STUDENTS' OPINIONS REGARDING STRATEGIC MANAGEMENT COURSE’S INSTRUCTED IN THE GRADUATE PROGRAMS LEVEL OF GAINING QUALIFIED EMPLOYEE TO BUSINESS: A STUDY AT GAZI UNIVERSITY

At the point of monitoring developments taking place in the internal and external environmental conditions of the businesses, gaining the necessary skills is critical. To gain these skills, conscious and visionary individuals are given strategic management course in the universities at the associate degree, undergraduate, graduate and doctor's degree. In this study, students’ opinions regarding the level of strategic management course’s gaining to business with qualified employee were given. To serve this purpose, a research was made on students in Gazi University Social Sciences Institute, registered in 2015-2016 fall semester master’s and doctoral level and taking a strategic management course. Independent Sample T-Test using for comparison and a parametric method analysis was applied to data obtained.As a result of the study, it is observed that students educated in master's and doctoral level expressed their opinions concerning the strategic management course as an important tool to function in providing qualified employee to business in the middle level. As a result of analysis, it is observed that gaining qualified employee to business in a strategic management course is the level of 3, 32 in graduate students and 2, 63 in doctoral students

Structural Phase Transformation, Intermediate States and Electronic Properties of PbTe Under High Pressure

In this work, density functional theory calculations in the framework of local density approximation (LDA) are performed using the Siesta software package in order to theoretically predict the phase transition mechanism and electronic properties of lead telluride (PbTe) under high hydrostatic pressure. PbTe undergoes a structural phase transformation from the cubic NaCl-type structure (B1) belongs to Fm3m space group to another cubic CsCl-type structure (B2) belongs to Pm3m space group with the influence of external pressure through the simulations. According to simulation results, we suggest a phase transition mechanism having four intermediate states with space groups of P 1; C2=m; R3m and Cmmm

Evaluation of the results of the use of two different anticoagulants in COVID-19 patients who were followed-up and treated in the intensive care unit

Introduction: The risk of thromboembolism increases due to tendency to coagulopathy, excessive inflammation, hypoxia, and immobility in patients who are treated of COVID-19 in Intensive Care Units (ICU). Therefore, thromboembolism prophylaxis (anticoagulant therapy) is recommended. There is no clear recommendation in the literature regarding the dose and duration of anticoagulant therapy. In this study, we evaluate of two different anticoagulant administrations in terms of prognosis and mortality in COVID-19 patients who were followed up and treated in the ICU. Methods: After the approval of the Ethics Committee, the study was carried out by retrospectively in ICU affiliated to three different centers. The patients were divided into two groups as those using anticoagulant at a prophylactic dose (Group 1) and treatment dose (Group 2). Various parameters of the patients were evaluated. Results: Of the 91 patients included in the study, 61.5% received prophylactic and 38.5% therapeutic anticoagulants. The rate of male patients 73.9% was found to be significantly higher in the mortal group (p=0.014). About 75.9% of the patients who received mechanical ventilation treatment and 13.59% of the patients who were not applied died (p<0.001). Mortality was higher in the group using prophylactic anticoagulants (58.39% vs. 37.1% p;0.043). Patients using prophylactic doses of anticoagulants had 2.42 times more mortality (Odds Ratio=2.42). Hb levels were found to be lower (p=0.017) and prothrombin time and partial prothrombine time values were long (p=0.048 and 0.038, respectively) in patients who received anticoagulants at the treatment dose. Discussion and Conclusion: Despite the increased tendency for thrombosis in COVID-19, there is no clear preventive or protective treatment. Hence, if there is no contraindicated situation, we believe that anticoagulants can be used safely at the treatment dose to avoid possible thromboembolic complications and reduce the risk of mortality. There is a need for largescale studies on dose selection in terms of prophylaxis

