Tailoring Fibre Structure Enabled by X-ray Analytics for Targeted Biomedical Applications

The rising interest in designing fibres via spinning techniques combining the properties of various polymeric materials into advanced functionalised materials is directed towards targeted biomedical applications such as drug delivery, wearable sensors or tissue engineering. Understanding how these functional polymers exhibit multiscale structures ranging from the molecular level to nano-, micro-and millimetre scale is a key prerequisite for their challenging applications that can be addressed by a non-destructive X-ray based analytical approach. X-ray multimodalities combining X-ray imaging, scattering and diffraction allow the study of morphology, molecular structure, and the analysis of nano-domain size and shape, crystallinity and preferential orientation in 3D arrangements. The incorporation of X-ray analytics in the design process of polymeric fibers via their nanostructure under non-ambient conditions (i.e. temperature, mechanical load, humidity…) allows for efficient optimization of the fabrication process as well as quality control along the product lifetime under operating environmental conditions. Here, we demonstrate the successful collaboration between the laboratory of Biomimetic Textiles and Membranes and the Center of X-ray Analytics at Empa for the design, characterisation and optimisation of advanced functionalised polymeric fibrous material systems

Feedback methods for inverse simulation of dynamic models for engineering systems applications

Inverse simulation is a form of inverse modelling in which computer simulation methods are used to find the time histories of input variables that, for a given model, match a set of required output responses. Conventional inverse simulation methods for dynamic models are computationally intensive and can present difficulties for high-speed applications. This paper includes a review of established methods of inverse simulation,giving some emphasis to iterative techniques that were first developed for aeronautical applications. It goes on to discuss the application of a different approach which is based on feedback principles. This feedback method is suitable for a wide range of linear and nonlinear dynamic models and involves two distinct stages. The first stage involves design of a feedback loop around the given simulation model and, in the second stage, that closed-loop system is used for inversion of the model. Issues of robustness within closed-loop systems used in inverse simulation are not significant as there are no plant uncertainties or external disturbances. Thus the process is simpler than that required for the development of a control system of equivalent complexity. Engineering applications of this feedback approach to inverse simulation are described through case studies that put particular emphasis on nonlinear and multi-input multi-output models

Feature-based Time Series Analytics

Time series analytics is a fundamental prerequisite for decision-making as well as automation and occurs in several applications such as energy load control, weather research, and consumer behavior analysis. It encompasses time series engineering, i.e., the representation of time series exhibiting important characteristics, and data mining, i.e., the application of the representation to a specific task. Due to the exhaustive data gathering, which results from the ``Industry 4.0'' vision and its shift towards automation and digitalization, time series analytics is undergoing a revolution. Big datasets with very long time series are gathered, which is challenging for engineering techniques. Traditionally, one focus has been on raw-data-based or shape-based engineering. They assess the time series' similarity in shape, which is only suitable for short time series. Another focus has been on model-based engineering. It assesses the time series' similarity in structure, which is suitable for long time series but requires larger models or a time-consuming modeling. Feature-based engineering tackles these challenges by efficiently representing time series and comparing their similarity in structure. However, current feature-based techniques are unsatisfactory as they are designed for specific data-mining tasks. In this work, we introduce a novel feature-based engineering technique. It efficiently provides a short representation of time series, focusing on their structural similarity. Based on a design rationale, we derive important time series characteristics such as the long-term and cyclically repeated characteristics as well as distribution and correlation characteristics. Moreover, we define a feature-based distance measure for their comparison. Both the representation technique and the distance measure provide desirable properties regarding storage and runtime. Subsequently, we introduce techniques based on our feature-based engineering and apply them to important data-mining tasks such as time series generation, time series matching, time series classification, and time series clustering. First, our feature-based generation technique outperforms state-of-the-art techniques regarding the accuracy of evolved datasets. Second, with our features, a matching method retrieves a match for a time series query much faster than with current representations. Third, our features provide discriminative characteristics to classify datasets as accurately as state-of-the-art techniques, but orders of magnitude faster. Finally, our features recommend an appropriate clustering of time series which is crucial for subsequent data-mining tasks. All these techniques are assessed on datasets from the energy, weather, and economic domains, and thus, demonstrate the applicability to real-world use cases. The findings demonstrate the versatility of our feature-based engineering and suggest several courses of action in order to design and improve analytical systems for the paradigm shift of Industry 4.0

AI and OR in management of operations: history and trends

The last decade has seen a considerable growth in the use of Artificial Intelligence (AI) for operations management with the aim of finding solutions to problems that are increasing in complexity and scale. This paper begins by setting the context for the survey through a historical perspective of OR and AI. An extensive survey of applications of AI techniques for operations management, covering a total of over 1200 papers published from 1995 to 2004 is then presented. The survey utilizes Elsevier's ScienceDirect database as a source. Hence, the survey may not cover all the relevant journals but includes a sufficiently wide range of publications to make it representative of the research in the field. The papers are categorized into four areas of operations management: (a) design, (b) scheduling, (c) process planning and control and (d) quality, maintenance and fault diagnosis. Each of the four areas is categorized in terms of the AI techniques used: genetic algorithms, case-based reasoning, knowledge-based systems, fuzzy logic and hybrid techniques. The trends over the last decade are identified, discussed with respect to expected trends and directions for future work suggested

A Taxonomy of Workflow Management Systems for Grid Computing

With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources. Such application scenarios require means for composing and executing complex workflows. Therefore, many efforts have been made towards the development of workflow management systems for Grid computing. In this paper, we propose a taxonomy that characterizes and classifies various approaches for building and executing workflows on Grids. We also survey several representative Grid workflow systems developed by various projects world-wide to demonstrate the comprehensiveness of the taxonomy. The taxonomy not only highlights the design and engineering similarities and differences of state-of-the-art in Grid workflow systems, but also identifies the areas that need further research.Comment: 29 pages, 15 figure

A Machine Learning Based Analytical Framework for Semantic Annotation Requirements

The Semantic Web is an extension of the current web in which information is given well-defined meaning. The perspective of Semantic Web is to promote the quality and intelligence of the current web by changing its contents into machine understandable form. Therefore, semantic level information is one of the cornerstones of the Semantic Web. The process of adding semantic metadata to web resources is called Semantic Annotation. There are many obstacles against the Semantic Annotation, such as multilinguality, scalability, and issues which are related to diversity and inconsistency in content of different web pages. Due to the wide range of domains and the dynamic environments that the Semantic Annotation systems must be performed on, the problem of automating annotation process is one of the significant challenges in this domain. To overcome this problem, different machine learning approaches such as supervised learning, unsupervised learning and more recent ones like, semi-supervised learning and active learning have been utilized. In this paper we present an inclusive layered classification of Semantic Annotation challenges and discuss the most important issues in this field. Also, we review and analyze machine learning applications for solving semantic annotation problems. For this goal, the article tries to closely study and categorize related researches for better understanding and to reach a framework that can map machine learning techniques into the Semantic Annotation challenges and requirements