PadChest: A large chest x-ray image dataset with multi-label annotated reports

We present a labeled large-scale, high resolution chest x-ray dataset for the automated exploration of medical images along with their associated reports. This dataset includes more than 160,000 images obtained from 67,000 patients that were interpreted and reported by radiologists at Hospital San Juan Hospital (Spain) from 2009 to 2017, covering six different position views and additional information on image acquisition and patient demography. The reports were labeled with 174 different radiographic findings, 19 differential diagnoses and 104 anatomic locations organized as a hierarchical taxonomy and mapped onto standard Unified Medical Language System (UMLS) terminology. Of these reports, 27% were manually annotated by trained physicians and the remaining set was labeled using a supervised method based on a recurrent neural network with attention mechanisms. The labels generated were then validated in an independent test set achieving a 0.93 Micro-F1 score. To the best of our knowledge, this is one of the largest public chest x-ray database suitable for training supervised models concerning radiographs, and the first to contain radiographic reports in Spanish. The PadChest dataset can be downloaded from http://bimcv.cipf.es/bimcv-projects/padchest/

Feature Detection in Medical Images Using Deep Learning

This project explores the use of deep learning to predict age based on pediatric hand X-Rays. Data from the Radiological Society of North America’s pediatric bone age challenge were used to train and evaluate a convolutional neural network. The project used InceptionV3, a CNN developed by Google, that was pre-trained on ImageNet, a popular online image dataset. Our fine-tuned version of InceptionV3 yielded an average error of less than 10 months between predicted and actual age. This project shows the effectiveness of deep learning in analyzing medical images and the potential for even greater improvements in the future. In addition to the technological and potential clinical benefits of these methods, this project will serve as a useful pedagogical tool for introducing the challenges and applications of deep learning to the Bryant community

A Convolutional Neural Network for the Automatic Diagnosis of Collagen VI related Muscular Dystrophies

The development of machine learning systems for the diagnosis of rare diseases is challenging mainly due the lack of data to study them. Despite this challenge, this paper proposes a system for the Computer Aided Diagnosis (CAD) of low-prevalence, congenital muscular dystrophies from confocal microscopy images. The proposed CAD system relies on a Convolutional Neural Network (CNN) which performs an independent classification for non-overlapping patches tiling the input image, and generates an overall decision summarizing the individual decisions for the patches on the query image. This decision scheme points to the possibly problematic areas in the input images and provides a global quantitative evaluation of the state of the patients, which is fundamental for diagnosis and to monitor the efficiency of therapies.Comment: Submitted for review to Expert Systems With Application

Tuberculosis Prediction by Machine Learning Techniques

Tuberculosis is one of the top reasons of death all over the planet. Mycobacterium tuberculosis, bacteria that infects the lungs, is what causes it. For professionals working in the medical field, accurately identifying and timely predicting tuberculosis are major challenges. The course of treatment also varies from patient to patient since occasionally a patient develops drug resistance. Doctors will be given algorithmic support while using machine learning to help them diagnose, treat patients appropriately, and make quicker and better judgments. This paper discusses the many tuberculosis causes and symptoms as well as how accurate and fast prediction and diagnostic investigations have been carried out in recent years with the aid of machine learning (ML) technique

A Multi-model Approach in Developing an Intelligent Assistant for Diagnosis Recommendation in Clinical Health Systems

Clinical health information systems capture massive amounts of unstructured data from various health and medical facilities. This study utilizes unstructured patient clinical text data to develop an intelligent assistant that can identify possible related diagnoses based on a given text input. The approach applies a one-vs-rest binary classification technique wherein given an input text data, it is identified whether it can be positively or negatively classified for a given diagnosis. Multi-layer Feed-Forward Neural Network models were developed for each individual diagnosis case. The task of the intelligent assistant is to iterate over all the different models and return those that output a positive diagnosis. To validate the performance of the models, the performance metrics were compared against Naive Bayes, Decision Trees, and K-Nearest Neighbor. The results show that the neural network learner provided better performance scores in both accuracy and area under the curve metric scores. Further, testing on multiple diagnoses also shows that the methodology for developing the diagnosis models can be replicated for development of models for other diseases as well