Surgical Subtask Automation for Intraluminal Procedures using Deep Reinforcement Learning

Intraluminal procedures have opened up a new sub-field of minimally invasive surgery that use flexible instruments to navigate through complex luminal structures of the body, resulting in reduced invasiveness and improved patient benefits. One of the major challenges in this field is the accurate and precise control of the instrument inside the human body. Robotics has emerged as a promising solution to this problem. However, to achieve successful robotic intraluminal interventions, the control of the instrument needs to be automated to a large extent. The thesis first examines the state-of-the-art in intraluminal surgical robotics and identifies the key challenges in this field, which include the need for safe and effective tool manipulation, and the ability to adapt to unexpected changes in the luminal environment. To address these challenges, the thesis proposes several levels of autonomy that enable the robotic system to perform individual subtasks autonomously, while still allowing the surgeon to retain overall control of the procedure. The approach facilitates the development of specialized algorithms such as Deep Reinforcement Learning (DRL) for subtasks like navigation and tissue manipulation to produce robust surgical gestures. Additionally, the thesis proposes a safety framework that provides formal guarantees to prevent risky actions. The presented approaches are evaluated through a series of experiments using simulation and robotic platforms. The experiments demonstrate that subtask automation can improve the accuracy and efficiency of tool positioning and tissue manipulation, while also reducing the cognitive load on the surgeon. The results of this research have the potential to improve the reliability and safety of intraluminal surgical interventions, ultimately leading to better outcomes for patients and surgeons

Image Analysis via Applied Harmonic Analysis : Perceptual Image Quality Assessment, Visual Servoing, and Feature Detection

Certain systems of analyzing functions developed in the field of applied harmonic analysis are specifically designed to yield efficient representations of structures which are characteristic of common classes of two-dimensional signals, like images. In particular, functions in these systems are typically sensitive to features that define the geometry of a signal, like edges and curves in the case of images. These properties make them ideal candidates for a wide variety of tasks in image processing and image analysis. This thesis discusses three recently developed approaches to utilizing systems of wavelets, shearlets, and alpha-molecules in specific image analysis tasks. First, a perceptual image similarity measure is introduced that is solely based on the coefficients obtained from six discrete Haar wavelet filters but yields state of the art correlations with human opinion scores on large benchmark databases. The second application concerns visual servoing, which is a technique for controlling the motion of a robot by using feedback from a visual sensor. In particular, it will be investigated how the coefficients yielded by discrete wavelet and shearlet transforms can be used as the visual features that control the motion of a robot with six degrees of freedom. Finally, a novel framework for the detection and characterization of features such as edges, ridges, and blobs in two-dimensional images is presented and evaluated in extensive numerical experiments. Here, versatile and robust feature detectors are obtained by exploiting the special symmetry properties of directionally sensitive analyzing functions in systems created within the recently introduced alpha-molecule framework

Image Analysis via Applied Harmonic Analysis : Perceptual Image Quality Assessment, Visual Servoing, and Feature Detection

Certain systems of analyzing functions developed in the field of applied harmonic analysis are specifically designed to yield efficient representations of structures which are characteristic of common classes of two-dimensional signals, like images. In particular, functions in these systems are typically sensitive to features that define the geometry of a signal, like edges and curves in the case of images. These properties make them ideal candidates for a wide variety of tasks in image processing and image analysis. This thesis discusses three recently developed approaches to utilizing systems of wavelets, shearlets, and alpha-molecules in specific image analysis tasks. First, a perceptual image similarity measure is introduced that is solely based on the coefficients obtained from six discrete Haar wavelet filters but yields state of the art correlations with human opinion scores on large benchmark databases. The second application concerns visual servoing, which is a technique for controlling the motion of a robot by using feedback from a visual sensor. In particular, it will be investigated how the coefficients yielded by discrete wavelet and shearlet transforms can be used as the visual features that control the motion of a robot with six degrees of freedom. Finally, a novel framework for the detection and characterization of features such as edges, ridges, and blobs in two-dimensional images is presented and evaluated in extensive numerical experiments. Here, versatile and robust feature detectors are obtained by exploiting the special symmetry properties of directionally sensitive analyzing functions in systems created within the recently introduced alpha-molecule framework