On delayed genetic regulatory networks with polytopic uncertainties: Robust stability analysis

Copyright [2008] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.In this paper, we investigate the robust asymptotic stability problem of genetic regulatory networks with time-varying delays and polytopic parameter uncertainties. Both cases of differentiable and nondifferentiable time-delays are considered, and the convex polytopic description is utilized to characterize the genetic network model uncertainties. By using a Lyapunov functional approach and linear matrix inequality (LMI) techniques, the stability criteria for the uncertain delayed genetic networks are established in the form of LMIs, which can be readily verified by using standard numerical software. An important feature of the results reported here is that all the stability conditions are dependent on the upper and lower bounds of the delays, which is made possible by using up-to-date techniques for achieving delay dependence. Another feature of the results lies in that a novel Lyapunov functional dependent on the uncertain parameters is utilized, which renders the results to be potentially less conservative than those obtained via a fixed Lyapunov functional for the entire uncertainty domain. A genetic network example is employed to illustrate the applicability and usefulness of the developed theoretical results

Robust filtering for stochastic genetic regulatory networks with time-varying delay

This is the post print version of the article. The official published version can be obtained from the link - Copyright 2009 Elsevier LtdThis paper addresses the robust filtering problem for a class of linear genetic regulatory networks (GRNs) with stochastic disturbances, parameter uncertainties and time delays. The parameter uncertainties are assumed to reside in a polytopic region, the stochastic disturbance is state-dependent described by a scalar Brownian motion, and the time-varying delays enter into both the translation process and the feedback regulation process. We aim to estimate the true concentrations of mRNA and protein by designing a linear filter such that, for all admissible time delays, stochastic disturbances as well as polytopic uncertainties, the augmented state estimation dynamics is exponentially mean square stable with an expected decay rate. A delay-dependent linear matrix inequality (LMI) approach is first developed to derive sufficient conditions that guarantee the exponential stability of the augmented dynamics, and then the filter gains are parameterized in terms of the solution to a set of LMIs. Note that LMIs can be easily solved by using standard software packages. A simulation example is exploited in order to illustrate the effectiveness of the proposed design procedures.This work was supported in part by the Biotechnology and Biological Sciences Research Council (BBSRC) of the U.K. under Grants BB/C506264/1 and 100/EGM17735, an International Joint Project sponsored by the Royal Society of the U.K., the Research Grants Council of Hong Kong under Grant HKU 7031/06P, the National Natural Science Foundation of China under Grant 60804028, and the Alexander von Humboldt Foundation of Germany

Robust stabilization for stochastic time-delay systems with polytopic uncertainties

This paper considers the problem of robust stabilization for stochastic time-delay systems with convex polytopic uncertainties. Sufficient conditions for the solvability of the problem are obtained by using parameter-independent and parameter-dependent Lyapunov functionals, respectively. It is shown that the result derived by a parameter-dependent Lyapunov functional is less conservative. A desired state feedback controller can be designed by solving a set of linear matrix inequalities. © 2004 IEEE.published_or_final_versio

Robust H∞ filtering for networked systems with multiple state delays

This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Taylor & Francis Ltd.In this paper, a new robust H∞ filter design problem is studied for a class of networked systems with multiple state-delays. Two kinds of incomplete measurements, namely, measurements with random delays and measurements with stochastic missing phenomenon, are simultaneously considered. Such incomplete measurements are induced by the limited bandwidth of communication networks, and are modelled as a linear function of a certain set of indicator functions that depend on the same stochastic variable. Attention is focused on the analysis and design problems of a full-order robust H∞ filter such that, for all admissible parameter uncertainties and all possible incomplete measurements, the filtering error dynamics is exponentially mean-square stable and a prescribed H∞ attenuation level is guaranteed. Some recently reported methodologies, such as delay-dependent and parameter-dependent stability analysis approaches, are employed to obtain less conservative results. Sufficient conditions, which are dependent on the occurrence probability of both the random sensor delay and missing measurement, are established for the existence of the desired filters in terms of certain linear matrix inequalities (LMIs). When these LMIs are feasible, the explicit expression of the desired filter can also be characterized. Finally, numerical examples are given to illustrate the effectiveness and applicability of the proposed design method.This work was supported by the National Natural Science Foundation of China under Grant 60574084, the National 863 Project of China under Grant 2006AA04Z428, and the National 973 Program of China under Grant 2002CB312200

A review of convex approaches for control, observation and safety of linear parameter varying and Takagi-Sugeno systems

