High-performance computing and communication models for solving the complex interdisciplinary problems on DPCS

The paper presents some advanced high performance (HPC) and parallel computing (PC) methodologies for solving a large space complex problem involving the integrated difference research areas. About eight interdisciplinary problems will be accurately solved on multiple computers communicating over the local area network. The mathematical modeling and a large sparse simulation of the interdisciplinary effort involve the area of science, engineering, biomedical, nanotechnology, software engineering, agriculture, image processing and urban planning. The specific methodologies of PC software under consideration include PVM, MPI, LUNA, MDC, OpenMP, CUDA and LINDA integrated with COMSOL and C++/C. There are different communication models of parallel programming, thus some definitions of parallel processing, distributed processing and memory types are explained for understanding the main contribution of this paper. The matching between the methodology of PC and the large sparse application depends on the domain of solution, the dimension of the targeted area, computational and communication pattern, the architecture of distributed parallel computing systems (DPCS), the structure of computational complexity and communication cost. The originality of this paper lies in obtaining the complex numerical model dealing with a large scale partial differential equation (PDE), discretization of finite difference (FDM) or finite element (FEM) methods, numerical simulation, high-performance simulation and performance measurement. The simulation of PDE will perform by sequential and parallel algorithms to visualize the complex model in high-resolution quality. In the context of a mathematical model, various independent and dependent parameters present the complex and real phenomena of the interdisciplinary application. As a model executes, these parameters can be manipulated and changed. As an impact, some chemical or mechanical properties can be predicted based on the observation of parameter changes. The methodologies of parallel programs build on the client-server model, slave-master model and fragmented model. HPC of the communication model for solving the interdisciplinary problems above will be analyzed using a flow of the algorithm, numerical analysis and the comparison of parallel performance evaluations. In conclusion, the integration of HPC, communication model, PC software, performance and numerical analysis happens to be an important approach to fulfill the matching requirement and optimize the solution of complex interdisciplinary problems

A manifesto for future generation cloud computing: research directions for the next decade

The Cloud computing paradigm has revolutionised the computer science horizon during the past decade and has enabled the emergence of computing as the fifth utility. It has captured significant attention of academia, industries, and government bodies. Now, it has emerged as the backbone of modern economy by offering subscription-based services anytime, anywhere following a pay-as-you-go model. This has instigated (1) shorter establishment times for start-ups, (2) creation of scalable global enterprise applications, (3) better cost-to-value associativity for scientific and high performance computing applications, and (4) different invocation/execution models for pervasive and ubiquitous applications. The recent technological developments and paradigms such as serverless computing, software-defined networking, Internet of Things, and processing at network edge are creating new opportunities for Cloud computing. However, they are also posing several new challenges and creating the need for new approaches and research strategies, as well as the re-evaluation of the models that were developed to address issues such as scalability, elasticity, reliability, security, sustainability, and application models. The proposed manifesto addresses them by identifying the major open challenges in Cloud computing, emerging trends, and impact areas. It then offers research directions for the next decade, thus helping in the realisation of Future Generation Cloud Computing

