Multiobjective genetic algorithm strategies for electricity production from generation IV nuclear technology

Development of a technico-economic optimization strategy of cogeneration systems of electricity/hydrogen, consists in finding an optimal efficiency of the generating cycle and heat delivery system, maximizing the energy production and minimizing the production costs. The first part of the paper is related to the development of a multiobjective optimization library (MULTIGEN) to tackle all types of problems arising from cogeneration. After a literature review for identifying the most efficient methods, the MULTIGEN library is described, and the innovative points are listed. A new stopping criterion, based on the stagnation of the Pareto front, may lead to significant decrease of computational times, particularly in the case of problems involving only integer variables. Two practical examples are presented in the last section. The former is devoted to a bicriteria optimization of both exergy destruction and total cost of the plant, for a generating cycle coupled with a Very High Temperature Reactor (VHTR). The second example consists in designing the heat exchanger of the generating turbomachine. Three criteria are optimized: the exchange surface, the exergy destruction and the number of exchange modules

Hybrid behavioural-based multi-objective space trajectory optimization

In this chapter we present a hybridization of a stochastic based search approach for multi-objective optimization with a deterministic domain decomposition of the solution space. Prior to the presentation of the algorithm we introduce a general formulation of the optimization problem that is suitable to describe both single and multi-objective problems. The stochastic approach, based on behaviorism, combinedwith the decomposition of the solutions pace was tested on a set of standard multi-objective optimization problems and on a simple but representative case of space trajectory design

On the evolutionary optimisation of many conflicting objectives

This inquiry explores the effectiveness of a class of modern evolutionary algorithms, represented by Non-dominated Sorting Genetic Algorithm (NSGA) components, for solving optimisation tasks with many conflicting objectives. Optimiser behaviour is assessed for a grid of mutation and recombination operator configurations. Performance maps are obtained for the dual aims of proximity to, and distribution across, the optimal trade-off surface. Performance sweet-spots for both variation operators are observed to contract as the number of objectives is increased. Classical settings for recombination are shown to be suitable for small numbers of objectives but correspond to very poor performance for higher numbers of objectives, even when large population sizes are used. Explanations for this behaviour are offered via the concepts of dominance resistance and active diversity promotion

Optimization of Heterogeneous UAV Communications Using the Multiobjective Quadratic Assignment Problem

The Air Force has placed a high priority on developing new and innovative ways to use Unmanned Aerial Vehicles (UAVs). The Defense Advanced Research Projects Agency (DARPA) currently funds many projects that deal with the advancement of UAV research. The ultimate goal of the Air Force is to use UAVs in operations that are highly dangerous to pilots, mainly the suppression of enemy air defenses (SEAD). With this goal in mind, formation structuring of autonomous or semi-autonomous UAVs is of future importance. This particular research investigates the optimization of heterogeneous UAV multi-channel communications in formation. The problem maps to the multiobjective Quadratic Assignment Problem (mQAP). Optimization of this problem is done through the use of a Multiobjective Evolutionary Algorithm (MOEA) called the Multiobjective Messy Genetic Algorithm - II (MOMGA-II). Experimentation validates the attainment of an acceptable Pareto Front for a variety of mQAP benchmarks. It was observed that building block size can affect the location vectors along the current Pareto Front. The competitive templates used during testing perform best when they are randomized before each building block size evaluation. This tuning of the MOMGA-II parameters creates a more effective algorithm for the variety of mQAP benchmarks, when compared to the initial experiments. Thus this algorithmic approach would be useful for Air Force decision makers in determining the placement of UAVs in formations

Multiobjective strategies for New Product Development in the pharmaceutical industry