This paper provides a review about the concept of convex systems based on Takagi-Sugeno, linear parameter varying (LPV) and quasi-LPV modeling. These paradigms are capable of hiding the nonlinearities by means of an equivalent description which uses a set of linear models interpolated by appropriately defined weighing functions. Convex systems have become very popular since they allow applying extended linear techniques based on linear matrix inequalities (LMIs) to complex nonlinear systems. This survey aims at providing the reader with a significant overview of the existing LMI-based techniques for convex systems in the fields of control, observation and safety. Firstly, a detailed review of stability, feedback, tracking and model predictive control (MPC) convex controllers is considered. Secondly, the problem of state estimation is addressed through the design of proportional, proportional-integral, unknown input and descriptor observers. Finally, safety of convex systems is discussed by describing popular techniques for fault diagnosis and fault tolerant control (FTC).Peer ReviewedPostprint (published version

Robust Stability Analysis and Synthesis for Switched Discrete-Time Systems with Time Delay

The problems of robust stability analysis and synthesis for a class of uncertain switched time-delay systems with polytopic type uncertainties are addressed. Based on the constructive use of an appropriate switched Lyapunov function, sufficient linear matrix inequalities (LMIs) conditions are investigated to make such systems a uniform quadratic stability with an L2-gain smaller than a given constant level. System synthesis is to design switched feedback schemes, whether based on state, output measurements, or by using dynamic output feedback, to guarantee that the corresponding closed-loop system satisfies the LMIs conditions. Two numerical examples are provided that demonstrate the efficiency of this approach

Mathematical control of complex systems 2013

Mathematical control of complex systems have already become an ideal research area for control engineers, mathematicians, computer scientists, and biologists to understand, manage, analyze, and interpret functional information/dynamical behaviours from real-world complex dynamical systems, such as communication systems, process control, environmental systems, intelligent manufacturing systems, transportation systems, and structural systems. This special issue aims to bring together the latest/innovative knowledge and advances in mathematics for handling complex systems. Topics include, but are not limited to the following: control systems theory (behavioural systems, networked control systems, delay systems, distributed systems, infinite-dimensional systems, and positive systems); networked control (channel capacity constraints, control over communication networks, distributed filtering and control, information theory and control, and sensor networks); and stochastic systems (nonlinear filtering, nonparametric methods, particle filtering, partial identification, stochastic control, stochastic realization, system identification)

Stability analysis and controller design for switched time-delay systems

In this thesis, the stability analysis and control synthesis for uncertain switched time-delay systems are investigated. It is known that a wide variety of real-world systems are subject to uncertainty and also time-delay in their dynamics. These characteristics, if not taken into consideration in analysis and synthesis, can lead to important problems such as performance degradation or instability in a control system. On the other hand, the switching phenomenon often appears in numerous applications, where abrupt change is inevitable in the system model. Switching behavior in this type of systems can be triggered either by time, or by the state of the system. A theoretical framework to study various features of switched systems in the presence of uncertainty and time-delay (both neutral and retarded) would be of particular interest in important applications such as network control systems, power systems and communication networks. To address the problem of robust stability for the class of uncertain switched systems with unknown time-varying delay discussed above, sufficient conditions in the form of linear matrix inequalities (LMI) are derived. An adaptive switching control algorithm is then proposed for the stabilization of uncertain discrete time-delay systems subject to disturbance. It is assumed that the discrete time-delay system is highly uncertain, such that a single fixed controller cannot stabilize it effectively. Sufficient conditions are provided subsequently for the stability of switched time-delay systems with polytopic-type uncertainties. Moreover, an adaptive control scheme is provided to stabilize the uncertain neutral time-delay systems when the upper bounds on the system uncertainties are not available a priori . Simulations are provided throughout the thesis to support the theoretical result

Discrete-time recurrent neural networks with time-varying delays: Exponential stability analysis

This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Elsevier LtdThis Letter is concerned with the analysis problem of exponential stability for a class of discrete-time recurrent neural networks (DRNNs) with time delays. The delay is of the time-varying nature, and the activation functions are assumed to be neither differentiable nor strict monotonic. Furthermore, the description of the activation functions is more general than the recently commonly used Lipschitz conditions. Under such mild conditions, we first prove the existence of the equilibrium point. Then, by employing a Lyapunov–Krasovskii functional, a unified linear matrix inequality (LMI) approach is developed to establish sufficient conditions for the DRNNs to be globally exponentially stable. It is shown that the delayed DRNNs are globally exponentially stable if a certain LMI is solvable, where the feasibility of such an LMI can be easily checked by using the numerically efficient Matlab LMI Toolbox. A simulation example is presented to show the usefulness of the derived LMI-based stability condition.This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC) of the UK under Grant GR/S27658/01, the Nuffield Foundation of the UK under Grant NAL/00630/G, the Alexander von Humboldt Foundation of Germany, the Natural Science Foundation of Jiangsu Education Committee of China (05KJB110154), the NSF of Jiangsu Province of China (BK2006064), and the National Natural Science Foundation of China (10471119)