17 research outputs found

    Nivel de dificultad cognitiva y grado de autenticidad de los problemas de matemáticas en el primer ciclo de Educación Primaria relacionado con los resultados del TIMSS

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    Trabajo Fin de Grado-Universidad de Salamanca, 2014[ES]Se pretende analizar los problemas de matemáticas en el primer ciclo de Educación Primaria desde dos vertientes: por un lado se analizará la dificultad cognitiva de los problemas de matemáticas y, por otro lado , se estudiará su grado de autenticidad. Para tal propósito, se tendrán en cuenta estudios previos.[EN]This paper analyzes the problems of mathematics in the first cycle of primary education from two aspects: first cognitive difficulty of the math problems will be analyzed and, on the other hand Their degree of authenticity will be considered. For that purpose, they shall take into account previous studies

    Aplicación de la teledetección a la inventariación de viñedo en la zona de Denominación de Origen Bierzo

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    La entrada en vigor de la nueva reglamentación sobre la Organización Común de Mercado Vitivinícola, exige inventariar con urgencia el potencial vitícola, en el ámbito regional. En esta ponencia se pretende evaluar la utilidad de la teledetección en el seguimiento e inventariación del cultivo de la vid y su aplicación a la comarca del Bierzo (León). Los resultados obtenidos demuestran la utilidad de la teledetección para evaluar el potencial vitícola aunque deben mejorarse utilizando imágenes de alta resolución espacia

    Multiparametric Study of Antioxidant Effect on Ram Sperm Cryopreservation—From Field Trials to Research Bench

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    The optimization of sperm cryopreservation protocols in ram is a feasible tool to reinforce artificial insemination technologies considering the desirable application of sperm by vaginal/cervical or transcervical deposition. Cryopreservation provokes different types of damage on spermatozoa and many of these detrimental effects are triggered by redox deregulation. For this reason, the antioxidant supplementation in sperm cryopreservation protocols to decrease reactive oxygen species (ROS) levels and to equilibrate redox status has been widely employed in different species. Despite this, more fertility trials are necessary to provide the definitive tool to ensure the antioxidant effectiveness on sperm quality. For this reason, in this work, we performed a multiparametric analysis of some previously tested antioxidants (crocin, GSH and Trolox) on ram sperm cryopreservation from field trials to sperm quality analyses focused on new strategies to measure redox balance. Attending to fertility trial, Trolox supplementation registered an improvement concerning to fertility (when we considered high fertility males) and multiple lambing frequency and other complementary and descriptive data related to lambing performance such as prolificacy and fecundity. This positive effect was more evident in multiple lambing frequency when we considered low fertility males than in global male analysis. In vitro analyses of sperm quality confirmed in vivo trials registering a positive effect on sperm viability and redox balance. In this study, we provided the definitive evidence that the role of trolox on redox balance maintenance has a direct effect on fertility parameters, such as prolificacy. The effectiveness of antioxidant treatments was tested, for the first time in ovine species, using an integrative and multiparametric approach combining in vivo and in vitro analyses and novel approaches, such as RedoxSYS. These types of strategies should be applied to improve sperm conservation methods and optimize AI technologies upgrading the correlation between in vitro and in vivo analyses.SIFunding: This work was financially supported by the Junta de Castilla y León (LE253P18) and MINECO (AGL2017-83098-R) project and the University of León.Acknowledgments: The authors acknowledge the JCyL-LE253P18 research contract and ORDEN EDU/556/2019 fellowship (Junta Castilla y León), FPU17/04142 (MCIU) and PRE2018-086400 (MEC) fellowships, Carlos Palacio Riocerezo, the ITRA-ULE technicians (Ainoa Jordán, Pedro de Vega and Cecilia Pérez), ANCHE and the staff from Ovigén

    Healthcare workers hospitalized due to COVID-19 have no higher risk of death than general population. Data from the Spanish SEMI-COVID-19 Registry