Effects of obesity on elective spinal surgery

Background: Obesity (Body Mass Index > 30 kg/m2) is currently a public health problem with increasing incidence. Obesity increases the challenges and complications of surgery in all surgical branches. In this study, we aimed to evaluate the intraoperative and perioperative complications of obesity encountered in spinal surgery.Materials and Methods: All patients undergoing elective spinal surgery in one orthopedic surgery practice between 2017 and 2018 were included in this study. Patient demographics, body mass index (BMI), preoperative hemoglobin and hematocrit values, volume of blood transfused, incision lengths, number of surgical levels, operational time, and amount of bleeding were retrospectively identified. Patients were divided into two groups according to BMI levels (Group A, 30 kg/m2), and statistical analyses were performed using the Student’s t and Mann-Whitney U tests.Results: Seventy-seven patients with a mean age of 57.8 years (range, 19–72) were included in this study. Their mean BMI was 29.3 kg/m2 (19.9–39 kg/m2). The mean BMI of Group A was 25.7 kg/m2 and that of Group B was 34.6 kg/m2. The amount of bleeding, number of surgical levels, and skin-incision length were statistically significantly different between the two groups. The mean values of all of these parameters were higher in Group B.Conclusion: Although numerous factors play roles in operational success, we believe that identifying obesity in a patient is important for pre- and postoperative surgical preparation by the operation team

The impact of hybrid capture-based comprehensive genomic profiling on treatment strategies in patients with solid tumors

Objective: The development of bioinformatics and comprehensive genomic profiling (CGP) has provided insights into the ap-plicability and functionality of the genomic alterations (GA). In this study, we evaluated the impact of CGP on the treatment plan and outcomes in a significant number of patients. Material and Methods: We carried out a retrospective case-control study on 164 adult patients with advanced solid tumors from 15 oncology centers in Türkiye. Results: In all cases, CGP was performed within 23.8 [standard deviation (SD)±32.1] months of initial diagnosis. Non-small cell lung carcinoma, breast cancer, unknown primary carcinoma, colorectal carcinoma, and sarcoma were among the most common tumor types, accounting for 61.5% of all cases. CGP was performed immediately after the diagnosis of advanced cancer in 13 patients (7.9%). In 158 patients (96.4%), at least one GA was found as per the CGP report. Also, in the reports, the average tumor mutational burden (TMB) and GAs were 7.3 (SD±8.7) mut/Mb and 3.5 (SD±2.0), respectively. According to CGP reports, 58 patients had 79 evidence-based drug suggestions for their particular tumor type, whereas 97 patients had 153 evidence-based drug suggestions for another tumor type. After the primary oncologist interpreted the CGP reports, significant changes were made to the treatment of 35 (21.3%) patients. Conclusion: We strongly believe that in the future, high-TMB or other tumor-agnostic biomarkers will become much more afford-able, and CGP will serve as one of the major decision-making tools for the treatment of patients along with pathological, radiological or lab-oratory tests

Omentum adiposity is linked with resistin gene expression

Background: This study demonstrated site-specific adipose tissue resistin gene expression differences in individuals with and without type 2 diabetes mellitus. The relationship between conventional drug therapy and adipose tissue resistin gene expression was also determined. Paired omental and subcutaneous adipose tissues were excised during elective surgery from morbidly obese and obese patients. Methods: Resistin mRNA expressions were determined by qPCR. All tissue sections also were also analyzed for their resistin and CD68 protein expressions by immunohistochemistry. Results: No significant difference for omental and subcutaneous adipose tissue resistin mRNA expression levels were found among morbidly obese and obese study groups. The omental adipocytes resistin mRNA expressions increased with macrophage number both in the omental and subcutaneus fat. Resistin mRNA expressions of the omental and subcutaneous fat were in positive correlation. As the omental adipocytes radius decreased, the macrophage number increased in subcutaneous fat. In the omentum the adipocytes diameter and areas increased, in correlation with macrophage number. The antidiabetic drug use was found to increase adipocyte size both in the omentum and subcutaneous fat. Conclusions: The higher resistin gene expression in the omental fat may induce the increase in size and number of adipocytes, thus leading to elavation in omental fat mass

Parental psychological distress associated with COVID-19 outbreak: A large-scale multicenter survey from Turkey

