10,709 research outputs found

    On the Static Diffie-Hellman Problem on Elliptic Curves over Extension Fields

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    Recent work by Koblitz and Menezes has highlighted the existence, in some cases, of apparent separations between the hardness of breaking discrete logarithms in a particular group, and the hardness of solving in that group problems to which the security of certain cryptosystems are provably related. We consider one such problem in the context of elliptic curves over extension fields, and report potential weaknesses of the Galbraith-Lin-Scott curves from EUROCRYPT 2009, as well as two very different practical attacks on the Oakley Key Determination Protocol curves

    Enabling Practical IPsec authentication for the Internet

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    On the Move to Meaningful Internet Systems 2006: OTM 2006 Workshops (First International Workshop on Information Security (IS'06), OTM Federated Conferences and workshops). Montpellier, Oct,/Nov. 2006There is a strong consensus about the need for IPsec, although its use is not widespread for end-to-end communications. One of the main reasons for this is the difficulty for authenticating two end-hosts that do not share a secret or do not rely on a common Certification Authority. In this paper we propose a modification to IKE to use reverse DNS and DNSSEC (named DNSSEC-to-IKE) to provide end-to-end authentication to Internet hosts that do not share any secret, without requiring the deployment of a new infrastructure. We perform a comparative analysis in terms of requirements, provided security and performance with state-of-the-art IKE authentication methods and with a recent proposal for IPv6 based on CGA. We conclude that DNSSEC-to-IKE enables the use of IPsec in a broad range of scenarios in which it was not applicable, at the price of offering slightly less security and incurring in higher performance costs.Universidad de Montpellier IIPublicad

    Adaptive colour change and background choice behaviour in peppered moth caterpillars is mediated by extraocular photoreception

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    Light sensing by tissues distinct from the eye occurs in diverse animal groups, enabling circadian control and phototactic behaviour. Extraocular photoreceptors may also facilitate rapid colour change in cephalopods and lizards, but little is known about the sensory system that mediates slow colour change in arthropods. We previously reported that slow colour change in twig-mimicking caterpillars of the peppered moth (Biston betularia) is a response to achromatic and chromatic visual cues. Here we show that the perception of these cues, and the resulting phenotypic responses, does not require ocular vision. Caterpillars with completely obscured ocelli remained capable of enhancing their crypsis by changing colour and choosing to rest on colour-matching twigs. A suite of visual genes, expressed across the larval integument, likely plays a key role in the mechanism. To our knowledge, this is the first evidence that extraocular colour sensing can mediate pigment-based colour change and behaviour in an arthropod

    A kilobit hidden SNFS discrete logarithm computation

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    We perform a special number field sieve discrete logarithm computation in a 1024-bit prime field. To our knowledge, this is the first kilobit-sized discrete logarithm computation ever reported for prime fields. This computation took a little over two months of calendar time on an academic cluster using the open-source CADO-NFS software. Our chosen prime pp looks random, and p−−1p--1 has a 160-bit prime factor, in line with recommended parameters for the Digital Signature Algorithm. However, our p has been trapdoored in such a way that the special number field sieve can be used to compute discrete logarithms in F_p∗\mathbb{F}\_p^* , yet detecting that p has this trapdoor seems out of reach. Twenty-five years ago, there was considerable controversy around the possibility of back-doored parameters for DSA. Our computations show that trapdoored primes are entirely feasible with current computing technology. We also describe special number field sieve discrete log computations carried out for multiple weak primes found in use in the wild. As can be expected from a trapdoor mechanism which we say is hard to detect, our research did not reveal any trapdoored prime in wide use. The only way for a user to defend against a hypothetical trapdoor of this kind is to require verifiably random primes

    Focal Spot, Spring 1979

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    https://digitalcommons.wustl.edu/focal_spot_archives/1023/thumbnail.jp

    Bronchiolitis Management: Development of an Australasian Evidence Base

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    Bronchiolitis is a common respiratory illness and the leading cause of hospitalisation for infants in Australia and New Zealand. Management for bronchiolitis is well defined and constitutes supportive treatment. However, despite the availability of high-level evidence, there remains substantial variation in the care. This research provides clinicians with information and resources to promote the delivery of evidenced-based care to infants presenting or admitted to hospital with bronchiolitis

    Secure time information in the internet key exchange protocol

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    Many network services and protocols can work correctly only when freshness of messages sent between participants is assured and when the protocol parties’ internal clocks are adjusted. In this paper we present a novel, secure and fast procedure which can be used to ensure data freshness and clock synchronization between two communicating parties. Next, we show how this solution can be used in other cryptographic protocols. As an example of application we apply our approach to the Internet Key Exchange (IKE) protocol family

    Evaluating the Role of the Steroid and Xenobiotic Receptor (SXR/PXR) in PCB-153 Metabolism and Protection against Associated Adverse Effects during Perinatal and Chronic Exposure in Mice.

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    BACKGROUND:Polychlorinated biphenyls (PCBs) are environmental toxicants; PCB exposure has been associated with adverse effects on wildlife and humans. However, the mechanisms underlying these adverse effects are not fully understood. The steroid and xenobiotic receptor [SXR; also known as the pregnane X receptor (PXR) and formally known as NR1I2] is a nuclear hormone receptor that regulates inducible metabolism of drugs and xenobiotics and is activated or inhibited by various PCB congeners. OBJECTIVES:The aim of this study was to investigate the effects of exposure to PCB-153, the most prevalent PCB congener in human tissues, on SXR knockout mice (SXRKO) and to elucidate the role of SXR in PCB-153 metabolism and promotion of its harmful effects. METHODS:Wild-type (WT) and SXRKO mice were chronically or perinatally exposed to a low dose (54ÎŒg/kg/d) of PCB-153. Blood, livers, and spleens were analyzed using transcriptome sequencing (RNA-seq) and molecular techniques to investigate the impacts of exposure on metabolism, oxidative stress, and hematological parameters. RESULTS:SXRKO mice perinatally exposed to PCB-153 displayed elevated oxidative stress, symptoms of hemolytic anemia, and premature death. Transcriptomal analysis revealed that expression of genes involved in metabolic processes was altered in SXRKO mice. Elevated levels of the PCB-153 metabolite, 3-OH-PCB-153, were found in exposed SXRKO mice compared to exposed WT mice. Blood hemoglobin (HGB) levels were lower throughout the lifespan, and the occurrence of intestinal tumors was larger in SXRKO mice chronically exposed to PCB-153 compared to vehicle and WT controls. DISCUSSION:Our results suggest that altered metabolism induced by SXR loss of function resulted in the accumulation of hydroxylated metabolites upon exposure to PCB-153, leading to oxidative stress, hemolytic anemia, and tumor development in a mouse model. These results support a major role for SXR/PXR in protection against xenobiotic-induced oxidative stress by maintaining proper metabolism in response to PCB-153 exposure. This role of SXR could be generally applicable to other environmental toxicants as well as pharmaceutical drugs. https://doi.org/10.1289/EHP6262
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