Relationship Between Gestational Diabetes and Thyroid Hormones in Pregnant Women

Objective:Gestational diabetes and thyroid disorders are common disorders during pregnancy. This study investigated the relationship between gestational diabetes and thyroid hormone levels in pregnant women.Method:This single-center study was conducted by analyzing retrospectively 190 pregnant women who admitted to the private internal medicine clinic between March 2019 and December 2022. Ninety pregnant women diagnosed with gestational diabetes mellitus (GDM) and one hundred pregnant women without GDM diagnosis were included in the study. The relationship between thyroid markers [thyroid-stimulating hormone (TSH) and free thyroxine hormone 4 (fT4)] and gestational diabetes was examined.Results:Results did not show a statistically significant association between case and control regarding age and body mass index (p-value >0.05). There was a statistically significant difference between groups regarding TSH (p-value 0.05). There was a statistically meaningful association between healthy women and women with GDM in terms of subclinical hypothyroidism frequency (p-value <0.05).Conclusion:TSH levels, fasting blood glucose and hypothyroidism are among the risk factors for the development of the gestational diabetes

MİNERAL TRİOXİDE AGGREGATE MTA 'İN İNTRAKORONAL AĞARTMA UYGULAMALARINDA BARİYER MATERYALİ OLARAK KULLANIMININ KARŞILAŞTIRILMALI DEĞERLENDİRİLMESİ

Bu çalışmanın amacı; mineral trioxide aggregate’in MTA intrakoronal ağartma uygulamalarında izolasyon bariyer materyali olarak kullanımının, cam iyonomer siman ve çinko fosfatsiman ile karşılaştırılmalı olarak değerlendirilmesidir. Çalışmada, yeni çekilmiş otuz sekiz adetçürüksüz daimi tek köklü insan dişi kullanıldı. Kökkanalları temizlenip, Step-Back tekniği ilegenişletildi, daha sonra AH plus ve guta-perka iledolduruldu. Bu işlemlerden sonra, dişler rasgele üçdeney grubu, bir pozitif kontrol ve üç negatifkontrol gruplarına ayrıldı. Kök kanal dolgularıüzerine bariyer materyali olarak ortalama 2mmkalınlığında cam iyonomer siman, çinko fosfatsiman ve MTA’dan oluşan deney materyalleriyerleştirildi. Negatif kontrol gruplarındaki dişlereağartma işlemi uygulanmamış, pozitif kontrolgrubu örneklerine ise bariyer materyali yerleştirilmemiştir. Bu işlemlerin ardından, deneygruplarındaki tüm dişlere sodyum perborat ve sukarışımından oluşan ağartma ajanı üç haftaboyunca, birer hafta arayla uygulandı. Ağartmauygulamalarından sonra, dişler % 0,5’lik bazik fuksin boyasında 24 saat bekletildi. Tüm örnekler mesio-distal yönde ikiye ayrılıp, boya penetrasyonu stereomikroskop altında değerlendirildi . Her ne kadar istatistiksel olarak MTA ve çinko fosfat siman grupları arasında anlamlı szııntı farkı olmasa da p>0.05 , bulgularımız MTA’nın daha az sıznıtı gösterdiği yönündedir. Cam iyonomer simanın MTA ve çinko fosfat simana göre istatistiksel olarak daha fazla sızıntı sergilediği görülmüştür

Determination of endocervical chlamydia trachomatis infection in pregnant women in the early travail using enzyme immune assay (EIA)

Erken travay saptanan gebelerde endoservikal Chlamvdia infeksiyonu enzim immun assay (EIA) (Chlamyfast) kullanılarak araştırılmıştır. Kontrol grubu olarak erken travayda olmayan 30 gebede de endoservikal Chlamvdia infeksiyonu araştırılmıştır. Erken travaydaki gebelerde Chlamvdia prevalansı % 13.3, kontrol grubunda da bu oran % 13.3 olarak saptanmış; her iki grup arasında endoservikal Chlamvdia pozitifliği bakımından fark bulunmamıştır. C. trachomatis infeksiyonunun erken travay ve erken doğuma olan katkısı tartışılmıştır.Endocervikal Chlamydia trachomatis infection was determined pregnant women who had early travail using the EIA (Chlamyfast) test. The control group consisted of 30 pregnants who were not in early travail. Prevalence of Chlamydia infection was 13.3 % in pregnant women in the early travail and 13.3 % in the control group. As the result indicates, there Was no difference between these two groups for endocervical Chlamydia positivity. The effect of C. trachomatis infection on the early travail was discussed

Anti-erosive effects of fluoride and phytosphingosine: an in vitro study

A selection of commercially available products containing stannous fluoride (SnF2)/sodium fluoride (NaF), SnF2/amorphous calcium phosphate (ACP), SnF2/NaF/ACP, tin (Sn)/fluorine (F)/chitosan were compared with phytosphingosine (PHS) with respect to their anti-erosive properties in vitro. One-hundred and twenty bovine enamel specimens were immersed in the respective product slurries for 2 min, twice daily. The formulations were diluted with either remineralization solution or artificial saliva. After each treatment, an erosive challenge was performed for 10 min, twice daily, using citric acid, pH 3.4. The specimens were stored in remineralization solution or artificial saliva until the next treatment-erosion challenge. After 10 d, tissue loss was determined using profilometry. Enamel softening was determined through surface microhardness measurements. Tissue-loss values (measured in μm and expressed as mean ± SD) for PHS, SnF2/NaF, SnF2/ACP, SnF2/ACP/NaF, and Sn/F/chitosan treatment groups and for the negative-control group, were, respectively, 35.6 ± 2.8, 15.8 ± 1.8, 22.1 ± 2.0, 22.9 ± 1.8, 16.2 ± 1.2, and 51.2 ± 4.4 in the presence of remineralization solution and 31.7 ± 3.3, 15.6 ± 2.9, 16.5 ± 2.7, 16.8 ± 2.1, 13.1 ± 3.0, and 50.7 ± 2.8 in the presence of artificial saliva. There were no significant differences in surface microhardness measurements between the treatment groups. In conclusion, PHS resulted in a significant reduction of tissue loss compared with the negative control, but in comparison, the toothpastes containing Sn2+ and F− ions were significantly more effective compared with PHS