Extraction and Detection of Fetal Electrocardiograms from Abdominal Recordings

The non-invasive fetal ECG (NIFECG), derived from abdominal surface electrodes, offers novel diagnostic possibilities for prenatal medicine. Despite its straightforward applicability, NIFECG signals are usually corrupted by many interfering sources. Most significantly, by the maternal ECG (MECG), whose amplitude usually exceeds that of the fetal ECG (FECG) by multiple times. The presence of additional noise sources (e.g. muscular/uterine noise, electrode motion, etc.) further affects the signal-to-noise ratio (SNR) of the FECG. These interfering sources, which typically show a strong non-stationary behavior, render the FECG extraction and fetal QRS (FQRS) detection demanding signal processing tasks. In this thesis, several of the challenges regarding NIFECG signal analysis were addressed. In order to improve NIFECG extraction, the dynamic model of a Kalman filter approach was extended, thus, providing a more adequate representation of the mixture of FECG, MECG, and noise. In addition, aiming at the FECG signal quality assessment, novel metrics were proposed and evaluated. Further, these quality metrics were applied in improving FQRS detection and fetal heart rate estimation based on an innovative evolutionary algorithm and Kalman filtering signal fusion, respectively. The elaborated methods were characterized in depth using both simulated and clinical data, produced throughout this thesis. To stress-test extraction algorithms under ideal circumstances, a comprehensive benchmark protocol was created and contributed to an extensively improved NIFECG simulation toolbox. The developed toolbox and a large simulated dataset were released under an open-source license, allowing researchers to compare results in a reproducible manner. Furthermore, to validate the developed approaches under more realistic and challenging situations, a clinical trial was performed in collaboration with the University Hospital of Leipzig. Aside from serving as a test set for the developed algorithms, the clinical trial enabled an exploratory research. This enables a better understanding about the pathophysiological variables and measurement setup configurations that lead to changes in the abdominal signal's SNR. With such broad scope, this dissertation addresses many of the current aspects of NIFECG analysis and provides future suggestions to establish NIFECG in clinical settings.:Abstract Acknowledgment Contents List of Figures List of Tables List of Abbreviations List of Symbols (1)Introduction 1.1)Background and Motivation 1.2)Aim of this Work 1.3)Dissertation Outline 1.4)Collaborators and Conflicts of Interest (2)Clinical Background 2.1)Physiology 2.1.1)Changes in the maternal circulatory system 2.1.2)Intrauterine structures and feto-maternal connection 2.1.3)Fetal growth and presentation 2.1.4)Fetal circulatory system 2.1.5)Fetal autonomic nervous system 2.1.6)Fetal heart activity and underlying factors 2.2)Pathology 2.2.1)Premature rupture of membrane 2.2.2)Intrauterine growth restriction 2.2.3)Fetal anemia 2.3)Interpretation of Fetal Heart Activity 2.3.1)Summary of clinical studies on FHR/FHRV 2.3.2)Summary of studies on heart conduction 2.4)Chapter Summary (3)Technical State of the Art 3.1)Prenatal Diagnostic and Measuring Technique 3.1.1)Fetal heart monitoring 3.1.2)Related metrics 3.2)Non-Invasive Fetal ECG Acquisition 3.2.1)Overview 3.2.2)Commercial equipment 3.2.3)Electrode configurations 3.2.4)Available NIFECG databases 3.2.5)Validity and usability of the non-invasive fetal ECG 3.3)Non-Invasive Fetal ECG Extraction Methods 3.3.1)Overview on the non-invasive fetal ECG extraction methods 3.3.2)Kalman filtering basics 3.3.3)Nonlinear Kalman filtering 3.3.4)Extended Kalman filter for FECG estimation 3.4)Fetal QRS Detection 3.4.1)Merging multichannel fetal QRS detections 3.4.2)Detection performance 3.5)Fetal Heart Rate Estimation 3.5.1)Preprocessing the fetal heart rate 3.5.2)Fetal heart rate statistics 3.6)Fetal ECG Morphological Analysis 3.7)Problem Description 3.8)Chapter Summary (4)Novel Approaches for Fetal ECG Analysis 4.1)Preliminary Considerations 4.2)Fetal ECG Extraction by means of Kalman Filtering 4.2.1)Optimized Gaussian approximation 4.2.2)Time-varying covariance matrices 4.2.3)Extended Kalman filter with unknown inputs 4.2.4)Filter calibration 4.3)Accurate Fetal QRS and Heart Rate Detection 4.3.1)Multichannel evolutionary QRS correction 4.3.2)Multichannel fetal heart rate estimation using Kalman filters 4.4)Chapter Summary (5)Data Material 5.1)Simulated Data 5.1.1)The FECG Synthetic Generator (FECGSYN) 5.1.2)The FECG Synthetic Database (FECGSYNDB) 5.2)Clinical Data 5.2.1)Clinical NIFECG recording 5.2.2)Scope and limitations of this study 5.2.3)Data annotation: signal quality and fetal amplitude 5.2.4)Data annotation: fetal QRS annotation 5.3)Chapter Summary (6)Results for Data Analysis 6.1)Simulated Data 6.1.1)Fetal QRS detection 6.1.2)Morphological analysis 6.2)Own Clinical Data 6.2.1)FQRS correction using the evolutionary algorithm 6.2.2)FHR correction by means of Kalman filtering (7)Discussion and Prospective 7.1)Data Availability 7.1.1)New measurement protocol 7.2)Signal Quality 7.3)Extraction Methods 7.4)FQRS and FHR Correction Algorithms (8)Conclusion References (A)Appendix A - Signal Quality Annotation (B)Appendix B - Fetal QRS Annotation (C)Appendix C - Data Recording GU

