23,834 research outputs found
Learning and comparing functional connectomes across subjects
Functional connectomes capture brain interactions via synchronized
fluctuations in the functional magnetic resonance imaging signal. If measured
during rest, they map the intrinsic functional architecture of the brain. With
task-driven experiments they represent integration mechanisms between
specialized brain areas. Analyzing their variability across subjects and
conditions can reveal markers of brain pathologies and mechanisms underlying
cognition. Methods of estimating functional connectomes from the imaging signal
have undergone rapid developments and the literature is full of diverse
strategies for comparing them. This review aims to clarify links across
functional-connectivity methods as well as to expose different steps to perform
a group study of functional connectomes
A micropower centroiding vision processor
Published versio
Comparing the writing style of real and artificial papers
Recent years have witnessed the increase of competition in science. While
promoting the quality of research in many cases, an intense competition among
scientists can also trigger unethical scientific behaviors. To increase the
total number of published papers, some authors even resort to software tools
that are able to produce grammatical, but meaningless scientific manuscripts.
Because automatically generated papers can be misunderstood as real papers, it
becomes of paramount importance to develop means to identify these scientific
frauds. In this paper, I devise a methodology to distinguish real manuscripts
from those generated with SCIGen, an automatic paper generator. Upon modeling
texts as complex networks (CN), it was possible to discriminate real from fake
papers with at least 89\% of accuracy. A systematic analysis of features
relevance revealed that the accessibility and betweenness were useful in
particular cases, even though the relevance depended upon the dataset. The
successful application of the methods described here show, as a proof of
principle, that network features can be used to identify scientific gibberish
papers. In addition, the CN-based approach can be combined in a straightforward
fashion with traditional statistical language processing methods to improve the
performance in identifying artificially generated papers.Comment: To appear in Scientometrics (2015
A graph-based mathematical morphology reader
This survey paper aims at providing a "literary" anthology of mathematical
morphology on graphs. It describes in the English language many ideas stemming
from a large number of different papers, hence providing a unified view of an
active and diverse field of research
Image informatics strategies for deciphering neuronal network connectivity
Brain function relies on an intricate network of highly dynamic neuronal connections that rewires dramatically under the impulse of various external cues and pathological conditions. Among the neuronal structures that show morphologi- cal plasticity are neurites, synapses, dendritic spines and even nuclei. This structural remodelling is directly connected with functional changes such as intercellular com- munication and the associated calcium-bursting behaviour. In vitro cultured neu- ronal networks are valuable models for studying these morpho-functional changes. Owing to the automation and standardisation of both image acquisition and image analysis, it has become possible to extract statistically relevant readout from such networks. Here, we focus on the current state-of-the-art in image informatics that enables quantitative microscopic interrogation of neuronal networks. We describe the major correlates of neuronal connectivity and present workflows for analysing them. Finally, we provide an outlook on the challenges that remain to be addressed, and discuss how imaging algorithms can be extended beyond in vitro imaging studies
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