Multivariate Analysis Applications in X-ray Diffraction

: Multivariate analysis (MA) is becoming a fundamental tool for processing in an efficient way the large amount of data collected in X-ray diffraction experiments. Multi-wedge data collections can increase the data quality in case of tiny protein crystals; in situ or operando setups allow investigating changes on powder samples occurring during repeated fast measurements; pump and probe experiments at X-ray free-electron laser (XFEL) sources supply structural characterization of fast photo-excitation processes. In all these cases, MA can facilitate the extraction of relevant information hidden in data, disclosing the possibility of automatic data processing even in absence of a priori structural knowledge. MA methods recently used in the field of X-ray diffraction are here reviewed and described, giving hints about theoretical background and possible applications. The use of MA in the framework of the modulated enhanced diffraction technique is described in detail

A Study of Myoelectric Signal Processing

This dissertation of various aspects of electromyogram (EMG: muscle electrical activity) signal processing is comprised of two projects in which I was the lead investigator and two team projects in which I participated. The first investigator-led project was a study of reconstructing continuous EMG discharge rates from neural impulses. Related methods for calculating neural firing rates in other contexts were adapted and applied to the intramuscular motor unit action potential train firing rate. Statistical results based on simulation and clinical data suggest that performances of spline-based methods are superior to conventional filter-based methods in the absence of decomposition error, but they unacceptably degrade in the presence of even the smallest decomposition errors present in real EMG data, which is typically around 3-5%. Optimal parameters for each method are found, and with normal decomposition error rates, ranks of these methods with their optimal parameters are given. Overall, Hanning filtering and Berger methods exhibit consistent and significant advantages over other methods. In the second investigator-led project, the technique of signal whitening was applied prior to motion classification of upper limb surface EMG signals previously collected from the forearm muscles of intact and amputee subjects. The motions classified consisted of 11 hand and wrist actions pertaining to prosthesis control. Theoretical models and experimental data showed that whitening increased EMG signal bandwidth by 65-75% and the coefficients of variation of temporal features computed from the EMG were reduced. As a result, a consistent classification accuracy improvement of 3-5% was observed for all subjects at small analysis durations (\u3c 100 ms). In the first team-based project, advanced modeling methods of the constant posture EMG-torque relationship about the elbow were studied: whitened and multi-channel EMG signals, training set duration, regularized model parameter estimation and nonlinear models. Combined, these methods reduced error to less than a quarter of standard techniques. In the second team-based project, a study related biceps-triceps surface EMG to elbow torque at seven joint angles during constant-posture contractions. Models accounting for co-contraction estimated that individual flexion muscle torques were much higher than models that did not account for co-contraction

Modeling and frequency tracking of marine mammal whistle calls

Submitted in partial fulfillment of the requirements for the degree of Master of Science at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution February 2009Marine mammal whistle calls present an attractive medium for covert underwater communications. High quality models of the whistle calls are needed in order to synthesize natural-sounding whistles with embedded information. Since the whistle calls are composed of frequency modulated harmonic tones, they are best modeled as a weighted superposition of harmonically related sinusoids. Previous research with bottlenose dolphin whistle calls has produced synthetic whistles that sound too “clean” for use in a covert communications system. Due to the sensitivity of the human auditory system, watermarking schemes that slightly modify the fundamental frequency contour have good potential for producing natural-sounding whistles embedded with retrievable watermarks. Structured total least squares is used with linear prediction analysis to track the time-varying fundamental frequency and harmonic amplitude contours throughout a whistle call. Simulation and experimental results demonstrate the capability to accurately model bottlenose dolphin whistle calls and retrieve embedded information from watermarked synthetic whistle calls. Different fundamental frequency watermarking schemes are proposed based on their ability to produce natural sounding synthetic whistles and yield suitable watermark detection and retrieval

Analysis and decomposition of frequency modulated multicomponent signals

Frequency modulated (FM) signals are studied in many research fields, including seismology, astrophysics, biology, acoustics, animal echolocation, radar and sonar. They are referred as multicomponent signals (MCS), as they are generally composed of multiple waveforms, with specific time-dependent frequencies, known as instantaneous frequencies (IFs). Many applications require the extraction of signal characteristics (i.e. amplitudes and IFs). that is why MCS decomposition is an important topic in signal processing. It consists of the recovery of each individual mode and it is often performed by IFs separation. The task becomes very challenging if the signal modes overlap in the TF domain, i.e. they interfere with each other, at the so-called non-separability region. For this reason, a general solution to MCS decomposition is not available yet. As a matter of fact, the existing methods addressing overlapping modes share the same limitations: they are parametric, therefore they adapt only to the assumed signal class, or they rely on signal-dependent and parametric TF representations; otherwise, they are interpolation techniques, i.e. they almost ignore the information corrupted by interference and they recover IF curve by some fitting procedures, resulting in high computational cost and bad performances against noise. This thesis aims at overcoming these drawbacks, providing efficient tools for dealing with MCS with interfering modes. An extended state-of-the-art revision is provided, as well as the mathematical tools and the main definitions needed to introduce the topic. Then, the problem is addressed following two main strategies: the former is an iterative approach that aims at enhancing MCS' resolution in the TF domain; the latter is a transform-based approach, that combines TF analysis and Radon Transform for separating individual modes. As main advantage, the methods derived from both the iterative and the transform-based approaches are non-parametric, as they do not require specific assumptions on the signal class. As confirmed by the experimental results and the comparative studies, the proposed approach contributes to the current state of the-art improvement

Automatic voice disorder recognition using acoustic amplitude modulation features

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.Includes bibliographical references (p. 114-117).An automatic dysphonia recognition system is designed that exploits amplitude modulations (AM) in voice using biologically-inspired models. This system recognizes general dysphonia and four subclasses: hyperfunction, A-P squeezing, paralysis, and vocal fold lesions. The models developed represent processing in the auditory system at the level of the cochlea, auditory nerve, and inferior colliculus. Recognition experiments using dysphonic sentence data obtained from the Kay Elemetrics Disordered Voice Database suggest that our system provides complementary information to state-of-the-art mel-cepstral features. A model for analyzing AM in dysphonic speech is also developed from a traditional communications engineering perspective. Through a case study of seven disordered voices, we show that different AM patterns occur in different frequency bands. This perspective challenges current dysphonia analysis methods that analyze AM in the time-domain signal.by Nicolas Malyska.S.M

A Study on Defect Identification of Planetary Gearbox under Large Speed Oscillation

Rotational speed of a reference shaft is the key information for planetary gearbox condition monitoring under nonstationary conditions. As the time-variant speed and load of planetary gearboxes result in time-variant characteristic frequencies as well as vibration magnitudes, the conventional methods tracking time-frequency ridge perform a poor robustness, especially for large speed variations. In this paper, two schemes, time-frequency ridge fusion and logarithm transformation, are proposed to track the targeted ridge curve reliably. Meanwhile, the identified ridge curve by logarithm scheme can be further refined by the time-frequency ridge fusion scheme. Hence, a procedure involving the proposed ridge estimation methods is presented to diagnose the planetary gearbox defects. Two simulation signals and a vibration signal collected from a planetary gearbox in practical engineering (provided by the conference on condition monitoring of machinery in nonstationary operations (CMMNO)) are used to verify the proposed methods. It is validated that the proposed methods can well-track the targeted ridge curve compared with two conventional methods. As a result, the characteristic frequency of each component in the planetary gearbox is clearly demonstrated and the inner race defect of one of the planet bearings is successfully discovered in the order spectrum depending on the derived expression of planet bearing fault frequency