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    Aim To determine whether healthcare workers (HCW) hospitalized in Spain due to COVID-19 have a worse prognosis than non-healthcare workers (NHCW). Methods Observational cohort study based on the SEMI-COVID-19 Registry, a nationwide registry that collects sociodemographic, clinical, laboratory, and treatment data on patients hospitalised with COVID-19 in Spain. Patients aged 20-65 years were selected. A multivariate logistic regression model was performed to identify factors associated with mortality. Results As of 22 May 2020, 4393 patients were included, of whom 419 (9.5%) were HCW. Median (interquartile range) age of HCW was 52 (15) years and 62.4% were women. Prevalence of comorbidities and severe radiological findings upon admission were less frequent in HCW. There were no difference in need of respiratory support and admission to intensive care unit, but occurrence of sepsis and in-hospital mortality was lower in HCW (1.7% vs. 3.9%; p = 0.024 and 0.7% vs. 4.8%; p<0.001 respectively). Age, male sex and comorbidity, were independently associated with higher in-hospital mortality and healthcare working with lower mortality (OR 0.211, 95%CI 0.067-0.667, p = 0.008). 30-days survival was higher in HCW (0.968 vs. 0.851 p<0.001). Conclusions Hospitalized COVID-19 HCW had fewer comorbidities and a better prognosis than NHCW. Our results suggest that professional exposure to COVID-19 in HCW does not carry more clinical severity nor mortality

    Nivel de dificultad cognitiva y grado de autenticidad de los problemas de matemáticas en el primer ciclo de Educación Primaria relacionado con los resultados del TIMSS

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    Resumen en español e inglésResumen basado en el de la publicaciónSe analizan los problemas de matemáticas en el primer ciclo de Educación Primaria desde dos vertientes: por un lado se analizará la dificultad cognitiva de los problemas de matemáticas y, por otro lado, se estudiará su grado de autenticidad. Este análisis se realizara con el objetivo de conocer en qué manera influye el grado de autenticidad y la dificultad cognitiva de los problemas de matemáticas en la enseñanza y resolución de problemas.Castilla y LeónES

    Comparing the Effect of Different Antibiotics in Frozen-Thawed Ram Sperm: Is It Possible to Avoid Their Addition?

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    [EN] It is crucial to perform a deep study about the most extensively used antibiotics in sperm extenders.Most of the protocols and concentrations used in ramare direct extrapolations from other species. It is important to establish species-specific antibiotic treatments to optimize their use and if it is possible to reduce the quantity. Previews studies have assessed some aspects of sperm quality in vitro, but this study aimed to go further and assess the effect of three different antibiotic treatments, which are the most extensively used, not only in sperm quality or assessing the inhibitory effect on bacterial growth but also assessing these important parameters of productivity such as fertility, prolificacy, fecundity, and sex-ratio during a freeze-thaw process. Gentamicyn (G) treatment showed the worst results, not only concerning sperm quality but also in the reproductive trials exhibiting a toxical effect at the experiment concentration, and being the most powerful inhibiting bacterial growth. For its part, Lincomicyn-spectinomycin (LS) showed similar results inhibiting bacterial growth but it did not show a detrimental effect either in sperm quality or in reproductive parameters. Penicillin-streptomycin (PS) showed good results in the sperm quality and in the reproductive in vivo trials, but it showed a very poor effect inhibiting bacterial growth probably due to some kind of antibiotic resistance. According to our results, there is not a significant positive relationship between the higher bacterial inhibitory activity of LS and PS samples, and the sperm quality respect Control samples (without antibiotics). In the case of G, which exhibited the most effective as antibacterial, we observed a toxic effect on sperm quality that could be translated on productivity parameters. Our results suggest that the bacterial contamination control in frozen-thawed semenmay be possible without the use of antibiotics, although the effects of longer periods of cooling storage and different temperatures of storage need to be further investigated for animal semen. At this point, a reflection about a drastic reduction in the use of antibiotic treatments in sperm cryopreservation is mandatory, since freezing conditions could keep sperm doses contamination within the levels recommended by regulatory health agencies.SIThe authors acknowledge the JCyL-LE253P18 research contract and ORDEN EDU/556/2019 fellowship (Junta Castilla y León), FPU17/04142 (MCIU) and PRE2018-086400 (MEC) fellowships, the ITRA-ULE technicians (Ainoa Jordán, Pedro de Vega and Cecilia Pérez), ANCHE and the staff from Ovigé
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