian adjective forms to bring together quantitative linguistic measures from two frameworks – information theory and discrimination learning. From each framework we derived several quantitative descriptions of an inflectional morphological system and fitted two separate regression models to the processing latencies that were elicited by inflected adjectival forms presented in a visual lexical decision task. The model, which was based on lexical distributional and information theory revealed a dynamic interplay of information. The information was sensitive to syntagmatic and paradigmatic dimensions of variation; the paradigmatic information (formalized as respective relative entropies) was also modulated by lemma frequency. The discrimination learning based model revealed an equally complex pattern, involving several learning-based variables. The two models revealed strikingly similar patterns of results, as confirmed by the very high proportion of shared variance in model predictions (85.83%). Our findings add to the body of research demonstrating that complex morphological phenomena can arise as a consequence of the basic principles of discrimination learning. Learning discriminatively about inflectional paradigms and classes, and about their contextual or syntagmatic embedding, sheds light on human language-processing efficiency and on the fascinating complexity of naturally emerged language systems

Reconstruction of the mandible with an autogenous corticocancellous bone graft and fibrin glue: An animal experiment

This paper reports on an experimental animal study evaluating a method of mandibular reconstruction in dogs using autogenous corticocaneclous bone graft and fibrin glue. Eight animals underwent a resection at the mandibular body and primary reconstruction was carried out using osteosynthesis plates and screws. The defect was bridged with an autogenous particulate bone graft from the anterior iliac crest. To accelerate bone healing, fibrin glue (FG) was mixed with particulate bone graft. The hypothesis of this study was based on the presumption that bone healing, in segmental reconstruction of the dog mandible with a particulate cancellous bone graft mixed with FG, would be successful. All dogs had eventful healing. The histological results were less favorable with regard to bone remodeling than the results obtained in similar experiments with a particulate corticocancellous bone graft

Određivanje koncentracija metamizol-natrijuma u inflamiranim zglobovima svinja posle intravenske i elektroforetske aplikacije

Concentrations of the NSAID metamizol sodium (MmNa) in the synovial fluid and hyaline cartilage of inflamed knee and elbow joints of pigs after i.v. application and iontophoresis (IPh) were investigated. The research was conducted on 14 male pigs divided equally into two experimental groups and exposed to artificial inflammation of knees and elbows prior to the application of MmNa. The first group (A) was administered 2.5 g (twice the maximum therapeutic dose) MmNa intravenously, whilst the second group (B) was exposed to the same dose, but applied by IPh into contralateral knee and elbow joints. Four hours after the application of MmNa biopsies of the affected knee and elbow joints were performed. The average concentration of MmNa in the synovial fluid of inflamed joints in group A was 9.81±1.96μg/g, while in group B was 170.66±2.07 μg/g, being 17 times higher. The average concentration of MmNa in the hyaline cartilage was 2.29±1.16μg/g following i.v. administration and 98.36±21.58μg/g after IPh, i.e. approximatelly 43 times higher. This led to the conclusion that IPh of MmNa, resulting in incomparably higher concentrations in inflamed joints without any adverse systemic effects, has an advantage over i.v. application.U sinovijalnoj tečnosti i hijalinoj hrskavici inflamiranog kolenog i lakatnog zgloba svinja određivane su koncentracije metamizol-natrijuma (MmNa) aplikovanog i.v. i putem elektroforeze. Arteficijelno zapaljenje kolena i lakta prasadi izazvano je terpentinskim uljem. Metamizol-natrijum je primenjen u dozi od 2.5 g u prvoj grupi prasadi intravenski, a u drugoj putem elektroforeze u kontalateralni koleni i lakatni zglob. Četiri sata posle aplikacije MmNa urađena je biopsija tretiranih zglobova. Prosečna koncentracija MmNa u sinovijalnoj tečnosti inflamiranih zglobova prasadi posle i.v. aplikacije iznosila je 9,81±1,96μg/g, a posle elektroforeze bila je 170,66±2,07μg/g tkiva, odnosno oko 17 puta viša. Izmerena prosečna koncentracija MmNa u hijalinoj hrskavici iznosila je 2,29±1,16μg/g posle i.v. aplikacije i 98,36±21,58μg/g posle aplikacije elektroforezom, odnosno oko 43 puta više. Zaključujeno je da MmNa primenjen elektroforezom postiže statistički veoma značajno više prosečne koncentracije u inflamiranim zglobovima u odnosu na i.v. aplikaciju. Primena MmNa elektroforezom ima značajnu prednost nad i.v. aplikacijom ovog leka ne samo zbog postizanja značajno viših koncentracija u inflamiranim zglobovima, već i zbog izostajanja sistemskih neželjenih reakcija

Significance of survivin immunoreactivity and morphometric analysis of HPV-induced cervical dysplasia

