Review : Deep learning in electron microscopy

Deep learning is transforming most areas of science and technology, including electron microscopy. This review paper offers a practical perspective aimed at developers with limited familiarity. For context, we review popular applications of deep learning in electron microscopy. Following, we discuss hardware and software needed to get started with deep learning and interface with electron microscopes. We then review neural network components, popular architectures, and their optimization. Finally, we discuss future directions of deep learning in electron microscopy

Computational Imaging and Artificial Intelligence: The Next Revolution of Mobile Vision

Signal capture stands in the forefront to perceive and understand the environment and thus imaging plays the pivotal role in mobile vision. Recent explosive progresses in Artificial Intelligence (AI) have shown great potential to develop advanced mobile platforms with new imaging devices. Traditional imaging systems based on the "capturing images first and processing afterwards" mechanism cannot meet this unprecedented demand. Differently, Computational Imaging (CI) systems are designed to capture high-dimensional data in an encoded manner to provide more information for mobile vision systems.Thanks to AI, CI can now be used in real systems by integrating deep learning algorithms into the mobile vision platform to achieve the closed loop of intelligent acquisition, processing and decision making, thus leading to the next revolution of mobile vision.Starting from the history of mobile vision using digital cameras, this work first introduces the advances of CI in diverse applications and then conducts a comprehensive review of current research topics combining CI and AI. Motivated by the fact that most existing studies only loosely connect CI and AI (usually using AI to improve the performance of CI and only limited works have deeply connected them), in this work, we propose a framework to deeply integrate CI and AI by using the example of self-driving vehicles with high-speed communication, edge computing and traffic planning. Finally, we outlook the future of CI plus AI by investigating new materials, brain science and new computing techniques to shed light on new directions of mobile vision systems

Curvature regularization for Non-line-of-sight Imaging from Under-sampled Data

Non-line-of-sight (NLOS) imaging aims to reconstruct the three-dimensional hidden scenes from the data measured in the line-of-sight, which uses photon time-of-flight information encoded in light after multiple diffuse reflections. The under-sampled scanning data can facilitate fast imaging. However, the resulting reconstruction problem becomes a serious ill-posed inverse problem, the solution of which is of high possibility to be degraded due to noises and distortions. In this paper, we propose two novel NLOS reconstruction models based on curvature regularization, i.e., the object-domain curvature regularization model and the dual (i.e., signal and object)-domain curvature regularization model. Fast numerical optimization algorithms are developed relying on the alternating direction method of multipliers (ADMM) with the backtracking stepsize rule, which are further accelerated by GPU implementation. We evaluate the proposed algorithms on both synthetic and real datasets, which achieve state-of-the-art performance, especially in the compressed sensing setting. All our codes and data are available at https://github.com/Duanlab123/CurvNLOS

A deep learning theory for neural networks grounded in physics

Au cours de la dernière décennie, l'apprentissage profond est devenu une composante majeure de l'intelligence artificielle, ayant mené à une série d'avancées capitales dans une variété de domaines. L'un des piliers de l'apprentissage profond est l'optimisation de fonction de coût par l'algorithme du gradient stochastique (SGD). Traditionnellement en apprentissage profond, les réseaux de neurones sont des fonctions mathématiques différentiables, et les gradients requis pour l'algorithme SGD sont calculés par rétropropagation. Cependant, les architectures informatiques sur lesquelles ces réseaux de neurones sont implémentés et entraînés souffrent d’inefficacités en vitesse et en énergie, dues à la séparation de la mémoire et des calculs dans ces architectures. Pour résoudre ces problèmes, le neuromorphique vise à implementer les réseaux de neurones dans des architectures qui fusionnent mémoire et calculs, imitant plus fidèlement le cerveau. Dans cette thèse, nous soutenons que pour construire efficacement des réseaux de neurones dans des architectures neuromorphiques, il est nécessaire de repenser les algorithmes pour les implémenter et les entraîner. Nous présentons un cadre mathématique alternative, compatible lui aussi avec l’algorithme SGD, qui permet de concevoir des réseaux de neurones dans des substrats qui exploitent mieux les lois de la physique. Notre cadre mathématique s'applique à une très large classe de modèles, à savoir les systèmes dont l'état ou la dynamique sont décrits par des équations variationnelles. La procédure pour calculer les gradients de la fonction de coût dans de tels systèmes (qui dans de nombreux cas pratiques ne nécessite que de l'information locale pour chaque paramètre) est appelée “equilibrium propagation” (EqProp). Comme beaucoup de systèmes en physique et en ingénierie peuvent être décrits par des principes variationnels, notre cadre mathématique peut potentiellement s'appliquer à une grande variété de systèmes physiques, dont les applications vont au delà du neuromorphique et touchent divers champs d'ingénierie.In the last decade, deep learning has become a major component of artificial intelligence, leading to a series of breakthroughs across a wide variety of domains. The workhorse of deep learning is the optimization of loss functions by stochastic gradient descent (SGD). Traditionally in deep learning, neural networks are differentiable mathematical functions, and the loss gradients required for SGD are computed with the backpropagation algorithm. However, the computer architectures on which these neural networks are implemented and trained suffer from speed and energy inefficiency issues, due to the separation of memory and processing in these architectures. To solve these problems, the field of neuromorphic computing aims at implementing neural networks on hardware architectures that merge memory and processing, just like brains do. In this thesis, we argue that building large, fast and efficient neural networks on neuromorphic architectures also requires rethinking the algorithms to implement and train them. We present an alternative mathematical framework, also compatible with SGD, which offers the possibility to design neural networks in substrates that directly exploit the laws of physics. Our framework applies to a very broad class of models, namely those whose state or dynamics are described by variational equations. This includes physical systems whose equilibrium state minimizes an energy function, and physical systems whose trajectory minimizes an action functional (principle of least action). We present a simple procedure to compute the loss gradients in such systems, called equilibrium propagation (EqProp), which requires solely locally available information for each trainable parameter. Since many models in physics and engineering can be described by variational principles, our framework has the potential to be applied to a broad variety of physical systems, whose applications extend to various fields of engineering, beyond neuromorphic computing