Timely processing of big data in collaborative large-scale distributed systems

Today’s Big Data phenomenon, characterized by huge volumes of data produced at very high rates by heterogeneous and geographically dispersed sources, is fostering the employment of large-scale distributed systems in order to leverage parallelism, fault tolerance and locality awareness with the aim of delivering suitable performances. Among the several areas where Big Data is gaining increasing significance, the protection of Critical Infrastructure is one of the most strategic since it impacts on the stability and safety of entire countries. Intrusion detection mechanisms can benefit a lot from novel Big Data technologies because these allow to exploit much more information in order to sharpen the accuracy of threats discovery. A key aspect for increasing even more the amount of data at disposal for detection purposes is the collaboration (meant as information sharing) among distinct actors that share the common goal of maximizing the chances to recognize malicious activities earlier. Indeed, if an agreement can be found to share their data, they all have the possibility to definitely improve their cyber defenses. The abstraction of Semantic Room (SR) allows interested parties to form trusted and contractually regulated federations, the Semantic Rooms, for the sake of secure information sharing and processing. Another crucial point for the effectiveness of cyber protection mechanisms is the timeliness of the detection, because the sooner a threat is identified, the faster proper countermeasures can be put in place so as to confine any damage. Within this context, the contributions reported in this thesis are threefold * As a case study to show how collaboration can enhance the efficacy of security tools, we developed a novel algorithm for the detection of stealthy port scans, named R-SYN (Ranked SYN port scan detection). We implemented it in three distinct technologies, all of them integrated within an SR-compliant architecture that allows for collaboration through information sharing: (i) in a centralized Complex Event Processing (CEP) engine (Esper), (ii) in a framework for distributed event processing (Storm) and (iii) in Agilis, a novel platform for batch-oriented processing which leverages the Hadoop framework and a RAM-based storage for fast data access. Regardless of the employed technology, all the evaluations have shown that increasing the number of participants (that is, increasing the amount of input data at disposal), allows to improve the detection accuracy. The experiments made clear that a distributed approach allows for lower detection latency and for keeping up with higher input throughput, compared with a centralized one. * Distributing the computation over a set of physical nodes introduces the issue of improving the way available resources are assigned to the elaboration tasks to execute, with the aim of minimizing the time the computation takes to complete. We investigated this aspect in Storm by developing two distinct scheduling algorithms, both aimed at decreasing the average elaboration time of the single input event by decreasing the inter-node traffic. Experimental evaluations showed that these two algorithms can improve the performance up to 30%. * Computations in online processing platforms (like Esper and Storm) are run continuously, and the need of refining running computations or adding new computations, together with the need to cope with the variability of the input, requires the possibility to adapt the resource allocation at runtime, which entails a set of additional problems. Among them, the most relevant concern how to cope with incoming data and processing state while the topology is being reconfigured, and the issue of temporary reduced performance. At this aim, we also explored the alternative approach of running the computation periodically on batches of input data: although it involves a performance penalty on the elaboration latency, it allows to eliminate the great complexity of dynamic reconfigurations. We chose Hadoop as batch-oriented processing framework and we developed some strategies specific for dealing with computations based on time windows, which are very likely to be used for pattern recognition purposes, like in the case of intrusion detection. Our evaluations provided a comparison of these strategies and made evident the kind of performance that this approach can provide

A Hierarchical Filtering-Based Monitoring Architecture for Large-scale Distributed Systems

On-line monitoring is essential for observing and improving the reliability and performance of large-scale distributed (LSD) systems. In an LSD environment, large numbers of events are generated by system components during their execution and interaction with external objects (e.g. users or processes). These events must be monitored to accurately determine the run-time behavior of an LSD system and to obtain status information that is required for debugging and steering applications. However, the manner in which events are generated in an LSD system is complex and represents a number of challenges for an on-line monitoring system. Correlated events axe generated concurrently and can occur at multiple locations distributed throughout the environment. This makes monitoring an intricate task and complicates the management decision process. Furthermore, the large number of entities and the geographical distribution inherent with LSD systems increases the difficulty of addressing traditional issues, such as performance bottlenecks, scalability, and application perturbation. This dissertation proposes a scalable, high-performance, dynamic, flexible and non-intrusive monitoring architecture for LSD systems. The resulting architecture detects and classifies interesting primitive and composite events and performs either a corrective or steering action. When appropriate, information is disseminated to management applications, such as reactive control and debugging tools. The monitoring architecture employs a novel hierarchical event filtering approach that distributes the monitoring load and limits event propagation. This significantly improves scalability and performance while minimizing the monitoring intrusiveness. The architecture provides dynamic monitoring capabilities through: subscription policies that enable applications developers to add, delete and modify monitoring demands on-the-fly, an adaptable configuration that accommodates environmental changes, and a programmable environment that facilitates development of self-directed monitoring tasks. Increased flexibility is achieved through a declarative and comprehensive monitoring language, a simple code instrumentation process, and automated monitoring administration. These elements substantially relieve the burden imposed by using on-line distributed monitoring systems. In addition, the monitoring system provides techniques to manage the trade-offs between various monitoring objectives. The proposed solution offers improvements over related works by presenting a comprehensive architecture that considers the requirements and implied objectives for monitoring large-scale distributed systems. This architecture is referred to as the HiFi monitoring system. To demonstrate effectiveness at debugging and steering LSD systems, the HiFi monitoring system has been implemented at the Old Dominion University for monitoring the Interactive Remote Instruction (IRI) system. The results from this case study validate that the HiFi system achieves the objectives outlined in this thesis