Genomic integration of high-risk human papilloma virus in the nucleus of cervical epithelial mucosal cells leads to epithelial dysplasia. The aim of this study was to determine the relevance of correlation between epithelial survivin expression and the degree of human papilloma virus (HPV)-induced cervical epithelial dysplasia, and to establish the significance of morphometric analysis of the nuclear area in the assessment of the degree of cervical dysplasia. This retrospective study included 99 women with primary, previously untreated lesions, and colposcopic findings indicating dysplasia, in whom a cytological test by Papanicolaou method was interpreted according to the Bethesda criteria as lowgrade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL), and atypical squamous cells of undetermined significance (ASCUS). We performed human papilloma virus (HPV) typing by PCR for evidence of viruse types 16, 18, 31, 33. After biopsy of the cervical mucosa, we performed hematoxylin-eosin (H-E) and Periodic Acid Schiff (PAS) staining, and immunohistochemical and morphometric analysis of tissue samples. The control group consisted of 12 women without dysplasia and without a verified infection of cervical high-risk HPV. A high statistical correlation between the degree of dysplasia and expression of survivin was found in patients with different types of cervical dysplasia (p = 0.003). We observed a high statistical difference between the area of nuclei at different degrees of cervical dysplasias (p = 0.000). The high-grade cervical dysplasia had a more than 2-fold higher level of ranking in comparison to low-grade dysplasia, and a more than 10-fold higher ranking than the control group without cervical dysplasia

The procedure proposal for order pick area design

Problem definiranja komisione zone pri projektiranju skladišta je vrlo složen zadatak koji zahtijeva opsežnu analizu i štovanje niza različitih faktora. Konfiguracija komisione zone je u funkciji niza kriterija koji se razlikuju po značaju i utjecaju pri donošenju odluke. U ovom članku predložena je hijerarhijska iterativna procedura za tehnološko uobličavanje komisione zone, čija primjena omogućava minimizaciju troškova uz štovanje zahtjevane razine servisa. Procedura obuhvaća generiranje alternativnih koncepcija komisione zone, određivanje njene veličine i procjenu relevantnih troškova primjenom parcijalnih analitičkih metoda.The problem of order pick area (OPA) defining during warehouse designing is a very complex task that requires a full set of analysis and trade offs of different factors. Configuration of OPA is the function of numerous criteria, which differ by their significance and impact on decision-making. In this paper, hierarchy iterative procedure for technological configuration of picking area is proposed, whose appliance enables cost minimization respecting the required service level. The procedure includes generating alternative concepts, determinating size of OPA and evaluating relevant costs of certain concepts using partial analytical methods

The procedure proposal for order pick area design

Problem definiranja komisione zone pri projektiranju skladišta je vrlo složen zadatak koji zahtijeva opsežnu analizu i štovanje niza različitih faktora. Konfiguracija komisione zone je u funkciji niza kriterija koji se razlikuju po značaju i utjecaju pri donošenju odluke. U ovom članku predložena je hijerarhijska iterativna procedura za tehnološko uobličavanje komisione zone, čija primjena omogućava minimizaciju troškova uz štovanje zahtjevane razine servisa. Procedura obuhvaća generiranje alternativnih koncepcija komisione zone, određivanje njene veličine i procjenu relevantnih troškova primjenom parcijalnih analitičkih metoda.The problem of order pick area (OPA) defining during warehouse designing is a very complex task that requires a full set of analysis and trade offs of different factors. Configuration of OPA is the function of numerous criteria, which differ by their significance and impact on decision-making. In this paper, hierarchy iterative procedure for technological configuration of picking area is proposed, whose appliance enables cost minimization respecting the required service level. The procedure includes generating alternative concepts, determinating size of OPA and evaluating relevant costs of certain concepts using partial analytical methods

Uticaj odgajivačkog područja i godine na osobine mlečnosti bikovskih majki simentalske rase

Cows which represent top of the genetic value of the population in regard to their traits are chosen for bull dams. Selection is based on origin, production performance (quantity of milk, milk fat and protein content), milking/dairy traits, reproductive indicators, exterior and linear type scores. This study included 292 cows of Simmental breed selected for bull dams on the territory of Republic of Serbia during one year. Selection of cows for herd of bull dams was done after finalized first and subsequent lactation. In this study, the effect of region and year of calving on milk traits is presented. Applying the method of least squares average value of milk production was obtained - 5.754,49 kg, milk fat content - 3,98% and quantity of milk fat - 230,24 kg. Regions had statistically highly significant effect (P (lt) 0,01) on all investigated milk traits. Year of calving showed no statistically significant effect on milk yield, yield of milk fat and content of milk fat (P>0,05).Za bikovske majke se odabiraju krave koje prema osobinama predstavljaju vrh genetske vrednosti populacije. Izbor se vrši na osnovu porekla, proizvodnih osobina (količina mleka, sadržaj mlečne masti i proteina), muznih osobina, reproduktivnih pokazatelja, eksterijera i linearnih ocena tipa. Ovim istraživanjem je obuhvaćeno 292 krave simentalske rase odabrane za bikovske majke na području Republike Srbije u toku godine. Odabiranje krava u zapat bikovskih majki izvršeno je posle završene prve, odnosno na osnovu sledećih laktacija. U radu je ispitan uticaj odgajivačkog područja i godine telenja na osobine mlečnosti. Koristeći metod najmanjih kvadrata dobijene su prosečne vrednosti proizvodnje mleka 5.754,49 kg, sadržaja mlečne masti 3,98% i količine mlečne masti 230,24 kg. Regioni su imali statistički visoko značajan uticaj (P (lt) 0,01) na sve ispitivane osobine mlečnosti. Na osobine prinosa mleka, mlečne masti i sadržaja mlečne masti, godina telenja nije ispoljila statistički značajan uticaj (P>0,05)