Gravitational Lenses as High-Resolution Telescopes

The inner regions of active galaxies host the most extreme and energetic phenomena in the universe including, relativistic jets, supermassive black hole binaries, and recoiling supermassive black holes. However, many of these sources cannot be resolved with direct observations. I review how strong gravitational lensing can be used to elucidate the structures of these sources from radio frequencies up to very high energy gamma rays. The deep gravitational potentials surrounding galaxies act as natural gravitational lenses. These gravitational lenses split background sources into multiple images, each with a gravitationally-induced time delay. These time delays and positions of lensed images depend on the source location, and thus, can be used to infer the spatial origins of the emission. For example, using gravitationally-induced time delays improves angular resolution of modern gamma-ray instruments by six orders of magnitude, and provides evidence that gamma-ray outbursts can be produced at even thousands of light years from a supermassive black hole, and that the compact radio emission does not always trace the position of the supermassive black hole. These findings provide unique physical information about the central structure of active galaxies, force us to revise our models of operating particle acceleration mechanisms, and challenge our assumptions about the origin of compact radio emission. Future surveys, including LSST, SKA, and Euclid, will provide observations for hundreds of thousands of gravitationally lensed sources, which will allow us to apply strong gravitational lensing to study the multi-wavelength structure for large ensembles of sources. This large ensemble of gravitationally lensed active galaxies will allow us to elucidate the physical origins of multi-wavelength emissions, their connections to supermassive black holes, and their cosmic evolution.Comment: Invited (Accepted) review for Physics Report

Mean-Field methods for Structured Deep-Learning in Computer Vision

In recent years, Machine Learning based Computer Vision techniques made impressive progress. These algorithms proved particularly efficient for image classification or detection of isolated objects. From a probabilistic perspective, these methods can predict marginals, over single or multiple variables, independently, with high accuracy. However, in many tasks of practical interest, we need to predict jointly several correlated variables. Practical applications include people detection in crowded scenes, image segmentation, surface reconstruction, 3D pose estimation and others. A large part of the research effort in today's computer-vision community aims at finding task-specific solutions to these problems, while leveraging the power of Deep-Learning based classifiers. In this thesis, we present our journey towards a generic and practical solution based on mean-field (MF) inference. Mean-field is a Statistical Physics-inspired method which has long been used in Computer-Vision as a variational approximation to posterior distributions over complex Conditional Random Fields. Standard mean-field optimization is based on coordinate descent and in many situations can be impractical. We therefore propose a novel proximal gradient-based approach to optimizing the variational objective. It is naturally parallelizable and easy to implement. We prove its convergence, and then demonstrate that, in practice, it yields faster convergence and often finds better optima than more traditional mean-field optimization techniques. Then, we show that we can replace the fully factorized distribution of mean-field by a weighted mixture of such distributions, that similarly minimizes the KL-Divergence to the true posterior. Our extension of the clamping method proposed in previous works allows us to both produce a more descriptive approximation of the true posterior and, inspired by the diverse MAP paradigms, fit a mixture of mean-field approximations. We demonstrate that this positively impacts real-world algorithms that initially relied on mean-fields. One of the important properties of the mean-field inference algorithms is that the closed-form updates are fully differentiable operations. This naturally allows to do parameter learning by simply unrolling multiple iterations of the updates, the so-called back-mean-field algorithm. We derive a novel and efficient structured learning method for multi-modal posterior distribution based on the Multi-Modal Mean-Field approximation, which can be seamlessly combined to modern gradient-based learning methods such as CNNs. Finally, we explore in more details the specific problem of structured learning and prediction for multiple-people detection in crowded scenes. We then present a mean-field based structured deep-learning detection algorithm that provides state of the art results on this dataset

The Telecommunications and Data Acquisition Report

This publication, one of a series formerly titled The Deep Space Network Progress Report, documents DSN progress in flight project support, tracking and data acquisition research and technology, network engineering, hardware and software implementation, and operations. In addition, developments in Earth-based radio technology as applied to geodynamics, astrophysics and the radio search for extraterrestrial intelligence are reported

Survey on Fully Homomorphic Encryption, Theory, and Applications

Data privacy concerns are increasing significantly in the context of Internet of Things, cloud services, edge computing, artificial intelligence applications, and other applications enabled by next generation networks. Homomorphic Encryption addresses privacy challenges by enabling multiple operations to be performed on encrypted messages without decryption. This paper comprehensively addresses homomorphic encryption from both theoretical and practical perspectives. The paper delves into the mathematical foundations required to understand fully homomorphic encryption (FHE). It consequently covers design fundamentals and security properties of FHE and describes the main FHE schemes based on various mathematical problems. On a more practical level, the paper presents a view on privacy-preserving Machine Learning using homomorphic encryption, then surveys FHE at length from an engineering angle, covering the potential application of FHE in fog computing, and cloud computing services. It also provides a comprehensive analysis of existing state-of-the-art FHE libraries and tools, implemented in software and hardware, and the performance thereof