Aims: Pandemics can cause substantial psychological distress; however, we do not know the impact of the COVID-19 related lockdown and mental health burden on the parents of school age children. We aimed to comparatively examine the COVID-19 related the stress and psychological burden of the parents with different occupational, locational, and mental health status related backgrounds. Methods: A large-scale multicenter online survey was completed by the parents (n = 3,278) of children aged 6 to 18 years, parents with different occupational (health care workers—HCW [18.2%] vs. others), geographical (İstanbul [38.2%] vs. others), and psychiatric (child with a mental disorder [37.8%]) backgrounds. Results: Multivariable logistic regression analysis showed that being a HCW parent (odds ratio 1.79, p <.001), a mother (odds ratio 1.67, p <.001), and a younger parent (odds ratio 0.98, p =.012); living with an adult with a chronic physical illness (odds ratio 1.38, p <.001), having an acquaintance diagnosed with COVID-19 (odds ratio 1.22, p =.043), positive psychiatric history (odds ratio 1.29, p <.001), and living with a child with moderate or high emotional distress (odds ratio 1.29, p <.001; vs. odds ratio 2.61, p <.001) were independently associated with significant parental distress. Conclusions: Parents report significant psychological distress associated with COVID-19 pandemic and further research is needed to investigate its wider impact including on the whole family unit. © The Author(s) 2020

A new autogenous graft choice in pelvic reconstructions: free vascularized rib (a case report)

Primary or secondary bone tumours are not uncommon in pelvic girdle. In some cases, after radical resection, there is a big bony defect where the prosthesis is not applicable; arthrodesis is the only choice for good functional results. In this instance, the major problem is to achieve the fusion. In this case report, we focused on easy harvesting and minimal time consumption with free vascularized rib graft to achieve the fusion between the resected segments. Two year follow up showed fusion with good functional result

Kyphoplasty for pregnancy-associated osteoporotic vertebral fractures

We report a case of pregnancy-associated osteoporotic vertebral fracture treated by kyphoplasty. This case is important for being the first case of postpregnancy osteoporotic vertebral fracture treated with kyphoplasty. Although kyphoplasty is a very successful procedure in short-term pain relief for osteoporotic vertebral fractures, there is a critical need for randomized controlled trials demonstrating short-term complications of kyphoplasty including new vertebral fractures

Sağlık Kurumlarındaki Yöneticilerin Stratejik Yönetim Araçları Kullanım Görüşleri

Sağlık yönetimi uygulamalarında stratejik yönetim araçlarından faydalanılması sağlık yöneticilerine daha özellikli yönlendirme ve değerlendirmeler yapabilme imkânını vermektedir. Çalışma, Orta Karadeniz Bölgesinde yer alan iller ve bu illere bağlı ilçelerde hizmet veren kamu ve özel hastanelerde çalışan yöneticilerin stratejik yönetim araçları kullanımına ilişkin bakış açılarını ortaya koymak amacıyla gerçekleştirilmiştir. Bu amaçla “stratejik yönetim araçları” ve bu araçlara bakış açılarını ortaya koyan önermelerin yer aldığı “Stratejik Yönetim Araçları Kullanımı Adına Görüş Anketi”nden yararlanılmıştır. Katılımcıların stratejik yönetim araçları kullanımına yönelik bakış açılarını ortaya koyan ifadelerin güvenirliğini belirlemek amacıyla Cronbach Alpha iç tutarlılık katsayısı değeri incelenmiş ve bu değer 0.91 olarak tespit edilmiştir. Bu doğrultuda, Orta Karadeniz Bölgesinde yer alan iller ve bu illere bağlı ilçelerde faaliyette bulunan hastanelerde (kamu-özel) yönetici olarak çalışan toplam 313 kişi üzerinde anket uygulanmıştır. Araştırma sonucunda katılımcıların stratejik yönetim araçları kullanımına ilişkin bakış açılarını ortaya koyan ifadelere yüksek düzeyli (Ort.=3.67) bir katılım sağladıkları görülmüştür. Anket uygulaması sonucu elde edilen verilerin çözümlenmesinde, T-Testi ve Tek Yönlü Varyans (ANOVA) Analizi testi, Post Hoc testlerinden Hochberg’s GT2 testi kullanılmıştır