Automatic ECG Analysis for Preliminary and Detailed Diagnostics Based on Scale-space Representation

A novel approach of automatic ECG analysis based on scale-scale signal representation is proposed. The approach uses curvature scale-space representation to locate main ECG waveform limits and peaks and may be used to correct results of other ECG analysis techniques or independently. Moreover dynamic matching of ECG CSS representations provides robust preliminary recognition of ECG abnormalities which has been proven by experimental results

A quick search method for audio signals based on a piecewise linear representation of feature trajectories

This paper presents a new method for a quick similarity-based search through long unlabeled audio streams to detect and locate audio clips provided by users. The method involves feature-dimension reduction based on a piecewise linear representation of a sequential feature trajectory extracted from a long audio stream. Two techniques enable us to obtain a piecewise linear representation: the dynamic segmentation of feature trajectories and the segment-based Karhunen-L\'{o}eve (KL) transform. The proposed search method guarantees the same search results as the search method without the proposed feature-dimension reduction method in principle. Experiment results indicate significant improvements in search speed. For example the proposed method reduced the total search time to approximately 1/12 that of previous methods and detected queries in approximately 0.3 seconds from a 200-hour audio database.Comment: 20 pages, to appear in IEEE Transactions on Audio, Speech and Language Processin

DELINEATION OF ECG FEATURE EXTRACTION USING MULTIRESOLUTION ANALYSIS FRAMEWORK

ECG signals have very features time-varying morphology, distinguished as P wave, QRS complex, and T wave. Delineation in ECG signal processing is an important step used to identify critical points that mark the interval and amplitude locations in the features of each wave morphology. The results of ECG signal delineation can be used by clinicians to associate the pattern of delineation point results with morphological classes, besides delineation also produces temporal parameter values of ECG signals. The delineation process includes detecting the onset and offset of QRS complex, P and T waves that represented as pulse width, and also the detection of the peak from each wave feature. The previous study had applied bandpass filters to reduce amplitude of P and T waves, then the signal was passed through non-linear transformations such as derivatives or square to enhance QRS complex. However, the spectrum bandwidth of QRS complex from different patients or same patient may be different, so the previous method was less effective for the morphological variations in ECG signals. This study developed delineation from the ECG feature extraction based on multiresolution analysis with discrete wavelet transform. The mother wavelet used was a quadratic spline function with compact support. Finally, determination of R, T, and P wave peaks were shown by zero crossing of the wavelet transform signals, while the onset and offset were generated from modulus maxima and modulus minima. Results show the proposed method was able to detect QRS complex with sensitivity of 97.05% and precision of 95.92%, T wave detection with sensitivity of 99.79% and precision of 96.46%, P wave detection with sensitivity of 56.69% and precision of 57.78%. The implementation in real time analysis of time-varying ECG morphology will be addressed in the future research

Image compression and energy harvesting for energy constrained sensors

Title from PDF of title page, viewed on June 21, 2013Dissertation advisor: Walter D. Leon-SalasVitaIncludes bibliographic references (pages 176-[187])Thesis (Ph.D.)--School of Computing and Engineering. University of Missouri--Kansas City, 2013The advances in complementary metal-oxide-semiconductor (CMOS) technology have led to the integration of all components of electronic system into a single integrated circuit. Ultra-low power circuit techniques have reduced the power consumption of circuits. Moreover, solar cells with improved efficiency can be integrated on chip to harvest energy from sunlight. As a result of all the above, a new class of miniaturized electronic systems known as self-powered system on a chip has emerged. There is an increasing research interest in the area of self-powered devices which provide cost-effective solutions especially when these devices are used in the areas that changing or replacing batteries is too costly. Therefore, image compression and energy harvesting are studied in this dissertation. The integration of energy harvesting, image compression, and an image sensor on the same chip provides the energy source to charge a battery, reduces the data rate, and improves the performance of wireless image sensors. Integrated circuits of image compression, solar energy harvesting, and image sensors are studied, designed, and analyzed in this work. In this dissertation, a hybrid image sensor that can perform the tasks of sensing and energy harvesting is presented. Photodiodes of hybrid image sensor can be programmed as image sensors or energy harvesting cells. The hybrid image sensor can harvest energy in between frames, in sleep mode, and even when it is taking images. When sensing images and harvesting energy are both needed at the same time, some pixels have to work as sensing pixels, and the others have to work as solar cells. Since some pixels are devoted to harvest energy, the resolution of the image will be reduced. To preserve the resolution or to keep the fair resolution when a lot of energy collection is needed, image reconstruction algorithms and compressive sensing theory provide solutions to achieve a good image quality. On the other hand, when the battery has enough charge, image compression comes into the picture. Multiresolution decomposition image compression provides a way to compress image data in order to reduce the energy need from data transmission. The solution provided in this dissertation not only harvests energy but also saves energy resulting long lasting wireless sensors. The problem was first studied at the system level to identify the best system-level configuration which was then implemented on silicon. As a proof of concept, a 32 x 32 array of hybrid image sensor, a 32 x 32 array of image sensor with multiresolution decomposition compression, and a compressive sensing converter have been designed and fabricated in a standard 0.5 [micrometer] CMOS process. Printed circuit broads also have been designed to test and verify the proposed and fabricated chips. VHDL and Matlab codes were written to generate the proper signals to control, and read out data from chips. Image processing and recovery were carried out in Matlab. DC-DC converters were designed to boost the inherently low voltage output of the photodiodes. The DC-DC converter has also been improved to increase the efficiency of power transformation.Introduction -- Hybrid imager system and circuit design -- Hybrid imager energy harvesting and image acquisition results and discussion -- Detailed description and mathematical analysis for a circuit of energy harvesting using on-chip solar cells -- Multiresolution decomposition for lossless and near-lossless compression -- An incremental [sigma-delta] converter for compressive sensing -- Detailed description of a sigma-delta random demodulator converter architecture for compressive sensing applications -- Conclusion -- Appendix A. Chip pin-out -- Appendix B. Schematics -- Appendix C. Pictures of custom PC

