19,619 research outputs found
Two-Stage Eagle Strategy with Differential Evolution
Efficiency of an optimization process is largely determined by the search
algorithm and its fundamental characteristics. In a given optimization, a
single type of algorithm is used in most applications. In this paper, we will
investigate the Eagle Strategy recently developed for global optimization,
which uses a two-stage strategy by combing two different algorithms to improve
the overall search efficiency. We will discuss this strategy with differential
evolution and then evaluate their performance by solving real-world
optimization problems such as pressure vessel and speed reducer design. Results
suggest that we can reduce the computing effort by a factor of up to 10 in many
applications
Bat Algorithm: Literature Review and Applications
Bat algorithm (BA) is a bio-inspired algorithm developed by Yang in 2010 and
BA has been found to be very efficient. As a result, the literature has
expanded significantly in the last 3 years. This paper provides a timely review
of the bat algorithm and its new variants. A wide range of diverse applications
and case studies are also reviewed and summarized briefly here. Further
research topics are also discussed.Comment: 10 page
Review of Metaheuristics and Generalized Evolutionary Walk Algorithm
Metaheuristic algorithms are often nature-inspired, and they are becoming
very powerful in solving global optimization problems. More than a dozen of
major metaheuristic algorithms have been developed over the last three decades,
and there exist even more variants and hybrid of metaheuristics. This paper
intends to provide an overview of nature-inspired metaheuristic algorithms,
from a brief history to their applications. We try to analyze the main
components of these algorithms and how and why they works. Then, we intend to
provide a unified view of metaheuristics by proposing a generalized
evolutionary walk algorithm (GEWA). Finally, we discuss some of the important
open questions.Comment: 14 page
EAGLE multi-object AO concept study for the E-ELT
EAGLE is the multi-object, spatially-resolved, near-IR spectrograph
instrument concept for the E-ELT, relying on a distributed Adaptive Optics,
so-called Multi Object Adaptive Optics. This paper presents the results of a
phase A study. Using 84x84 actuator deformable mirrors, the performed analysis
demonstrates that 6 laser guide stars and up to 5 natural guide stars of
magnitude R<17, picked-up in a 7.3' diameter patrol field of view, allow us to
obtain an overall performance in terms of Ensquared Energy of 35% in a 75x75
mas^2 spaxel at H band, whatever the target direction in the centred 5' science
field for median seeing conditions. The computed sky coverage at galactic
latitudes |b|~60 is close to 90%.Comment: 6 pages, to appear in the proceedings of the AO4ELT conference, held
in Paris, 22-26 June 200
A Study of Interwell Interference and Well Performance in Unconventional Reservoirs Based on Coupled Flow and Geomechanics Modeling with Improved Computational Efficiency
Completion quality of tightly spaced horizontal wells in unconventional reservoirs is important for hydrocarbon recovery efficiency. Parent well production usually leads to heterogeneous stress evolution around parent wells and at infill well locations, which affects hydraulic fracture growth along infill wells. Recent field observations indicate that infill well completions lead to frac hits and production interference between parent and infill wells. Therefore, it is important to characterize the heterogeneous interwell stress/pressure evolutions and hydraulic fracture networks. This work presents a reservoir-geomechanics-fracturing modeling workflow and its implementation in unconventional reservoirs for the characterization of interwell stress and pressure evolutions and for the modeling of interwell hydraulic fracture geometry.
An in-house finite element model coupling fluid flow and geomechanics is first introduced and used to characterize production-induced stress and pressure changes in the reservoir. Then, an in-house complex fracture propagation model coupling fracture mechanics and wellbore/fracture fluid flow is used for the simulation of hydraulic fractures along infill wells. A parallel solver is also implemented in a reservoir geomechanics simulator in a separate study to investigate the potential of improving computational efficiency.
Results show that differential stress (DS), parent well fracture geometry, legacy production time, bottomhole pressure (BHP) for legacy production, and perforation cluster location are key parameters affecting interwell fracture geometry and the occurrence of
frac hits. In general, transverse infill well fractures are obtained in scenarios with large DS and small legacy producing time/BHP. Non-uniform parent well fracture geometry leads to frac hits in certain cases, while the assumption of uniform parent well fracture half-lengths in the numerical model could not capture the phenomenon of frac hits. Perforation cluster locations along infill wells do not play an important role in determining whether an infill well hydraulic fracture is transverse, while they are important for the occurrence of frac hits.
