Towards a lightweight generic computational grid framework for biological research

Background: An increasing number of scientific research projects require access to large-scale computational resources. This is particularly true in the biological field, whether to facilitate the analysis of large high-throughput data sets, or to perform large numbers of complex simulations – a characteristic of the emerging field of systems biology. Results: In this paper we present a lightweight generic framework for combining disparate computational resources at multiple sites (ranging from local computers and clusters to established national Grid services). A detailed guide describing how to set up the framework is available from the following URL: http://igrid-ext.cryst.bbk.ac.uk/portal_guide/. Conclusion: This approach is particularly (but not exclusively) appropriate for large-scale biology projects with multiple collaborators working at different national or international sites. The framework is relatively easy to set up, hides the complexity of Grid middleware from the user, and provides access to resources through a single, uniform interface. It has been developed as part of the European ImmunoGrid project

A component-based middleware framework for configurable and reconfigurable Grid computing

Significant progress has been made in the design and development of Grid middleware which, in its present form, is founded on Web services technologies. However, we argue that present-day Grid middleware is severely limited in supporting projected next-generation applications which will involve pervasive and heterogeneous networked infrastructures, and advanced services such as collaborative distributed visualization. In this paper we discuss a new Grid middleware framework that features (i) support for advanced network services based on the novel concept of pluggable overlay networks, (ii) an architectural framework for constructing bespoke Grid middleware platforms in terms of 'middleware domains' such as extensible interaction types and resource discovery. We believe that such features will become increasingly essential with the emergence of next-generation e-Science applications. Copyright (c) 2005 John Wiley & Sons, Ltd

A Taxonomy of Workflow Management Systems for Grid Computing

With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources. Such application scenarios require means for composing and executing complex workflows. Therefore, many efforts have been made towards the development of workflow management systems for Grid computing. In this paper, we propose a taxonomy that characterizes and classifies various approaches for building and executing workflows on Grids. We also survey several representative Grid workflow systems developed by various projects world-wide to demonstrate the comprehensiveness of the taxonomy. The taxonomy not only highlights the design and engineering similarities and differences of state-of-the-art in Grid workflow systems, but also identifies the areas that need further research.Comment: 29 pages, 15 figure

Development of Grid e-Infrastructure in South-Eastern Europe

Over the period of 6 years and three phases, the SEE-GRID programme has established a strong regional human network in the area of distributed scientific computing and has set up a powerful regional Grid infrastructure. It attracted a number of user communities and applications from diverse fields from countries throughout the South-Eastern Europe. From the infrastructure point view, the first project phase has established a pilot Grid infrastructure with more than 20 resource centers in 11 countries. During the subsequent two phases of the project, the infrastructure has grown to currently 55 resource centers with more than 6600 CPUs and 750 TBs of disk storage, distributed in 16 participating countries. Inclusion of new resource centers to the existing infrastructure, as well as a support to new user communities, has demanded setup of regionally distributed core services, development of new monitoring and operational tools, and close collaboration of all partner institution in managing such a complex infrastructure. In this paper we give an overview of the development and current status of SEE-GRID regional infrastructure and describe its transition to the NGI-based Grid model in EGI, with the strong SEE regional collaboration.Comment: 22 pages, 12 figures, 4 table

SLA-Oriented Resource Provisioning for Cloud Computing: Challenges, Architecture, and Solutions

Cloud computing systems promise to offer subscription-oriented, enterprise-quality computing services to users worldwide. With the increased demand for delivering services to a large number of users, they need to offer differentiated services to users and meet their quality expectations. Existing resource management systems in data centers are yet to support Service Level Agreement (SLA)-oriented resource allocation, and thus need to be enhanced to realize cloud computing and utility computing. In addition, no work has been done to collectively incorporate customer-driven service management, computational risk management, and autonomic resource management into a market-based resource management system to target the rapidly changing enterprise requirements of Cloud computing. This paper presents vision, challenges, and architectural elements of SLA-oriented resource management. The proposed architecture supports integration of marketbased provisioning policies and virtualisation technologies for flexible allocation of resources to applications. The performance results obtained from our working prototype system shows the feasibility and effectiveness of SLA-based resource provisioning in Clouds.Comment: 10 pages, 7 figures, Conference Keynote Paper: 2011 IEEE International Conference on Cloud and Service Computing (CSC 2011, IEEE Press, USA), Hong Kong, China, December 12-14, 201