Application of Machine Learning in Healthcare and Medicine: A Review

This extensive literature review investigates the integration of Machine Learning (ML) into the healthcare sector, uncovering its potential, challenges, and strategic resolutions. The main objective is to comprehensively explore how ML is incorporated into medical practices, demonstrate its impact, and provide relevant solutions. The research motivation stems from the necessity to comprehend the convergence of ML and healthcare services, given its intricate implications. Through meticulous analysis of existing research, this method elucidates the broad spectrum of ML applications in disease prediction and personalized treatment. The research's precision lies in dissecting methodologies, scrutinizing studies, and extrapolating critical insights. The article establishes that ML has succeeded in various aspects of medical care. In certain studies, ML algorithms, especially Convolutional Neural Networks (CNNs), have achieved high accuracy in diagnosing diseases such as lung cancer, colorectal cancer, brain tumors, and breast tumors. Apart from CNNs, other algorithms like SVM, RF, k-NN, and DT have also proven effective. Evaluations based on accuracy and F1-score indicate satisfactory results, with some studies exceeding 90% accuracy. This principal finding underscores the impressive accuracy of ML algorithms in diagnosing diverse medical conditions. This outcome signifies the transformative potential of ML in reshaping conventional diagnostic techniques. Discussions revolve around challenges like data quality, security risks, potential misinterpretations, and obstacles in integrating ML into clinical realms. To mitigate these, multifaceted solutions are proposed, encompassing standardized data formats, robust encryption, model interpretation, clinician training, and stakeholder collaboration

Victima: Drastically Increasing Address Translation Reach by Leveraging Underutilized Cache Resources

Address translation is a performance bottleneck in data-intensive workloads due to large datasets and irregular access patterns that lead to frequent high-latency page table walks (PTWs). PTWs can be reduced by using (i) large hardware TLBs or (ii) large software-managed TLBs. Unfortunately, both solutions have significant drawbacks: increased access latency, power and area (for hardware TLBs), and costly memory accesses, the need for large contiguous memory blocks, and complex OS modifications (for software-managed TLBs). We present Victima, a new software-transparent mechanism that drastically increases the translation reach of the processor by leveraging the underutilized resources of the cache hierarchy. The key idea of Victima is to repurpose L2 cache blocks to store clusters of TLB entries, thereby providing an additional low-latency and high-capacity component that backs up the last-level TLB and thus reduces PTWs. Victima has two main components. First, a PTW cost predictor (PTW-CP) identifies costly-to-translate addresses based on the frequency and cost of the PTWs they lead to. Second, a TLB-aware cache replacement policy prioritizes keeping TLB entries in the cache hierarchy by considering (i) the translation pressure (e.g., last-level TLB miss rate) and (ii) the reuse characteristics of the TLB entries. Our evaluation results show that in native (virtualized) execution environments Victima improves average end-to-end application performance by 7.4% (28.7%) over the baseline four-level radix-tree-based page table design and by 6.2% (20.1%) over a state-of-the-art software-managed TLB, across 11 diverse data-intensive workloads. Victima (i) is effective in both native and virtualized environments, (ii) is completely transparent to application and system software, and (iii) incurs very small area and power overheads on a modern high-end CPU.Comment: To appear in 56th IEEE/ACM International Symposium on Microarchitecture (MICRO), 202