In addition, the implementation of a parallel solver, PETSc, in a fortran-based simulator indicates that an overall speedup of 14 can be achieved for simulations with one million grid blocks. This result provides a reference for improving computational efficiency for geomechanical simulation involving large matrices using finite element methods (FEM)
Multiwavelength Studies of Young OB Associations
We discuss how contemporary multiwavelength observations of young
OB-dominated clusters address long-standing astrophysical questions: Do
clusters form rapidly or slowly with an age spread? When do clusters expand and
disperse to constitute the field star population? Do rich clusters form by
amalgamation of smaller subclusters? What is the pattern and duration of
cluster formation in massive star forming regions (MSFRs)? Past observational
difficulties in obtaining good stellar censuses of MSFRs have been alleviated
in recent studies that combine X-ray and infrared surveys to obtain rich,
though still incomplete, censuses of young stars in MSFRs. We describe here one
of these efforts, the MYStIX project, that produced a catalog of 31,784
probable members of 20 MSFRs. We find that age spread within clusters are real
in the sense that the stars in the core formed after the cluster halo. Cluster
expansion is seen in the ensemble of (sub)clusters, and older dispersing
populations are found across MSFRs. Direct evidence for subcluster merging is
still unconvincing. Long-lived, asynchronous star formation is pervasive across
MSFRs.Comment: 22 pages, 9 figures. To appear in "The Origin of Stellar Clusters",
edited by Steven Stahler, Springer, 2017, in pres
Poland''s Jobless Growth: A Temporary Cure?
Poland's post-communist economic performance has been generally good. However, for many years its growth was jobless, it exhibited very high unemployment rates and concomitantly made little progress in approaching the targets set for EU Member States under the Lisbon Strategy. Unexpectedly, in 2003 the country's labour market began to exhibit a new dynamism, with employment growing strongly and unemployment tumbling. This apparent improvement coincided with a liberalisation of its Labour Code. Unfortunately, the measures introduced to increase flexibility are seemingly at variance with the EU's Fixed-Term Work Directive and might need to be modified.
Expression of Transposable Elements in Neural Tissues during Xenopus Development
Transposable elements comprise a large proportion of animal genomes. Transposons can have detrimental effects on genome stability but also offer positive roles for genome evolution and gene expression regulation. Proper balance of the positive and deleterious effects of transposons is crucial for cell homeostasis and requires a mechanism that tightly regulates their expression. Herein we describe the expression of DNA transposons of the Tc1/mariner superfamily during Xenopus development. Sense and antisense transcripts containing complete Tc1-2_Xt were detected in Xenopus embryos. Both transcripts were found in zygotic stages and were mainly localized in Spemann's organizer and neural tissues. In addition, the Tc1-like elements Eagle, Froggy, Jumpy, Maya, Xeminos and TXr were also expressed in zygotic stages but not oocytes in X. tropicalis. Interestingly, although Tc1-2_Xt transcripts were not detected in Xenopus laevis embryos, transcripts from other two Tc1-like elements (TXr and TXz) presented a similar temporal and spatial pattern during X. laevis development. Deep sequencing analysis of Xenopus tropicalis gastrulae showed that PIWI-interacting RNAs (piRNAs) are specifically derived from several Tc1-like elements. The localized expression of Tc1-like elements in neural tissues suggests that they could play a role during the development of the Xenopus nervous system
Improved split fluorescent proteins for endogenous protein labeling.
Self-complementing split fluorescent proteins (FPs) have been widely used for protein labeling, visualization of subcellular protein localization, and detection of cell-cell contact. To expand this toolset, we have developed a screening strategy for the direct engineering of self-complementing split FPs. Via this strategy, we have generated a yellow-green split-mNeonGreen21-10/11 that improves the ratio of complemented signal to the background of FP1-10-expressing cells compared to the commonly used split GFP1-10/11; as well as a 10-fold brighter red-colored split-sfCherry21-10/11. Based on split sfCherry2, we have engineered a photoactivatable variant that enables single-molecule localization-based super-resolution microscopy. We have demonstrated dual-color endogenous protein tagging with sfCherry211 and GFP11, revealing that endoplasmic reticulum translocon complex Sec61B has reduced abundance in certain peripheral tubules. These new split FPs not only offer multiple colors for imaging interaction networks of endogenous proteins, but also hold the potential to provide orthogonal handles for biochemical isolation of native protein complexes.Split fluorescent proteins (FPs) have been widely used to visualise proteins in cells. Here the authors develop a screen for engineering new split FPs, and report a yellow-green split-mNeonGreen2 with reduced background, a red split-sfCherry2 for multicolour labeling, and its photoactivatable variant for super-resolution use
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