45,025 research outputs found
The Attraction Effect in Information Visualization
International audienceâThe attraction effect is a well-studied cognitive bias in decision making research, where one's choice between two alternatives is influenced by the presence of an irrelevant (dominated) third alternative. We examine whether this cognitive bias, so far only tested with three alternatives and simple presentation formats such as numerical tables, text and pictures, also appears in visualiza-tions. Since visualizations can be used to support decision making â e.g., when choosing a house to buy or an employee to hire â a systematic bias could have important implications. In a first crowdsource experiment, we indeed partially replicated the attraction effect with three alternatives presented as a numerical table, and observed similar effects when they were presented as a scatterplot. In a second experiment, we investigated if the effect extends to larger sets of alternatives, where the number of alternatives is too large for numerical tables to be practical. Our findings indicate that the bias persists for larger sets of alternatives presented as scatterplots. We discuss implications for future research on how to further study and possibly alleviate the attraction effect
Visualizing reciprocity in an online community to motivate participation
Online communities thrive on their membersâ participation and contributions. Continuous encouragement of participation of these members is vital for an online community. Social visualizations are one of the methods to make members explicitly aware of their connections and relationships. There are numerous ways to visually represent information, current-status, power, and acceptance of members in an online community. In this thesis I present a design of a visualization representing the evolving reciprocity of relationships among users based on the comments they give to each otherâs posts. The purpose of the visualization is to emphasize and hopefully trigger a common bond in the community and thereby increase their participation. We developed and deployed the visualization in an online community called âWISETalesâ where women in science and engineering share personal stories. We also deployed modified and improved versions of the visualization in two other communities, I-Help class discussion forums and the Vegatopia discussion forum for vegetarians. In this thesis we present the results of the evaluation in these three communities. The results unfortunately, were negative. Even though separate explanations for the lack of motivational effect can be found in each of the experiments, it seems that the chosen motivational approach was too gentle to encourage participation. It seems for reciprocation to take place, the users need to be committed to the community and already have some other underlying motivation to participate actively. The visualization also should provide some new information that they werenât aware of previously. This was not the case with the users in the three chosen communities. WISETales was too new and can barely be called a community. I-Help was not a community, but a place for student to post questions for the teacher to answer. Vegatopia, in contrast, is well established, active community, where people know each other, and engage in conversations with each other. The visualization did not provide any new information for them that they didnât know and only served as a brief attraction for a day (novelty effect). We are still optimistic, however, that the visualization may be useful for active and too dynamic communities where people are unaware of their social relationships because they are too many, for example, social network sites like Twitter
Conditional t-SNE: Complementary t-SNE embeddings through factoring out prior information
Dimensionality reduction and manifold learning methods such as t-Distributed
Stochastic Neighbor Embedding (t-SNE) are routinely used to map
high-dimensional data into a 2-dimensional space to visualize and explore the
data. However, two dimensions are typically insufficient to capture all
structure in the data, the salient structure is often already known, and it is
not obvious how to extract the remaining information in a similarly effective
manner. To fill this gap, we introduce \emph{conditional t-SNE} (ct-SNE), a
generalization of t-SNE that discounts prior information from the embedding in
the form of labels. To achieve this, we propose a conditioned version of the
t-SNE objective, obtaining a single, integrated, and elegant method. ct-SNE has
one extra parameter over t-SNE; we investigate its effects and show how to
efficiently optimize the objective. Factoring out prior knowledge allows
complementary structure to be captured in the embedding, providing new
insights. Qualitative and quantitative empirical results on synthetic and
(large) real data show ct-SNE is effective and achieves its goal
Trains, tails and loops of partially adsorbed semi-flexible filaments
Polymer adsorption is a fundamental problem in statistical mechanics that has
direct relevance to diverse disciplines ranging from biological lubrication to
stability of colloidal suspensions. We combine experiments with computer
simulations to investigate depletion induced adsorption of semi-flexible
polymers onto a hard-wall. Three dimensional filament configurations of
partially adsorbed F-actin polymers are visualized with total internal
reflection fluorescence microscopy. This information is used to determine the
location of the adsorption/desorption transition and extract the statistics of
trains, tails and loops of partially adsorbed filament configurations. In
contrast to long flexible filaments which primarily desorb by the formation of
loops, the desorption of stiff, finite-sized filaments is largely driven by
fluctuating filament tails. Simulations quantitatively reproduce our
experimental data and allow us to extract universal laws that explain scaling
of the adsorption-desorption transition with relevant microscopic parameters.
Our results demonstrate how the adhesion strength, filament stiffness, length,
as well as the configurational space accessible to the desorbed filament can be
used to design the characteristics of filament adsorption and thus engineer
properties of composite biopolymeric materials
Analysis of the lactose metabolism in E. coli using sum-of-squares decomposition
We provide a system-theoretic analysis of the mathematical model of lactose induction in E.coli which predicts the level of lactose induction into the cell for specified values of external lactose. Depending on the levels of external lactose and other parameters, the Lac operon is known to have a low steady state in which it is said to be turned off and high steady state where it is said to be turned on. Furthermore, the model has been shown experimentally to exhibit a bi-stable behavior. Using ideas from Lyapunov stability theory and sum-of-squares decomposition, we characterize the reachable state
space for different sets of initial conditions, calculating estimates of the regions of attraction of the biologically relevant equilibria of this system. The changes in the basins of attraction with changes in model parameters can be used to provide biological insight. Specifically, we explain the crucial role played by a small basal transcription rate in the Lac operon. We show that if the basal rate is below a threshold, the region of attraction of the low steady state grows significantly, indicating that system is trapped in the (off) mode, showing the importance of the basal rate of transcription
Physics-based visual characterization of molecular interaction forces
Molecular simulations are used in many areas of biotechnology, such as drug design and enzyme engineering. Despite the development of automatic computational protocols, analysis of molecular interactions is still a major aspect where human comprehension and intuition are key to accelerate, analyze, and propose modifications to the molecule of interest. Most visualization algorithms help the users by providing an accurate depiction of the spatial arrangement: the atoms involved in inter-molecular contacts. There are few tools that provide visual information on the forces governing molecular docking. However, these tools, commonly restricted to close interaction between atoms, do not consider whole simulation paths, long-range distances and, importantly, do not provide visual cues for a quick and intuitive comprehension of the energy functions (modeling intermolecular interactions) involved. In this paper, we propose visualizations designed to enable the characterization of interaction forces by taking into account several relevant variables such as molecule-ligand distance and the energy function, which is essential to understand binding affinities. We put emphasis on mapping molecular docking paths obtained from Molecular Dynamics or Monte Carlo simulations, and provide time-dependent visualizations for different energy components and particle resolutions: atoms, groups or residues. The presented visualizations have the potential to support domain experts in a more efficient drug or enzyme design process.Peer ReviewedPostprint (author's final draft
- âŠ