Decaying DC offset current mitigation in phasor estimation applications: A Review

Decaying DC (DDC) offset current mitigation is a vital challenge in phasor current estimation since it causes malfunctioning/maloperation of measurements and protection systems. Due to the inductive nature of electric power systems, the current during fault inception cannot change immediately and it contains a transient oscillation. The oscillatory component acts similar to an exponential DC signal and its characteristics depend on the X/R ratio of the system, fault location, and fault impedance. DDC attenuates accurate phasor estimation, which is pivotal in protection systems. Therefore, the DDC must be eliminated from the fault current (FC) signal. This paper presents an overview of DDC mitigation methods by considering different groups—before the discrete Fourier transform (pre-DFT), after the discrete Fourier transform (post-DFT), the least square-based (LS-based), and other methods. Through a comprehensive review of the existing schemes, the effects of noise, harmonics, multiple DDCs (MDDCs), and off-nominal frequency (ONF) on the accuracy of DDC estimation, were recognized. A detailed discussion (along with some simulation results) are presented to address the main advantages/disadvantages of the past studies. Finally, this paper presents a few suggestions for future researchers, for researchers to investigate more implementable solutions in this field

Development of new fault detection methods for rotating machines (roller bearings)

Abstract Early fault diagnosis of roller bearings is extremely important for rotating machines, especially for high speed, automatic and precise machines. Many research efforts have been focused on fault diagnosis and detection of roller bearings, since they constitute one the most important elements of rotating machinery. In this study a combination method is proposed for early damage detection of roller bearing. Wavelet packet transform (WPT) is applied to the collected data for denoising and the resulting clean data are break-down into some elementary components called Intrinsic mode functions (IMFs) using Ensemble empirical mode decomposition (EEMD) method. The normalized energy of three first IMFs are used as input for Support vector machine (SVM) to recognize whether signals are sorting out from healthy or faulty bearings. Then, since there is no robust guide to determine amplitude of added noise in EEMD technique, a new Performance improved EEMD (PIEEMD) is proposed to determine the appropriate value of added noise. A novel feature extraction method is also proposed for detecting small size defect using Teager-Kaiser energy operator (TKEO). TKEO is applied to IMFs obtained to create new feature vectors as input data for one-class SVM. The results of applying the method to acceleration signals collected from an experimental bearing test rig demonstrated that the method can be successfully used for early damage detection of roller bearings. Most of the diagnostic methods that have been developed up to now can be applied for the case stationary working conditions only (constant speed and load). However, bearings often work at time-varying conditions such as wind turbine supporting bearings, mining excavator bearings, vehicles, robots and all processes with run-up and run-down transients. Damage identification for bearings working under non-stationary operating conditions, especially for early/small defects, requires the use of appropriate techniques, which are generally different from those used for the case of stationary conditions, in order to extract fault-sensitive features which are at the same time insensitive to operational condition variations. Some methods have been proposed for damage detection of bearings working under time-varying speed conditions. However, their application might increase the instrumentation cost because of providing a phase reference signal. Furthermore, some methods such as order tracking methods still can be applied when the speed variation is limited. In this study, a novel combined method based on cointegration is proposed for the development of fault features which are sensitive to the presence of defects while in the same time they are insensitive to changes in the operational conditions. It does not require any additional measurements and can identify defects even for considerable speed variations. The signals acquired during run-up condition are decomposed into IMFs using the performance improved EEMD method. Then, the cointegration method is applied to the intrinsic mode functions to extract stationary residuals. The feature vectors are created by applying the Teager-Kaiser energy operator to the obtained stationary residuals. Finally, the feature vectors of the healthy bearing signals are utilized to construct a separating hyperplane using one-class support vector machine. Eventually the proposed method was applied to vibration signals measured on an experimental bearing test rig. The results verified that the method can successfully distinguish between healthy and faulty bearings even if the shaft speed changes dramatically

