Deformable dilated faster R-CNN for universal lesion detection in CT images

A paper in EMBC 202

CLIP-Driven Universal Model for Organ Segmentation and Tumor Detection

An increasing number of public datasets have shown a marked impact on automated organ segmentation and tumor detection. However, due to the small size and partially labeled problem of each dataset, as well as a limited investigation of diverse types of tumors, the resulting models are often limited to segmenting specific organs/tumors and ignore the semantics of anatomical structures, nor can they be extended to novel domains. To address these issues, we propose the CLIP-Driven Universal Model, which incorporates text embedding learned from Contrastive Language-Image Pre-training (CLIP) to segmentation models. This CLIP-based label encoding captures anatomical relationships, enabling the model to learn a structured feature embedding and segment 25 organs and 6 types of tumors. The proposed model is developed from an assembly of 14 datasets, using a total of 3,410 CT scans for training and then evaluated on 6,162 external CT scans from 3 additional datasets. We rank first on the Medical Segmentation Decathlon (MSD) public leaderboard and achieve state-of-the-art results on Beyond The Cranial Vault (BTCV). Additionally, the Universal Model is computationally more efficient (6x faster) compared with dataset-specific models, generalized better to CT scans from varying sites, and shows stronger transfer learning performance on novel tasks.Comment: Rank first in Medical Segmentation Decathlon (MSD) Competitio

Anomaly Detection in Medical Time Series with Generative Adversarial Networks: A Selective Review

Anomaly detection in medical data is often of critical importance, from diagnosing and potentially localizing disease processes such as epilepsy to detecting and preventing fatal events such as cardiac arrhythmias. Generative adversarial networks (GANs) have since their inception shown promise in various applications and have been shown to be effective in cybersecurity, data denoising, and data augmentation, and have more recently found a potentially important place in the detection of anomalies in medical time series. This chapter provides a selective review of this novel use of GANs, in the process highlighting the nature of anomalies in time series, special challenges related to medical time series, and some general issues in approaching time series anomaly detection with deep learning. We cover the most frequently applied GAN models and briefly detail the current landscape of applying GANs to anomaly detection in two commonly used medical time series, electrocardiography (ECG) and electroencephalography (EEG)