Pathophysiology, histopathology and therapeutic of SARS-CoV-2

The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH

Antitrust and Intellectual Property: Unresolved Issues at the Heart of the New Economy

The New Economy differs in degree rather than kind from the old economy. Part II of this discussion examines the key differences that define the New Economy. Part Ill turns to several implications of those differences as they pertain to antitrust enforcement. I argue that the differences do not justify sweeping generalizations that antitrust enforcement has no place in the New Economy, but do require antitrust enforcement to make adjustments and exercise sensitivity towards intellectual property issues on a case-by-case basis. The goal of a coherent overall competition policy, in deciding both what conduct to enforce against and what remedies to require, should be to achieve an appropriate balance between the complementary legal regimes of intellectual property and antitrust. Part IV examines several examples of recent antitrust enforcement decisions involving intellectual property. Without addressing the ultimate merits of individual decisions, I find that antitrust enforcement has generally evolved in recent years in a way that pays heed to the distinctive characteristics of the New Economy. These decisions demonstrate a concerted attempt to give reasonable, fact-specific consideration to both incentives and opportunities to innovate. Finally, to supplement the preceding review of substantive issues, Part V examines the institutional challenges posed to antitrust enforcement by the New Economy

Inter-Domain Integration of Services and Service Management

The evolution of the global telecommunications industry into an open services market presents developers of telecommunication service and management systems with many new challenges. Increased competition, complex service provision chains and integrated service offerings require effective techniques for the rapid integration of service and management systems over multiple organisational domains. These integration issues have been examined in the ACTS project Prospect by developing a working set of integrated, managed telecommunications services for a user trial. This paper presents the initial results of this work detailing the technologies and standards used, the architectural approach taken and the application of this approach to specific services

Multi-camera complexity assessment system for assembly line work stations

In the last couple of years, the market demands an increasing number of product variants. This leads to an inevitable rise of the complexity in manufacturing systems. A model to quantify the complexity in a workstation has been developed, but part of the analysis is done manually. Thereto, this paper presents the results of an industrial proof-of-concept in which the possibility of automating the complexity analysis using multi camera video images, was tested

Power Systems Monitoring and Control using Telecom Network Management Standards

Historically, different solutions have been developed for power systems control and telecommunications network management environments. The former was characterized by proprietary solutions, while the latter has been involved for years in a strong standardization process guided by criteria of openness. Today, power systems control standardization is in progress, but it is at an early stage compared to the telecommunications management area, especially in terms of information modeling. Today, control equipment tends to exhibit more computational power, and communication lines have increased their performance. These trends hint at some conceptual convergence between power systems and telecommunications networks from a management perspective. This convergence leads us to suggest the application of well-established telecommunications management standards for power systems control. This paper shows that this is a real medium-to-long term possibility

Strategic marketing, production, and distribution planning of an integrated manufacturing system

Production Scheduling;Distribution;CIM;production

Experiences in Multi-domain Management Service Development

The developers of management systems and the management services that operate over them will be faced with increasing complexity as services are developed for the open service market. This paper presents experiences in the development of management services that span several administrative domains and which are therefore representative of the complexities of the open service market. The work described involved the development of TMN based management systems that provided management services in support of multimedia teleservices operating over broadband networks

Applications and benefits of digital human models to improve the design of workcells in car’s manufacturing plants according to international standards

During last years, the car’s manufacturing process has deeply changed because of several factors affected the automotive global scenario. As a consequence, design methodologies of the plant’s workcells have changed. In particular, ergonomics for manufacturing system has become a key factor to improve product’s quality, safety and work organization. In this paper, the authors show the approach used in Fiat Group Automobiles (FGA) based on simulation tools to analyse ergonomic aspects of work-cells already in design phase. Simulation tools allow a deep postural analysis that is one of the main criticism in the design phase. The principles of Digital Human Modeling have been used to develop an easy internal virtual manikin, the Human Model. The tool, based on ISO standards and on a worldwide anthropometric database, allows designers to simulate the most probable postures engaged by operator during work tasks as well as to validate improvements and corrective actions

The technology base for agile manufacturing

The effective use of information is a critical problem faced by manufacturing organizations that must respond quickly to market changes. As product runs become shorter, rapid and efficient development of product manufacturing facilities becomes crucial to commercial success. Effective information utilization is a key element to successfully meeting these requirements. This paper reviews opportunities for developing technical solutions to information utilization problems within a manufacturing enterprise and outlines a research agenda for solving these problems