Analysis and resynthesis of polyphonic music

This thesis examines applications of Digital Signal Processing to the analysis, transformation, and resynthesis of musical audio. First I give an overview of the human perception of music. I then examine in detail the requirements for a system that can analyse, transcribe, process, and resynthesise monaural polyphonic music. I then describe and compare the possible hardware and software platforms. After this I describe a prototype hybrid system that attempts to carry out these tasks using a method based on additive synthesis. Next I present results from its application to a variety of musical examples, and critically assess its performance and limitations. I then address these issues in the design of a second system based on Gabor wavelets. I conclude by summarising the research and outlining suggestions for future developments

Strategies for neural networks in ballistocardiography with a view towards hardware implementation

A thesis submitted for the degree of Doctor of Philosophy at the University of LutonThe work described in this thesis is based on the results of a clinical trial conducted by the research team at the Medical Informatics Unit of the University of Cambridge, which show that the Ballistocardiogram (BCG) has prognostic value in detecting impaired left ventricular function before it becomes clinically overt as myocardial infarction leading to sudden death. The objective of this study is to develop and demonstrate a framework for realising an on-line BCG signal classification model in a portable device that would have the potential to find pathological signs as early as possible for home health care. Two new on-line automatic BeG classification models for time domain BeG classification are proposed. Both systems are based on a two stage process: input feature extraction followed by a neural classifier. One system uses a principal component analysis neural network, and the other a discrete wavelet transform, to reduce the input dimensionality. Results of the classification, dimensionality reduction, and comparison are presented. It is indicated that the combined wavelet transform and MLP system has a more reliable performance than the combined neural networks system, in situations where the data available to determine the network parameters is limited. Moreover, the wavelet transfonn requires no prior knowledge of the statistical distribution of data samples and the computation complexity and training time are reduced. Overall, a methodology for realising an automatic BeG classification system for a portable instrument is presented. A fully paralJel neural network design for a low cost platform using field programmable gate arrays (Xilinx's XC4000 series) is explored. This addresses the potential speed requirements in the biomedical signal processing field. It also demonstrates a flexible hardware design approach so that an instrument's parameters can be updated as data expands with time. To reduce the hardware design complexity and to increase the system performance, a hybrid learning algorithm using random optimisation and the backpropagation rule is developed to achieve an efficient weight update mechanism in low weight precision learning. The simulation results show that the hybrid learning algorithm is effective in solving the network paralysis problem and the convergence is much faster than by the standard backpropagation rule. The hidden and output layer nodes have been mapped on Xilinx FPGAs with automatic placement and routing tools. The static time analysis results suggests that the proposed network implementation could generate 2.7 billion connections per second performance

Doctor of Philosophy

dissertationThe goal of this work is to construct a simulation toolset for studying and improving neuroprosthetic devices for restoring neural functionality to patients with neural disorders or diseases. This involves the construction and validation of coupled electromagnetic-neural computational models of retina and hippocampus, compiling knowledge from a broad multidisciplinary background into a single computational platform, with features specific to implant electronics, bulk tissue, cellular and neural network behavior, and diseased tissue. The application of a retina prosthetic device for restoring partial vision to patients blinded by degenerative diseases was first considered. This began with the conceptualization of the retina model, translating features of a connectome, implant electronics, and medical images into a computational model that was "degenerated." It was then applied to the design of novel electrode geometries towards increasing the resolution of induced visual percept, and of stimulation waveform shapes for increasing control of induced neural activity in diseased retina. Throughout this process, features of the simulation toolset itself were modified to increase the precision of the results, leading to a novel method for computing effective bulk resistivity for use in such multiscale modeling. This simulation strategy was then extended to the application of a hippocampus prosthetic device, which has been proposed to restore and/or enhance memory in patients with memory disorders such as Alzheimer's disease or dementia. Using this multiscale modeling approach, we are able to provide recommendations for electrode geometry, placement, and stimulation magnitude for increased safety and efficacy in future experimental trials. In attempt to model neural activity in dense hippocampal tissue, a simulation platform for considering the effects the electrical activity of neural networks have on the extracellular electric field, and therefore have on their neighboring cells, was constructed, further increasing the predictive ability of the proposed methodology for modeling electrical stimulation of neural tissue