Wavelet Theory

The wavelet is a powerful mathematical tool that plays an important role in science and technology. This book looks at some of the most creative and popular applications of wavelets including biomedical signal processing, image processing, communication signal processing, Internet of Things (IoT), acoustical signal processing, financial market data analysis, energy and power management, and COVID-19 pandemic measurements and calculations. The editor’s personal interest is the application of wavelet transform to identify time domain changes on signals and corresponding frequency components and in improving power amplifier behavior

Detecting patterns in Time Series Data with applications in Official Statistics

This thesis examines the issue of detecting components or features within time series data in automatic procedures. We begin by introducing the concept of Wavelets and briefly show their usage as a tool for detection. This leads to our first contribution which is a novel method using wavelets for identifying correlation structures in time series data which are often ambiguous with very different contexts. Using the properties of the wavelet transform we show the ability to distinguish between short memory models with changepoints and long memory models. The next two Chapters consider seasonality within data, which is often present in time series used in Offical Statistics. We first describe the historical evolution of identification of seasonality, comparing and contrasting methodology as it has expanded throughout time. Following this, motivated by the increased use of high-frequency time series in Official Statistics and a lack of methods for identifying low-frequency seasonal components within high-frequency data, we present a method for identifying periodicity in a series with the use of a simple wavelet decomposition. Presented with theoretical results and simulations, we show how the seasonality of a series is uniquely represented within a wavelet transform and use this to identify low frequency components which are often overlooked in favour of a trend, with very different interpretations. Finally, beginning with the motivation of forecasting European Area GDP at the current time point, we show the effectiveness of an algorithm which detects the most useful data and structures for a Dynamic Factor Model. We show its effectiveness in reducing forecasting errors but show that under large scale simulation that the recovery of the true structure over two dimensions is a difficult task. All the chapters of this thesis are motivated by, and give applications to, time series from different areas of Official Statistics

Signals and Images in Sea Technologies

Life below water is the 14th Sustainable Development Goal (SDG) envisaged by the United Nations and is aimed at conserving and sustainably using the oceans, seas, and marine resources for sustainable development. It is not difficult to argue that signals and image technologies may play an essential role in achieving the foreseen targets linked to SDG 14. Besides increasing the general knowledge of ocean health by means of data analysis, methodologies based on signal and image processing can be helpful in environmental monitoring, in protecting and restoring ecosystems, in finding new sensor technologies for green routing and eco-friendly ships, in providing tools for implementing best practices for sustainable fishing, as well as in defining frameworks and intelligent systems for enforcing sea law and making the sea a safer and more secure place. Imaging is also a key element for the exploration of the underwater world for various scopes, ranging from the predictive maintenance of sub-sea pipelines and other infrastructure projects, to the discovery, documentation, and protection of sunken cultural heritage. The scope of this Special Issue encompasses investigations into techniques and ICT approaches and, in particular, the study and application of signal- and image-based methods and, in turn, exploration of the advantages of their application in the previously mentioned areas

Harmonic Current Detection And Control Of Active Power Filter Based On Signal Processing

With the advance of social science and technology, the wide use of power equipment and devices has brought a lot of harmonic interference to the power system. These harmonic interference has seriously affected the stability and normal operation of the power system. In order to solve the problem of harmonic pollution in power system, from the point of view of signal processing, active power filter is introduced to detect and process current harmonics. An improved ip-iq detection method based on adaptive LMS-LMF is proposed to achieve high-precision and high-efficiency harmonic current detection. And the command current tracking control is realized by combining space voltage vector and hysteresis contrast control method. The simulation results show that the response time of the improved ip-iq method is 0.05 s, the load current distortion rate is 4.31%, and the harmonic current can be detected quickly and accurately. The power factor of the system is basically kept within the range of 0.95-1, which can quickly adapt to the sudden change of load. It remains stable within 0.01 s of sudden change of load, and has good dynamic response ability. Improved ip-iq detection method based on adaptive LMS-LMF and space voltage vector. Under the comprehensive effect of hysteresis contrast control method, active power filter can effectively track the command current, suppress the harmonic current, and improve the power factor of the system. It has important practical value for improving the power quality of the power grid system

Sensor Signal and Information Processing II

In the current age of information explosion, newly invented technological sensors and software are now tightly integrated with our everyday lives. Many sensor processing algorithms have incorporated some forms of computational intelligence as part of their core framework in problem solving. These algorithms have the capacity to generalize and discover knowledge for themselves and learn new information whenever unseen data are captured. The primary aim of sensor processing is to develop techniques to interpret, understand, and act on information contained in the data. The interest of this book is in developing intelligent signal processing in order to pave the way for smart sensors. This involves mathematical advancement of nonlinear signal processing theory and its applications that extend far beyond traditional techniques. It bridges the boundary between theory and application, developing novel theoretically inspired methodologies targeting both longstanding and emergent signal processing applications. The topic ranges from phishing detection to integration of terrestrial laser scanning, and from fault diagnosis to bio-inspiring filtering. The book will appeal to established practitioners, along with researchers and students in the emerging field of smart sensors processing