Effectiveness of Pet/Ct in Evaluation of the Lymphoma

DergiPark: 640241tmsjAims: Prognosis and survival of Hodgkin lymphoma have been improved dramatically by the development of treatments as well as the sensitivity of evaluation tools. In this case report, we aimed to emphasize the importance of positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography in the initial staging of Hodgkin’s lymp-homa, evaluating the response to treatment, and to demonstrate residual tissue or recurrence. Case Report: A 25-year-old male patient presented to Trakya University Hospital with swelling in the right groin and was diagnosed with Hodgkin’s lymphoma. Positron emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography scan was used for initial staging and assessment of response to treatment. Conclusion: Positron emission tomography is a feasible imaging modality for the evaluation of lymphomas. It is sensitive to detect minimal recurrence as well as alterations of lesions’ metabolic activity. Keywords: Positron emission tomography, lymphoma, hodgkin diseas

Population abundance and growth parameters of an exotic bivalve species, Anadara kagoshimensis, in the Southwestern Black Sea

Blood cockle (Anadara kagoshimensis ) is an Indo-Pacific species that later entered the Black Sea. The abundance of A. kagoshimensis, which is not subjected to commercial fishing, is important in terms of food competition with other bivalvia species. Baby clam (Chamelea gallina) together with the A. kagoshimensis are dominant bivalve species found in the sandy and muddy areas off the coastal waters of the Black Sea. In this study, specimens of A. kagoshimensis have been recognized by morphological analysis and also confirmed by molecular characterization. Furthermore, the abundance and growth parameters of A. kagoshimensis were investigated in the Southwestern Black Sea. Blood cockles were sampled between February 2011 and December 2012, seasonally. According to the Von Bertalanffy Growth Parameters (VBGP) the results were L infinity = 81.96 mm, K = 0.32 year-1, t0 = -0.22 year, and nonseasonal L infinity = 84.32 mm, K = 0.31 year-1, t0 = -0.21, WP = 0.65, ts = 0.15. The growth pattern showed the slope [b] = 2.96-3.01 in 2011 and 2012. The stock size was estimated according to two different years in 5 different subareas (Cide, Inebolu, Turkeli, Ayancik, and Sarikum) and by 4 different strata (0-5 m, 5-10 m, 10-15 m, and 15-20 m). Considering subareas, the A. kagoshimensis population in all subareas increased significantly in a single year. Compared to other regions, Inebolu was the main highly distributed area of the A. kagoshimensis, and also the estimated stock size was the highest in the region. Due to food competition with other commercial species (mainly Chamelea gallina) A. kagoshimensis is an ecology important species for the Southern Black Sea habitats. It is aimed to make contributions to Good Environmental Status (GES) and fisheries management in the region

Type B Lactic Acidosis in A Child with Relapsed non-Hodgkin Lymphoma

Lactic acidosis is a major cause of metabolic acidosis in critically ill patients. Herein we report a child with relapsed non-Hodgkin’s lymphoma admitted to the pediatric intensive care unit (PICU) with profound lactic acidosis. On admission, he was treated with fluid replacement and a vasopressor, followed by continuous veno-venous hemodiafiltration to correct acidosis. As lactic acid levels remained high despite all treatments, thiamine was added to the therapy, which did not influence metabolic status either. Lactic acidosis could only be corrected by aggressive chemotherapy during his stay in the PICU. The patient died on the 68th day of PICU admission due to underlying progressive disease. Clinicians should start aggressive chemotherapy as soon as possible in patients with a recurrence or advanced cancer who have type-B lactic acidosis

The Effect of Tracheostomy Timing on Clinical Outcomes in Children

Introduction:Optimal timing for tracheostomy in children is not well defined. Our aim is to examine the pre-tracheostomy morbidities, indications and association of early tracheostomy on clinical outcomes.Methods:This retrospective cohort study included all patients who underwent tracheostomy in the Dokuz Eylül University Pediatric Intensive Care Unit (ICU) between January 2012 and September 2020. We categorized patients into the early and late tracheostomy groups according to time on a mechanical ventilator before tracheostomy using a cut-off of 14 days. Pre-tracheostomy morbidities [ventilator associated pneumonia (VAP), central line associated bloodstream infection], indications and clinical outcomes (including length of ICU and hospital stay, incidence of VAP and mortality) were compared between early and late groups.Results:Of the 104 patients undergone tracheostomy, 90 were included in the study: Thirty patients in the early group, 60 patients in the late group. Tracheostomy rate of our unit was 6.06%, with a median ventilator time before tracheostomy of 20 days. VAP and lung tissue disease indication for tracheostomy independently increased pre-tracheostomy mechanical ventilation time by 8 and 12.6 days, respectively. There was no statistically significant difference in VAP rate after tracheostomy, successful decannulation and mortality between early and late group. Early group had lower post-tracheostomy ICU-length of stay (LOS) (8.5 vs. 13 days p=0.041) and total ICU-LOS (17.5 vs. 45 days p<0.001). Controlling for age, tracheostomy indication, central line associated bloodstream infection and VAP; tracheostomy timing was independently associated with ICU-LOS. Late tracheostomy timing increased the ICU-LOS by 10.7 days (p=0.041).Conclusion:Our results suggest that early timing of tracheostomy is associated with reduced ICU-LOS and VAP in children, consistent with the current literature

Type B Lactic Acidosis in A Child with Relapsed non-Hodgkin Lymphoma Nüks non-Hodgkin Lenfomalı Bir Çocukta Tip-B Laktik Asidoz

Lactic acidosis is a major cause of metabolic acidosis in critically ill patients. Herein we report a child with relapsed non-Hodgkin’s lymphoma admitted to the pediatric intensive care unit (PICU) with profound lactic acidosis. On admission, he was treated with fluid replacement and a vasopressor, followed by continuous veno-venous hemodiafiltration to correct acidosis. As lactic acid levels remained high despite all treatments, thiamine was added to the therapy, which did not influence metabolic status either. Lactic acidosis could only be corrected by aggressive chemotherapy during his stay in the PICU. The patient died on the 68th day of PICU admission due to underlying progressive disease. Clinicians should start aggressive chemotherapy as soon as possible in patients with a recurrence or advanced cancer who have type-B lactic acidosis