New Product Development (NPD) constitutes a challenging problem in the pharmaceutical industry, due to the characteristics of the development pipeline. Formally, the NPD problem can be stated as follows: select a set of R&D projects from a pool of candidate projects in order to satisfy several criteria (economic profitability, time to market) while coping with the uncertain nature of the projects. More precisely, the recurrent key issues are to determine the projects to develop once target molecules have been identified, their order and the level of resources to assign. In this context, the proposed approach combines discrete event stochastic simulation (Monte Carlo approach) with multiobjective genetic algorithms (NSGAII type, Non-Sorted Genetic Algorithm II) to optimize the highly combinatorial portfolio management problem. In that context, Genetic Algorithms (GAs) are particularly attractive for treating this kind of problem, due to their ability to directly lead to the so-called Pareto front and to account for the combinatorial aspect. This work is illustrated with a study case involving nine interdependent new product candidates targeting three diseases. An analysis is performed for this test bench on the different pairs of criteria both for the bi- and tricriteria optimization: large portfolios cause resource queues and delays time to launch and are eliminated by the bi- and tricriteria optimization strategy. The optimization strategy is thus interesting to detect the sequence candidates. Time is an important criterion to consider simultaneously with NPV and risk criteria. The order in which drugs are released in the pipeline is of great importance as with scheduling problems

Regularization-free multicriteria optimization of polymer viscoelasticity model

This paper introduces a multiobjective optimization (MOP) method for nonlinear regression analysis which is capable of simultaneously minimizing the model order and estimating parameter values without the need of exogenous regularization constraints. The method is introduced through a case study in polymer rheology modeling. Prevailing approaches in this field tackle conflicting optimization goals as a monobjective problem by aggregating individual regression errors on each dependent variable into a single weighted scalarization function. In addition, their supporting deterministic numerical methods often rely on assumptions which are extrinsic to the problem, such as regularization constants and restrictions on parameter distribution, thereby introducing methodology inherent biases into the model. Our proposed non-deterministic MOP strategy, on the other hand, aims at finding the Pareto-front of all optimal solutions with respect not only to individual regression errors, but also to the number of parameters needed to fit the data, automatically reducing the model order. The evolutionary computation approach does not require arbitrary constraints on objective weights, regularization parameters or other exogenous assumptions to handle the ill-posed inverse problem. The article discusses the method rationales, implementation, simulation experiments, and comparison with other methods, with experimental evidences that it can outperform state-of-art techniques. While the discussion focuses on the study case, the introduced method is general and immediately applicable to other problem domains.This work is funded by National Funds through FCT - Portuguese Foundation for Science and Technology, References UIDB/05256/2020 and UIDP/05256/2020 and the European project MSCA-RISE-2015, NEWEX, Reference 734205

Multiobjective strategies for New Product Development in the pharmaceutical industry

New Product Development (NPD) constitutes a challenging problem in the pharmaceutical industry, due to the characteristics of the development pipeline. Formally, the NPD problem can be stated as follows: select a set of R&D projects from a pool of candidate projects in order to satisfy several criteria (economic profitability, time to market) while coping with the uncertain nature of the projects. More precisely, the recurrent key issues are to determine the projects to develop once target molecules have been identified, their order and the level of resources to assign. In this context, the proposed approach combines discrete event stochastic simulation (Monte Carlo approach) with multiobjective genetic algorithms (NSGAII type, Non-Sorted Genetic Algorithm II) to optimize the highly combinatorial portfolio management problem. In that context, Genetic Algorithms (GAs) are particularly attractive for treating this kind of problem, due to their ability to directly lead to the so-called Pareto front and to account for the combinatorial aspect. This work is illustrated with a study case involving nine interdependent new product candidates targeting three diseases. An analysis is performed for this test bench on the different pairs of criteria both for the bi- and tricriteria optimization: large portfolios cause resource queues and delays time to launch and are eliminated by the bi- and tricriteria optimization strategy. The optimization strategy is thus interesting to detect the sequence candidates. Time is an important criterion to consider simultaneously with NPV and risk criteria. The order in which drugs are released in the pipeline is of great importance as with scheduling problems