AEVUM: Personalized Health Monitoring System

Advancement in the field of sensors and other portable technologies have resulted in a bevy of health monitoring devices such as blue-tooth and Wi-Fi enabled weighing scales and wearables which help individuals monitor their personal health. This collected information provides a plethora of data points over intervals of time that a primary care physician can utilize to gain a holistic understanding of an individual’s health and provide a more effective and personalized treatment. A drawback of the existing health monitoring devices is that they are not integrated with the professional medical infrastructure. With the wealth of information collected, it is also not feasible for a physician to look through all the data to obtain relevant information or patterns from multiple health monitoring systems. Therefore, it would be beneficial to have a single platform of hardware devices to monitor and collect data and a software application to securely store the collected information, identify patterns for analysis, and summarize the data for the physician and the patient. The aim of this study was to design and develop an unobtrusive, user friendly system, Aevum, which would integrate technology, adapt itself to changes in consumer behavior and integrate with the existing healthcare infrastructure to help an individual monitor their health in a customized manner. Aevum is a multi-device system consisting of a smart, puck-shaped hardware product, a wristband and a software application available to the patient as well as the physician. In addition to monitoring vitals such as heart rate, blood pressure, body temperature and weight, Aevum can monitor environmental factors that affect an individual’s health and uses personalized metrics such as precise calorie intake and medication management to monitor health. This allows the user to personalize Aevum based on their health condition. Finally, Aevum identifies patterns of anomalies in the collected data and compiles the information which can be accessed by the physician to assist in their treatment

Robust and Analytical Cardiovascular Sensing

The photoplethysmogram (PPG) is a noninvasive cardiovascular signal related to the pulsatile volume of blood in tissue. The PPG is user-friendly and has the potential to be measured remotely in a contactless manner using a regular RGB camera. In this dissertation, we study the modeling and analytics of PPG signal to facilitate its applications in both robust and remote cardiovascular sensing. In the first part of this dissertation, we study the remote photoplethysmography (rPPG) and present a robust and efficient rPPG system to extract pulse rate (PR) and pulse rate variability (PRV) from face videos. Compared with prior art, our proposed system can achieve accurate PR and PRV estimates even when the video contains significant subject motion and environmental illumination change. In the second part of the dissertation, we present a novel frequency tracking algorithm called Adaptive Multi-Trace Carving (AMTC) to address the micro signal extraction problems. AMTC enables an accurate detection and estimation of one or more subtle frequency components in a very low signal-to-noise ratio condition. In the third part of the dissertation, the relation between electrocardiogram (ECG) and PPG is studied and the waveform of ECG is inferred via the PPG signals. In order to address this cardiovascular inverse problem, a transform is proposed to map the discrete cosine transform coefficients of each PPG cycle to those of the corresponding ECG cycle. As the first work to address this biomedical inverse problem, this line of research enables a full utilization of the easy accessibility of PPG and the clinical authority of ECG for better preventive healthcare

Review of Wearable Devices and Data Collection Considerations for Connected Health

Wearable sensor technology has gradually extended its usability into a wide range of well-known applications. Wearable sensors can typically assess and quantify the wearer’s physiology and are commonly employed for human activity detection and quantified self-assessment. Wearable sensors are increasingly utilised to monitor patient health, rapidly assist with disease diagnosis, and help predict and often improve patient outcomes. Clinicians use various self-report questionnaires and well-known tests to report patient symptoms and assess their functional ability. These assessments are time consuming and costly and depend on subjective patient recall. Moreover, measurements may not accurately demonstrate the patient’s functional ability whilst at home. Wearable sensors can be used to detect and quantify specific movements in different applications. The volume of data collected by wearable sensors during long-term assessment of ambulatory movement can become immense in tuple size. This paper discusses current techniques used to track and record various human body movements, as well as techniques used to measure activity and sleep from long-term data collected by wearable technology devices

Earth benefits from NASA research and technology. Life sciences applications

This document provides a representative sampling of examples of Earth benefits in life-sciences-related applications, primarily in the area of medicine and health care, but also in agricultural productivity, environmental monitoring and safety, and the environment. This brochure is not intended as an exhaustive listing, but as an overview to acquaint the reader with the breadth of areas in which the space life sciences have, in one way or another, contributed a unique perspective to the solution of problems on Earth. Most of the examples cited were derived directly from space life sciences research and technology. Some examples resulted from other space technologies, but have found important life sciences applications on Earth. And, finally, we have included several areas in which Earth benefits are anticipated from biomedical and biological research conducted in support of future human exploration missions

Camera-Based Heart Rate Extraction in Noisy Environments

Remote photoplethysmography (rPPG) is a non-invasive technique that benefits from video to measure vital signs such as the heart rate (HR). In rPPG estimation, noise can introduce artifacts that distort rPPG signal and jeopardize accurate HR measurement. Considering that most rPPG studies occurred in lab-controlled environments, the issue of noise in realistic conditions remains open. This thesis aims to examine the challenges of noise in rPPG estimation in realistic scenarios, specifically investigating the effect of noise arising from illumination variation and motion artifacts on the predicted rPPG HR. To mitigate the impact of noise, a modular rPPG measurement framework, comprising data preprocessing, region of interest, signal extraction, preparation, processing, and HR extraction is developed. The proposed pipeline is tested on the LGI-PPGI-Face-Video-Database public dataset, hosting four different candidates and real-life scenarios. In the RoI module, raw rPPG signals were extracted from the dataset using three machine learning-based face detectors, namely Haarcascade, Dlib, and MediaPipe, in parallel. Subsequently, the collected signals underwent preprocessing, independent component analysis, denoising, and frequency domain conversion for peak detection. Overall, the Dlib face detector leads to the most successful HR for the majority of scenarios. In 50% of all scenarios and candidates, the average predicted HR for Dlib is either in line or very close to the average reference HR. The extracted HRs from the Haarcascade and MediaPipe architectures make up 31.25% and 18.75% of plausible results, respectively. The analysis highlighted the importance of fixated facial landmarks in collecting quality raw data and reducing noise