Ruqyah and Its Use among Patients with Cancer

Makale (Review)WOS:000968252800001In this article, we reviewed ruqyah from past to present and its use among patients with cancer to attract attention to the importance of ruqyah. Ruqyah, one of the mind–body interventions among complementary and alternative medicine therapies, refers to the healing method based on the Quran and hadith through the recitation of the Quran, seeking of refuge, remembrance, and dua (supplication) that is used as a means of treating sickness and other problems, by reading ayats of the Quran, the names and attributes of Allah, or by using the duas in Arabic or in an understandable language. Ruqyah is frequently used in patients with cancer in combination with medical treatment, and many patients benefit from ruqyah practices. It is usually used to improve emotional and physical well-being, relax, cope with the disease, strengthen the immune system, increase vitality, decrease pain and stress, treat disease, accelerate the healing process, increase the duration of life, improve sleep quality, reduce side effects associated with treatment, and to be self-sufficient. Ruqyah is a complementary method for modern cancer treatment. It is not an alternative to chemotherapy and cannot directly replace medical treatment. Patients can perform ruqyah by themselves without applying to Muslim faith healers or spiritual healing centers. It can be by everyone regardless of their religion and belief. Although ruqyah has been successfully used in various social, mental, spiritual, and physical disorders for over 1,440 years, there are limited randomized controlled trials about its use in patients with cancer due to lack of cooperation between health professionals and Muslim faith healers applying ruqyah. Therefore, we suggest that health professionals develop joint projects and studies with Muslim faith healers and Islamic religion professionals on this subject. Finally, we strongly believe that ruqyah must be integrated into mainstream modern medicine as in the “Malaysia model” in both developing and developed countries

Yenidoğanda distal renal tübüler asidozisli Joubert Sendromu

Joubert Sendromu JS beyin sapı ve serebellar malformasyonlarla karakterize santral sinir sisteminin nadir gelişimsel bir bozuk- luğudur. Göz örneğin, retinal displazi gibi , okulomotor, kas-iskelet ve böbrek örneğin, kistik displazi, nefronofitizis gibi diğer sistemik bozukluklarla ilişkili olabilir. Biz burada distal renal tübüler asidozis ile birlikte olan JS bir olguyu bildiğimiz kadarı ile tıp literatüründe ilk olması nedeni ile sundu

A congenital cranial dysinnervation disorder: Möbius' syndrome

Moebius sendromu, diğer adıyla Moebius sekansı, doğuştan yüz ve göz sinirlerinde felç ile belirgin, ilerleyici olmayan bir kraniyal disinnervasyon bozukluğudur. Emmede zayıflık ve yüz felci nedeniyle izlenen, in vitro dölleme ile oluşan gebelik sonucu doğan, beş günlük kız hastaya iki taraflı pitoz ve dışa bakış kısıtlılığı, dilde sola kayma, dismorfik yüz görünümü, sol el parmak ve tırnaklarında hipoplazi bulguları ile birlikte Moebius sendromu tanısı konuldu. Bu sendroma üç, dört, beş, dokuz, 10 ve 12 gibi ek kraniyal sinir tutulumu, kol ve bacak gelişim anomalileri de eşlik edebilir. Etiolojide bir çok etmen öne sürülmekle beraber yardımcı üreme tekniklerine bağlı nadir olgular bildirilmiştir. Hastalarda beslenme güçlüğü ve aspirasyon sorunları süt çocukluğu döneminde karşılaşılan başlıca sorunlardır. Yüz felci ile doğan yenidoğan diğer kraniyal sinirler bakımından da ayrıntılı muayene edilmeli, ayırıcı tanıda Moebius sendromu ile birlikte diğer kraniyal disinnervasyon bozuklukları göz önünde bulundurulmalıdır.Möbius' syndrome, also known as Möbius' sequence, is a nonprogressive cranial dysinnervation disorder characterized by congenital facial and abducens nerve paralysis. Here, we report a 5-day-old girl who was conceived after in vitro fertilization with poor suck and facial paralysis. She had bilaterally ptosis and lateral gaze limitation, left-sided deviation of the tongue, dysmorphic face, hypoplastic fingers and finger nails on the left hand, and was diagnosed as having Möbius' syndrome. Involvement of other cranial nerves such as three, four, five, nine, 9 and 12, and limb malformations may accompany this syndrome. However, several factors have been proposed for the etiology, some rare cases have also been reported with artificial reproductive technologies. Feeding difficulties and aspiration are the main problems encountered in infancy. The other cranial nerves should be examined further in newborns who present with congenital facial palsy, and other cranial dysinnervation disorders should be considered in the differential diagnosis

Identification of SLC22A5 Gene Mutation in a Family with Carnitine Uptake Defect

Primary systemic carnitine deficiency is caused by homozygous or compound heterozygous mutation in the SLC22A5 gene on chromosome 5q31. The most common presentations are in infancy and early childhood with either metabolic decompensation or cardiac and myopathic manifestations. We report a case of 9-year-old boy with dysmorphic appearance and hypertrophic cardiomyopathy. Tandem MS spectrometry analysis was compatible with carnitine uptake defect (CUD). His sister had died due to sudden infant death at 19 months. His second 4-year-old sister’s echocardiographic examination revealed hypertrophic cardiomyopathy, also suffering from easy fatigability. Her tandem MS spectrometry analyses resulted in CUD. We sequenced all the exons of the SLC22A5 gene encoding the high affinity carnitine transporter OCTN2 in the DNA. And one new mutation (c.1427T>G → p.Leu476Arg) was found in the boy and his sister in homozygous form, leading to the synthesis of an altered protein which causes CUD. The parent’s molecular diagnosis supported the carrier status. In order to explore the genetic background of the patient’s dysmorphic appearance, an array-CGH analysis was performed that revealed nine copy number variations only. Here we report a novel SLC22A5 mutation with the novel hallmark of its association with dysmorphologic feature

Poor prognosis in paediatric haemorrhagic stroke

MakaleWOS:000936965000001PubMed ID: 36661106Stroke, increasingly recognised in children in recent years, is an important cause of long-term morbidity and disability. A wide range of conditions associated with paediatric stroke has been identified, which differ significantly from those in adults. Paediatric stroke can also present with a variety of symptoms and signs, both specific and non-specific [1, 2]. Paediatric haemorrhagic stroke (HS) is a rare but severe condition, with lifelong multifaceted adverse functional, psychosocial, and economic consequences [3]. In this study, we have evaluated the clinical, laboratory and neuroimaging findings in children with HS in order to draw attention to the high morbidity and mortality rates of paediatric HS. (...

Salvation of the Prophet Yunus (alayhi as-salam), swallowed by the big fish: A message for today's physicians

Makale (Early Access)WOS:000906908600001..